Letters17 July 2012Adding Systematic Family History Enquiry to Cardiovascular Disease Risk Assessment: Clinical Utility in Primary CareJohn Robson, MD, Julia Hippisley-Cox, DM, and Peter Brindle, MDJohn Robson, MDFrom Centre for Health Sciences, Queen Mary's School of Medicine and Dentistry, London E1 2AT, United Kingdom; University of Nottingham, Nottingham NG7 2RD, United Kingdom; and Avon Primary Care Research Collaborative, Bristol BS1 3NX, United Kingdom.Search for more papers by this author, Julia Hippisley-Cox, DMFrom Centre for Health Sciences, Queen Mary's School of Medicine and Dentistry, London E1 2AT, United Kingdom; University of Nottingham, Nottingham NG7 2RD, United Kingdom; and Avon Primary Care Research Collaborative, Bristol BS1 3NX, United Kingdom.Search for more papers by this author, and Peter Brindle, MDFrom Centre for Health Sciences, Queen Mary's School of Medicine and Dentistry, London E1 2AT, United Kingdom; University of Nottingham, Nottingham NG7 2RD, United Kingdom; and Avon Primary Care Research Collaborative, Bristol BS1 3NX, United Kingdom.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-157-2-201207170-00019 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:We read the recent article by Qureshi and colleagues (1) with interest. We agree that a positive family history of ischemic heart disease in a first-degree relative younger than 60 years has a marked impact on future risk for major cardiovascular disease (1). In the United Kingdom, we developed QRISK2 (www.qrisk.org) (2), a new algorithm for cardiovascular risk prediction derived from 10.9 million person-years. It established that, for both men and women in all major ethnic groups and at all levels of social deprivation, positive family history is associated with an increased risk for cardiovascular disease. On ...