ABSTRACTThe Malacca Strait, the Suez Canal and the Panama Canal play an important role in the global container shipping. To study the impact of main channel interruption on the container shipping, we analysed statistical data on all routes operated by the top 100 global container liner companies and constructed a network model. We selected four topological metrics to measure the network’s connectivity and used the network weekly total shipping capacity and average shortest shipping time to measure the network’s transportation capacity and transportation time. The interruption of the main channel is simulated, and the changes in the metrics are analysed. The results indicated that the network’s vulnerability is sensitive to main channel interruption. If the Malacca Strait is interrupted, the network’s prosperity degree fall by almost half and the network’s transportation time increase by more than a quarter if the Suez Canal is interrupted. In addition, East Asian and European container liner shipping have more than 50% dependence on the Malacca Strait and the Suez Canal. Moreover, the container transport time between ports in East Asia, Europe, and North America and the rest of the world increases by an average of 4–9 days in the main channel interruption.