Zinc Levels Research Articles

Association Between Dietary Intake After Roux-en-Y Gastric Bypass Surgery and Antioxidant/inflammatory Status: A 6-Month Pilot Prospective Cohort Study.

Adipose tissue can increase levels of inflammation and oxidative stress, which explains the relationship between obesity and many chronic diseases. Weight loss, changes in adipose tissue metabolism, and dietary nutrient intake changes following bariatric surgery could affect a number of oxidative- and inflammation-related factors. Therefore, this study aimed to assess the potential relationship between dietary intake and inflammatory/antioxidant markers in the 6months following Roux-en-Y gastric bypass surgery (RYGB). This pilot prospective cohort study included 45 patients with severe obesity who underwent RYGB. The patients were assessed at three different time points: baseline, 3 months, and 6 months post-surgery. Throughout the study, dietary intake data, levels of total antioxidant capacity (TAC), NF-κB, and serum levels of certain micronutrients were measured three times. Dietary macro- and micronutrient intake data were obtained three times throughout the study using the 24-h food recall questionnaire. The analysis of dietary indices in the present study found a significant positive correlation between the dietary intake of zinc, copper, MUFA, and serum TAC levels. It also revealed a significant inverse correlation between serum levels of NF-κB with vitamin E and PUFA intake. Additionally, there was a significant positive association between the amount of dietary carbohydrates and saturated fatty acids intake and the levels of NF-κB. Furthermore, within 3 to 6 months after the surgery, patients experienced an increase in serum levels of TAC, ferritin, vitamin D3, vitamin B12, and folate. However, there was a decrease in serum levels of NF-κB, zinc, and copper. Weight loss and nutritional status may potentially impact oxidative stress and inflammation levels within 6months following RYGB surgery. Further research is necessary to comprehensively investigate the different facets of this correlation and elucidate the precise underlying mechanism.

Assessment of Heavy Metal Contamination in the Sediments and Soils in the City of Dubai based on the Geoaccumulation Index

This research assesses heavy metal contamination in surface sediments and soils in Dubai using the geoaccumulation index model. Soil and sediment samples were collected from 19 sites across Dubai, with sampling conducted twice to detect variations in heavy metal concentrations. Eight heavy metals—Silver (Ag), Cadmium (Cd), Chromium (Cr), Copper (Cu), Manganese (Mn), Nickel (Ni), Lead (Pb), and Zinc (Zn)—were analyzed for their environmental impact and abundance.Results showed that the soil was highly polluted with Silver (Ag). Nickel (Ni) concentrations ranged from Unpolluted to Moderately Polluted. Chromium (Cr) levels indicated Unpolluted to Moderately Polluted status, except in Al-Marmoum Heritage Village, Jumeirah Lakes, Al-Mamzar Open Beach, and Remram, which showed higher contamination. Cadmium (Cd) levels varied, with some sites Unpolluted and others Unpolluted to Moderately Polluted. Copper (Cu), Manganese (Mn), Lead (Pb), and Zinc (Zn) levels indicated unpolluted status.Area-wise, Jumeirah Lakes, excluding silver contamination, was generally Unpolluted. Dubai Creek exhibited the highest geoaccumulation index for several metals, including Silver, Cadmium, Chromium, Nickel, and Zinc.

Hydrogen-assisted recycling of Nd-Fe-B magnets from the end-of-life audio products

The transition towards green and sustainable technologies has significantly increased the demand for a subset of raw materials known as critical elements. Rare earth elements with their main use in Neodymium-Iron-Boron magnets (NdFeB) play a key role in clean energy technologies including electric vehicles and wind turbine generators. They are also a key component in electronic devices including mobile phones, hard disk drives, and loudspeakers. Here, we build on previous knowledge of the recycling of NdFeB magnets from hard disk drives, using a hydrogen process called HPMS (Hydrogen Processing of Magnet Scrap). This study investigates a new scrap stream from loudspeakers, specifically from vehicles and flat-screen TVs. The extracted magnets from loudspeakers typically had grades of N30/N33 with relatively low coercivity values. The interactions of the extracted magnets with hydrogen were monitored by gravimetric and thermal analyses. The thermodynamics and kinetics of the hydrogenation reaction appear to differ significantly based on their chemical composition, chemical homogeneity, coating state, and surface condition of the magnets. Overall, the HPMS process was demonstrated to successfully produce demagnetised hydrogen decrepitated powder at room temperature under 2 bar of hydrogen, in a commercially viable timeframe (approx. 4 h). Zinc was found to be the dominant coating material which peeled away during the HPMS process. The zinc content of the NdFeB alloy powder could be reduced after the hydrogen decrepitation by sieving. The remaining level of zinc had no noticeable impact on the magnetic properties of the recycled magnets. The particle size of the recycled alloy powder could be reduced to below 7 µm by ball milling and knife milling but with an increase in the oxygen level, limiting its sintering ability. Sintered magnet from the recycled alloy powder demonstrated similar magnetic properties (Br: 1.06 T, HcJ: 1240 kA/m, and (BH)max: 220 kJ/m3) after blending with 5 wt% of NdH3, making vehicles and flat-screen TV speakers ideal sources for a recycled magnet.

Zinc Deficiency in Critically Ill Patients: Impact on Clinical Outcome.

Background Zinc is a trace element essential for the normal functioning of many vital enzymes and organ systems. Studies examining the rates and degrees of zinc deficiency and its consequences in patients with critical illnesses remain scarce. Materials and methods This is a prospective observational study assessing zinc deficiency in critically ill adult patients admitted to a tertiary care intensive care unit (ICU) and its impact on clinical outcomes. Patients were divided into those with normal (≥ 71 µg/dl) and low (≤ 70 µg/dl) zinc levels. Zinc-deficient patients were further divided into mild, moderate, and severe zinc deficiency groups based on zinc levels of 61-70 µg/dl, 51-60 µg/dl, and below 51 µg/dl, respectively. The primary outcome assessed was ICU mortality, and the secondary outcomes were ICU length of stay (LOS), duration of invasive mechanical ventilation (IMV), acute kidney injury (AKI) at admission, need for non-invasive ventilation (NIV), renal replacement therapy (RRT), or vasopressors during the course of the ICU. Other parameters compared included APACHE (Acute Physiology and Chronic Health Evaluation) II, SOFA (Sequential Organ Failure Assessment) score on day 1, and levels of lactate, procalcitonin, calcium, magnesium, phosphate, and serum albumin. The study also compared the mean zinc levels in patients with low and high SOFA scores (scores up to 7 vs. 8 and above) and low and high APACHE II values (scores up to 15 vs. 16 and above). Results A total of 50 patients were included, of whom 43 (86%) were zinc deficient. Mortality in zinc-deficient and normal zinc-level patients was 33% and 43%, respectively (p = 0.602). Patients with zinc deficiency were also older (mean age 69 vs. 49 years, p = 0.02). There was no difference in secondary outcome parameters, except for more zinc-deficient patients needing RRT. Twenty-six of the zinc-deficient patients had severe zinc deficiency, ten moderate, and seven mild (p = 0.663). ICU mortality was approximately 42%, 10%, and 29% in the severe, moderate, and mild deficiency groups, respectively (p = 0.092). Zinc levels were similar between those with low and high APACHE II scores (mean 47.9 vs. 45.5 µg/dl, p = 0.606) as well as between low and high SOFA scores (mean 47.8 vs. 45.7 µg/dl, p = 0.054). Conclusion The present study suggests that zinc deficiency is very common in critically ill patients but does not correlate with their severity of illness, nor does it lead to a poorer outcome in these patients. However, further studies with a larger cohort of patients would be required to make definitive conclusions.

Accumulation of Heavy Metals and Their Genotoxic Potential in Medicinal Plant Verbacsum speciosum Schrad.

Background: Nowadays, the contamination of soil, water, and plants by heavy metals (HMs) presents a notable environmental problem. Methods: Lead (Pb) and zinc (Zn) levels in soil and Verbacsum speciosum populations were measured using atomic absorption spectroscopy, and meiosis in pollen mother cells (PMCs) was examined through the squash technique to evaluate genotoxic effects. Results: The results showed that Pb and Zn concentrations in the soil and, roots, and aboveground portions of all Verbacsum speciosum populations within the mining area exceeded permissible thresholds significantly. Particularly, the contaminated soil displayed average Pb and Zn concentrations of 3527.4±0.7 and 1671.4±0.5 mg/kg, respectively. The roots of Verbacsum speciosum plants closest to the mine exhibited the highest levels of Pb and Zn, measuring 204±0.05 mg/kg and 570±0.16 mg/kg, respectively. Additionally, the above-ground parts of the plants showed Pb and Zn concentrations of 312±0.12 mg/kg and 519±0.17 mg/kg, respectively. Moreover, the transfer factor (TF) for both Pb and Zn was found to be above one, indicating substantial accumulation of these metals in the above-ground portions. The presence of Pb and Zn also resulted in abnormalities during meiosis. As the distance from the mine increased, a decrease in the occurrence of meiosis abnormalities and an increase in the meiotic index (MI) were observed. Conclusion: These results highlight the potential risks to human health posed by industrial wastewater and the natural presence of HMs in soil. The ability of these metals to accumulate in plants and interfere with their meiosis underscores the importance of addressing and mitigating these hazards.

The Association Between Psoriasis and Trace Element Serum Levels and Dietary Intake: Results from USA National Health and Nutrition Examination Survey 2011-2014.

Psoriasis is a common chronic inflammatory disease. However, trace elements are essential to biochemical processes of the skin, it is suspected that the trace elements are vital in the pathogenesis of psoriasis. Our research is aimed to investigate the association between serum levels and dietary intake levels of selenium, zinc, and copper with psoriasis. In this cross-sectional study, we utilized the National Health and Nutrition Examination Survey data from 2011 to 2014 to examine the association between psoriasis and serum concentration and dietary intake of trace elements including copper, zinc, and selenium in the US individuals. Our research combined two cycles and weighted the data. Student's t-tests and χ2 test were used. Subgroup analyses and interaction tests were conducted by IBM SPSS Statistics 22 and EmpowerStats. This study indicates that the population with psoriasis has a lower dose of dietary intake selenium than the controls, and risk analysis showed that the men with selenium daily intake >150 mcg/day have a decreasing risk for psoriasis compared to those with daily intaking selenium <75 mcg/day. However, there are no differences on daily intake of selenium, zinc, and copper and serum levels of Zinc and Copper between psoriasis and healthy controls. The current study showed that the psoriasis group was significantly older with a bigger waist circumference, a higher education level, a higher ratio of people with smoke every day, and a higher ratio of people in USA and being non-Hispanic White. This cross-section study showed that a high selenium intake may benefit USA adults from psoriasis, especially for males. The social and cultural background and ethnic differences between the two groups influence the eating and living models, including the trace element intake. The national recommended dietary allowances (RDAs) might be considered to be modified with more reliable investigative clinical data and certain considering the social and cultural models.

Studying the impact of sulphur and zinc levels on the growth, yield, and quality of Indian mustard [Brassica juncea L).

Studying the impact of sulphur and zinc levels on the growth, yield, and quality of Indian mustard [Brassica juncea L).

Minerals and dietary fibre source snack made from Moringa leaves enriched with ginger

The findings from the 2021 Indonesian Nutritional Status Study reveal a substantial 24.4% prevalence of child stunting, emphasizing the need for diverse strategies to achieve the desired target. One such strategy involves ensuring the nutritional well-being of expectant mothers to prevent stunting. Moringa leaves are a rich source of essential nutrients. Incorporating Moringa leaf powder into catfish flour-based snacks can boost their protein and mineral content while overcoming any undesirable odors, though this application is currently limited to crackers. This study aimed to create snack products using Moringa leaves, such as tea, brownies, and pudding, with the addition of ginger to enhance dietary fiber and mineral content for pregnant women. The top formulations identified through sensory assessment are F1 tea, F1 brownies, and F2 pudding. These specific tea, brownies, and pudding variations boast dietary fiber content exceeding 3 grams and meet or exceed 15% of the recommended daily intake levels for iron and zinc for pregnant women, as stipulated by the nutrition label reference. As a result, they can be classified as wholesome snacks rich in dietary fiber, iron, and zinc.

Effect of different level of NPK, zinc and vermicompost on the soil health parameters and the yield of white maize (Zea mays L.) var. HM-12

Effect of different level of NPK, zinc and vermicompost on the soil health parameters and the yield of white maize (Zea mays L.) var. HM-12

Intergenerational Impact of Parental Zinc Deficiency on Metabolic and Redox Outcomes in Drosophila melanogaster.

Zinc deficiency is a common nutritional disorder with detrimental health consequences. Whether parental zinc deficiency induces intergenerational effects remains largely unknown. We investigated the effects of a combined maternal and paternal zinc deficiency on offspring's metabolic outcomes and gene expression changes in Drosophila melanogaster. The parent flies were raised on zinc-deficient diets throughout development, and their progeny were assessed. Offspring from zinc-deprived parents exhibited a significant (p < 0.05) increase in body weight and whole-body zinc levels. They also displayed disrupted glucose metabolism, altered lipid homeostasis, and diminished activity of antioxidant enzymes. Gene expression analysis revealed significant (p < 0.05) alterations in zinc transport genes, with increases in mRNA levels of dZIP1 and dZnT1 for female and male offspring, respectively. Both sexes exhibited reduced dZnT35C mRNA levels and significant (p < 0.05) increases in the mRNA levels of DILP2 and proinflammatory markers, Eiger and UPD2. Overall, female offspring showed higher sensitivity to parental zinc deficiency. Our findings underscore zinc's crucial role in maintaining health and the gender-specific responses to zinc deficiency. There is the need for further exploration of the underlying mechanisms behind these intergenerational effects.

Genetic Causal Associations between Various Serum Minerals and Risk of Depression: A Mendelian Randomization Study.

Previous observational studies have discovered a connection between depression and mineral status. Confirming this potential connection is challenging due to confounding factors and potential reverse causality which is inherent in observational studies. We performed a Mendelian randomization (MR) analysis to estimate the causal association of serum minerals with depression. Leveraging summary-level data on depression, a genome-wide association study (GWAS) was applied. The data on serum minerals were collected from the FinnGen Biobank database. MR assessments representing causality were produced by inverse-variance weighted approaches with multiplicative random and fixed effects. Sensitivity analyses were performed to validate the reliability of the results. A noteworthy correlation emerged between serum zinc levels and reduced risk of depression. An odds ratio (OR) of 0.917 for depression associated with a one standard deviation increase in serum zinc levels (OR = 0.968; 95% CI = 0.953-0.984, p = 1.19 × 10-4, random effects model inverse variance weighted (IVW)); (OR = 0.928; 95% CI = 0.634-1.358, p = 0.766, MR Egger). Sensitivity assessments supported this causation. However, the risk of depression did not exhibit an association with other minerals. In summary, a higher zinc concentration is causally associated with a reduced depression risk. This MR outcome may assist clinicians in the regulation of specific mineral intake, particularly for high-risk patients with serum zinc deficiencies.

Circulating zinc levels and cardiometabolic risk-related variables in adults

Introduction. Altered serum zinc levels, lower and higher than values in healthy controls, have been observed in individuals affected by non-communicable chronic diseases. However, to date, studies describing potential determinants of zinc levels in general populations free of chronic diseases appear to be limited. Objective. To evaluate whether nutrient intake, biochemical and clinical measures, lifestyle, and family history of cardio-metabolic diseases are independently associated with zinc levels in apparently healthy individuals. Materials and methods. We evaluated 239 healthy subjects. Serum zinc was measured via flame atomic absorption spectrometry, and the remaining biochemical markers were assessed using enzymatic colorimetric methods. Standard techniques were employed to quantify waist circumference, height, and weight. Body fat was measured via bioimpedance, and blood pressure was measured using digital sphygmomanometers. We applied a survey to record the personal and family history of non-communicable chronic diseases, and nutrient intake was estimated using the 24-hour recall method. Results. Women had lower serum zinc levels than men. In multivariate analyzes, total fat intake (β = -0.15; standard error = 0.03; p < 0.001), plasma log-triglycerides (β = -10.18; standard error = 3.9; p = 0.010), and female gender (β = -6.81; standard error = 3.3; p = 0.043) were significant predictors for serum zinc levels. Zinc intake was not significantly related to serum zinc in univariate and multivariate analyses. Conclusions. Variables related to cardiometabolic risk, such as plasma triglyceride levels and total fat intake, were associated with serum zinc levels in individuals without a diagnosis of chronic or infectious/inflammatory diseases. Further studies are required to confirm our findings and to evaluate possible biological mechanisms for these relationships.

Factors Causing Stunting In Toddlers In West Sumatra And Its Relationship With Sanitation And Environmental Hygiene : Literatur Review

One of the health problems that occurs in the world is stunting. Stunting or what is commonly known as short toddlers is a condition where toddlers are less tall compared to their age. West Sumatra Province is ranked 17th out of 34 provinces that experience stunting with a prevalence of stunting in toddlers (aged 24-59 months) of 36.2%, which is higher than the national prevalence, namely 30.8%. Stunting can also occur due to direct factors of stunting such as maternal nutrition during pregnancy, toddler nutrition and disease infections. Apart from direct factors, there are also indirect factors that can occur from various aspects, one of which is water, sanitation and hygiene (WASH). This research uses a literature study method using PICO. The research results obtained were that there was a relationship between the LBW factor (lower baby weight) and the incidence of stunting in toddlers, three articles were obtained. Two articles were found regarding the relationship between exclusive breastfeeding and MP-ASI. On the relationship between parenting styles, four articles were found. Three articles were found regarding the relationship between sanitation and the environment. Three articles were found regarding the relationship between height and height. One article was found regarding the relationship between zinc levels. On the relationship between mother's work, one article was found. Regarding the history of infectious diseases, one article was found. One article was found regarding the relationship between the age of pregnant women and the incidence of stunting in toddlers. From the conclusion above regarding the relationship between environmental sanitation and hygiene on stunting among toddlers in West Sumatra, the most common one is parenting patterns in children.Keyword : abstract; nutrition; words; research

Risk quantification as an epidemiological analysis strategy: Analysis and application to bud rot in oil palm

AbstractBud rot (BR), caused by Phytophthora palmivora, limits growth and development of oil palms in the American continent, particularly in Colombia. Due to the absence of systematic epidemiological analyses and determination of risk factors associated with BR, this study aimed to employ deterministic mathematical models and frequentist and Bayesian statistical methods to quantify the genetic response and edaphoclimatic variables as risk indicators of BR. From 2011 to 2014, the severity of BR in oil palm crops was recorded monthly in two locations: Tumaco (hot spot) and Villavicencio (cold spot), determining the edaphoclimatic variables at each site. Using the area under the disease progress stairs curve, temporal models were applied to determine the rate of disease development (R0) to quantify risk at locality and genotype levels. Subsequently, the observed intensity and severity levels of BR were adjusted to models such as survival curves, Cox proportional hazard risk and transition probabilities, or Markov states, with the aim of quantifying and characterizing risk factors associated with genotype and edaphoclimatic variables at each location. The risk in Tumaco was three times higher than in Villavicencio, and the R0 values were differential by genotype, with Tenera more susceptible than Hybrids. Moreover, the risk of BR increased when periods of 2–3 months occurred with successive instances of precipitation and relative humidity greater than 150 mm/month and 90%, respectively, and when manganese and zinc levels were below optimal. This approach allowed us to characterize epidemiological factors that cause plant diseases, allowing quantification of the risk of BR.

Assessment of urban air quality in Abidjan in terms of trace metals (copper, lead, zinc) by arborescent vegetation: Case of the species Hibiscus tiliaceus rubra.

Urban air quality is closely linked to human activities. Policies aimed at reducing or monitoring this form of pollution therefore have a dual benefit for health and the environment. Biomonitoring of air quality is one possible scientific approach. In this study, the woody species Hibiscus tiliaceus rubra was used as a biomonitor of air quality in the city of Abidjan. The leaves of the woody species were used to quantify the bioaccumulation of three trace metals: copper, lead and zinc. The assessment was carried out on five main road sections: "Adjamé-Cocody", " Adjamé-Yopougon", "Cocody-Bingerville", abobo-Anyama” and " Adjamé-Plateau". The results obtained show that the content of these trace metals varies according to the road. High levels of copper and zinc and very low levels of lead were initially found in the leaves of the species. The Adjamé-Cocody axis and the Adjamé-Yopougon axis recorded the highest levels of lead. The Adjamé-Plateau axis remains the least contaminated, with relatively low levels of lead.

Retraction Note: Dopaminergic Neuronal Death in Substantia Nigra Associates with Serum Levels of Total Bilirubin, Selenium, and Zinc: Evidences from 6-Hydroxydopamine Animal Model of Parkinson's Disease.

Retraction Note: Dopaminergic Neuronal Death in Substantia Nigra Associates with Serum Levels of Total Bilirubin, Selenium, and Zinc: Evidences from 6-Hydroxydopamine Animal Model of Parkinson's Disease.

Hair zinc level and autism spectrum disorder in children

Background Autism spectrum disorder (ASD) is one of the most common neurodevelopmental disorders. In children with ASD, the neurodevelopmental and behavioral disorders are characterized by impaired quality of interaction, communication, and social imagination, with limited interest and repetitive behavior. Various studies have found that the mean zinc level is lower in children with ASD than in children without ASD, especially in the low functioning autism. Objective To compare hair zinc level in children with and without ASD. Methods This case-control study included children with ASD and controls without ASD. Subjects were children under 5 years old who came to Prof I.G.N.G. Ngoerah Hospital and Masadini Clinic in Denpasar. Hair zinc cut-off level was determined by the area under curve (AUC) based on the receiver operating characteristic (ROC) curve. Results A total of 128 subjects consisted of 64 cases and 64 controls, with a mean age of 4 (SD 0.8) years. Most subjects were male (76%); 82.3% were well-nourished. The mean maternal age at delivery was 28.82 (SD 3.2) years. Subjects’ mean hair zinc level was 87.9 (SD 231.1) ?g/g. Bivariate analysis with Chi-square test revealed that children with hair zinc concentration of &lt;33.88 ?g/g were 22.19 times more likely to have ASD than those with higher zinc levels (OR 22.19; 95%CI 8.02 to 42.09; P&lt;0.001). Conclusion Low hair zinc level is more likely to occur in children with ASD than in children without ASD.

Consumption Of Zinc (Zn) And Iron (Fe) And Hemoglobin Levels In Female Students Of Senior High School 1 Gianyar

Young women are susceptible to nutritional problems, one of which is anemia. The cause of anemia is the lack of consumption of macro and micronutrients, such as iron and zinc. The problem of anemia in adolescent girls will cause adverse effects such as causing babies born with low weight, stunting babies, and high prenatal mortality. The purpose of this study was to determine the relationship between zinc and iron consumption and hemoglobin levels in high school students Negeri 1 Gianyar. The type of data in this study is analytical using a cross sectional design. The population in this study was grade 11 and 12 students with a sample of 60 people selected by random sampling. Data on zinc and iron consumption were obtained using a 24-hour food recall questionnaire processed using the 2007 Nutri Survey program, and hemoglobin levels were obtained by digital multicheck method, namely with GCHb Easy Touch. Data were analyzed using bivariate analysis using the Spearman rank test. The results showed the level of zinc and iron consumption was still lacking. The average consumption of zinc and iron after the data was processed was zinc consumption which was 4.3 mg and iron consumption was 4.5 mg.

Gelatinization and fermentation synergy: investigating the protein digestibility, mineral bioaccessibility and microstructural transformations of black mash beans through Saccharomyces cerevisiae and Lactobacillus spp

ABSTRACT This study explored the nutritional qualities of black mash bean flour impacted by fermentation, gelatinization and their combination. Protease activity, in vitro protein digestibility (IVPD), and protein solubility were evaluated for both fermented and unfermented black mash bean flour samples. Interestingly, when compared to fermented samples and gelatinized mash bean flour (GMBF), raw mash bean flour (RMBF) showed the highest protein solubility. Due to enzymatic activity and protein hydrolysis, fermentation with Lactobacillus E14 and Saccharomyces cerevisiae MK-157 enhanced protein solubility. Prolonged fermentation timeframes were positively correlated with protease activity and IVPD, suggesting the degradation of complex proteins. The highest levels of IVPD (90.12%) and protease activity (5546.78 U/g) were detected in GMBF fermented by S. cerevisiae MK-157, indicating the impact of fermentation on protein breakdown. The Lactobacillus E14-fermented RMBF exhibited 5521.45 U/g of protease activity and 87.54% IVPD. The mineral content of the fermented samples was substantially greater than that of the unfermented GMBF. The increased calcium, magnesium, potassium, sodium, iron, zinc, and copper levels for the GMBF fermented by S. cerevisiae MK-157 indicated that fermentation facilitated the release of minerals from chelated compounds. Microscopic examination revealed higher protein quantities in the fermented flour as well as hydrolyzed and broken starch granules embedded in the protein matrix. Large mash bean proteins were shown to be proteolyzed during fermentation into smaller peptides by SDS PAGE. Storage proteins were extensively broken down during fermentation with S. cerevisiae MK-157, whereas Lactobacillus E14 displayed a more focused pattern of hydrolysis. The nutritional profile of black mash bean flour was improved by fermentation with Lactobacillus E14 and S. cerevisiae MK-157.

Serum Folate, Red Blood Cell Folate, and Zinc Serum Levels Are Related with Gestational Weight Gain and Offspring's Birth-Weight of Adolescent Mothers.

Gestational weight gain below or above the Institute of Medicine recommendations has been associated with adverse perinatal and neonatal outcomes. Very few studies have evaluated the association between serum and red blood cell folate concentrations and gestational weight gain in adolescents. Additionally, zinc deficiency during pregnancy has been associated with impaired immunity, prolonged labor, preterm and post-term birth, intrauterine growth restriction, low birth weight, and pregnancy-induced hypertension. The purpose of our study is to evaluate the association between serum concentrations of zinc, serum folate, and red blood cell folate, with the increase in gestational weight and the weight and length of the newborn in a group of adolescent mothers from Mexico City. In our study, 406 adolescent-neonate dyads participated. The adolescents' median age was 15.8 years old. The predominant socioeconomic level was middle-low (57.8%), single (57%), 89.9% were engaged in home activities, and 41.3% completed secondary education. Excessive gestational weight gain was observed in 36.7% of cases, while insufficient gestational weight gain was noted in 38.4%. Small for gestational age infants were observed in 20.9% of the sample. Low serum folate (OR 2.1, 95% CI 1.3-3.3), decreased red blood cell folate (OR 1.6, 95% CI 1.0-2.6), and reduced serum zinc concentrations (OR 3.3, 95% CI 2.1-5.2) were associated with insufficient gestational weight gain. Decreased serum zinc levels (OR 1.2, 95% CI 1.2-3.4) were linked to an increased probability of delivering a baby who is small for their gestational age. Low serum folate, red blood cell folate, and serum zinc concentrations were associated with gestational weight gain and having a small gestational age baby. Both excessive and insufficient gestational weight gain, as well as having a small gestational age baby, are frequent among adolescent mothers.