Utilize optional courses to modularize the scientific knowledge, and adopt various forms of teaching activities: such as watching the related videos, discussion between teachers and students and a variety of practical activities of college students so as to deepen college students' cognition to scientific knowledge, scientific method, scientific attitude, scientific spirit, science & technology and society and other aspects, thus enhancing the sense of social responsibility and improving students' scientific literacy. The level of scientific literacy of the public is the foundation of a nation's sustainable development. Reviewing the history of science, every major scientific discovery plays a very profound effect on the world view of humans and the development of society, and thus causes the thinking and understanding of the relationship between human and nature, between human and society, and between different persons. In the 21st century, as for the successful development that the society and the individual want, the scientific literacy of all the people and individuals is of vital importance. According to the unified deployment of the State Council and approved by the National Bureau of Statistics, China Association for Science and Technology conducted the investigation on the scientific quality of Chinese citizens from March to August, 2015. The scope of this investigation covers 31 provinces, autonomous regions and municipalities directly under the central government in mainland China. On September 19, 2015, China Association for Science and Technology published the results of the ninth investigation on the scientific quality of Chinese citizens: In 2015, the ratio of citizens with scientific quality in China reached 6.20%. According to the investigation, the levels of scientific quality of the young and middle-aged groups are higher, and the levels of scientific quality of the citizens aged 18 to 29 and 30 to 39 reached 11.59% and 7.16% respectively; most of the public use television, Internet and mobile Internet to obtain science & technology information [1]. The College students are a special social group. Improving the scientific literacy of college students has a direct relationship with the full implementation of the strategy of developing the country through science and education and the strategy of reinvigorating China through human resource development and the improvement of the competitiveness of comprehensive national strength. The course of Physics and Human Civilization established in our university is an optional course of scientific common sense education oriented to all the students. Through the exploration of the course content, teaching activities and others of this course, strengthen the students' scientific literacy.