Level Laser Therapy Research Articles

Green laser light irradiation enhances differentiation and matrix mineralization of osteogenic cells

Background and objectiveLow level laser therapy (LLLT) in both infrared and visible light is a therapeutic tool ever more proposed in clinical practice in different fields. The effect of near infrared LLLT has been described in a growing number of scientific publications related to bone tissue healing, both in vitro and in vivo. More recently, green visible light using potassium-titanyl-phosphate KTiOPO4 (KTP, 532nm) laser has been proposed in dermatology, urology, oral and maxillofacial surgery but has never been tested on bone tissue. The aim of the present work was to perform a preliminary in vitro study to analyze the effects of KTP laser, on the osteogenic differentiation of bone marrow stromal cells (BMSCs). Materials and methodsUsing a power meter the first step of this study aimed to evaluate the real power emitted by the KTP laser device and the amount of energy absorbed by culture medium and plastic in order to calculate the appropriate irradiation parameters for cultured cells. Primary bone marrow stromal cells prepared from C57BL/6 mice were cultured and induced to differentiate in the osteogenic lineage in the presence or in the absence of KTP LLLT at a fluence of 4J/cm2 three times a week. Specific staining of the cells and the extracellular matrix, microscopic analysis as well as quantitative RT-PCR were used to assess cell proliferation and differentiation. ResultsWe show here that KTP LLLT enhances the osteogenic differentiation of bone marrow stromal cells and the mineralization of their extracellular matrix. ConclusionOur results highlight that this LLLT experimental protocol with green light (KTP, 532nm) at 4J/cm2 has a positive effect on the osteogenic differentiation of murine bone marrow stromal cells. These preliminary results could be used as a basis to further investigate the effect of this KTP laser protocol on bone tissue engineering models in vivo and in vitro.

Effect of low level laser (GaAlAs) therapy on postsurgical healing of full thickness wounds in rabbits

Effect of low level laser (GaAlAs) therapy on postsurgical healing of full thickness wounds in rabbits

Comparison of the long – term effectiveness of physiotherapy programs with low – level laser therapy and pulsed magnetic field in patients with carpal tunnel syndrome

The aim of the study was to compare the long term effects of low - level laser therapy (LLLT) and pulsed magnetic field (PMF) in the rehabilitation of patients with carpal tunnel syndrome (CTS). The study included 38 patients with idiopathic CTS, confirmed by electroneurographic (ENG) examination. All patients were randomly assigned to 2 groups: group L (18 patients) treated with LLLT and group M (20 patients) with PMF therapy. Clinical assessment, including day and night pain, the presence of paresthesia, functional tests (Phalen, Tinel, armband tests) and pain severity according to the Visual Analogue Scale (VAS) was conducted before treatment, after the first series of 10 sessions, after a two-week break, after the second series of 10 sessions and six months after the last series. After LLLT a significant reduction of day and night pain was observed at each stage of treatment and 6 months after the last series (p<0.05). However, in group M, a significant reduction of both day and night pain was demonstrated only after the second series (p<0.05). A reduction of the incidence of Phalen's symptoms were noticed in both groups, however, only in group L the improvement was significant (p<0.05). In groups L and M a significant reduction of pain intensity was observed at every stage of treatment (p<0.05). Although after LLL as well as PMF therapy clinical improvement was observed, the most significant differences were registered after the second series and persisted for up to 6 months in both groups.

Effects of Low Level Laser (He-Ne) Therapy on the Allodynia after Sciatic Compressed Nerve Injury in Rats

Effects of Low Level Laser (He-Ne) Therapy on the Allodynia after Sciatic Compressed Nerve Injury in Rats

Low Level Laser Therapy Is Not Low

Photomedicine and Laser SurgeryVol. 23, No. 6 EditorialLow Level Laser Therapy Is Not LowChukuka S. EnwemekaChukuka S. EnwemekaSearch for more papers by this authorPublished Online:15 Dec 2005https://doi.org/10.1089/pho.2005.23.529AboutSectionsPDF/EPUB ToolsPermissionsDownload CitationsTrack CitationsAdd to favorites Back To Publication ShareShare onFacebookTwitterLinked InRedditEmail "Low Level Laser Therapy Is Not Low." , 23(6), pp. 529–530FiguresReferencesRelatedDetailsCited byThe New Paradigm Lars Hode8 December 2021 | Photobiomodulation, Photomedicine, and Laser Surgery, Vol. 39, No. 12Patient-reported outcomes of laser-assisted pain control following non-surgical and surgical periodontal therapy: A systematic review and meta-analysis17 September 2020 | PLOS ONE, Vol. 15, No. 9Light-emitting diode photobiomodulation therapy for non-specific low back pain in working nurses7 August 2020 | Medicine, Vol. 99, No. 32Photobiomodulation in Pediatric Dentistry: A Current State-of-the-Art Carlo Fornaini, Praveen Arany, Jean-Paul Rocca, and Elisabetta Merigo20 December 2019 | Photobiomodulation, Photomedicine, and Laser Surgery, Vol. 37, No. 12Photobiomodulation Therapy in Oral Medicine: A Guide for the Practitioner with Focus on New Possible Protocols Elisabetta Merigo, Jean-Paul Rocca, Antonio L.B. Pinheiro, and Carlo Fornaini12 November 2019 | Photobiomodulation, Photomedicine, and Laser Surgery, Vol. 37, No. 11Only lasers can be used for low level laser therapy13 November 2017 | BioMedicine, Vol. 7, No. 4Biophotonics and the Life Sciences5 November 2015 | Photomedicine and Laser Surgery, Vol. 33, No. 11Low-Level Laser Therapy in odontostomatologia: istruzioni per l’usoDental Cadmos, Vol. 83, No. 7Short-term therapeutic effects of 890-nanometer light therapy for chronic low back pain: a double-blind randomized placebo-controlled study3 July 2013 | Lasers in Medical Science, Vol. 29, No. 2Low-level laser reduces the production of TNF-α, IFN-γ, and IL-10 induced by OVA22 January 2013 | Lasers in Medical Science, Vol. 28, No. 6Low Level Laser Therapy (LLLT) and World Association for Laser Therapy (WALT) Dosage Recommendations2 February 2012 | Photomedicine and Laser Surgery, Vol. 30, No. 2Wavelength effect in temporomandibular joint pain: a clinical experience30 June 2009 | Lasers in Medical Science, Vol. 25, No. 2Laser Phototherapy in Dentistry1 July 2009 | Photomedicine and Laser Surgery, Vol. 27, No. 4 Volume 23Issue 6Dec 2005 InformationCopyright 2005, Mary Ann Liebert, Inc.To cite this article:Chukuka S. Enwemeka.Low Level Laser Therapy Is Not Low.Photomedicine and Laser Surgery.Dec 2005.529-530.http://doi.org/10.1089/pho.2005.23.529Published in Volume: 23 Issue 6: December 15, 2005PDF download