Life In Colorectal Cancer Patients Research Articles

069. Evaluation Quality of Life in Colorectal Cancer Patients After Rectal Resection with Ileostomy

Background: Colorectal cancer where each person has a risk of 1:23 of colorectal and increases according to lifestyle colorectal is the 3rd highest cancer with a prediction of 3.2 billion new cases by 2040. Surgery in the form of resection with ileostomy is performed in up to 95% of cases of colorectal cancer. Quality of life after surgery with ileostomy can be evaluation with EORTC QLQ-C30 and CR29. Methods: Retrospective method with total sampling for 1 year 2023-2024 conducted at Sardjito Hospital, patient data obtained from medical records, questionnaire evaluation using interviews with inclusion criteria. Results: There were first complaints the patient in the form of 54% of bloody stools with the time of complaints range 6 months to 1 year. While 60% of patients came from hospital referrals using government health insurance. The age range is 58 years and dominated by women with BMI status of underweight patients and low education. Tumor borders at 5-10 cm from the anal verse with 75% performed adjuvant chemotherapy and 87% performed colonoscopy. Stage was predominantly stage 3 and adenocarcinoma cancer type up to 65%. EORTC QLQ-C30 and EORTC QLQ-CR29 evaluation results showed differences in emotional functioning at 6 months (p0.04) and decreased body image at 3 months postoperatively (p0.02). There were differences in global quality of life in parts but none in general (p>0.05). Conclusion: Overall, patients experience changes in emotional function at 6 months post and body image at 3 months postoperatively. overall global quality of life scores are no significant.

Application of Nanoparticles in the Diagnosis and Treatment of Colorectal Cancer.

Colorectal cancer is a common malignant tumor with high morbidity and mortality rates, imposing a huge burden on both patients and the healthcare system. Traditional treatments such as surgery, chemotherapy and radiotherapy have limitations, so finding more effective diagnostic and therapeutic tools is critical to improving the survival and quality of life of colorectal cancer patients. While current tumor targeting research mainly focuses on exploring the function and mechanism of molecular targets and screening for excellent drug targets, it is crucial to test the efficacy and mechanism of tumor cell therapy that targets these molecular targets. Selecting the appropriate drug carrier is a key step in effectively targeting tumor cells. In recent years, nanoparticles have gained significant interest as gene carriers in the field of colorectal cancer diagnosis and treatment due to their low toxicity and high protective properties. Nanoparticles, synthesized from natural or polymeric materials, are NM-sized particles that offer advantages such as low toxicity, slow release, and protection of target genes during delivery. By modifying nanoparticles, they can be targeted towards specific cells for efficient and safe targeting of tumor cells. Numerous studies have demonstrated the safety, efficiency, and specificity of nanoparticles in targeting tumor cells, making them a promising gene carrier for experimental and clinical studies. This paper aims to review the current application of nanoparticles in colorectal cancer diagnosis and treatment to provide insights for targeted therapy for colorectal cancer while also highlighting future prospects for nanoparticle development.

Association between Physical Activity and Quality of Life in Colorectal Cancer Patients with Postoperative Defecatory Dysfunction: A Preliminary Survey.

In this study, we aimed to explore the association between physical activity (PA) and quality of life (QoL) in colorectal cancer (CRC) patients with postoperative defecatory dysfunction. A survey using the European Organization for Research and Treatment of Cancer QLQ-30 and QLQ-29 was conducted among 62 adult outpatients with CRC at two cancer hospitals in Japan. PA and sedentary behavior were evaluated using the Global Physical Activity Questionnaire. Multiple regression analysis was performed, incorporating the QoL as the outcome, with the total PA and its three domains (occupational, transportation, and recreational) and sedentary time as exposures, while controlling for age, sex, and tumor location. The analyses revealed that patients engaged in PA ≥ 150 min/week (67.4 points; 95% confidence interval [CI]: 21.1, 113.8) and recreational PA ≥ 30 min/week (56.0 points; 95% CI: 2.3, 109.7) had significantly higher function scores. Conversely, sedentary time >8 h/day or occupational PA duration ≥30 min/week was associated with poor symptom and function scores. These findings highlight the importance of promoting recreational PA and reducing sedentary behavior to maintain and improve the QoL in CRC patients with defecatory dysfunction.

Quality of Life of Colorectal Cancer Patients: A Literary Review

Colorectal cancer (CRC) is a major contributor to global cancer cases and deaths, making it a significant public health concern. As the number of CRC survivors continues to rise, understanding the impact of CRC and its treatment on their quality of life (QoL) has become increasingly important. The determinants of QoL in CRC patients are multifaceted and include physical health, physical fitness, physical activity, healthy eating, psychological health, social support, the availability of high-quality medical care, and QoL at the end of life. These factors interact to shape the overall well-being of CRC survivors. To enhance the QoL of CRC patients, a comprehensive approach is needed. This includes tailoring treatments to individual patient characteristics, providing psychological support and symptom management, promoting post-treatment rehabilitation, organizing support groups, emphasizing early detection, and effectively managing CRC-related symptoms. Addressing these aspects can significantly improve the QOL and well-being of CRC survivors, helping them adapt to life after treatment and thrive in the face of the challenges they may encounter

Correlation analysis of interstitial maturity and prognosis of colorectal cancer: Meta-analysis.

To investigate the relationship between interstitial maturity and prognosis of colorectal cancer. To examine the correlation between interstitial maturity and the prognosis of colorectal cancer. The paper database PubMed, EMBASE, Cochranelibrary, Springerlink, CNKI, and Wanfang database were searched until December 2023. "tumor stroma maturity" "desmoplastic stroma reaction" "desmoplastic reaction" "stroma reaction" "degree of stroma reaction "" stroma classification" "stroma density" "colorectal cancer" "colon cancer" "rectal cancer" "prognosis" were searched for the search terms. Two system assessors independently screened the literature quality according to the inclusion exclusion criteria, Quality evaluation and data extraction were performed for the included literatures, and meta-analysis was performed for randomized control trials included at using Review Manager 5.2 software. Finally, data of 9849 patients with colorectal cancer from 19 cosets in 15 literatures were included, including 4339 patients with mature type (control group), 3048 patients with intermediate type (intermediate group) and 2456 patients with immature type (immature group). The results of meta-analysis showed: Relapse-free survival [hazard ratio (HR) = 2.66, 95% confidence interval (CI): 2.30-3.08; P < 0.00001], disease-free survival (HR = 3.68, 95%CI: 2.33-5.81; P < 0.00001) and overall survival (HR = 1.70, 95%CI: 1.53-1.87; P < 0.00001) were significantly lower than those in mature group (control group); relapse-free survival (HR = 1.36, 95%CI: 1.17-1.59; P < 0.0001) and disease-free survival rate (HR = 1.85, 95%CI: 1.53-2.24; P < 0.0001) was significantly lower than the mature group (control group). There is the correlation between tumor interstitial maturity and survival prognosis of colorectal cancer, and different degrees of tumor interstitial maturity have a certain impact on the quality of life of colorectal cancer patients.

Spiritual Support for Colorectal Cancer Patients to Improve Their Quality of Life: A Literature Review

Intoduction: Spiritual assistance is an important action for colorectal cancer patients to improve their quality of life. Methods: The database search method uses systematic and comprehensive electronic data from four databases, namely: Scopus, CINAHL, PubMed, and Proquest and Manual. Search terms "OR", spirituality "AND", spiritual support "AND" quality of life. Article search using the PICO model (population, intervention, comparison, outcome). Data selection is carried out by determining inclusion and exclusion criteria, carried out after identifying the problem, the group to be studied, the intervention to be provided, and the results to be measured. A total of 25 articles were discoered. Results: The spiritual interventions provided are mindfulness, meditation, music therapy and telephone counseling. This is intended to motivate patients to be more enthusiastic about undergoing treatment and improve their quality of life. Conclusions: Spiritual support influences the quality of life of colorectal cancer patients, namely providing a sense of peace and the desire to continue undergoing the treatment process, with routine daily activities as evidence of improving the patient's quality of life.

Pemberian Edukasi Berbasis Multimedia terhadap Kemampuan Perawatan Diri Pasien Kanker Kolorectal dengan Stoma

This study aims to determine the effectiveness of providing multimedia-based education on self-care of colorectal cancer patients with stomas. The research method used was a systematic review on four databases, namely Pubmed, Science Direct, ProQuest and Scopus with the keywords "colorectal cancer" OR "patient with stoma", AND "stoma education" OR "stoma management education", AND "self care", OR "self management" with the inclusion criteria of colorectal cancer patients, age&gt; 18 years, from 2013 to 2023. The number of initial search articles was 4377 articles with 8 articles used. The results of the study obtained 8 articles which were then analyzed. In conclusion, the use of multimedia with OMRE, MELP, video (DVD), audiovisual, telehealth and mobile health applications to provide stoma care education can have an effective effect in increasing knowledge and self-care. In addition, it also has an effect on improving psychosocial adaptation and quality of life in colorectal cancer patients with stomas. Keywords: Education, Stoma Care, Multimedia, Self Care

Quality of life of colorectal cancer patients: A cross-sectional study, Alexandria, Egypt

Quality of life of colorectal cancer patients: A cross-sectional study, Alexandria, Egypt

Symptom Experience and Quality of Life in Colorectal Cancer Patients Undergoing Chemotherapy – A Secondary Publication

Objective: To evaluate symptom experience and quality of life (QoL) and to identify the predictors of QoL among colorectal cancer patients undergoing chemotherapy. Methods: A cross-sectional study was conducted on 107 colorectal cancer patients at a university-affiliated hospital between June 1 and July 30, 2021. Functional Assessment of Cancer Therapy-Colorectal (FACT-C) and Memorial Symptom Assessment Scale-Short Form (MSAS-SF) were used to assess symptom experience and QoL of these patients. Data were analyzed using Pearson’s correlation, t-test, ANOVA, and hierarchical multiple regression. Results: The mean QoL score for colorectal cancer patients was 88.78 ± 20.08. The most frequently experienced physical and psychological symptoms were numbness/tingling and worrying. Physical and psychological symptoms have a significant negative association with QoL. Perceived economic status was significantly associated with QoL in patients’ general characteristics. The regression analyses showed that high psychological symptoms (β = -0.63, P &lt; 0.001), middle perceived economic status (β = -0.22, P = 0.009), and low perceived economic status (β = -0.36, P &lt; 0.001) were statistically significant in predicting patients’ low QoL. Conclusion: Symptom experience and QoL are essential variables that should be acknowledged when delivering health care to colorectal cancer patients. More attention to the reduction and comprehensive symptom management of psychological distress could improve QoL among colorectal cancer patients.

Effect of a telephone-based perioperative nurse-led counselling programme on unmet needs, quality of life and sexual function in colorectal cancer patients: A non-randomised quasi-experimental study

PurposeTo investigate the effect of perioperative nurse-led counselling intervention on unmet needs, sexual function and quality of life in colorectal cancer patients. MethodThis quasi-experimental study included 82 patients who underwent colorectal cancer surgery (control n = 45, intervention n = 37). The telephone-based perioperative nurse-led counselling intervention, which contained implementation, follow-up, and assessment, was applied to start from pre-surgery to post-surgery 3rd month. Data were collected with the Unmet Needs of Cancer Survivors Scale, European Organisation for Treatment and Research of Cancer Quality of Life Scale-30, Colorectal-29, Female Sexual Function Index, and International Index of Erectile Function pre- and post-surgery 3rd-6th months. The control data was collected before the pandemic, and the intervention group throughout the pandemic. The Mann-Whitney-U, Wilcoxon rank test was used. ResultsCompared to the control group, intervention group patients reported lower unmet and total needs scores (p = 0.000); higher quality of life (p = 0.000), physical, emotional (p = 0.000), role (p = 0.001), and social functioning scores (p = 0.002); lower fatigue (p = 0.000), constipation (p = 0.034), pain (p = 0.018), nausea-vomiting (p = 0.004), and insomnia scores (p = 0.003); and higher body image, anxiety (p = 0.000) and weight scores (p = 0.003), lower urinary frequency buttock pain (p = 0.000), dysuria (p = 0.001), abdominal pain (p = 0.001), fluctuance (p = 0.000), stool frequency (p = 0.002), and faecal incontinence (p = 0.006) scores at the sixth month (p < 0.05). There were no statistically significant differences between male and female sexual function scores (p > 0.05). ConclusionsPerioperative nurse-led counselling reduced unmet needs and increased the overall quality of life by decreasing symptom levels but did not affect sexual health outcomes in patients with colorectal cancer surgery.

Discharge teaching quality positively predicts quality of life in colorectal cancer patients with temporary enterostomy: The mediating role of readiness for hospital discharge and stoma self-efficacy.

This study aimed to examine the mediating role of readiness for hospital discharge (RHD) and stoma self-efficacy (SSE) in the relationship between quality of discharge teaching (QDT) and health-related quality of life (HRQOL) in colorectal cancer patients with temporary enterostomy, and the gender difference of mediating effect. It is not clear how RHD, QDT, SSE and HRQOL interact in colorectal cancer patients with temporary enterostomy. This was a prospective follow-up survey. 221 colorectal cancer patients with temporary enterostomy were conveniently recruited from a general hospital in Southeast China. The Quality of Discharge Teaching Scale, Readiness for Hospital Discharge Scale, Stoma Self-Efficacy Scale, and Stoma Quality of Life Scale were used to collect data. Pearson's correlation and structural equation models were used to analyze the data. SPSS 26.0 and Amos 28.0 software were used for analysis the collected data. Regarding the relationship of QDT and HRQOL, only QDT-T had a direct effect among colorectal cancer patients with stomas (b = 0.233, P<0.001, percentile 95% CI = [0.145, 0.314]). However, both QDT-T and QDT-R can predict HRQOL indirectly through three paths: (1) the mediating role of SSE (b = 0.050, P = 0.009, percentile 95% CI = [0.013, 0.098]; b = 0.077, P = 0.008, percentile 95% CI = [0.021, 0.164]), (2) the mediating role of RHD (b = 0.044, P = 0.004, percentile 95% CI = [0.014, 0.085]; b = 0.044, P = 0.005, percentile 95% CI = [0.010, 0.102]), and (3) the chain mediating role of SSE and RHD (b = 0.030, P = 0.003, percentile 95% CI = [0.011, 0.059]; b = 0.047, P = 0.003, percentile 95% CI = [0.015, 0.103]). The similar chain mediating effect in male stoma patients was also found (b = 0.041, P = 0.002, percentile 95% CI = [0.016, 0.080]; b = 0.046, P = 0.004, percentile 95% CI = [0.011, 0.114]). Stoma self-efficacy and readiness for hospital discharge played important intermediary roles in the relationship between quality of discharge teaching and health-related quality of life in colorectal cancer patients with stomas. Health care providers can design SSE-enhancing and RHD-enhancing discharge planning for colorectal cancer patients with temporary enterostomies.

The Influence of Uncertainty in Illness and Coping on Quality of Life in Colorectal Cancer Patients Receiving Chemotherapy

The Influence of Uncertainty in Illness and Coping on Quality of Life in Colorectal Cancer Patients Receiving Chemotherapy

Reliability and validity of the Turkish version of the New Cleveland Clinic Colorectal Cancer Quality of Life Questionnaire.

This study aims to adapt and validate the Cleveland Clinic Colorectal Cancer Quality of Life Questionnaire (CCF-CaQL) in Turkish, addressing the significant need for reliable, language-specific QoL measures for colorectal cancer (CRC) in Turkiye. This effort fills a critical gap in CRC patient care, enhancing both patient-provider communication and disease-specific QoL assessment. The CCF-CaQL was translated into Turkish, verified for accuracy, and reviewed for clarity and relevance. Eligible patients who underwent colorectal surgery for cancer between July 2021 and July 2022 from six hospitals completed the CCF-CaQL and SF-36 questionnaires. For analysis, confirmatory factor analysis using Smart PLS 4 and descriptive statistics were employed. The questionnaire's reliability and validity were assessed using Cronbach alpha, composite reliability, and the heterotrait-monotrait (HTMT) ratio, along with multicollinearity checks and factor loadings. Nonparametric resampling was used for precise error and confidence interval calculations, and the Spearman coefficient and split-half method were applied for reliability testing. In the study involving 244 colorectal cancer patients, confirmatory factor analysis of the CCF-CaQL indicated effective item performance, with one item removed due to lower factor loading. The questionnaire exhibited high internal consistency, evidenced by a Cronbach alpha value of 0.909. Convergent validity was strong, with all average variance extracted (AVE) values exceeding 0.4. Discriminant validity was confirmed with HTMT coefficients below 0.9, and no significant multicollinearity issues were observed (VIF values < 10). Parallel testing with the SF-36 scale demonstrated moderate to very strong correlations, affirming the CCF-CaQL's comparability in measuring quality of life. The Turkish version of the CCF-CaQL was validated for assessing quality of life in colorectal cancer patients. This validation confirms its reliability and cultural appropriateness for use in Turkiye. The disease-specific nature of the CCF-CaQL makes it a useful tool in clinical and research settings, enhancing patient care by accurately monitoring treatment effects and interventions in the Turkish colorectal cancer patient population.

Hierarchical Personalized Nutrition and Exercise Interventions Based on the ADOPT Model Effectively Improve the Health of Patients with Colorectal Cancer

This study aimed to assess the efficacy of hierarchical personalized nutrition and exercise interventions based on the Attitude-Definition-Open-mindedness-Plan-Trial model in improving gastrointestinal function, nutritional status, muscle function, and quality of life in patients with colorectal cancer. A retrospective analysis compared the outcomes of patients with rectal cancer receiving standard interventions (control group) and those receiving hierarchical personalized nutrition and exercise interventions based on the Attitude-Definition-Open-mindedness-Plan-Trial model (treatment group). The findings indicate that before the interventions, the two groups observed no statistically significant differences between the serum concentrations of nutritional markers (hemoglobin, transferrin, albumin, and prealbumin). However, these markers exhibited significantly higher levels in the treatment group than in the control group. Furthermore, the treatment group had higher SF-36 scores, shorter recovery times for gastrointestinal function, shorter hospital stays, and lower rates of complications. There were no significant differences in muscle co-contraction rates and mass between the two groups before the intervention. The treatment group had lower co-contraction rates and higher muscle mass post-intervention than the control group. In conclusion, hierarchical personalized nutrition and exercise interventions based on the Attitude-Definition-Open-mindedness-Plan-Trial model effectively improve gastrointestinal function, nutritional status, muscle function, and quality of life in colorectal cancer patients.

Efficacy of a self-management program on quality of life in colorectal cancer patients: A randomized controlled trial

PurposeTo test the efficacy of a self-management program based on acceptance and commitment therapy on quality of life, emotional distress, fatigue, physical activity, and fruit and vegetable intake in patients with colorectal cancer. MethodsThe study was a randomized controlled trial. A sample of 156 patients with colorectal cancer (stage I–III) was recruited by convenience sampling and participants were allocated randomly assigned to control or intervention groups. The intervention included a colorectal cancer self-management information booklet, two personal skills training sessions, and 12 follow-up telephone calls. The control group received health education leaflets. Outcome variables were assessed in both groups at baseline and every two months thereafter during the six-month follow-up period. ResultThe mean age of participants was 62 years (range: 30–89 years). Generalized estimation equations analyses revealed significant differences over time in changes in anxiety (β = −2.22, p = 0.001), depression (β = −1.48, p = 0.033), fatigue (β = 4.46, p = 0.001), physical and functional measures (β = 6.16, p = 0.005), and colorectal-cancer–specific quality of life (β = 7.45, p = 0.012). However, there were no significant differences in changes in physical activity or fruit and vegetable intake over time. ConclusionThe self-management skills provided by oncology nurses, including symptom management, psychological adjustment, and relaxation exercises, help colorectal cancer patients to overcome the challenges of cancer survivorship, accelerate their recovery, and improve their quality of life. The trial numberNCT03853278 registered on ClinicalTrials.gov.

Effect of low anterior resection syndrome on quality of life in colorectal cancer patients: A retrospective observational study

Postcholecystectomy bile duct injury (BDI) remains a devastating iatrogenic complication that adversely impacts the quality of life with high healthcare costs. Despite a decrease in the incidence of laparoscopic cholecystectomy-related BDI, the absolute number remains high as cholecystectomy is a commonly performed surgical procedure. Open Roux-en-Y hepaticojejunostomy with meticulous surgical technique remains the gold standard surgical procedure with excellent long-term results in most patients. As with many hepatobiliary disorders, a minimally invasive approach has been recently explored to minimize access-related complications and improve postoperative recovery. Since patients with gallstone disease are often admitted for a minimally invasive cholecystectomy, laparoscopic and robotic approaches for repairing postcholecystectomy biliary stricture are attractive. While recent series have shown the feasibility and safety of minimally invasive post-cholecystectomy biliary stricture management, most are retrospective analyses with small sample sizes. Also, long-term follow-up is available only in a limited number of studies. The principles and technique of minimally invasive repair resemble open repair except for the extent of adhesiolysis and the suturing technique with continuous sutures commonly used in minimally invasive approaches. The robotic approach overcomes key limitations of laparoscopic surgery and has the potential to become the preferred minimally invasive approach for the repair of postcholecystectomy biliary stricture. Despite increasing use, lack of prospective studies and selection bias with available evidence precludes definitive conclusions regarding minimally invasive surgery for managing postcholecystectomy biliary stricture. High-volume prospective studies are required to confirm the initial promising outcomes with minimally invasive surgery.

Edukasi terhadap Self Efficacy dan Kualitas Hidup Pasien Kanker Kolorektal yang Menjalani Kemoterapi

This study aims to identify the effect of education on self-efficacy and quality of life in colorectal cancer patients undergoing chemotherapy. The method used is quantitative, using a quasi-experimental design with a nonequivalent control group pre-posttest-only design method with a sample size of 56 people, using the GSE (General Self Efficacy) questionnaire instrument and the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-C30 (EORTC QLQ). -C30). The results of the research show that education affects the self-efficacy of colorectal cancer patients undergoing chemotherapy with a p-value &lt;0.05, and education affects the quality of life of colorectal cancer patients undergoing chemotherapy with a p-value &lt;0.05. The conclusion is that educational interventions positively increase self-efficacy and quality of life in colorectal cancer patients undergoing chemotherapy.&#x0D; &#x0D; Keywords: Education, Colorectal Cancer, Quality of Life, Self Efficacy

Meta-analysis of the effect of laparoscopic surgery and open surgery on long-term quality of life in patients with colorectal cancer.

To compare the effect of laparoscopic surgery and open surgery on the quality of life of patients with colorectal cancer (CRC) in the growth period after the operation, and to provide a reference for surgical treatment decisions of patients with CRC. PubMed/MEDLINE, EMBASE, Web of Science, and Cochrane databases were searched through May 7, 2022 for clinical studies comparing the postoperative quality of life in CRC patients who underwent laparoscopic surgery with those who underwent open surgery. Data were extracted from eligible studies following rigorous quality review. All studies included patient numbers, surgery type, follow-up length, and quality of life scores. A total of 6 studies were included, resulting in significantly better physical functioning scores with laparoscopic versus open surgery. (Standardized mean difference = 0.45; 95% CI (0.15, 0.75), P = .003). However, in general health, social functioning, bodily pain, vitality, quality of life index, Global Quality Scale, physical component summary and mental component summary, there was no telling difference between the 2 surgical therapies. Compared with open surgery, laparoscopic surgery has weak advantages. There was no noteworthy difference in the long-term quality of life between the 2 surgical treatments for CRC patients. Whether laparoscopic surgery can bring more improvement to the quality of life of patients with CRC needs more high-quality clinical randomized studies to verify.

A quality control circle process to improve enteral nutrition feeding support in discharged patients with colorectal cancer.

Correct usage and maintenance of the enteral nutrition feeding pump system is always a challenge in nutrition support for patients with colorectal cancer (CRC). However, there are few studies on the sustained accuracy improvement of the enteral nutrition feeding system in discharged CRC patients. Here, we established a seven-month quality control circle (QCC) activity with the theme of improving the performance of home enteral feeding pumps (EFP) and examined the effect of QCC activity on the nutritional state and quality of life in discharged CRC patients. We enrolled 100 discharged CRC patients treated with home enteral nutrition from Zhejiang Cancer Hospital between March 2020 and December 2021. The patients were randomly split into two research groups: one participated in the QCC activity (n = 50) and the other did not (n = 50). QCC analysis indicated that the top 3 causes of EFP inaccurate usage are the simple and boring contents of training, various types of pumps, no examination rules, and lack of management. Furthermore, both intra- and inter-group comparisons showed that QCC significantly improved the patients' pass rate of nutrition pump operation from 52 to 70% after 1-month of activity, which gradually improved and got the highest (90%) after 3 months (p < 0.05). Interestingly, the established QCC activity significantly increased the patient-generated subjective global assessment (PG-SGA) and Barthel index (BI) scores, body fat mass (BFM) and superior longitudinal muscle (SLM) by intra- and inter-group comparisons. In this study, we clarified the main causes of inaccurate EFP usage and established a QCC process to improve the pass rate of EFP usage. It finally leads to the improvement of nutritional state and quality of life in CRC patients.

The Effect of Reflexology on Quality of Life in Colorectal Cancer Patients Suffering Chemotherapy-induced Neuropathy: A Randomized and Controlled Trial

The Effect of Reflexology on Quality of Life in Colorectal Cancer Patients Suffering Chemotherapy-induced Neuropathy: A Randomized and Controlled Trial