Lifestyle Disorders Research Articles

A comprehensive investigation into prebiotic influence of orange pectin on synergistic modulation of probiotic viability

Synbiotics are well accepted for their nutraceutical value and also in therapeutics for lifestyle disorders like diabetes, cardiovascular, neurological diseases and PCOS. Current manuscript presents the study of prebiotic potential of Pectin isolated from Nagpuri orange on the strains of probiotic bacteria like L. acidophilus, L. plantarum, B. bifidum, and B. lactis. In vitro and in vivo evaluation shows a significant increase in the L. acidophilus colonies as 2.12 ± 0.04 cfu/g followed by L. plantarum as 1.38 ± 0.03 cfu/g, B. lactis as 0.68 ± 0.04 cfu/g and B. bifidum as 0.48 ± 0.05 cfu/g using a modified MRS media. The highest cfu/g complemented the declined pH of cultured media to 6.05 ± 1.32 from near neutral pH. In vivo study using Sprague Dawley rats presented enhanced fecal colony count for L. acidophilus as 8.92 ± 0.04 cfu/g along with confirmation for microscopical characteristics of Gram-positive, rod-shaped, non-motile, non-sporulating bacteria showing catalase-negative, carbohydrate fermentation, lactic acid production, and positive arginine hydrolysis test. All blends of probiotic strains with Pectin as prebiotic material shown significant increase of biomass as compared to single probiotic administration. All results suggest the co-administration of Pectin with the L. acidophilus L. plantarum, B. bifidum, and B. lactis probiotic strains enhances in vitro and in vivo viability of these bacteria. More thorough quantitative analysis of the extract for in vivo parameters can help utilising it in the nutraceutical formulations as a prebiotic compound or as a synbiotic composition along with selected probiotic strains.

A CLINICAL COMPARATIVE STUDY TO ASSESS THE EFFECTIVENESS OF 'TRAYODASHANGGUGGULU','RASNADI KWATH' AND 'NIRGUNDIPATRAPINDASWEDA' IN THE MANAGEMENT OF ‘KATIGATAVATA ROGA’ (LUMBER SPONDYLOSIS)."

Now-a-days people are busy in their routine work and unaware to maintain their health. Consequently, they are being susceptible to various kinds of lifestyle disorders. The Disease Katigata vata Roga is one of the known crippling disorders claiming loss of daily activities of the affected person. To arrest the vatajvyadhi as like Asthigatavata Ayurveda has taken the fore most place in the management of like ‘Katigatavata Roga’. which can be correlated with Lumber spondylosis due to its clinical appearance. Due to wide spectrum of disease, much prevalence in the society and lack of effective medicament, the disease is being chosen for the study. The study was conducted in 20 clinically diagnosed patients of ‘Katigatavata Roga’.These patients are divided into two groups of 10 patients each . In this study10 Patients were treated by Trayodashangguggulu2 tab.(each tab. Of 500mg) three times in a day with lukewarm water and Rasnadi Kwath 50 ml two times in a day for 30 days and other 10 patients were treated with Nirgundipatra-Pindasweda with Rasna Dashamoola Taila for 40 minutes daily once a day for 15 days. From the observations and results it can be concluded that better results were obtained in all clinical manifestation of Katigata vataroga beside symptom of weakness on muscle on the basis of percentage relief.

UNDERSTANDING OF ASHTAMAHAVARJYAKARA BHAVAS -IN CURRENT CLINICAL PRACTICES

Ayurveda is an ancient system of medicine which is having widespread evidence of scientific practices to validate the science. It’s not just a medical system in the traditional sense of treating illnesses but also teaches us the way of life. The body has its own expressions which are silent signals or languages given to us to convey the message. These are generated by the smart system of our body as disease. Our minds should be ready to understand and respond as well. These expressions/factors are explained by our classics as “Ashtamahavarjyakara Bhavas”. Even though these factors are mainly highlighted concerning Shodhana or Panchakarma therapies also play a key role in present-day lifestyle disorders. According to World Health Organisation, 60% of factors influencing an individual’s health and quality of life are linked to lifestyle. The relationship between lifestyle and health should be highly considered. The reformation of this unhealthy lifestyle is the prevention factor for decreasing the rate of disease. The Majority of Diseases are caused by these factors forcefully initiating or by the continuous influence of these factors on the body. The magnitude of understanding these Bhavas has been discussed and hence present article is trying to explain its consequence in day-to-day practice and its effect on the present lifestyle.

An Ayurvedic methodology for managing PCOD - A Case Report

Polycystic ovarian disease (PCOD) is a heterogenous endocrine disorder characterized by ovarian cysts, anovulation, and hormonal fluctuations, impacting women’s health in various ways. PCOD has transformed into a lifestyle disorder due to sedentary habits, excessive consumption of fast food, and an unhealthy lifestyle. Predisposing risk factors such as genetics, neuroendocrine factors, lifestyle and environmental influences, as well as obesity, play significant roles in the development of PCOD. In Ayurveda, PCOD cannot be correlated to any one particular disease; it can be related to certain diseases like Vandhya, Nasthartava, Aratava Kshaya, Pushpaghni Jataharini, etc. and must be controlled according to the Dosha Dushya vitiation. In this present case study, a 21 year old female patient came with symptoms of scanty menses, acne over face and weight gain in the OPD of Kayachikitsa. The USG report reveals PCOD changes in both ovaries as both ovaries are bulky in size right ovary, vol = 18cc and left ovary, vol = 13.2cc with multiple peripherally arranged follicles with central echogenic stroma. The result was determined based on the relief of clinical symptoms and the findings from the ultrasound report. Therefore, in this case study, drugs such as Dashmool Kwath, Narikanti, Cystogrit diamond etc. was given which have Lekhaniya properties results into reducing the size of ovary and effectively alleviate Kapha Dosha and Ama, facilitating the treatment of Sroto-Dusti and removing obstructions caused by Apana Vayu, ultimately enhancing menstrual flow.

Effect of Vamana Karma and Panchkola Phanta in Hypothyroidism (Agnimandya)

Modernization leads to improper balance and disintegration of health and environment, body, mind and soul leading to lifestyle disorders. Hypothyroidism is one among the lifestyle and endocrinal disorder which is commonly encountered now days continuing to pose a major health issue. As it also responds to stress and stimuli the global incidence of hypothyroidism is more. This is leading to many lifestyle disorders and hormonal imbalance in our body. Hypothyroidism also known as underactive thyroid is a condition where the thyroid gland does not create enough thyroid hormones, which decreases the basal metabolic rate. Hypothyroidism may not cause noticeable symptoms in the early stage. It occurs about 7-8 times more frequently in females than males. The only modern treatment available is lifelong use of hormonal therapy (Levothyroxine sodium) but it has side effects on long term use. Thus, in order to prevent life long medication and side effects of synthetic drugs, using traditional and natural substance for treatment of hypothyroidism. In Ayurveda there is no direct reference of thyroid in Ayurveda classics but all the metabolic processes of the body are under the control of Agni. Ayurveda mentioned Shodhana Chikitsa, in Agnimandya dominancy of Kapha Dosha and Vamana Karma is best line of treatment for Kapha Dosha. Panchkola Phanta serves the purpose of Deepan and Pachana, thus eliminating the root cause of the disease and correcting the Agni and does the digestion of Ama. In Agnimandya, Panchkola Phanta is useful for Amapachana and to increase the Agni.

Management of Essential Hypertension (Ucharaktachap) - A Pilot Study

Hypertension is the most common lifestyle disorder today. Hypertension may be a chronic and sometimes asymptomatic medical condition during which systemic blood pressure is elevated beyond normal. Fewer than half of those with hypertension are conscious of their condition and lots of others are Modern treatment modalities are effective for the management of hypertension but pose human beings to their unwanted complications on their long-term use. The conventional antihypertensive drugs have many adverse effects & are not well tolerated which led to non-compliance, switching & discontinuation of treatment. There is no direct description of HTN in Ayurveda but based on its clinical presentation and similarity between pathogenesis factors for hypertension can be correlated with Raktadhatugata Vata (Vatpradhan) and it is considered as Tridoshaja Vyadhi. Treatment for hypertension in Ayurveda on the idea of Balancing all three Doshas. So Nidan Parivarajan, proper dietary habits, Yoga, Meditation along with Ayurvedic herbs can be beneficial for balancing the state of mind, maintaining as well as reducing blood pressure. Ayurveda has various classical formulations and single herbs having Hridya, Kaphahara, Vatahara, Balya, Raktaprasadana, etc. properties which are safe and cost-effective too. In present study Nitya Virechana Karma has been selected as Shodhana measure, to trump over offending Tridosas, as Virechana has also been equally effective in Rakta vitiation. In the present study Shamana remedy (Amritanagaradi Kashayam) has been selected taking in to view the aspect of the preventive, curative and also Dosha Pratyanic effect of Shamana Yoga drugs.

A mini-review on influence of physical exercise in remodeling the immune mechanism

Exercising on a regular basis has been associated with delay in onset of many lifestyle disorders and chronic conditions. Different types of exercise have varied effects on our innate immune cells, both positively and negatively. Low-intensity exercises like yoga or brisk walking, medium-intensity exercises like swimming or cycling, and long-term high-intensity exercises like playing sports like volleyball or working out in the gym are some examples. The immune system's function is impacted differently by exercise training depending on the type, duration, intensity, and other factors. Exercise training is a double-edged sword that helps the body's immune system by changing the immune cells' post-exercise reaction mechanisms. Regular physical exercise is one of the lifestyle adjustments aimed at minimizing morbidity and mortality associated with contemporary illnesses such as obesity, diabetes, cardiovascular disease, and cancer. Regular leisure exercise training is regarded to be beneficial, but extreme exercise, such as that performed by professional athletes, is thought to have possibly detrimental consequences. This review summarizes current information in the field of exercise-associated alterations of infection susceptibility and indicates knowledge gaps for further investigation. It highlights that long term effects of physical activity shows a positive association with longevity and exercise.

A CASE STUDY ON EFFECT OF MARMA CHIKITSA IN GRIDHRASI (SCIATICA)

Gridhrasi (sciatica) is pain dominant lifestyle disorder, in which the pain starts from Sphik Pradesha (back region) and radiates towards the foot. Marma Chikitsa is practice of healing certain vital point to stimulate the Prana, which is the body's life power. When a Marma point is touched, the body's biochemistry is altered, which can lead to drastic chemical alterations in an individual's constitution. When these are stimulated, the body produces specific neurochemicals that have a healing effect on both the body and the mind. In Gridhrasi, Marma Chikitsa was performed on Kshipra, Gulpha, Janu, Parsvasandhi, Katiktaruna, Nitamba, kukundara marma. Every marma mentioned above was stimulated and the frequency of stimulation was around 15 times in one sitting. Marma Chikitsa was performed for two weeks and two times in a day.

Impact of environment and ethnicity on prognosis in AF patients: does the 'where' matter more than the 'who'?

Abstract Background Atrial fibrillation (AF) is increasing worldwide and disparities are known between different geographically defined populations. However, populations are more and more multi-racial/multiethnic and less is known about the impact of geographical locations on various racial/ethnic populations. Purpose To study the influence of geographical location and race/ethnicity on the characteristics and the prognosis in AF patients. Methods From phase II/III of the GLORIA-AF registry, Asian and Caucasian patients from Western and Asian countries were included. The associations between geographical locations, race/ethnicity and a composite outcome composed of all-cause death, stroke and major bleeding were evaluated using Cox regression analyses. Results The study included 21,450 AF Caucasian and Asian patients from Western and Asian countries (mean±SD age 70.2±10; 44.3% female) with a median [IQR] follow-up of 3 years [2.3-3.1]. Among Caucasian patients, those living in Western countries (97.3%) were older, had less hypertension, congestive heart failure and coronary artery disease but more often lifestyle disorders (smoking, alcohol drinking) than those living in Asia (2.7%). Among Asian patients, those living in Western countries (2.6%) had more hypertension, diabetes mellitus, metabolic syndrome, coronary artery disease but less alcohol abuse than those living in Asia (2.6%). Regarding the composite outcome, Caucasian patients living in Asia had less adverse events than Asian patients living in Asia and Caucasian patients living in Western countries (adjusted hazard ratio on age, sex and CHA2DS2-VASc score (aHR): 0.53 (95% confidence interval (CI): 0.34-0.83), p=0.005) and aHR: 0.54 (95% CI: 0.35-0.83, p=0.005) respectively). Asian patients living in Asia had a better prognosis than Asian patients living in Western countries (aHR: 0.55 (95% CI: 0.35-0.85), p=0.007) and Caucasian patients living in Western countries when compared to Asian patients living in Western countries (aHR: 0.61 (95% CI: 0.40-0.94), p=0.025). Conclusion Geographical location has an impact on characteristics and prognosis of AF patients regardless of race/ethnicity. However, the gap in prognosis between Caucasian and Asian patients remains unchanged.Table 1.Baseline characteristics.Figure 1.Kaplan-Meier curves.

Diabetic nephropathy: Ayur‐nutri‐pharmaco approach

AbstractPrameha, described in Ayurveda, shares similarities with non‐communicable lifestyle disorder Diabetes Mellitus. It is associated with an array of complications, referred to as “Upadrava” which can manifest in various organ systems. Among the complications, diabetic nephropathy (DN) stands out as a critical concern due to its impact on kidney health. Ayurveda views the body as an interplay of Doshas, and diabetes‐related nephropathy is understood through the lens of “Prameha upadrava” which involves an imbalance of Doshas affecting kidney function. Ayurvedic treatment emphasizes personalized dietary adjustments, herbal remedies, lifestyle modifications, and mind‐body practices, wherein the Modern therapeutic approaches include receptor mediated targeting, stem cell therapies, and dietary management. The current review aims for better insights, amalgamating the ailments and divergence between Ayurvedic and pharmacological perspectives on pathophysiology and management of DN. A dedicated effort has been initiated to identify the specific edible botanical elements mentioned as Pramehaghna in the Ayurvedic compendium, Bhavaprakash nighantu. A comprehensive evaluation of botanical entities was performed for a deeper understanding of their enumerated properties. The data pave newer avenues toward multidimensional‐holistic approach to address the intricate complexities of DN leading to integrated approaches in Ayurveda, nutrition and pharmacology leading to better health and hygiene.

Ritu Shodhana - Way to Stay Healthy with special reference to Virechana

Ayurveda is a unique and ancient science of life which considers the Tridoshas vata, Pitta and Kapha as Tristhunas (pillars) of human body. The aim of Ayurveda is to maintain health of a healthy person and treating ailments of the diseased. Timely elimination of increased Doshas by purificatory measures during specified season is known as Ritu shodhana. Sharadiya Virechana i.e., purification therapy in autumn season is best for elimination of Prakupita (aggravated) Pitta dosha. The present review aims to summarize the benefits of Ritu shodhana with special reference to Virechana on health of a person. Materials and Methods: Literature search was carried out through search engines like PubMed, Web of Science and Google Scholar using keywords like ‘Ritu shodhana’, ‘Virechana’, ‘seasonal regimens’, ‘seasonal variations in India’,’ lifestyle disorders’. Classicals such as Bruhattrayis, Laghuttrayis were also reviewed. The relevant studies were identified and the findings summarized. Result and discussion- Ritu shodhana plays a key role in prevention of diseases. Among Panchakarmas virechana (purgation therapy) is one of the prime purificatory procedures for elimination of Pitta dosha. As the expulsion of Dosha occurs in normal route it is not complicated. Hence it has great promise and requires research in this area.

Effect of Abhyantara Snehapana and Vamana Karma in Patients with Normal and Abnormal to Lipid Profile

In the recent years, India and other developing countries are witnessing a rapid escalation in lifestyle disorders like diabetes, coronary artery disease, obesity, hypothyroidism, etc. The prime causative factor for all the lifestyle disorders is hyperlipidemia or dyslipidemia. Dyslipidemia is defined as a metabolic disorder that occurs due to abnormal blood lipid levels. This may lead to increase in the chances of atherosclerosis, heart attacks, stroke and other circulatory disorders. The abnormal lipid levels may include increase in triglycerides, VLDL, LDL and decrease in HDL. Vamana karma, a bio-purificatory emesis, being the major Panchakarma therapy has its greatest influence on almost all the lifestyle disorders. Lifestyle disorders aren’t possible without the involvement of Kapha dosha and Medho dhatu. Vamana is the first line of choice in the treatment of disorders caused by the aggravation of Kapha Dosha or Kapha associated with Pitta dosha. Vamana karma involves a pre-procedure called Snehapana, which include administration of high quantity of medicated lipids for a maximum period of seven days, followed by the bio-purificatory emesis or Vamana karma, a process of elimination of morbid Doshas from the oral route. Considering the high amounts of lipid usage in Snehapana, it becomes essential, to monitor its impact on lipid profile in patients undergoing Vamana karma for various etiologies. The present clinical study is of paramount importance as there were no previous studies on the impact of Sneha pana and Vamana in patients with both normal and abnormal lipid profiles. The statistical significance of results were quantitated by paired t test. Although Snehapana followed by Vamana, did not significantly alter levels of total cholesterol, and LDL, it did cause a significant reduction in triglycerides (p=0.0013) and VLDL (p=0.0038), improvement of HDL (P=0.02) in all the patients with abnormal lipid profile. However the values remained within the limit in patients with normal lipid parameters.

Multimodality Ayurveda Management of Beejashaya Granthi - A Lifestyle Disorder w.s.r to Polycystic Ovarian Syndrome

Polycystic ovarian syndrome is disorder that affects the whole life of a female, can begin in utero in genetically predisposed subjects, manifests clinically at puberty, and continues during the reproductive years. According to Ayurveda can be considered under Agni vaishamyajanya vikara and it can consider as Beeja kosha granthi. The basic concept of Ayurveda is Hetu-linga and Aushadha to make diagnosis and to cure this disorder. Excess Kapha dusthikara nidana overall causes Agnimandhya, then this causes Amotpatti (free radicals in body). Aam causes Artavavaha srotas rodha, these causes Dhatvagnimandhya and as a result Apachit ras dhatu and Uttarotara dhatu apachana leading to Meda dhatu dushti and Alpartava. Triphala and Guggulu act on Meda dhatu, Medohara in property. This proved to be act on adiponectin. 5-7% reduction in weight improves symptom of PCOS effectively. Pathya like Masha, Tila, Matsya, Kulatha, Udvisha, Dadhi, Sura, fruits helps in increasing the Agneyatwa of aartava dhatu. Organs involved in PCOS is ovary, adrenal gland, pancreas and pituitary gland, Agni of these organs are affected by modern stressful lifestyle. Ayurveda protocols of Dincharya, Ritucharya, Swastwrit, Acharya rasayan, Tri upsthambh- Aahara, Nidra and Bhrahmcharya, Shodhasha sanskara, Rajaswala paricharya, Garbhini paricharya, Sutika paricharya etc should be maintained for remaining disease free and to improve quality of life of a female, for making healthy female, healthy family and healthy nation.

Maintenance of Ocular Health by Ayurveda

There are five sense organs (Gyanendriya) in Ayurveda i.e., Eye, Ear, Nose, Tongue and Skin among them prime importance is given to eye. It says “Sarvendriyaanam Nayanam Pradhanam”. A faulty lifestyle has resulted in many eye disorders like Dry eye, Computer vision syndrome, Age related macular degeneration, Cataract, Diabetic retinopathy and many more which adversely effects quality of life. To avoid these lifestyle disorders, prevention of eye disorders and preservation of ocular health has become essential because good vision is necessary for social and intellectual development of humans. But unlikely the preventive aspects of eye health and diseases related to eye has not been given due importance in our day-to-day life. For preventing these eye disorders and for maintaining eye health much more has been described in Ayurvedic texts in the form of Dincharya (Daily regimen), Ritucharya, Sadvritta, Swasthavritta and Chakshyusya Rasayana. Many tested procedures like Anjana (Collyrium), Netraprakshalana (Eye wash), Snana (Bath), Padabhyanga (Foot massage with oil) are highly effective daily procedures for the prevention of eye disorders and maintenance of good eye health. Various Yogasana, Pranayama, Neti and Trataka are also considered beneficial for the eye health. The aim of this article is to spread awareness among society about the maintenance of eye health and prevention of eye disorders.

The nutrition and therapeutic potential of millets: an updated narrative review.

Millets are ancient small grains grown in arid and semiarid regions of the world. They are staple food for many people in Asia and Africa. They are abundant sources of minerals and vitamins, giving them the name Nutricereals. Moreover, millets contain valuable phytochemicals that impart therapeutic properties for various disorders and diseases, thus giving them nutraceutical value. A wide array of biochemical compounds are present in the plant parts as well as the grains. In the oldest texts of medicine in India and China, millets are mentioned for use for their medicinal value. There has been expanding interest and emerging facts about millets and their therapeutic uses. Ample evidence shows that consumption of millets amounts to correction of life style and metabolic disorders. Therapeutic properties of millets can be viewed in two ways, supplementary nutrition through minerals and vitamins, and therapeutic value through the presence of phytochemicals and specialty compounds that include flavonoids, phenolics, anthocyanidins and others that have antioxidant potential. Millets are gluten free, have low glycemic index and the phytochemicals aid in correction of lifestyle disorders and prevention of ailments like carcinogenesis. Supplementary benefits include treatment of anemia and calcium deficiency especially for pregnant women and young children. With the improvements in analytical methods for detection of various compounds, it is possible to identify the compound-specific genotypes in millets that can cater to the pharmacy industry. End-use specific genotypes can be bred to meet the demand. Millets being climate resilient, can contribute to a healthier life and better world through economic usage of natural resources.

Critical appraisal of Millets - A Conceptual Study

Recently the millets have been recognised with their enormous potential and they are renovate as Nutri-cereals (shree anna). Millets are good source of protein, vitamins, and minerals like phosphorus, calcium, magnesium, iron etc. As millets are loaded with phytochemicals, they help in management of various life style disorders like cardiovascular disease, obesity, diabetes mellitus, cancer. Millets are one of the oldest staples for various civilisation across the continents. In Ayurveda literature they are explained under the Dhanya Varga as Trindhanya, Kudhanya and Kshudradhanya. General properties of millets are Ushna Veerya, Kashaya and Madhura Rasa, Katu Vipaka, Laghu and Ruksha Guna. But beyond these, some specific properties have also been mentioned in detail in Ayurveda Classics. In Ayurveda literature millets have been described as Pathya-Apathya in various diseases. Present paper encompasses various aspect of Millets described in Ayurveda and contemporary science so that the importance of millets is known to each and every person.

Unlocking Fertility - with administration of Lekhaniya Mahakashaya in Pushpaghani Jataharini w.s.r. to PCOD

Children are a gift from the Lord; the fruit of the womb is a divine reward. Average Reproductive Age is 14-49 yrs. This age group have number of conditions related to menstrual cycle, such as Menorrhagia, Dysmenorrhea, Irregular menses, PCOD, endometriosis, etc. According to WHO - PCOD is a lifestyle disorder which is a common hormonal condition that affects women of reproductive age. It usually starts during adolescence, but symptoms may fluctuate over time. PCOD can cause hormonal imbalances, irregular periods, excess androgen levels and cysts in the ovaries, absence of menstruation, excessive hair growth (face, body, including back, belly and chest), acne, weight gain, hair loss, skin darkening (in neck and groin). Irregular periods, usually with a lack of ovulation, can lead infertility. PCOD is a leading cause of infertility. PCOD can lead to anovulation where ovaries stop releasing eggs. PCOD is a common condition that causes 70% of anovulation cases. PCOD causes the excessive production of androgens, which cause the follicles in your ovaries to remain small instead of maturing and growing as they have to prepare for ovulation. In Ayurveda on the basis of symptoms Pushpaghani Jataharini can be correlated with PCOD. PCOD is a chronic condition and cannot be cured. However, some symptoms can be improved through lifestyle changes and medications. In order to treat PCOD the changes in the life style and the administrations of Ausadhies like Lekhaniya Mahakashaya (Musta, Kustha, Haridra, Daruharidra, Vacha, Ativisha, Katurohini, Chitrak, Chirbilva).

An Ayurvedic appraisal on Ahiputana w.s.r. to Diaper Rash - A Case Study

Many disorders during Balyavastha are caused due to vigilant caring of parents and Ahiputana is one such commonly seen condition. The calculated risk of developing diaper rash is 1 in 4 infant and the peak incidence is found in between 9 to 12 months. Ahiputana is a Kapha Rakta Pradhana Kshudraroga, caused due to unhygienic conditions such as improper cleaning after defecation and urination, presenting with Kandu and oozing blisters at perianal region, forming Vrana. Diaper rash is similar condition in contemporary science reported due to improper toilet training, hygiene and child rearing practices in day to day life. Soiled or wet laden diapers that are left for too long, results in sore and scaly rashes due to Candida albicans. This life style disorder occurring at infancy has cure through Ayurveda via Bahyaparimarjana and Antahparimarjana Chikitsa as explained in different classics. Different Lepa prayoga has extensive result over the same. Zinc oxide is used commonly in treating diaper rashes in contemporary science. Many formulations mentioned in classics yields better effect over diaper rash. The present study attempts to highlight the concept and treatment of Ahiputana in Bala caused due to life style hazard.

“Vitaction” deficiency: a possible root cause for multiple lifestyle disorders including Alzheimer’s disease

Behavioural environment and behavioural responses of an individual are known to affect multiple aspects of physiology including neuroendocrine and growth factor signalling, angiogenesis, stem cell dynamics, tissue homeostasis, and maintenance. Despite substantial evidence, the role of behaviour-physiology interface in human health and disease remains underappreciated. The hypothesis proposed here suggests that deficiencies of certain behaviours that have evolved to become essential or “vitactions” can potentially trigger multiple health problems. Altered growth factor expression because of vitaction deficiencies affects angiogenesis and vascular function, neuronal maintenance, transport of glucose and other nutrients to the brain, mitochondrial function, oxidative stress, inflammation, and protein aggregation dynamics all implicated in Alzheimer’s disease (AD). Exercise is already known to be effective in prevention of AD. The hypothesis suggests that it is the behavioural component of exercise over mechanical activity and calorie burning that has crucial effects on brain health through multiple signalling pathways. Similar to vitamin deficiencies, where supplying the deficient vitamin is the only effective solution, for vitaction deficiencies supplying the deficient behavioural stimuli through behaviourally enriched exercise can be the most effective remedy.

Ayurvedic Treatment Modalities of Diabetic Peripheral Neuropathy

Diabetic peripheral neuropathy is the damage of the nerves due to the uncontrolled diabetes. It can affect any of the neurons can affect any of the neurons. Diabetic distal symmetric sensory and sensorimotor polyneuropathy is the most prevalent type of diabetic neuropathy. The symptoms appear as sensory loss, first in the toes and progressively moving up the legs, fingers, and arms over time. Tingling sensation, Burning sensation, Deep aching pain are other related symptoms. A patient age 54 years with diabetes for past 15 years, hypertension, dyslipidemia, complains of burning sensation of both feet (right>left), numbness, pricking pain, unsteadiness while walking, brownish red discolouration of both lower limbs. The symptoms were gradual in onset. Nerve Conduction Study showed axonal type of motor and sensory affecting peroneal nerve neuropathy. He admitted in Vaidyaratnam Ayurveda College Hospital, done Vibrotherm Neuropathy Analyzer and revealed small and large fibre neuropathy with severe loss of sensations. The main intention of the study is to improve the quality of life of the patient by reducing the symptoms that is disturbing his day today routine. Patient given with anti diabetic Ayurvedic formulations internally. Externally Rookshana, Vatahara, Brimhana treatments were done. After the treatment, Michigan neuropathy screening instrument, diabetic Neuropathy symptom score, Toronto clinical scoring system score were reduced. Neuropathy Analyzer showed mild to moderate loss of sensation. By adopting Prameha hara chikitsa coupled with Vata vyadhihara chikitsa, complications of diabetes can be managed. It is important to focus on diet and regimen since diabetes is a lifestyle disorder and, in ayurveda it is considered as an Anushangi Vyadhi.