Summary In conclusion, our evidence shows that acute poliomyelitis can be favorably influenced by this treatment. This statement is based upon the following experience: First, 10 cases of respiratory paralysis have been treated, all of which recovered. Improvement in respiratory function is both objective and subjective, and occurs during the actual treatment period. One of the respiratory cases showed complete paralysis of both diaphragms and intercostals before treatment. In the past all cases showing this much paralysis have been fatal. The behavior of this group I believe shows that the use of the respirator will become unnecessary in the future management of this type of paralysis. Second, 6 cases of paralysis of deglutition have all recovered promptly. All cases so treated have been able to drink fluids following the first treatment, an event which cannot be explained on a basis of coincidence, as paralysis of the throat does not thus improve in untreated cases. Third, both of the above groups carry a mortality rate of around 50 per cent, and while this group is scarcely large enough for statistical evaluation, it included 16 cases with recovery in each instance. The preparalytic group included in this report were all cases in which the disease was sufficiently severe that paralysis might be a reasonable expectancy. I have 7 other cases in my records of preparalytic cases, not included here since they were apparently milder in their course, and their recovery would not add any significance to this group. Fourth, I am confident that this treatment will not in every instance prevent the development of paralysis. This is particularly true in the ascending (Landry's) type. In these cases the progress of the paralytic process is rapid and the case fulminating in nature. Resistance of the patient, for some reason not known, is definitely less than in the usual type. However, the respiratory paralysis from which the Landry's type dies, does yield to the treatment and it is therefore possible to save these patients' lives. More vigorous treatment is indicated in this group than I have used in the past. Fifth, weakness of the muscles of the extremities, without actual paralysis, has promptly improved and I have often seen reflexes return following treatment, which have not responded to stimuli before treatment was given. Sixth, actual paralysis of the muscles of the extremities does not improve. However, treatment of this group is advised if the case is “active,” with the hope of preventing further loss of function. Seventh, finally, we have been able to prevent paralysis and death in Rhesus monkeys which have been infected with many times the lethal dose of virus; all of our control animals having died after complete skeletal paralysis.