Jetyasar archaeological culture was discovered and studied by the Khorezm expedition of the Institute of Ethnography of USSR. According to archeological data, this culture experienced many times transformations due to the influx of new population groups. This article presents for the first time complete data on paleodemography of samples from nineteen burial grounds of Altyn-Asar 4a–t, Kosasar 2 and Tompakasar, taking into account frac-tional chronological differentiation. We examined anthropological materials from over 600 burials in the storage of the Institute of Archeology RAS. In total samples from Altyn-Asar 4 of the 2nd c. BC. — 4th century was mentioned to the weak numerical predominance of females. The sex ratio in favor of males changed in the 4th–6th centuries. The average age at death of the adult population decreased by the 6th century, primarily among men. Data on separate cemeteries allow a more differentiated assessment of the chronological dynamics of demographic indi-cators. The numerical predominance of male burials was found: in the 2nd c. BC. — 4th c. AD in burial grounds Kosa-sar 2, Altyn-Asar 4 m; in the 4th–6th c. in the Altyn-Asar necropolises 4a, b, o, v. In opposite to the most groups, the Kosasar 2 sample stands out with its demographic profile and increased average age of death for males and fe-males. According to archeological data, it may be associated with Xiongnu migration. In 2nd–4th centuries the number of this group was falling, it showed a decrease in life expectancy for men, however, for this period, it seems to be comparable the maximal one. Their antagonists during this period were representatives of other group of incomers, buried in necropolis AA4m, with a low life expectancy for males and females. Despite the supposed influx of new-comers, it is obvious that the genetic continuity of a part of the Jetyasar population, which probably belonged to in-fluential local clans (the necropolises of Altyn-Asar4l and later Altyn-Asar4r), might be evident.