Part Of Library Research Articles

The Study on Mold Design System in Mechanical Engineering

By investigating the characteristics of mold design in mechanical engineering, a framework of computer aided design tool is designed. A standard part library based on Client/Server mode and management tools are designed. The system improves the intelligence by introducing case-based design method

유닛모듈러 주택의 BIM 라이브러리 개발 연구 - 소규모 도시형 생활주택을 중심으로 -

This Study developed library of parts, applied with 3-dimension character which has width, length and height and a reference plane, for the system development of BIM design on housing unit modular. The current BIM software has not the concept of a reference plane or work tolerance in modular, so the development of parts library applied to unit modular has not moved forward. So, we developed, in this study, parts library applied to windows, built-in-furniture, kitchen systems and knock down bathrooms, with a reference plane and work tolerance based on single roon prototype on urban-life-housings. BIM library can utilize changed size and work tolerance of parts, and fabricating reference plane will be created automatically when an engineer puts work tolerance in the BIM library with supplement of some category related to work reference. Through this BIM library development, we consider the part module can be used for housing complex planning, and architectural designers will be able to utilize the BIM library for housing complex design.

A synthetic biology approach to self-regulatory recombinant protein production in Escherichia coli

BackgroundRecombinant protein production is a process of great industrial interest, with products that range from pharmaceuticals to biofuels. Since high level production of recombinant protein imposes significant stress in the host organism, several methods have been developed over the years to optimize protein production. So far, these trial-and-error techniques have proved laborious and sensitive to process parameters, while there has been no attempt to address the problem by applying Synthetic Biology principles and methods, such as integration of standardized parts in novel synthetic circuits.ResultsWe present a novel self-regulatory protein production system that couples the control of recombinant protein production with a stress-induced, negative feedback mechanism. The synthetic circuit allows the down-regulation of recombinant protein expression through a stress-induced promoter. We used E. coli as the host organism, since it is widely used in recombinant processes. Our results show that the introduction of the self-regulatory circuit increases the soluble/insoluble ratio of recombinant protein at the expense of total protein yield. To further elucidate the dynamics of the system, we developed a computational model that is in agreement with the observed experimental data, and provides insight on the interplay between protein solubility and yield.ConclusionOur work introduces the idea of a self-regulatory circuit for recombinant protein products, and paves the way for processes with reduced external control or monitoring needs. It demonstrates that the library of standard biological parts serves as a valuable resource for initial synthetic blocks that needs to be further refined to be successfully applied in practical problems of biotechnological significance. Finally, the development of a predictive model in conjunction with experimental validation facilitates a better understanding of the underlying dynamics and can be used as a guide to experimental design.

The Development of Brake Three-Dimensional Parts Library Based on CATIA

In the past, when need to draw one model of brake parts, users have to use the CAD software and make it one step by step, which wastes a lot of time and energy because of the repetitive artificially drawing. In order to improve the efficiency of drawing the models of brake parts, the paper builds one brake parts library by using the Visual C++6.0 and doing secondary development on the CATIA. Through one example, the paper proves the feasibility of building brake parts library.

User-Group Requirements Based Approach for the Standardization of Parts

Standardization of mechanical parts across enterprise and in large scope is benefit to promote the reuse degree of parts and improve the specialization and co-ordination of industrial production. In this paper, a user-group requirements based approach for standardization of part is proposed. The main idea of the approach is to collect, statistic and analyze the users’ requirements of mechanical parts through the web-based parts library and then construct the evaluation index system to instead the traditional parts spectrum analysis which used in GT (Group Technology). The key steps and methods are discussed and the application case is introduced for verifying the proposed approach.

METABOLIC MODELLING IN THE DEVELOPMENT OF CELL FACTORIES BY SYNTHETIC BIOLOGY

Cell factories are commonly microbial organisms utilized for bioconversion of renewable resources to bulk or high value chemicals. Introduction of novel production pathways in chassis strains is the core of the development of cell factories by synthetic biology. Synthetic biology aims to create novel biological functions and systems not found in nature by combining biology with engineering. The workflow of the development of novel cell factories with synthetic biology is ideally linear which will be attainable with the quantitative engineering approach, high-quality predictive models, and libraries of well-characterized parts. Different types of metabolic models, mathematical representations of metabolism and its components, enzymes and metabolites, are useful in particular phases of the synthetic biology workflow. In this minireview, the role of metabolic modelling in synthetic biology will be discussed with a review of current status of compatible methods and models for the in silico design and quantitative evaluation of a cell factory.

Modeling Method of 3D Standard Parts Library Based on Virtual Prototyping Technology

This paper proposed a virtual prototyping-based modeling method of standard parts library. After the design requirement analysis, the modeling approach was put forward. Then the parameter-driven method and its use method were then proposed. The classes object organization relationship was identified step by step. The fastening feature tree structure logical relationship was present as an example, which demonstrates that this method is obviously helpful to product design.

모듈러 강교량 상부모듈의 조립체계 정의를 통한 IFC 기반의 부품정보 표현방법

모듈러 강교량 제작, 조립, 설계, 시공단계에서 상부모듈의 부품정보를 효율적으로 제공하고 교환하기 위하여 BIM(Building Information Modeling) 프로젝트에서 정보교환을 위하여 사용하는 국제표준인 IFC 모델을 활용한 부품정보 라이브러리 구축방법을 제시하였다. 모듈러 강교량의 상부모듈을 구성하는 부품정보를 IFC 모델로 표현하기 위하여 의미론적인 관점에서 기존 IFC 모델에서 부품정보를 표현할 수 있는 엔티티와 모듈러 강교량의 구성요소를 매칭하여 적용하였으며, 구성요소의 역할을 구분하기 위하여 매칭한 엔티티의 타입을 적용하거나 사용자정의 타입으로 정의하였다. 또한, 부품 정보 라이브러리에서 부품 및 조립품의 정보를 해당단계에서 효율적으로 제공하기 위하여 조립체계를 네 단계의 상세수준(LoD)으로 구분하여 정의하였으며, 이를 IFC 모델로 표현하기 위하여 새로운 속성정보를 정의하였다. 마지막으로, IFC 모델과 매칭하여 정의한 정보를 실제 모듈러 강교량 상부모듈에 적용하여 IFC 기반의 시범 라이브러리 정보를 생성하였다. IFC-based representation method of part library for superstructure module of modular steel bridge is proposed. The library is capable of efficiently offering and exchanging part information in process of manufacture, assembly, design, and construction of modular steel bridge. Entities, representing physical part information in IFC model, are matched semantically with parts of the superstructure module for representation of part information with IFC model. Either types of matched entities are applied in order to verify the role of each part, or new types are defined as a user-defined types. In addition, assembly system has been classified and defined into 4 levels of LoD(Level of Detail) to provide appropriate part information efficiently from the part library in each step of the process. Then, new property is defined for representing the LoD information with IFC Model. Finally, IFC-based test library of modular steel bridge is generated by applying the matched entities and entity types to the actual the superstructure module of modular steel bridge.

The PLOS ONE Synthetic Biology Collection: Six Years and Counting

Since it was launched in 2006, PLOS ONE has published over fifty articles illustrating the many facets of the emerging field of synthetic biology. This article reviews these publications by organizing them into broad categories focused on DNA synthesis and assembly techniques, the development of libraries of biological parts, the use of synthetic biology in protein engineering applications, and the engineering of gene regulatory networks and metabolic pathways. Finally, we review articles that describe enabling technologies such as software and modeling, along with new instrumentation. In order to increase the visibility of this body of work, the papers have been assembled into the PLOS ONE Synthetic Biology Collection (www.ploscollections.org/synbio). Many of the innovative features of the PLOS ONE web site will help make this collection a resource that will support a lively dialogue between readers and authors of PLOS ONE synthetic biology papers. The content of the collection will be updated periodically by including relevant articles as they are published by the journal. Thus, we hope that this collection will continue to meet the publishing needs of the synthetic biology community.

The Development of Web-Based Parts Library for Typical Mechanical and Electric Industries

In order to share and reuse the abundant standardization and serialization parts resource in typical mechanical and electric industries, it is an efficient option to develop a pats library management system in networked manufacturing environment. Therefore, the framework of web-based parts library is discussed based on B/S mode and .NET framework. Especially, key technologies for developing this system are studied, including methods for parts resource classifying and encoding, database design and access, no-refresh browsing of 3D part model, and system security mechanism and so on. At last, a prototype system is present.

The Application of Second Development Technology for SolidEdge in Web-Based Parts Library

One of the purposes of building a web-based PLIB is to transform the CAD technology application from isolated environment to network. To realize the main function modules of web-based PLIB system, the object hierarchies of SolidEdge and its Second Development Technology under .NET Platform are studied. And on this basis, the implementation methods of these function modules closely related with the SolidEdge API (Application Program Interface) are detailed, including the dynamic browsing of three-dimensional part model, the online parametric design of part, the information acquisition of part property. At last, an application instance is presented.

The Development of Parametric Part Library Based on WEB

To meet the need of sharing three-dimension model among different CAD/CAM software users and enterprises, and to realize the functions of parameterizing three-dimension model, managing and expanding the data in system, a system of parametric part library is developed by using the technologies of secondary development for CAD/CAM software, ASP.NET, Database and Web3D comprehensive. This paper gives the way and process of realizing the functions above, and an instance of system is given in the paper.

Application of Ug Re-Development Technology in 3-D Parameterized Modeling of Injection Mould Parts

On the foundation of deeply studying UG re-development technology and synthetically utilizing its secondary development tools, including UG/Open MenuScript, UG/Open UIStyler, UG/Open API and Visual C++ 6.0, a dedicated 3D parts library of injection mold is established, parameterized design of injection mold is achieved and mold design efficiency improved.

Study on Key Technologies of Web Parts Library System Development

Through the development of the web parts library system, this paper intensively studies the secondary development technology of Pro/E in asynchronous mode on the .NET platform, using C # programming language, dynamically browsing three-dimensional parts technology on line and on-line parameterized driving technology, and with ADO.NET network programming technology, achieves on-line connecting database. With all the key technologies researched above, it demonstrates the feasibility of achieving each function and process of web parts library system.

The Development Mode of Mechanical and Electrical Products 3D Part Library

According to the requirements to reuse the design resources such as the three-dimensional parametric part models in the new products development process, the key issue to develop the 3D part library which its content can be expanded and recombined are researched based on the Part with the character of standardization and universal. The paper provid the object and the system structure of this 3D part library firstly. Then, the method to classify the Part data and the corresponding storage way are discussed according to the function of the classified Part data.Finally the method to develop management program of this 3D Part library is discussed based on the Pro/E and Access. The method provided in the paper can be a general way to develop 3D part library for different application field.

Development of Standard Part Library Based on SolidWorks

Mechanical Design Handbook oriented standard part library system of jaw clutches is developed based on SolidWorks. The system consists of three elements, namely a dimension parameter database, a user interface, and a modeling function module. The jaw clutch dimension parameter database is designed based on national standards. According to designers’ thinking habit, a visual user interface is customized to make easy use of the dimension parameter database. The data relationship between the modeling function module and dimension parameter database is established by using parametric program driven method. The jaw clutch standard part library with characteristics of friendly user interface and expansible database is easy to use. The approach adopted in the paper can be used to develop other general 3D standard part library on SolidWorks.

Foundations for the design and implementation of synthetic genetic circuits

Synthetic gene circuits are designed to program new biological behaviour, dynamics and logic control. For all but the simplest synthetic phenotypes, this requires a structured approach to map the desired functionality to available molecular and cellular parts and processes. In other engineering disciplines, a formalized design process has greatly enhanced the scope and rate of success of projects. When engineering biological systems, a desired function must be achieved in a context that is incompletely known, is influenced by stochastic fluctuations and is capable of rich nonlinear interactions with the engineered circuitry. Here, we review progress in the provision and engineering of libraries of parts and devices, their composition into large systems and the emergence of a formal design process for synthetic biology.

Synthetic Biology: An Emerging Engineering Discipline

Over the past decade, synthetic biology has emerged as an engineering discipline for biological systems. Compared with other substrates, biology poses a unique set of engineering challenges resulting from an incomplete understanding of natural biological systems and tools for manipulating them. To address these challenges, synthetic biology is advancing from developing proof-of-concept designs to focusing on core platforms for rational and high-throughput biological engineering. These platforms span the entire biological design cycle, including DNA construction, parts libraries, computational design tools, and interfaces for manipulating and probing synthetic circuits. The development of these enabling technologies requires an engineering mindset to be applied to biology, with an emphasis on generalizable techniques in addition to application-specific designs. This review aims to discuss the progress and challenges in synthetic biology and to illustrate areas where synthetic biology may impact biomedical engineering and human health.

Application and Management of Modular Fixture Parts Library Based on SolidWorks

According to the characteristics of fixture, a method is introduced to develop a modular fixture parts library by using visual programming language VC + +, SolidWorks API interface and configuration technology. First of all, the modular fixture Library has been established through the configuration technology of driving parameters. Secondly, it is programmed to generate a pop-up menu and SolidWorks plug-ins to achieve the module fixture parts call. At the same time, management and utilization of the modular fixture Library is completed, providing users with rapid fixture design based on 3D modeling environment, and contributing to the promotion and application of CAD technology in the machine tool industry

The Forming for the Link Wheel Parts Library and the Corresponding Two-Dimentional Engineering Drawings Based on Pro/E

Introduced a kind of method which can establish machinery parts library based on Pro/E, the practical method is easy to grasp. The process of forming parts library is showed combing with Link Wheel living modeling. At the same time, gave the corresponding two-dimensional projection drawing.