Life In Breast Cancer Patients Research Articles

Indian Medicine Can Improve Quality of Life in Breast Cancer Patients: Case Studies

The present study was evaluated the QoL of breast cancer patients who were taking Body Revival, an Indian polyherbal medicine. A case study was conducted among 5 breast cancer patients, who were voluntarily treated with Body Revival for ≥6 months. The average age of 5 breast cancer patients was 48.6 yrs (range 35-64 yrs), out of them 3 suffered in Stage II and 2 in Stage IV with metastasis. 3 patients undergo surgery, 4 under chemotherapy treatment and 1 did not received any chemotherapy or surgery. All of them used Body Revival (average 13.2 months). A structured and validated interview schedule was used to gather data from cancer patients. The QOL of all the patient symptoms was significantly improved (p<0.001) with Body Revival supplementation. It improved both the psychological and physical domains of day-to-day life, either by attenuating the adverse events of regular treatments for cancer or by enhancing vital energy in the body. Conclusions: With Body Revival supplements with routine medical care improve their day to day life. To strengthen the present findings, more research is required.

The Areola study: design and rationale of a cohort study on long-term health outcomes in women with implant-based breast reconstructions

BackgroundImplant-based breast reconstructions contribute considerably to the quality of life of breast cancer patients. A knowledge gap exists concerning the potential role of silicone breast implants in the development of so-called “breast implant illness” (BII) and autoimmune diseases in breast cancer survivors with implant-based reconstructions. BII is a constellation of non-specific symptoms reported by a small group of women with silicone breast implants. MethodsThe Areola study is a multicenter retrospective cohort study with prospective follow-up aiming to assess the risk of BII and autoimmune diseases in female breast cancer survivors with and without silicone breast implants. In this report, we set out the rationale, study design, and methodology of this cohort study. The cohort consists of breast cancer survivors who received surgical treatment with implant-based reconstruction in six major hospitals across the Netherlands in the period between 2000 and 2015. As a comparison group, a frequency-matched sample of breast cancer survivors without breast implants will be selected. An additional group of women who received breast augmentation surgery in the same years will be selected to compare their characteristics and health outcomes with those of breast cancer patients with implants. All women who are still alive will be invited to complete a web-based questionnaire covering health-related topics. The entire cohort including deceased women will be linked to population-based databases of Statistics Netherlands. These include a registry of hospital diagnostic codes, a medicines prescription registry, and a cause-of-death registry, through which diagnoses of autoimmune diseases will be identified. Outcomes of interest are the prevalence and incidence of BII and autoimmune diseases. In addition, risk factors for the development of BII and autoimmune disorders will be assessed among women with implants. DiscussionThe Areola study will contribute to the availability of reliable information on the risks of BII and autoimmune diseases in Dutch breast cancer survivors with silicone breast implants. This will inform breast cancer survivors and aid future breast cancer patients and their treating physicians to make informed decisions about reconstructive strategies after mastectomy. RegistrationThis study is registered at ClinicalTrials.gov on June 2, 2022 (NCT05400954).

P256 Quality of life in breast cancer patients, preoperatively and postoperatively. Methods of influencing the quality of life. M. M. Valcan university of oradea, faculty of medicine and pharmacy, romania

P256 Quality of life in breast cancer patients, preoperatively and postoperatively. Methods of influencing the quality of life. M. M. Valcan university of oradea, faculty of medicine and pharmacy, romania

Medico-social substantiation of the issue of quality of life in patients with breast cancer and finding ways to improve it

The quality of life of patients is one of the indicators of the medical care effectiveness for cancer patients. In order to study the main aspects of the quality of life of patients with breast cancer, a survey of 400 patients at the stage of their inpatient treatment in oncological institutions in nine regions of Ukraine (Chernihiv, Zaporizhia, Dnipropetrovsk, Kyiv, Poltava, Khmelnytsky, Ivano-Frankivsk, Zakarpattia and Lviv) using the EORTC QLQ-C30 and EORTC QLQ-BR45 questionnaires was carried out. In Ukraine, as of the pre-war period (November 2021 – February 2022), the quality of life of breast cancer patients equaled 53.22 on a 100-point scale. The most pronounced impact of breast cancer on the quality of life of the patient was observed in the psycho-emotional sphere (71.26), role functioning (70.48), views on future prospects (30.95). Patients complained of financial difficulties (44.19), fatigue (35.16), sleep disturbances (33.00), hair loss (43.41), as well as decreased sexual function (16.06) and pleasure (18.16 points). Given the low quality of life of breast cancer patients, they need psychological support, which should be aimed at adapting to the manifestations of the disease and future prospects, and the quality of life of patients should be one of the indicators in the course of treatment and providing psychological support. Since patients who have received social and psychological support from their doctors and friends/family have higher quality of life, we consider it necessary to focus on developing a comprehensive program to support breast cancer patients in collaboration with society, family and workplace.

Quality of life of breast cancer patients

Introduction: Breast cancer is a type of cancer with the highest incidence among women worldwide. It has an impact on the patient’s physical, psychological, social, and functional health. Breast cancer patients have a greater burden of symptoms, which can lead to decreased quality of life. This study had the objective to describe breast cancer patients’ quality of life in a hospital.Methods: A descriptive observational study design was used. The research population was breast cancer patients in a public hospital. The sample in this study was based on the inclusion and exclusion criteria, with a total of 110 respondents obtained through the proportional sampling technique. The data were analyzed using descriptive analysis. Data were collected by referencing demographic data and distributing a quality-of-life questionnaire (FACT-B). Results: Regarding the quality-of-life variable, findings show that 32 patients had very bad physical well-being (29.1%). Most of the social well-being relations were good, with 40 respondents in this category (36.4%). The majority were in the bad category in terms of functional well-being, with 52 respondents being identified (47.3%). Emotional well-being was considered good for 66 respondents (60.0%). In terms of additional concerns, as many as 60 respondents were in the bad category (54.2%).Conclusions: Chronic conditions can negatively impact patients’ physical health and quality of life. Low quality of life is related to the burden of symptoms experienced by patients, such as anxiety, depression, and fatigue. This suggests that social support can strengthen effective coping and improve patients’ quality of life.Keywords: breast cancer; breast carcinoma; health-related quality of life; quality of life; patients

Quality of life in breast cancer patients over the age of 65 years after organ-sparing treatment with or without radiation therapy

Objective. To study the impact of radiation therapy (RT) after organ-sparing surgery (OSS) for breast cancer (BC) on quality of life (QoL) in patients over the age of 65 years. Subjects and methods. The investigation enrolled 133 patients with Stage IA BC who underwent OSS. The patients were divided into 2 groups: 1) patients who had received RT after surgical treatment; 2) those who had not. All the patients included in the investigation received adjuvant hormone therapy for ≥5 years. The mean follow-up period was 61.77±20.10 months. QoL was comparatively assessed using the EORTC QLQ-C30 Version 3 and EORTC QLQ-BR23 questionnaires. Results. The scores on functional and symptom scales and those on the EORTC QLQ-C30 V.3 Global health status/QoL were statistically comparable in the examined groups (p > 0.05). Statistically significant differences between the groups were obtained in assessing the EORTC QLQ-BR23 Body image (BRBI). Arm symptoms (BRAS), and Breast symptoms (BRBS) (p0.05). Conclusion. After CCA with and without RT, the patients older than 65 years showed no significant differences in the assessment of QoL using the Global health status/QoL symptom, functional, and BRFU scales. QoL assessment using BRBI, BRBS, and BRAS demonstrated lower scores in the RT group. Thus, it may be concluded that RT does not worsen the overall QoL in patients, whereas it exerts local side effects in the area of irradiated tissues.

Abstract P2-21-05: Vascular effects of Platelet-derived growth factor-B (PDGFB) in breast cancer metastasis to the brain

Abstract Brain metastases are associated with shortened survival and poorer quality of life in breast cancer patients. Recently, the importance of platelet-derived growth factor-B (PDGFB) and its stromally localized cognate receptor, platelet-derived growth factor receptor-beta (PDGFRβ) in promoting breast cancer metastasis to the brain was identified by our group. Historically, PDGFB-to-PDGFRβ signaling is known to promote angiogenesis and vessel maturation both in normal physiology and in cancer, but the mechanism(s) behind this tumor stromal interplay in brain metastasis is poorly understood. Based on our previous work and the work of others, we hypothesized that breast tumor-derived PDGFB directly modulates both brain endothelial and blood brain barrier (BBB) function by altering angiogenesis and endothelial permeability. To test this directly, we over-expressed PDGFB ligand in MDA-MB-231 and HCC1187 triple negative breast cancer cell lines and compared the angiogenic potential of the conditioned medium (CM) from these cells. We utilized both a 3D in vitro (human brain microvascular endothelial cell, HBMEC) spheroid angiogenesis model and a tri-culture BBB system (HBMECs in direct interaction with human astrocytes and human pericytes) to test the BBB vasculature. CM harvested from PDGFB overexpressing cells significantly increased the sprouting angiogenesis potential of 3D HBMECs and the migration of 3D tri-culture BBB spheroids compared to CM obtained from parental cells. In addition, CM from PDGFB overexpressing cells caused the surface of BBB spheroids to exhibit significantly increased permeability to high molecular weight dextran compared to CM from parental cells. In agreement with these findings, the tight junction protein ZO1 was diminished. Importantly, in vivo BBB permeability was also tested upon intracardiac injection of MDA-MB-231 cells with and without PDGFB overexpression. These studies revealed that Evans blue dye fluorescence intensity was significantly higher in the brains of mice injected with PDGFB overexpressing cells compared to parental cells. Overall, these studies reveal a previously unrecognized role for PDGFB-to-PDGFRβ signaling in brain vascular remodeling and BBB permeability, which has clinical implications for women with PDGFB-positive breast cancer. Citation Format: Sajita Shah, Rebecca Packard, Sarah Steck, Alexis Mossing, Yalini Ramamoorthy, Katie Thies, Alexander Didier, Jonathan Spehar, Dillon Richardson, Tasneem Arsiwala, Jonathan Godbout, Steven Sizemore, Paul Lockman, Gina Sizemore. Vascular effects of Platelet-derived growth factor-B (PDGFB) in breast cancer metastasis to the brain [abstract]. In: Proceedings of the 2022 San Antonio Breast Cancer Symposium; 2022 Dec 6-10; San Antonio, TX. Philadelphia (PA): AACR; Cancer Res 2023;83(5 Suppl):Abstract nr P2-21-05.

Social functioning, depression, and quality of life among breast cancer patients: A path analysis.

To identify associations among social functioning, depression, and quality of life in breast cancer patients. A cross-sectional study was conducted. A total of 180 breast cancer patients were recruited from the surgical units in southern Taiwan hospital in 2021. Path analysis was employed to analyze the relationships between background information and social functioning, depression, and quality of life. Structural equation modeling (SEM) was used for examining the path analysis in this study. The path model showed that respondents with a religious belief (ß=0.18, p<.000) and less severe disease (ß=-0.29, p<.01) showed better social functioning. Income did not affect social functioning directly but was directly related to the social interaction dimension (ß=0.30, p<.000). Moreover, younger age (ß=-0.29, p<.000, lower income (ß=-0.10, p<.05) and more severe disease (ß=0.35, p<.000) increased the level of depression. Less severe disease would also result in a better quality of life (ß=-0.45, p<.000). Breast cancer patients with better social function levels have low levels of depression (ß=-0.82, p<.000) and better quality of life (ß=0.76, p<.000). Age, religion, income, and severity are crucial predictors of social functioning, depression, and quality of life. Furthermore, severity variables which combined clinical variables to make this variable a stronger predictor for SF, depression, and QOL.

Advances in medical treatment of breast cancer in 2022.

Breast cancer has replaced lung cancer as the most common malignancy worldwide. The 5-year survival rate of breast cancer has reached 90%. Systemic treatment of breast cancer has developed into a mature system including chemotherapy, targeted therapy, endocrine therapy and immunotherapy. This article summarizes the annual progress of breast cancer chemotherapy, targeted therapy, endocrine therapy and immunotherapy in 2022, providing valuable information for future research to better guide individualized treatment of breast cancer, thereby improving the prognosis and quality of life of breast cancer patients.

The Efficacy of Psychoeducational Support Group for Saudi Breast Cancer Survivors.

The adverse effects of psychological distress and quality of life are common outcomes in breast cancer survivors. Psychoeducational interventions have been widely used to reduce these adverse outcomes among those patients. This study aims to assess the impact of the Blossom support group on psychological distress and quality of life in breast cancer patients in Saudi Arabia. This study is a retrospective cohort study for the Blossom program, which was held yearly for eight weeks from 2014 until 2018. Data was collected from the survivors' records at the Zahra Breast Cancer Association in Riyadh, Saudi Arabia. include the quality of life scale (SF-36) and Hospital Anxiety Depression Scale (HADS) with both were available in the Arabic translated version. Both tools were used as the screening measurement for the assessment of the quality of life, depression, and anxiety before and after the program. The data were analyzed using the Statistical Analytical Software (SAS), version 9.4. Statistical differences in median scores of SF-36 and HADS before and after the program was tested using Wilcoxon signed-rank test. A total of 54 breast cancer survivors were enrolled in the Blossom support program over the period 2014 to 2018. Of these participants, only 25 participants completed the full eight weeks program. There were statistically significant differences in the overall quality of life (SF-36) before and after the 8 weeks from baseline of the experiment (W = 60, P-value =0.0125). Moreover, the overall anxiety and depression scores were tested separately and the results reveal statistically significant differences in both dimensions before and after the program (Anxiety: W=132, P-value = 0.0059; depression: W=157, P-value = 0.0002). The Blossom support program showed a positive impact on the quality of life and the psychological well-being of breast cancer survivors. It is recommended to utilize this support program across a wide range of health organizations with breast cancer survivors as a baseline of psychological care to improve the quality of life.

Relationship between family support and quality of life of breast cancer patients undergoing chemotherapy at Santa Elisabeth Hospital, Medan 2022

Introduction: The world today is not only facing the problem of communicable diseases but also non-communicable diseases whose cases are increasing and causing major deaths worldwide. One of them is cancer. Cancer is a disease in which abnormal cells grow uncontrollably, invade and move between cells and tissues. Objectives: To determine the relationship between family support and quality of life of breast cancer patients undergoing chemotherapy at Santa Elisabeth Hospital, Medan 2022. Methods: This type of research is non-experimental using a correlational research design with a Cross-Sectional approach. Results: The results of the study conducted by the researcher showed that the presence of family support can improve the patient's quality of life. Conclusions: the quality of life of breast cancer patients undergoing chemotherapy is getting more optimal. Researchers hope to improve the quality of life for breast cancer patients undergoing chemotherapy by providing positive support such as sincere care and affection, the motivation that builds the patient's spirit.

Latissimus dorsi flap after mastectomy surgery: case series

Background: Breast cancer is the most common type of cancer in women. Breast cancer can be treated with mastectomy surgery, chemotherapy, hormonal, radiation, and biological agent therapy. Surgery is the primary therapy for breast cancer. The most common surgical procedure is a mastectomy which can be continued with breast reconstruction after mastectomy surgery to improve the shape and close the breast defects. Breast reconstructions can be performed with breast implant surgery and autologous or “flap” reconstruction. Latissimus Dorsi (LD) flap is a pedicled flap often used for breast reconstruction. Mastectomy surgery and breast reconstruction complications are seromas, late hypertrophic scars, hematomas, pain, muscle weakness, and infections. This study aimed to describe the case series of latissimus dorsi flaps in breast cancer patients after mastectomy surgery. Case presentation: The author presents 6 cases of breast cancer patients after mastectomy surgery performed breast reconstruction using an LD flap. Five patients had a history of surgery on the abdomen, and one did not have a history of abdominal surgery but had planned pregnancy in the future. There were no complications after LD flap reconstruction surgery. LD flap surgery may be accompanied by implants so that the shape and size can be close to another breast, but related to the cost, and the patients refuse to use a breast implant. All patients were given chemotherapy before surgery. Conclusion: Breast reconstructive surgery is used to close defects after mastectomy surgery and can improve the quality of life of breast cancer patients. Pedicled LD flaps are one of the techniques often used for breast reconstruction cases because of rare complications of necrosis in the donor area or flaps.

Influence of body image on quality of life in breast cancer patients undergoing breast reconstruction: Mediating of self-esteem.

Breast cancer is considered as a major health problem for women, and the prevalence is increasing over the world. Research to improve their quality of life is necessary. This study was to examine the body image and self-esteem of breast cancer patients who underwent breast reconstruction in order to determine whether these affect their quality of life. A cross-sectional descriptive design was employed. This study was conducted on 140 patients who underwent breast reconstruction following breast cancer surgery at S University Hospital in Gyeonggi-do, South Korea. Measures were the general characteristics list, body image scale, self-esteem scale, and the Korean version of the Functional Assessment of Cancer Therapy-Breast Cancer Version 4 for quality of life. Data were analysed using descriptive statistics, Pearson correlation coefficient, linear regression, and process macro bootstrapping for mediation effect. Data were collected from October 2020 to March 2021. The path regression coefficient was 1.59 (p < .001), and the direct effect of body image on the quality of life was 1.34 (p < .001) considering the effect of self-esteem, which is a parameter. This confirmed that self-esteem mediates body image and quality of life. The explanatory power of self-esteem for quality of life was 54%. This study suggests that body image and self-esteem are important factors in the quality of life of breast cancer patients who underwent breast reconstruction. Also, the self-esteem has a mediating effect in the relationship between body image and quality of life. In clinical practice, nurses should focus on the body image and self-esteem of breast cancer patients who have undergone breast reconstruction in order to improve their quality of life. This cross-sectional descriptive design study was conducted on patients who underwent breast reconstruction following breast cancer surgery at hospital in South Korea.

Family support on motivation of compliance and chemotherapy protocol among patients with breast cancer

Chemotherapy is a therapy using drugs to kill cancer cells that have spread beyond the breast and axillary areas that cannot be seen or found. This study aimed to determine the relationship between family support and motivation to comply with chemotherapy protocols in breast cancer patients in Tarakan Hospital Jakarta. This type of research is descriptive and correlative with a cross-sectional approach with the simple random sampling technique of 73 respondents—the results of the research data analysis using the Chi-Square test. From the study's results, it can be concluded that there is a significant relationship between family support and motivation to comply with chemotherapy protocols in breast cancer patients. Therefore, family support is needed to improve the quality of life in breast cancer patients undergoing chemotherapy.&#x0D; Keywords: Chemotherapy; breast cancer; nursing care; nursing collaboration; family support

360 Health Analysis (H360) – Quality of Life of Breast Cancer Patients: an Integrated Vision

Background: This study is part of the H360 Health Analysis (H360) and aimed to investigate the Quality of Life (QoL) of Breast Cancer (BC) patients in the real world.

Quality of Life in Breast Cancer Patients Treated With Mistletoe Extracts: A Systematic Review and Meta-Analysis.

Breast cancer is the most common cancer type in women and quality of life an essential part of patients' well-being. Although the treatment with mistletoe extracts is covered by multiple cancer guidelines and reviews, it is uncertain whether mistletoe extracts can improve the quality of life in breast cancer patients. We therefore performed a systematic review and meta-analysis on this topic. This systematic review included randomized clinical trials (RCTs) and non-randomized studies of intervention (NRSIs) comparing the quality of life in breast cancer patients treated with mistletoe extracts as add-on therapy to control groups treated conventionally. We searched previous systematic reviews and multiple databases until January 2023. We conducted a meta-analysis and assessed the risk of bias according to the Cochrane Handbook via RoB 2 and ROBINS-I and the certainty of evidence via GRADE, respectively. Nine RCTs and 7 NRSIs with 833 and 2831 participants, respectively, were included. The pre-post changes for the quality of life resulted in a pooled standardized mean difference for RCTs of SMD = 0.61 (95% CI 0.47-0.75; P < .0001) and for retrospective NRSIs of SMD = 0.46 (95% CI 0.10-0.82; P = .01). The risk of bias was low to high for the RCTs and serious for all NRSIs. The certainty of evidence was moderate for RCTs and very low for NRSIs. Our results indicate a clinically relevant, medium-sized effect of mistletoe extracts on the quality of life in breast cancer patients which may be based on the immunomodulating effects of mistletoe extracts during chemotherapy. The limitations of evidence include the risk of bias which is mainly caused by the difficulty of blinding. Further RCTs and real-world evidence need to confirm this result, especially in the setting of neoadjuvant chemotherapy and in breast cancer survivors.

Does Digital Rubbing Massage-Pain Relief (DRM Pain Relief) Affect Breast Cancer Patients' Pain, Comfort, and Quality of Life?

The incidence of breast cancer in Indonesia is the highest among types of cancer in women, with an estimated pain prevalence of 40%-89%. More than 50% of cancer patients suffer from pain that has not been resolved. Cancer pain's impact will affect the comfort level and quality of life. The purpose of this study was to analyze the effectiveness of DRM Pain Relief on the degree of pain, comfort, and quality of life among breast cancer patients. The research was a true experimental study with pre-test and post-test designs with a control group. The population was all breast cancer patients attending hospitals in Semarang and Pekalongan Districts. The research subjects were 64 respondents who met the inclusion and exclusion criteria. Respondents were selected randomly and divided into two groups, namely 32 in the treatment group (DRM Pain Relief application) and 32 in the control group (only received drugs as conventional therapy in the hospital). Data were analyzed using a multivariate test. The application of DRM Pain Relief was effective in reducing the degree of pain (p < .001), and effectively increasing comfort (p < .001), as well as improving the quality of life of breast cancer patients in the components of improvement in symptom status, functional status, and global quality of life with p-value <.001, .003, < .001, respectively. The DRM Pain Relief effectively reduces the degree of pain, increases comfort, and improves the quality of life of breast cancer patients.

Comparison of Quality of Life Between Breast Cancer Patients Treated With and Without Adjunctive Traditional Chinese Medicine in Taiwan.

In Taiwan, breast cancer has the highest incidence among all cancers. Although adjunctive traditional Chinese medicine treatment (TCM) have been used to ameliorate the side effects or discomfort caused by cancer treatments, no study has focused on the assessment of the quality of life of patients undergoing adjunctive TCM treatments. This study compared the quality of life between breast cancer patients treated with and without adjunctive TCM. Questionnaires were collected from 7 hospitals with a Chinese medicine clinic in 2018 to 2019. Breast cancer patients who had cancer stages I, II, or III and also underwent resection surgery were included in the study. They were divided into 2 groups: patients receiving cancer treatments with adjunctive traditional Chinese medicine (TCM group) and those receiving cancer treatments without adjunctive traditional Chinese medicine (non-TCM group). A 1:1 matching was used to obtain the study participants. The EQ-5D questionnaire was used to assess the quality of life. Statistical analysis was performed using the t-test and ANOVA to compare the differences between variables. The conditional multiple regression model was applied to explore the factors associated with quality of life in breast cancer patients. A total of 543 participants were surveyed, and 450 participants were included in the study. The EQ-5D score of the TCM group (81.60 ± 11.67) was significantly higher than that of the non-TCM group (78.80 ± 13.10; P < .05). The results of a conditional multiple regression model showed that the TCM group had a higher (3.45 points) quality of life than non-TCM group (P = .002) after adjusting for other related factors. After stratifying by cancer stage, patients with cancer stages II and III scored 5.58 and 4.35 points higher in the TCM group than did those in the non-TCM group (P < .05). Breast cancer patients undergoing cancer treatment with adjunctive traditional Chinese medicine have a higher quality of life than those treated without adjunctive traditional Chinese medicine.

Quality of life of breast cancer patients

WHO in 2019 has reported 2.09 million cases and 62, 7000 deaths of breast cancer in women. It affects women in the developing and developed countries across the globe. In our country, breast cancer is the most common form of cancer, among women which begins in the early thirties and peaks at 60-65 years of age. Breast cancer if detected early can be treated. The study was done to assess Quality of Life among breast Cancer patients. Using Sister Callista Roy’s General system theory this descriptive study was done on 100 Breast Cancer patients in Oncology OPD using QOL tool. Study findings revealed that with all treatment and follow-up regimes too only 54% had a good QOL rest being affected with disease and having some or other issues. To conclude even if there are extensive advancements in treatment modalities related to the Breast cancer still the fears, finances and social activities are widely affected.

Breast cancer and body image: The roles of the male partner

Background: Cancer is a group of diseases with different causes, manifestations, treatment, and prognosis, characterized with an uncontrolled growth of abnormal cell. In women; cancer of the breast is the second most common cancer after cervical cancer and the second leading cancer’s death following lung cancer among women in Sub-Saharan Africa. In Nigeria, it has become the most common female malignancy with a prevalence of 12.5%. However, the same treatment that offers better cure rates may also result in a serious decrease in quality of life, psychological problems, as well as provoking changes in their bodies. Societal behavior towards breast cancer patients makes a woman that is newly diagnosed with breast cancer become tearful, ashamed, and discouraged. Aims: To examine breast cancer, body image and the roles of the male partner. Methods: The data for this review paper are from published studies. Electronic databases of Medline, Scopus, PubMed, CINAHL, and Google Scholar were searched using the keywords: breast cancer, body image, roles of the male partner and literature were retrieved and screened for eligibility. The date limit considered in the literature search was from 2016-2021 to capture only the variables identified in this seminar objective. The author defined the topic of interest and the goal was to address the objective of the seminar topic. Results: Four themes (issues) emerged which are: (1) The Model of Whole-Person Caring, (2) Disturbed Body Image, (3) Psycho-Social Impact of Breast Cancer and (4) Roles of the Male Partner. Conclusion: Breast cancer poses a significant financial and psychosocial burden not only on patients, but also on their spouses, families, and broader social network. Breast cancer disease usually changes spousal roles as the women’s husbands take over their responsibilities. The disease influenced both partners and made stress a common factor shared by them. Husband plays a vital role in the lives of breast cancer patients through managing the finance, decision-making, providing emotional support, and remaining involved throughout the disease. Therefore, involving the husband in planned psycho-social interventions produces better results than merely patient-focused strategies. Male partners have a great role to play and should be encouraged and allow partaking in the treatment process of their spouses as this will positively influence their recovery.