Abstract With the advantage of efficient aggregation of flexible resources on the demand side, virtual power plants have been widely considered as one of the effective solutions to solve the lack of large-scale access systems and regulation capacity of new energy. Aiming at the problem of how the flexible resources of the virtual power plant can effectively participate in the optimal operation of hierarchical zoning of the power grid, this paper takes the aggregation of flexible resources of the virtual power plant to alleviate multiple line overload as an example. By deducing the transfer factor matrix under the linearized AC power flow model, an event-triggered hierarchical zoning method of flexible resources of virtual power plants considering resource effectiveness is proposed. The effectiveness of the algorithm is verified in several network examples, which provides a new idea for the virtual power plant to participate in the optimal operation of various levels and regions of the power grid.