Root Level Research Articles

Determining the Algorithm of Rehabilitation Procedures in Patients with Brachial Plexus Injuries Based on the Prospective Single-Centre Clinical Neurophysiology Studies: Preliminary Results

The clinical neurophysiological tests allow us to determine the type, extent, and nature of brachial plexus damage. They are crucial in decision making regarding surgical procedures or conservative treatment. This report aimed to present an algorithm for rehabilitation procedures in patients with brachial plexus injury of various origins based on the results of neurophysiology findings for the selection of procedures supporting the process of nerve and muscle regeneration. The research group consisted of patients whose medical documentation was analysed concerning the reason, level, and localization of damage to the brachial plexus structures, surgical and or rehabilitative treatment, as well as the MRI results. Among the group of fourteen patients, the clinical studies showed the greatest incidence of brachial plexus injuries of the mixed (both pre- and postganglionic), all trunks, and cervical root injuries, respectively. Results of the motor evoked potentials (MEP) and electroneurography (ENG) recordings induced at levels of spinal roots and Erb’s point showed a decrease of more than 40% in amplitudes on the symptomatic side in comparison to the asymptomatic side. This diffeence was recorded for the axillary and radial innervation and the C5, C6, and C7 root domains, ranging from 57% to 66%; the lowest decrease was recorded following electrical stimulation at Erb’s point for the ulnar nerve (34%). The latency prolongation on the symptomatic side in CMAP and MEP tests ranged from 0.2 to 1.7 ms, with the most following magnetic stimulation of the C5 cervical root for the axillary innervation. Most of the results indicated the axonotmesis and neuropraxia type of injury in motor fibers (40%) confirmed by EMG results. The sensory conduction studies (SNCS) in distal nerve branches did not confirm the severe advancement of the brachial plexus injury (63%). The proposed algorithm of the physiotherapeutic procedures should be mainly targeted for recovery of motor dysfunction as the consequence of brachial plexus injury. Rehabilitation should incorporate the treatment supporting nerve regeneration, muscle strengthening, and maintaining functional ranges of motion of the injured extremities. The rehabilitation treatment for patients with brachial plexus injuries is an individualised process, and the selection of procedures and the effectiveness of the treatment undertaken should be confronted with results of neurophysiological tests verifying the motor neural transmission from the level of the cervical motor centre to the effector, peripheral nerve function, and muscle’s motor unit activity.

An Efficient Method for the Propagation of Bougainvillea glabra ‘New River’ (Nyctaginaceae) from In Vitro Stem Segments

Bougainvillea, an evergreen climbing shrub of the Nyctaginaceae family, holds significant ornamental, economic, and medicinal value. Bougainvillea glabra ‘New River’ is widely used in landscapes due to its strong adaptability to the environment, abundance of flowers, and frequent flowering. Traditionally, Bougainvillea glabra ‘New River’ cultivation has relied on methods such as cuttings or grafting, with limited research on in vitro tissue culture propagation. This study aimed to optimize the tissue culture system, exploring a combination of plant growth regulators (PGRs) for Bougainvillea regeneration from in vitro stem segments. The Murashige and Skoog (MS) medium supplemented with indole-3-butyric acid (IBA), 6-benzylaminopurine (6-BA), and 1-naphthlcetic acid (NAA) was employed. The optimal sterilization of Bougainvillea stem segments involved a 30 s treatment with 75% alcohol and 10 min with 1% NaClO. The synergistic effect of 0.1 mg·L−1 of NAA and 2.5 mg·L−1 of 6-BA maximized the shoot sprouting frequency, while 2.5 mg·L−1 of 6-BA and 0.1 mg·L−1 of NAA produced the maximum shoots. Furthermore, 1.5 mg·L−1 of IBA and 0.1 mg·L−1 of NAA induced the highest rooting levels. This work demonstrates the successful adaptation of a greenhouse environment to efficiently regenerate plants in vitro from stem segments. This approach allows for the mass production of Bougainvillea glabra ‘New River’.

Experimental accumulation and depuration kinetics and natural occurrence of microcystin-LR in basil (Ocimum basilicum L.)

Microcystin-LR (MC-LR) is a hepatotoxic metabolite that naturally occurs during some cyanobacterial blooms in eutrophic waterbodies, and irrigation of edible plants with MC-LR-contaminated water causes bioaccumulation of the toxin. However, sufficient information about accumulation and depuration mechanics in hydroculture-grown herb plants is still lacking. This work aimed at 1) investigating bioaccumulation and depuration of MC-LR in basil, 2) verifying the possible MC-LR detoxification mechanisms in the plant, and 3) detecting the natural occurrence of MC-LR in basil (n = 50) collected from the Belgian market. Basil plants grown in a hydroculture were exposed to MC-LR (5, 20, and 50 μg L−1) spiked in a Hoagland solution for seven days. MC-LR depuration was also studied by transferring the plants to a non-contaminated Hoagland solution after exposure to MC-LR for another seven days. MC-LR concentrations in Hoagland solution, basil leaves, and roots were quantified using a validated UHPLC–MS/MS method. In addition, ELISA and LC–HRMS (only basil leaves) were used for confirmation. The results showed an increase in the accumulated levels of MC-LR at higher exposure doses, with higher MC-LR levels in roots than in leaves for all the treatment conditions. For MC-LR depuration, significant reductions were observed in all the treatment conditions for roots only. No MC-LR conjugates, potentially related to metabolism, were detected by LC–HRMS. Finally, MC-LR was detected in one store-bought basil sample, representing the first occurrence of cyanotoxins in an edible crop from Belgium.

Two-way NxP fertilisation experiment on barley (Hordeum vulgare) reveals shift from additive to synergistic N-P interactions at critical phosphorus fertilisation level.

In a pot experiment, we investigated synergistic interaction of N and P fertilisation on barley biomass (Hordeum vulgare) on both shoot and root level with the aim to determine whether N-P interaction would be the same for all levels of N and P fertilisation. We further aimed to determine whether there was a critical level of N and/or P fertilisation rate, above which, a decrease in resource allocation to roots (as nutrient availability increased) could be demonstrated. Barley plants were grown from seed on a nutrient poor substrate and subjected to a two-way NxP fertilisation gradient using a modified Hoagland fertilisation solution. We observed N-P interactions in shoot and root biomass, and N and P use-efficiencies. A synergistic response in biomass was observed only above a critical level of P fertilisation when P was not limiting growth. Furthermore, we found that the same incremental increase in N:P ratio of applied fertiliser elicited different responses in shoot and root biomass depending on P treatment and concluded that barley plants were less able to cope with increasing stoichiometric imbalance when P was deficient. We provide, for the first time, stoichiometric evidence that critical levels for synergistic interactions between N-P may exist in crop plants.

The Intellectual Representative of the School of objective Criticism: Azhar Ghouri

Object oriented approach of criticism has its roots in post continental philosophies based on perdiction and vision. Azhar Ghouri has strong advocacy for universalization of values and global adaptation of critical thinking styles. He believes in sublimity of Art and architecture regardless of classic or modern as a label for critical analysis. He believes in exploration of ideas and vision with insight in any piece of literature beyond its mechanical structure. Colonialism, exploitation, industrialisation, hunger, fear, shelter, peace and justice are controversial in global village according to A. G which needed to be reflected in art and literature in modes of individual’s interest. Author of this artical has explored gross root level realities and fundamental beliefs of object oriented approach in literary works of A.G. The agitation through pen has always been an eye opener initiative to stimulate the reader same has been highlighted by the author in the artical.

Design and Implementation of CMOS and Transmission Gate Based Full Adder Using 45nm Technology

Abstract: In electronic industry the level of integration is an important aspect as it makes the electronic device simpler and more reliable. The device density increases with the better level of integration. Power dissipation, Area occupied, and Propagation delay are some of the important factors that need to be considered. These parameters play a vital role in manufacturing portable electronic gadgets. Many binary adders are formed using full adders. Hence, if any enhancements have to be made to improve the performance, it can be made at the root level i.e., adders circuits itself. This in turn helps in bettering the performance of the electronics circuits which follow adder circuits. The low power VLSI design is of great importance due to portable electronic products. Full adder is a type of adder circuit that adds three inputs and gives two outputs. Out of three, two will be the present inputs and the third input will be the carry from the previous stage. ‘A’ and ‘B’ are the actual inputs, ‘C’ is the carry from the previous operation. SUM and CARRY OUT are the two outputs. In this work, Design and Implementation of full adder using conventional CMOS design and Transmission gate based Full adder circuits are carried out. At last comparison is made between the two designs with respect to power dissipation, delay and area (number of transistors). Cadence Virtuoso Tool is used in design and simulation conventional CMOS design and Transmission gate based Full adder circuits. The entire circuit is simulated in Cadence Tools at 45nm CMOS process.

Implementation and Analysis of CMOS and Pass Transistor Logic Based Full Adder Circuits

Abstract: In electronic industry the level of integration is an important aspect as it makes the electronic device simpler and more reliable. The device density increases with the better level of integration. Power dissipation, Area occupied and Propagation delay are some of the important factors that need to be considered. These parameters play a vital role in manufacturing portable electronic gadgets. Many binary adders are formed using full adders. Hence, if any enhancements have to be made to improve the performance, it can be made at the root level i.e., adders circuits itself. This in turn helps in bettering the performance of the electronics circuits which follow adder circuits. The low power VLSI design is of great importance due to portable electronic products. Full adder is a type of adder circuit that adds three inputs and gives two outputs. Out of three, two will be the present inputs and the third input will be the carry from the previous stage. ‘A’ and ‘B’ are the actual inputs, ‘C’ is the carry from the previous operation. SUM and CARRY OUT are the two outputs. In this work, Design and Implementation of full adder using conventional CMOS design and Pass Transistor Logic based Full adder circuits are carried out. At last comparison is made between the two designs with respect to power dissipation, delay and area (number of transistors). Cadence Virtuoso Tool is used in design and simulation conventional CMOS design and Pass Transistor Logic based Full adder circuits. The entire work is simulated in 180nm CMOS technology.

Arbuscular mycorrhizal fungi induce Zn uptake and antioxidant efficiency in broccoli (Brassica oleracea L.) exposed to Zn deficiency

Zinc (Zn) is an essential micronutrient for plant growth and development, and its deficiency in soil can be a significant problem for broccoli (Brassica oleracea L.) production. While the genetic efforts to breed Zn-efficient broccoli are complex, harnessing microbiomes is an emerging way to induce mineral efficiency in crops. In this study, broccoli, a non-host mycorrhizal species, was cultivated with or without zinc deficiency in the presence or absence of arbuscular mycorrhizal fungi (AMF), confirmed by the colonization efficiency in roots. Zn deficiency caused a significant decrease in morphological parameters and photosynthetic attributes being consistent with the decreased Zn levels in root and shoot relative to Zn-sufficient plants. However, the broccoli plants inoculated with AMF showed a substantial improvement in morphological and photosynthetic parameters in Zn-deficient conditions due to the significant increase in tissue Zn levels. In addition, AMF-inoculated plants under Zn deficiency showed a significant decrease in cell death (%), electrolyte leakage, and H2O2 levels compared to Zn-deficient plants, which further suggests the improvements in cellular status due to the AMF colonization. The real-time PCR experiments showed a significant induction in the expression of BoZIP1 and BoNRAMP1 genes in the roots of Zn-deficient broccoli inoculated with AMF, suggesting that AMF may be associated with the induction of these genes responsible for Zn-uptake and transport. We further observed the induction of POD (peroxidase), APX (ascorbate peroxidase) and SOD (superoxide dismutase), and S-metabolites (cysteine and glutathione) predominantly in the roots of Zn-starved broccoli inoculated with AMF which may confer tolerance to Zn-deficiency induced oxidative damage. This is the first report on the role of AMF in mitigating Zn-deficiency in broccoli which may promote the microbiome-aided improvement in plant health suffering from Zn-deficiency in broccoli and other vegetable crops.

Identification and characterization analysis of the HDM gene family in melon (Cucumis melo L.).

Histone demethylase (HDM) play crucial roles in regulating plant growth and environmental adaptation. In this study, the HDM gene family in melon was identified by bioinformatics methods and the expression patterns of the CmHDM family members in different melon tissues were analyzed using transcriptome data. The results showed that 20 CmHDM genes were identified in the melon genome, which were unevenly distributed across each chromosome. These members fall into two major categories: LSD1 and JmjC. The JmjC group could be further divided into five subgroups with different numbers. The results of collinearity analysis of intraspecific and interspecific relationships showed that there were only one pair of segmental duplication in melon HDM genes, and more collinearity in genetic relationship of HDM genes between melon and tomato. The numbers of conserved domains, exons and introns in each member vary and various cis-acting elements responding to hormones and environmental signals existed in the respective promoter regions. Expression analysis showed that the respective gene members were expressed at different levels in male flowers, female flowers, roots, stems, leaves, ovary, and mature fruits of melon. These results will contribute to the understanding on the potential functions of the HDM genes and their potential functions in regulating melon growth and environmental adaptation.

Comparative Evaluation of the Efficacy of Different Ni-Ti Rotary Instruments in Removal of Gutta-Percha During Root Canal Retreatment: An in vitro Study

Aim: An assessment and comparison of three retreatment files was conducted to determine their effectiveness in the retrieval of gutta-percha. Materials and Method: In the investigation, 60 extracted single-rooted human teeth having straight canals and complete apices were used. The ProTaper Universal file system was used to prepare teeth and obturated using gutta-percha with sealant AH Plus utilizing down pack and backfill obturation technique. Removal was performed with ProTaper, D-RaCe files, MTwo, and R-Endo retreatment files. Using a stopwatch, the time needed to take out the GP was also calculated in seconds. We used ANOVA along with the post hoc Tukey’s test to analyze the quantity of obturating material in apical, middle, and coronal third following decoronation and longitudinal splitting. Results: The average percentage of gutta-percha points removed across root levels varied significantly among the ProTaper, D-RaCe MTwo, and R-Endo groups. With the exception of the ProTaper group, when the middle level displayed the most removal, the coronal level showed much higher removal than the mid-root level, while the apical level often exhibited the highest removal. Conclusion: ProTaper retreatment files outperformed MTwo, D-RaCe, and R-Endo among the four groups in terms of removing root canal filling material. However, none of the experimental groups removed gutta-percha completely from root canals.

A study protocol of assessing grass root level health care service delivery system in Wardha District, Maharashtra

Background One of the six elements that constitute the framework of the World Health Organization System is the delivery of health care. To tracks the development of healthcare service delivery, it is vital to focus on its dimensions. The objective of the current learning is to evaluate the quality of healthcare provided at the lowest level in the Wardha District. Methods A community-based cross-sectional study will be conducted in the rural area around all the sub-centers of Wardha District. A semi-structured questionnaire will be used to assess the sociodemographic profile and associated factors, namely, service delivery, service provision, and facility assessment. Study implications This study will help formulate policies that will inculcate grass-root-level health care services to gain insight into how much services need to be improved and its implications for everyone in the community. Its significance in public health will pave the way for service screening and testing of healthcare delivery systems. Additionally, it will show that the system for delivering healthcare performs better. Future research should concentrate on identifying localized deficiencies and developing console indicators to estimate healthcare delivery systems objectively.

Assessment of happiness among ASHAs, the grass root level health workers in post-COVID era in Eastern India: a cross-sectional study

Background: The happiness of healthcare professionals is said to be positively affecting the quality of health care and the services provided by them. Presently, our country and its health care has been recovering from the brunt of COVID pandemic. Amid these changing circumstances, this study intends to assess the happiness among the key grassroot level workers, ASHAs in the post-COVID era and the factors affecting their happiness, as happiness is often put forward as one of the driving forces to peoples’ choices and actions. Methods: A modified short version of Oxford happiness questionnaire was used to assess the happiness among the ASHAs selected through multistage sampling and interviewed to assess the facilitators and barriers to their happiness. Results: Of the 112 ASHAs interviewed, 61.6% were happy, while 38.4% were unhappy. The variables like having commitment to work, mental alertness and ability to find beauty in many natural things had universal agreement, while not feeling healthy, or whether they find time for everything wanted have disagreement. Almost 87.5% felt they were not especially control of their lives and 41% were not being well satisfied with everything in life. The factors facilitating happiness were professional pride, altruism, quality of life, and major barriers identified were inadequate rest, imbalance in work-life, family issues, etc. Conclusions: Positive reinforcement in terms of better workplace environment, time management skill enhancement, to strike a better work-life balance to ensure a happier version of themselves.

An Organized Management Information System :A Descriptive Study from the Dash Board of NREGAsoft

All public funded programmes need to ensure transparency and thoroughness in its implementation. If it cannot follow the characteristics, may lead to failure in its execution. For ensuring good governance with the help of technology and innovation it is mandatory to follow the basic rule and regulations implied in the programme. Now it became the standard operating procedure in the present scenario. The largest public funded programme in the world, MGNREGA, is fit up with technology and point of order. The study tries to see that the employment guarantee programme is not only meant for the rural, unskilled marginalised community’s livelihood enhancement, but to empower them in the digital world. Here in this study, tries to describe and relate the high-end technology with a grass root level employment guarantee programme. It is, then deemed to be the best model for all forthcoming government funded programmes.

Pesticide residues in ornamental plants marketed as bee friendly: Levels in flowers, leaves, roots and soil

Ornamental plants rich in pollen and nectar are often marketed as “pollinator-friendly” by flower retailers. However, even though the plants are attractive from a foraging perspective, i.e pollen and nectar rich, bees and other pollinating insects could be at risk from exposure of pesticide residues on the plants or from pesticide used during production. Pesticides used in ornamental plant production could lead to environmental emissions both during cultivation, at retailer displays and when planted in gardens by the consumers. This study aims to investigate what pesticides that are used in the production of perennial ornamental plants sold in Sweden and if the residues could pose a risk for wild pollinators. We analyze an array of 536 pesticides in whole flowers, leaves, roots and soil of 54 individual (46 had flowers) perennial plants specifically marketed as “bee friendly”. In addition, seeds from 65 seed bags were analyzed for the same pesticides. Our result show for the first time the distribution of pesticide residues between flowers, leaves, roots and soils of ornamental plants. We also show that all ornamental plants analyzed contained at least one pesticide, and that some samples contained up to 19 different substances.

Metabolomics reveals how spinach plants reprogram metabolites to cope with intense stress responses induced by photoaged polystyrene nanoplastics (PSNPs)

While land-based sources have been recognized as significant long-term sinks for micro- and nanoplastics, there is limited knowledge about the uptake, translocation, and phytotoxicity of nanoplastics (NPs) in terrestrial environments, especially aged NPs. In this study, we investigated the impact of aged polystyrene nanoplastics (PSNPs) on the uptake, physiology, and metabolism of spinach. Our findings revealed that both pristine and aged PSNPs can accumulate in the roots and subsequently translocate to the aboveground tissues, thereby influencing numerous key growth indicators in spinach plants. A more pronounced impact was observed in the treatment of aged PSNPs, triggering more significant and extensive changes in metabolite levels. Furthermore, alterations in targeted pathways, specifically aminoacyl-tRNA biosynthesis and phenylpropanoid biosynthesis, were induced by aged PSNPs, while pristine PSNPs influenced pathways related to sulfur metabolism, biosynthesis of unsaturated fatty acids, and tryptophan metabolism. Additionally, tissue-specific responses were observed at the metabolomics level in both roots and leaves. These results highlight the existence of diverse and tissue-specific metabolic responses in spinach plants exposed to pristine and aged PSNPs, providing insights into the mechanisms of defense and detoxification against NP-induced stress.

Role of organic and inorganic amendments on physiological attributes of germinating pea seedlings under arsenic stress

There are scarce data regarding the effects of soil amendments on biophysicochemical responses of plants at the early stages of growth/germination. This study critically compares the effects of ethylene-diamine-tetra-acetic-acid (EDTA) and calcium (Ca) on biophysicochemical responses of germinating pea seedlings under varied arsenic levels (As, 25, 125, 250 µM). Arsenic alone enhanced hydrogen peroxide (H2O2) level in pea roots (176%) and shoot (89%), which significantly reduced seed germination percentage, pigment contents, and growth parameters. Presence of EDTA and Ca in growth culture minimized the toxic effects of As on pea seedlings, EDTA being more pertinent than Ca. Both the amendments decreased H2O2 levels in pea tissues (16% in shoot and 13% in roots by EDTA, and 7% by Ca in shoot), and maintained seed germination, pigment contents, and growth parameters of peas close to those of the control treatment. The effects of all As-treatments were more pronounced in the pea roots than in the shoot. The presence of organic and inorganic amendments can play a useful role in alleviating As toxicity at the early stages of pea growth. The scarcity of data demands comparing plant biophysicochemical responses at different stages of plant growth (germinating vs mature) in future studies.

Anatomy of the pudendal nerve in clinically important areas: a pictorial essay and narrative review.

The pudendal nerve is an anatomical structure arising from the ventral branches of the spinal roots S2-S4. Its complex course may be affected by surrounding structures. This may result in irritation or entrapment of the nerve with subsequent clinical symptoms. Aim of this study is to review the anatomy of the pudendal nerve and to provide detailed photographic documentation of the areas with most frequent clinical impact which are essential for surgical approach. Major medical databases were searched to identify all anatomical studies investigating pudendal nerve and its variability, and possible clinical outcome of these variants. Extracted data consisted of morphometric parameters, arrangement of the pudendal nerve at the level of roots, formation of pudendal nerve, position according to sacrospinal and sacrotuberal ligaments and its terminal branches. One female cadaver hemipelvis was dissected with common variability of separate course of inferior rectal nerve. During dissection photodocumentation was made to record course of pudendal nerve with focus on areas with recorded pathologies and areas exposed to iatrogenic damage during surgical procedures. Narrative review was done to provide background for photodocumentation. Unique photos of course of the pudendal nerve was made in areas with great clinical significance. Knowledge of anatomical variations and course of the pudendal nerve is important for examinations and surgical interventions. Surgically exposed areas may become a site for iatrogenic damage of pudendal nerve; therefore, unique picture was made to clarify topographic relations.

AN ANALYTICAL STUDY OF THE PERFORMANCE OF PANCHAYATS IN TRIPURA: MAJOR INITIATIVES AND ACHIEVEMENTS

The introduction of the 73rd Constitutional Amendment to the Constitution of India brought a new beginning and positive changes to Indian democracy. It has strengthened the concept of democracy by ensuring the decentralization of power at the grass roots level. The creation of the Three Tier Panchayat System was a land mark step giving voice to the rural people in the process of governance and democratic development planning. In conformity with this Act, in 1993, the Government of Tripura brought forward the Tripura Panchayats Act. The present paper aims to analyse the performance of the Panchayats of Tripura and the contribution of PRIs in developing the rural areas of Tripura.

Evaluation of Morpho-Physiological Traits of Oat (Avena sativa L.) under Drought Stress

The increase in intensity and frequency of drought due to global climate change has increased the urgency of developing crop cultivars suitable for dry environments. Drought tolerance is a complex trait that involves numerous physiological, biochemical, and morphological responses. A better understanding of those mechanisms is critical to develop drought tolerant cultivars. In this study, we aimed to understand the morphophysiological changes at the shoot and root levels in response to drought stress of ten oat genotypes with diverse root morphological characteristics. Twenty-one-day old plants were subjected to drought stress in a greenhouse by withholding water for two weeks. Several characteristics including chlorophyll content, relative water content (RWC), stomatal conductance, stomata number, shoot dry weight (SDW), root dry weight (RDW), root-to-shoot biomass ratio (RSR), root length, root area, and root volume were measured on well-watered, and drought-stressed plants. Grain yield was evaluated by continuing the drought treatment with a drying and rewatering cycle every 15 days until physiological maturity. The water regime had a significant impact on all traits evaluated. A significant interaction between genotype and water treatment was observed for RWC, chlorophyll content, stomatal conductance, stomata number, and grain yield but not for root traits, suggesting that the root system of all genotypes responded similarly to drought stress. Hayden, the cultivar with the lowest reduction in grain yield from the drought treatment, was among the genotypes with the lowest reduction in RWC and chlorophyll content but with a sharp decrease in stomata number, thus indicating that regulating the plant water status and maintaining the photosynthesis level are important for oat plants to maintain grain yield under drought stress. The size of the root system was not correlated with grain yield under drought, but the RWC and grain yield were significantly correlated under drought, thus suggesting that maintaining the RWC is an important characteristic for oat plants to maintain yield under drought stress.

Multiplier flock scheme in Barbari goats: An entrepreneurship model for in situ breed conservation and improvement

Barbari is a most preferred breed for commercial goat farming-under intensive management. However, pure-bred Barbari goats; especially buck’s availability are meager due to indiscriminate castration which resulted in stagnation of genetic improvement and breed dilution. Multiplier Flock Scheme, an integrated genetic improvement model was initiated at ICAR-CIRG, Makhdoom to cater the need of pure-bred and high merit goats and to promote commercial goat farming. Trained farmers with adequate housing and know-how were registered under this scheme and they were provided a foundation stock of Barbari goat to multiply with all technical support. Currently, 50 such goat farms exist in India with flock size of 50 to 350 goats. Data was collected on animal performance and economic attributes from eight such farms. The least squares means of body weight of Barbari kids at birth, 3, 6, 9 and 12 months of age were 1.58, 7.22, 14.54, 20.01 and 25.76 kg, respectively. The average 60 and 90 days milk yield were 45.23 and 66.28 litre. The pre-weaning, post-weaning (3-12 month) and adult mortality were 9.03, 4.33 and 5.40% of flock strength. The net profit per goat/year ranged from ₹3800 to ₹13000 under various business models and the benefit:cost ratios ranged from 1.50 to 2.42 with mean and median value of 1.94 and 2.00, respectively. Present study concluded that multiplier flocks is efficient breeding model for improvement, conservation of goat breeds, promoting scientific goat farming at grass root level and very helpful to policymakers for small ruminant development.