INTRODUCTION AND OBJECTIVES: Aim of this research was estimation of stages and rate of survival oral mucosa grafts on different beds. METHODS: Seventy eight buccal and eighty six lingual grafts were harvested from 52 male Wister rats. Animal were 300 till 470 g of weight. Both types of graft were placed on a skeletal muscle (SM), subcutaneous fat (SCF) and tunica albuginea (TA). Histological research was effected for 2,4,7,14 days of observation with a coloration a hematoxylin and eosine. RESULTS: Survival of grafts has sequentially passed through all stages of a nonspecific inflammation. First stage was alteration (mean 2 days) with a strongly marked atrophy of an epithelium, a necrosis of muscular fibers of a graft, and also necrotic changes between graft and feeding bed. Next stage was an exudation and emigration (mean 2-4 days) with an infiltration with neutrophilic leukocytes of a graft with transfer to superficial layer of feeling bed. As a result there was edema of a bed‘s stroma . Third stage was a proliferation. There were reduction of necro-inflammatory processes and the leukocytic infiltration and new bloody vessel formation in a subepithelial basis of grafts. Majority of grafts began a proliferation stage since seventh day. The last stage was neoangiogenesis. In this stage the epithelial layer of a graft was recovered and granulatuion developed in a submucosal layer. The greatest activity of regenerative processes becomes perceptible from 7th to 14th days. Outcomes of transplantation estimated from 7 days. The best rate of survival was noted for buccal graft on tunica albuginea. Survival rates for buccal mucosa graft on TA, SM and SCF were 93.4% 90.7%, 81%. The worst rate of survival was for lingual graft on subcutaneous fat. Survival rates for lingual mucosa graft on TA, SM and SCF were 88.9%87.9%, 76.2%. CONCLUSIONS: Stages of interaction of difference grafts and feeding beds does not depend on type of a bed and grafts. There are absolutely the same stages in all situations. Intensity of the cellular answer, term of the specified stages and outcomes of grafting are various for difference grafts and beds. Peak of development of morphological characters, characteristic for each of stages defining at histological research depend on a type of a graft and a feeding bed. Necro-inflammatory changes of the buccal graft are replaced by proliferative processes in earlier terms, than in a lingual graft. There are more quickly start of proliferative and regenerative processes on a tunica albuginea and prolongation of stages alteration and an exudation on a subcutaneous fat.