Client Level Research Articles

The Effects of Experience and Client-Preferred Outcomes on Accountants' Complex Loss Valuation Judgments

ABSTRACTAccounting regulators, practitioners, and academics have all expressed concern that client preferences unduly influence accountants' judgment. This study builds on Ponemon (1995) by investigating the effects of client outcome preferences and experience levels on practicing forensic accountants' and auditors' complex loss valuation accounting judgments. Based on studies in motivated reasoning and accounting experience, we predict and find that experienced accountants have the capacity to ignore client-preferred outcomes when evaluating evidence. Specifically, when acting as an expert witness in a lawsuit involving a loss valuation dispute, forensic accountants and auditors both provide higher estimates of the plaintiff's damages when assuming the role of an expert retained by the plaintiff versus the court, unless participants possessed high experience. In addition, we find no difference in loss valuation judgments for practicing forensic accountants and auditors when both have high experience.

The Contours of Assessment: Considering Aspects that Influence Prediction Performance

ABSTRACT Actuarial assessments provide standardized scores for use in assigning client risk levels and identifying needs that can be matched with intervention. Drawing from an established theory and findings from tangential justice studies, the current study argues that using standardized instruments to predict recidivism everywhere is potentially problematic because the determination of conviction/incarceration has been shown to vary by jurisdiction and culture. Our exploratory analysis of a standardized assessment finds that when controlling for nation, age, and gender, heterogeneity in effect sizes is significantly reduced. Implications for the field of justice assessment are discussed.

Discovery of Novel Celastrol Derivatives as Hsp90-Cdc37 Interaction Disruptors with Antitumor Activity.

To develop novel and efficient heat shock protein 90-cell division cycle 37 (Hsp90-Cdc37) interaction disruptors, several lipophilic fragments were introduced into celastrol (CEL) to synthesize 48 new CEL derivatives. Among all the target compounds, 41 was screened with superior antiproliferative activity on related cancer cells (IC50: 0.41-0.94 μM) and 41 could decrease the level of the Hsp90-Cdc37 complex in A549 cells. The capability to disrupt the Hsp90-Cdc37 interaction was stronger than that of CEL. Furthermore, pull-down assay, UV assay, and molecular docking analysis all showed that 41 might disrupt the interaction of the Hsp90-Cdc37 complex by preferentially binding to Cdc37 in cancer cells. Further studies showed that 41 could significantly regulate the levels of Hsp90-Cdc37 clients, thereby inducing the apoptosis of cancer cells. Together, 41 is a novel Hsp90-Cdc37 disruptor by binding to Cdc37 (hydrogen bond and/or covalent bond). Our results may provide reference for the discovery of effective Hsp90-Cdc37 disruptors.

Natural Language Processing utilization in Healthcare

The significance of consolidating Natural Language Processing (NLP) techniques in clinical informatics research has been progressively perceived over the previous years, and has prompted transformative advances. Ordinarily, clinical NLP frameworks are created and assessed on word, sentence, or record level explanations that model explicit traits and highlights, for example, archive content (e.g., persistent status, or report type), record segment types (e.g., current meds, past restorative history, or release synopsis), named substances and ideas (e.g., analyses, side effects, or medicines) or semantic qualities (e.g., nullification, seriousness, or fleetingness). While some NLP undertakings consider expectations at the individual or gathering client level, these assignments still establish a minority. Here we give an expansive synopsis and layout of the difficult issues engaged with characterizing suitable natural and outward assessment strategies for NLP look into that will be utilized for clinical results research, and the other way around. A specific spotlight is set on psychological wellness investigate, a zone still generally understudied by the clinical NLP look into network, however where NLP techniques are of prominent importance. Ongoing advances in clinical NLP strategy improvement have been huge, yet we propose more accentuation should be put on thorough assessment for the field to progress further. To empower this, we give noteworthy recommendations, including an insignificant convention that could be utilized when announcing clinical NLP strategy improvement and its assessment.

Guided Imagery and Music on Anxiety of Mayor Operating Inpatients of Tangerang General Hospital

Background: The anxiety level of clients who will undergo major surgery is very influential on the smooth operation of the operation to be carried out. Actions of a nurse to overcome the anxiety that occurs on the client pre-operation are needed to be able to resolve the issue.
 Objective: This study aimed to look at changes in the patient’s anxiety level after guided imagery and music performed by nurses before the surgery performed.
 Methods: The research was used quasi-experimental with pretest-posttest control group design, sample collected used Quota Sampling method with total 38 sample divided into two group, the instrument of measuring the anxiety levelused(HARS-A)scale,whichthestatistictestusedWilcoxonSignedRankTestand Mann-Withney.
 Result: There was a decrease in the value of anxiety in the group given guided imagery and music with an average value of 7.50 (p-value:0.000), whereas there was a tendency to increase the value of anxiety in the control group with an average value of 6.00 (p-value:0.083). There were significant differences in the mean value between the intervention groups (14.03) and the control group (24.97) with p-value 0.001.
 Conclusion: Giving stimuli in the form of guided relaxation techniques can help reduce the level of anxiety in clients who will undergo surgery because it can help clients to distract their anxiety towards the operation process to other things of beautiful nature. The addition of music as one of the image transformation media can strengthen relaxation guidance to be able to reach the maximum level of relaxation that will have an impact on the ability to reduce their anxiety level

Changes in Social Participation of Persons Affected by Leprosy, Before and After Multidrug Therapy, in an Endemic State in Eastern India

Purpose: In general, multidrug therapy (MDT) completion rate and the change in disability levels before and after medical treatment are reported as outcomes in leprosy programmes. Changes in activity and social participation levels are rarely reported, possibly because the parameters are more difficult to measure. The study aimed to assess and evaluate the changes in social participation among leprosy-affected persons after completion of MDT. Method : An observational study was conducted among 108 newly-diagnosed leprosy- affected clients, who were registered at the Leprosy Referral Hospital in Champa, Chhattisgarh. Their disability levels pre- and post- MDT were assessed using the WHO Disability Grading, and their social participation level was assessed using the Participation Scale. Results : Of the 108 clients registered during the study period, 90 completed the full course of MDT and were included in the analysis. The majority of these 90 clients or 83% were multibacillary and 23% had Grade 2 disability at the time of diagnosis. At the end of MDT with steroids therapy for reaction and neuritis, the proportion of clients with no participation restriction increased from 76% to 93%. Clients with visible impairments had more restriction as compared to those with no deformity or no visible deformity, before and after MDT. Among those with visible impairments, 78% had mild to severe restriction before MDT and it declined to 26% on completion of treatment. Conclusion : Presence of Grade 2 disability at the time of diagnosis was significantly associated with participation restriction. MDT and steroid therapy for management of reaction and/or neuritis improves the participation level of leprosy-affected clients, suggesting that early detection and appropriate management would reduce their risk of participation restriction.

Antiretroviral service delivery at selected community pharmacies in Akwa Ibom State, Nigeria

Community-based Antiretroviral Therapy (CART) models have the potentials of providing better coverage, improving treatment uptake and producing good clinical outcome. This study was aimed at assessing the quality of antiretroviral service delivery at selected community pharmacies in Akwa Ibom State, Nigeria. A systematic cross-sectional study was carried out among HIV/AIDS clients devolved from hospitals to community pharmacies for antiretrovirals (ARV) refills. Community pharmacy with the highest number of clients was selected from each of the three senatorial districts of the State. A pre-tested questionnaire was used to obtain socio-demographic characteristics, medical and pharmaceutical data, devolvement information, quality of services received and level of clients’ satisfaction. Data collected were expressed as proportions and presented graphically. All the participants had viral load well controlled below 1000 cells/ml; and 99.43% were on Tenofovir/Lamivudine/Efavirenz (TDF/3TC/EFV) or Zidovudine/Lamivudine/Nevirapine (ZDV/3TC/NVP) while only 0.57% was on Abacavir/Lamivudine/Efavirenz (ABC/3TC/EFV). As response to reason for accepting devolvement, ‘shorter waiting time’ had the highest frequency while ‘proximity to residence’ had the lowest frequency. Drug pick-up time in hospital ranged from 4 to 10 h while in pharmacy, it ranged from 0 to 2 h. Majority of the participants (88.24-100.00%) from the different districts were satisfied with the different services received at the community pharmacies. ‘Very likely’ as likelihood of recommending the programme for others had the highest frequency. The clients were well controlled on the first line anti-retrovirals and were satisfied with the services received during medication refill.

HSP90 inhibitor PU-H71 increases radiosensitivity of breast cancer cells metastasized to visceral organs and alters the levels of inflammatory mediators.

Heat shock protein 90 (HSP90) inhibitors are considered as new radiosensitizing agents. PU-H71, a novel HSP90 inhibitor, is under evaluation for the treatment of advanced cancer. It is however not known whether PU-H71 alters radiosensitivity of metastatic breast cancer. Hence, we here evaluated mechanisms of possible anti-tumoral and radiosensitizing effects of PU-H71 on breast carcinoma cells metastasized to vital organs such as the liver and brain. The effect of PU-H71 on proliferation of breast carcinoma cells was determined using 4T1 cells and its brain (4TBM), liver (4TLM), and heart (4THM) metastatic subsets as well as non-metastatic 67NR cells. Changes in radiation sensitivity were determined by clonogenic assays. Changes in client proteins and levels of angiogenic and inflammatory mediators from these cancer cell cultures and ex vivo cultures were detected. PU-H71 alone inhibited ERK1/2, p38, and Akt activation and reduced N-cadherin and HER2 which further documented the anti-tumoral effects of PU-H71. The combination of PU-H71 and radiotherapy induced cytotoxic effect than PU-H71 alone, and PU-H71 showed a radiosensitizing effect in vitro. On the other hand, PU-H71 and radiation co-treatment increased p38 phosphorylation which is one of the hallmarks of inflammatory response. Accordingly, IL-6 secretion was increased following PU-H71 and radiotherapy co-treatment ex vivo. Levels of angiogenic and inflammatory factors such as MIP-2, SDF-1, and VEGF were increased under in vitro conditions but not under ex vivo conditions. These results demonstrated for the first time that PU-H71 enhances therapeutic effects of radiotherapy especially in highly metastatic breast carcinoma but a possible increase in inflammatory response should also be considered.

Assessment of clients 'satisfaction with primary health care services in Basra City, South of Iraq 2012

Client satisfaction has been defined as the degree of congruency between a client’s expectation of ideal care and his/her perception of the real care receive. In Iraq, there has been a recent concern at the Ministry of Health (MOH) about improving the quality of Primary Health Care (PHC) services being considered the first health “gate” for the community. This study aimed to assess the level of clients’ satisfaction with PHC services in Basra, Iraq, 2012. A cross-sectional study was performed on 12 randomly selected PHC centers from the total eight PHC districts at Basra Health Directorate, where 1200 clients aged 18 years and above were selected systematically. Data was collected via a direct interview with clients using an Arabic language questionnaire. The satisfaction was rated at a scale of 1-5 points, and the data was analyzed using c. The results of the current study revealed that the overall clients’ satisfaction was 90.8%. The highest score for clients’ satisfaction was for nurses’ staff domain of PHC services (91.9%), and the lowest was for waiting for the domain (74.5%). Old age, females, retired and illiterate clients showed significantly the highest overall satisfaction. Clients reported their main dissatisfaction for the availability of the medicines item (53.4%) and the waiting time to see medical staff item (59%). The present study concluded that overall clients’ satisfaction was relatively high, and socio-demographic characteristics played major roles in deciding the extent of clients’ satisfaction.

Why Do Clinical Practice Guidelines Get Stuck during Implementation and What Can Be Done: A Case Study in Pediatric Rehabilitation

Aims: The purpose of this study was to obtain the perspectives of occupational and physical therapists working in pediatric rehabilitation about the factors that influence implementation of clinical practice guidelines (CPG) using the case of constraint induced movement therapy (CIMT). We aimed to identify factors that hinder implementation of CPGs and strategies for overcoming barriers when widespread implementation is stalled.Methods: Qualitative case study methodology was bounded within the parameters of CIMT implementation in pediatric rehabilitation in one jurisdiction. Twenty-one occupational and physical therapists participated in one of three focus groups. Data were analyzed using an inductive qualitative approach.Results: Participants viewed CPGs as useful, and emphasized the importance of consistency between guidelines and relevance to practice context. Therapists considered the “art and science” in clinical decision-making. Barriers and facilitators to CPG implementation were identified at the client, clinician, intervention location and systemic level. Potential solutions to help “unstick” guideline implementation were consistent with theories of collective knowledge exchange and mindlines.Conclusion: The presence of CPGs does not ensure evidence uptake; understanding of local barriers is required. This case study highlights the value of a collective knowledge exchange approach and attention to the social structures of knowledge development and evidence use.

Quality of Family Planning Services and Associated Factors in Jimma Town Public Hospitals, Southwest Ethiopia.

The quality of care is greatly compromised specially in resource limited settings that influence the uptake and continuation of use of family planning services. However, there is paucity of studies in Jimma Town public hospitals. Thus this study aimed to assess the quality of family planning services and associated factors in Jimma Town public hospitals, Southwest Ethiopia. A facility-based cross-sectional study design using both qualitative and quantitative methods was employed from March 25 to April 25, 2018. A total of 278 female family planning users (15-49 years old) in Jimma Town public hospitals were included in the study.The sample was calculated using single population proportion formula and consecutive sampling methods was used. Descriptive statistics and multiple logistic regressions were used for analysisis. The mean waiting time of the client before getting service and mean consultation duration were23.5 and 12.5 minutes respectively participant who were unable to read and write were 64% less likely to be satisfied than those who were completed primary and secondary or preparatory schooling (AOR=0.363:CI:0.160,0.822), and clients who were waited for < 30 2minutes at waiting area were 2.7 times more likely to be satisfied than those who waited ≥ 30 minutes (AOR=2.769:CI:1.300,5.898). In this study, the satisfaction of clients in family planning service was low. Waiting time and received information on what to do in cases of problems and educational level of clients were significant predictors of client satisfaction.

Target market under MiFID II: the distributor’s perspective

One of the innovations introduced by MiFID II is product governance, including target market assessment as a crucial part of product governance measures. The target market of a financial instrument as an intended group of end clients sharing common characteristics shall generally be determined both by the manufacturer and the distributor of the respective financial instrument. From the related duties, the paper refers to those imposed on the distributor. The paper addresses the following issues. Firstly, what is the target market, including the distributor’s target market, and what are the distinct types of target markets? Secondly, which process and criteria should the distributor apply when assessing the target market? How does the distributor’s target market interact with the manufacturer’s target market and are there any frictions? Thirdly, what are the theoretical and practical issues in case an out-of-scope manufacturer is involved? Is there any specific information the distributor shall assess and if so, where to find it? Finally, which consequences arise from the interaction between target market assessment and the suitability/appropriateness assessment under MiFID II? Namely, could the financial instrument be distributed within the so called negative target market and at the same time be appropriate and/or suitable at the level of an individual client as a representative of the negative target market?

Financial Literacy in Agricultural Products Industry: The Case of Kastamonu

&#x0D; &#x0D; The aim of this study&#x0D; was to reveal the literacy in banking sector of real or legal bank clients who&#x0D; have the right to take commercial and agricultural loans, have bank accounts&#x0D; and are operating in agricultural products industry in Kastamonu city center&#x0D; and districts, and which groups are more financially literate. In the study,&#x0D; the data was acquired by using face-to-face survey method with 400 real and&#x0D; legal persons who are operating in agricultural products industry, and it was&#x0D; determined that the financial literacy level of bank clients increase as the&#x0D; educational level increases. In the survey created in order to measure their&#x0D; knowledge about banking, among the answers given by those concerned, we have&#x0D; tried to determine problems that were considered to be related to each other.&#x0D; Considering the results obtained from the research, suggestions were developed,&#x0D; regarding what must be done in order to improve the banking sector literacy of&#x0D; bank clients in Kastamonu. The survey data indicate that the farmers are not&#x0D; attending to the banking sector at a professional level.

Determinants of the quality of care relationships in long-term care\xa0- a participatory study

BackgroundThe quality of the care relationship between a client and a professional is important in long-term care, as most clients depend on support for a lengthy period. The three largest client groups who receive long-term care in the Netherlands are older adults who are physically or mentally frail, people with mental health problems and people with intellectual disabilities. There is little clarity about how generic and variable the determinants of the quality of care relationships are across these client groups. The aim of this study is to explore and compare the determinants of the quality of care relationships in these three client groups in long-term care.MethodsThis participatory study involving clients as co-researchers was held in three healthcare organizations, each providing long-term care to one client group. The research was conducted by three teams consisting of researchers and co-researchers. We interviewed clients individually and professionals in focus groups. The focus was on care relationships with professionals where there is weekly recurring contact for at least 3 months. Clients and professionals were selected using a convenience sample. The interviews were coded in open, axial and selective coding. The outcomes were compared between the client groups.ResultsThe study sample consisted of 30 clients and 29 professionals. Determinants were categorized into four levels: client, professional, between client and professional, and context. The findings show that the majority of the determinants apply to the care relationships within all three client groups. At the professional level, eleven generic determinants were found. Eight determinants emerged at the client level of which two were found in two client groups only. At the level between a client and a professional, six determinants were found of which one applied to mental healthcare and disability care only. Five determinants were found at the contextual level of which two were specific for two client groups.ConclusionsThe study yielded a variety of determinants that came to the fore in all three client groups in long-term care. This suggests that including a homogenous client group from a single care setting is not necessary when studying the quality of long-term care relationships.

Cooperation of mitochondrial and ER factors in quality control of tail-anchored proteins.

Tail-anchored (TA) proteins insert post-translationally into the endoplasmic reticulum (ER), the outer mitochondrial membrane (OMM) and peroxisomes. Whereas the GET pathway controls ER-targeting, no dedicated factors are known for OMM insertion, posing the question of how accuracy is achieved. The mitochondrial AAA-ATPase Msp1 removes mislocalized TA proteins from the OMM, but it is unclear, how Msp1 clients are targeted for degradation. Here we screened for factors involved in degradation of TA proteins mislocalized to mitochondria. We show that the ER-associated degradation (ERAD) E3 ubiquitin ligase Doa10 controls cytoplasmic level of Msp1 clients. Furthermore, we identified the uncharacterized OMM protein Fmp32 and the ectopically expressed subunit of the ER-mitochondria encounter structure (ERMES) complex Gem1 as native clients for Msp1 and Doa10. We propose that productive localization of TA proteins to the OMM is ensured by complex assembly, while orphan subunits are extracted by Msp1 and eventually degraded by Doa10.

The Contribution of Social Media and Mobile Application to Individual Subjective Well-Being in Counseling Perspective

Various researches in information technology, especially in the era of industrial revolution 4.0 have revealed that there has been a major change in the use of wireless devices in the past decade. The high internet usage is directly proportional to the use of social media which is increasing every year. Social media in principle provides various communities in accordance with the purpose and development goals of the platform. This of course will arouse the arena of new problems at the client's life level, thus becoming a challenge for counselors in the era of industrial revolution 4.0. Counselors in this era are required to have a deeper understanding of the root causes that might arise from the online world. Counselors are also required to have special skills in handling individual welfare conditions related to the impact of activities on social media. This study discusses the general impact of social media on individual subjective well-being conditions. This study involved 174 respondents spread throughout the territory of Indonesia by its demography. The results showed that respondents needed mental health interventions through online channels and not in the form of social media.

Measuring Clients’ Attitudes About Banking Services Quality Using the SERVQUAL Model

Abstract The economic crisis and the emergence of an increasing number of competitors in the banking sector have led to the need for banks to better understand their clients and to work more closely together with them. The basis of survival and profitable business of banks is the achievement of high quality offer that is the asset for developing long-term relationships. The aim of the paper is to determine the effects of the banking services quality dimensions on satisfaction and loyalty of clients using modified SERVQUAL model. The main research question is to examine which dimensions of banking services quality have an effect on the satisfaction and loyalty of clients, what is the nature and the intensity of this impact. For the purpose of measuring clients’ attitudes regarding banking services quality, the survey method, questionnaire technique was applied. The questionnaire was distributed to clients of banks operating in the territory of Kragujevac, Central Serbia, in the period from September to October, 2018. Simple random sample technique for sampling was applied. The analysis was conducted by processing the primary data in statistical software SPSS where several statistical analyses were conducted. Based on multiple regression analysis, it came to the result that the strongest influence on clients’ satisfaction has variable empathy and the weakest variable tangibility, while variable reliability has no influence. On the other hand, clients’ loyalty is most strongly influenced by variable responsiveness while the weakest influence, as well as on satisfaction, has variable tangibility. The paper points to the significance of improving banking services quality in order to achieve higher level of satisfaction and long-term clients’ loyalty, which is particularly important when it comes to dimensions that have weak or no influence on the observed aspects of consumer behaviour.

Introduction of subcutaneous depot medroxyprogesterone acetate through use of community-based distributors in Zambia

Background: The majority of women in Sub-Saharan countries including Zambia use intramuscular Depot Medroxyprogesterone Acetate (DMPA IM) as their preferred method of contraception. However, nearly one-third of the women who start on DMPA IM discontinue within 12 months due to access barriers. Sayana® Press, low-dose, prefilled subcutaneous depot medroxyprogesterone acetate (DMPA-SC), suitable for even lower-level healthcare providers and potential for self-injection administration, has been developed. This pilot aimed to understand the feasibility of DMPA-SC in Zambia through use of community-based distributors (CBDs). Methods: The pilot was implemented from May 2017 to July 2017 in 29 public health facilities in three districts. A total of 161 CBDs received a comprehensive training in DMPA-SC, which included counselling about the method, potential side effects, correct administration and waste management. Post-training mentorship and supervision was conducted. Routine client level data was collected through Ministry of Health management information system. Results: During the pilot, 12,818 clients were provided with modern voluntary FP methods, with 16.4% (2,100) opting for DMPA-SC. The age range of clients opting for DMPA-SC was between 15 and 50 years, with an average of 31 years. Slightly less than half (43%) of DMPA-SC clients were adolescents and young women, with 11% aged 15–19 and 32% aged 20–24. No adverse events were reported during or immediately subsequent to the introduction of DMPA-SC administration by CBDs. Conclusion: The pilot demonstrated that CBDs can safely provide DMPA-SC at the community level with appropriate public sector coordination and oversight.

Effects of Mindfulness Based Cognitive Therapy (MBCT) and Compassion Focused Therapy (CFT) on Symptom Change, Mindfulness, Self-Compassion, and Rumination in Clients With Depression, Anxiety, and Stress.

Objectives: Over the past decade there has been an increasing interest in exploring self-compassion as a related and complementary construct to mindfulness. Increases in self-compassion may predict clinical outcomes after MBCT and cultivation of compassion toward self and others is central to CFT. This pilot study compared the impact of MBCT applying implicit self-compassion instructions and CFT employing explicit self-compassion instructions on symptom change, mindfulness, self-compassion, and rumination.Method: This non-randomized wait-list controlled study (N = 58) with two intervention arms (MBCT N = 20, CFT N = 18, Control N = 20) assessed the outcomes of clients with depression, anxiety, and stress symptoms from before to after the interventions and at one month follow up (MBCT N = 17, CFT N = 13, Control N = 13).Results: Both treatments resulted in significant increases in mindfulness and self-compassion and decreases in rumination, depression, anxiety, and stress. Furthermore, MBCT enhanced mindfulness for people who were initially high in rumination, whereas CFT enhanced mindfulness across the board.Conclusion: The findings suggest that both MBCT and CFT, and hence implicit or explicit self-compassion instructions, produce similar clinical outcomes with CFT enhancing mindfulness regardless of client's rumination level.

Interplay between the Hsp90 Chaperone and the HslVU Protease To Regulate the Level of an Essential Protein in Shewanella oneidensis.

Protein synthesis, folding, and degradation are an accurately regulated process occurring in every organism and called proteostasis. This process is essential to maintain a healthy proteome since proteostasis dysregulation is responsible for devastating cellular issues. Proteostasis is controlled by a complex network of molecular chaperones and proteases. Among them, eukaryotic Hsp90, assisted by many cochaperones and the Hsp70 chaperone system, plays a major role in activating hundreds of client proteins, and Hsp90 inhibition usually leads to proteasomal degradation of these clients. In bacteria, however, the precise function of Hsp90 remains quite unclear, and only a few clients are known. Recently, we have shown that Hsp90 is essential at elevated temperature in the aquatic model bacterium Shewanella oneidensis, and we have identified a client of Hsp90, TilS, involved in tRNA modification. Here we found that two members of the proteostasis network with antagonist activities, the Hsp90 chaperone and the HslVU protease, which is considered the proteasome ancestor, together regulate the level of TilS. In particular, we show that deletion of the genes coding for the HslVU protease suppresses the growth defect of an S. oneidensis strain with hsp90 deleted, by increasing the cellular level of the essential TilS protein. These results open up new avenues for understanding how proteostasis is controlled in bacteria, and new Hsp90 clients are much needed now to confirm the interplay between Hsp90 and proteases.IMPORTANCE Maintaining a healthy proteome is essential in every living cell from bacteria to humans. For example, proteostasis (protein homeostasis) imbalance in humans leads to devastating diseases, including neurodegenerative diseases and cancers. Therefore, proteins need to be assisted from their synthesis to their native folding and ultimately to their degradation. To ensure efficient protein turnover, cells possess an intricate network of molecular chaperones and proteases for protein folding and degradation. However, these networks need to be better defined and understood. Here, using the aquatic bacterium Shewanella oneidensis as a model organism, we demonstrate interplay between two proteins with antagonist activities, the Hsp90 chaperone and the HslVU protease, to finely regulate the level of an essential client of Hsp90. Therefore, this work provides a new bacterial model to better study protein regulation and turnover, and it sheds light on how proteostasis by Hsp90 and proteases could be controlled in bacteria.