High-performance facades play an important role in achieving Net-Zero goals by 2050. As a facade manufacturing technology, 3D printing offers the opportunity to create site-specific and high-performance building envelopes. In this manuscript, the thermal performance of components fabricated with different Material Extrusion methods is studied experimentally, and the fabrication time is calculated, thereby examining both performance and fabrication viability. More specifically, this manuscript investigates the thermal performance of 3D-printed facades using Hollow-Core 3D printing (HC3DP) and explores the potential of this novel approach in creating thermally insulating, lightweight, and translucent building envelopes. The research compares the thermal resistance of HC3DP specimens to conventional material extrusion methods, such as desktop 3D printers, and granular-based, large-scale pellet extrusion. Different methods are used to determine the thermal resistance of specimens, including the dynamic thermal conductivity measurement for the desktop 3D-printed (3DP) specimens, and the steady-state hot box heat flux meter approach for HC3DP. The results demonstrate that HC3DP enables lower Thermal transmittance (U-value)s at lighter weight and faster printing speed, making it a promising avenue for further research. Additionally, the combination of HC3DP with aerogel is shown to create ultra-lightweight and thermally insulating 3D-printed facade elements. The potential of this new facade technology is also highlighted in comparison with established facade systems. All in all, the manuscript provides insights into the thermal performance of 3D-printed facades at different printing resolutions and emphasizes the importance of printing time and material consumption in determining the most promising 3D printing approach for lightweight and thermally insulating facades.