Lens Implantation Research Articles

Effectiveness of toric intraocular lens implantation for correcting irregular corneal astigmatism in cataract eyes

A retrospective cohort study was conducted to observe the correction effect of Toric intraocular lens (IOL) implantation in cataract eyes with specific types of irregular corneal astigmatism. Thirty-four eyes with either the "asymmetric bow-tie" pattern (Type I) or the "angled bow-tie" pattern (Type II) were included. Corneal topography was assessed using Pentacam HR, and changes in preoperative corneal astigmatism, visual acuity, manifest refraction, and objective visual quality were measured and compared. The average uncorrected distance visual acuity improved significantly from 0.86 ± 0.40 logMAR to 0.22 ± 0.15 logMAR (P < 0.001). Preoperative corneal astigmatism of 2.05 ± 0.90 D was corrected to a postoperative residual astigmatism of 0.78 ± 0.57 D (P < 0.001), with 32% of eyes within 0.50 D. The residual astigmatism prediction errors in Type I and Type II cases were (0.97 ± 0.68 D) and (0.66 ± 0.37 D), respectively (P = 0.100). The mean spherical equivalent prediction error in Type II cases (0.07 ± 0.36 D) was significantly smaller than that in Type I cases (− 0.29 ± 0.52 D) (P = 0.030). This study concludes that Toric IOL implantation effectively corrects specific types of irregular corneal astigmatism in cataract surgery. Eyes with the "angled bow-tie" pattern show higher accuracy in refractive predictions compared to eyes with the "asymmetric bow-tie" pattern.

Accuracy of toric intraocular lens power calculation depending on different keratometry values using a novel network based software platform.

To compare different corneal keratometry readings (swept-source-OCT-assisted biometry and Scheimpflug imaging) with a novel software platform for calculation of toric intraocular lenses. Department of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany. Retrospective, non-randomized, clinical trial. Twenty-three eyes undergoing toric intraocular lens implantation were included. Inclusion criteria were preoperative regular corneal astigmatism of at least 1.00 D, no previous refractive surgery, no ocular surface diseases and no maculopathies. Lens exchange was performed with CALLISTO eye (Zeiss). For each patient, the expected postoperative residual refraction was calculated depending on three different corneal parameters of two different devices: standard K-front (K) and total keratometry (TK) obtained by a swept-source-OCT-assisted biometry system (IOL Master 700, Zeiss) as well as total corneal refractive power (TCRP) obtained by a Scheimpflug device (Pentacam AXL, Oculus). Barrett's formula for toric intraocular lenses was used for all calculations within a novel software platform (EQ workplace, Zeiss FORUM®). Results were statistically compared with postoperative refraction calculated according to the Harris dioptric power matrix. The standard K values (mean PE 0.02 D ± 0.45 D) and TK values (mean PE 0.09 D ± 0.43 D) of the IOL Master 700 reached similar results (p = 0.96). 78% of eyes in both K and TK groups achieved SE within ±0.5 D of attempted correction and all eyes (100%) were within ±1.0 D of attempted correction in both groups. By contrast, the prediction error in the IOL calculation using the TCRP of the Scheimpflug device was significantly greater (mean PE -0.56 D ± 0.49 D; p = 0.00 vs. standard K and p = 0.00 vs. TK) with adjusted refractive indices. Thirty-nine and Ninety-one percentage of eyes in the TCRP group achieved SE within ±0.5 D (p = 0.008 K vs. TCRP and p = 0.005 TK vs. TCRP) and ± 1.0 D (p = 0.14 vs. TCRP) of attempted correction, respectively. All three corneal parameters (standard K, TK, TCRP) performed well in calculating toric IOLs. The most accurate refractive outcomes in toric IOL implantation were achieved by IOL calculations based on swept-source-OCT-assisted biometry. The SS-OCT-based K-front and TK values achieve comparable results in the calculation of toric IOLs.

Influencing factors of effective lens position in patients with Marfan syndrome and ectopia lentis

AimsThe aim of this study was to analyse the effective lens position (ELP) in patients with Marfan syndrome (MFS) and ectopia lentis (EL).MethodsPatients with MFS undergoing lens removal and primary...

Bilateral anterior capsular phimosis in an 85-year-old female patient after stand-alone cataract extraction with intraocular lens implantation

Introduction: Anterior capsular phimosis is a rare complication after cataract extraction with intraocular lens implantation. Patient and clinical findings: An 85-year-old female underwent manual phacoemulsification with toric intraocular lens implantation in the right eye (OD) without any post-operative complications. Approximately 1.5 weeks later, she had the same procedure in the left eye (OS) with similar success. At post-operative week 6 OD and week 4 OS, distance visual acuity without correction was 20/400 OD and hand motion (HM) OS. Anterior segment examination revealed intraocular lens implants with a significant fibrotic anterior capsule in both eyes. Posterior segment examination showed pigmentary macular changes in both eyes that were unchanged from the pre-operative evaluation. Diagnosis, intervention, and outcomes: The patient was diagnosed with bilateral anterior capsular phimosis. She underwent Nd:YAG laser capsulotomy in the left eye, then in the right eye 1 week later. At Nd: YAG laser capsulotomy post-operative day 4 OD and week 2 OS, distance visual acuity without correction was 20/40 OD, OS with best corrected visual acuity 20/30 OD, OS. Conclusions: Anterior capsular phimosis can occur in both eyes sooner than 4 weeks after cataract extraction with intraocular lens implantation in a patient with no risk factors.

Evaluation of changes of anterior segment parameters in patients with pseudoexfoliation syndrome after cataract surgery using anterior segment optical coherence tomography

The aim of the study was to compare the anterior segment parameters after cataract surgery in pseudoexfoliation syndrome (PEX) and control eyes. We conducted a prospective comparative study of 36 eyes (PEX group), 16 eyes (PEXG group) and 46 eyes (control group) of 98 patients after phacoemulsification with intraocular lens implantation. Before surgery, 1 week, 1 month and 3 months postoperatively, anterior chamber parameters were evaluated by swept source anterior segment optical coherence tomography (AS-OCT). Anterior chamber depth (ACD), angle opening distance (AOD500/750), trabecular-iris space area (TISA500/750), trabecular-iris angle (TIA500/750) and lens vault (LV) were assessed at each study visit. Preoperatively, ACD, AOD500/750 and TISA500/750 were significantly smaller, while LV was significantly greater in PEX and PEXG eyes than in controls. 3 months postoperatively all irido-corneal parameters and ACD were significantly greater in all study groups without intergroup differences. ACD and LV significantly increased in PEX group between 1 and 3 months after surgery while being stable in control group. Relative increases in ACD, AOD500, TISA750, TIA500/750 were significantly higher in PEX and PEXG groups than in controls. Our study finds that ACD and iridocorneal parameters in AS-OCT demonstrated significantly greater relative increases 3 months after phacoemulsification in PEX and PEXG groups than in control eyes. Significantly greater deepening of anterior chamber and opening of the irido-corneal angle may be a reason for different refractive outcomes and IOP control in patients with PEX and PEXG after routine cataract surgery.

Clinical efficacy of femtosecond laser-assisted phacoemulsification in diabetic cataract patients.

Diabetic patients with cataracts encounter specific difficulties during cataract surgery due to alterations in microcirculation, blood supply, metabolism, and the microenvironment. Traditional phacoemulsification may not fully tackle these issues, especially in instances with substantial preoperative astigmatism. The utilization of femtosecond laser-assisted phacoemulsification, in conjunction with Toric intraocular lens (IOL) implantation, offers a potentially more efficient strategy. This research seeks to evaluate the efficacy and possible complications of this approach in diabetic cataract patients. To investigate the clinical efficacy and complications of femtosecond laser-assisted phacoemulsification combined with Toric IOL implantation in diabetic cataract patients, comparing it with traditional phacoemulsification methods. This retrospective study enrolled 120 patients with diabetes cataract from May 2019 to May 2021. The patients were divided into two groups: the control group underwent traditional phacoemulsification and Toric IOL implantation, while the treatment group received Len Sx femtosecond laser-assisted treatment. Outcome measures included naked eye vision, astigmatism, high-level ocular phase difference detection, clinical efficacy, and complication. There were no significant preoperative differences in astigmatism or naked eyesight between the two groups. However, postoperative improvements were observed in both groups, with the treatment group showing greater enhancements in naked eye vision and astigmatism six months after the procedure. High-level corneal phase difference tests also indicated significant differences in favor of the treatment group. This study suggests that femtosecond laser-assisted phacoemulsification combined with Toric IOL implantation appears to be more effective in enhancing postoperative vision in diabetic cataract patients compared to traditional methods offering valuable insights for clinical practice.

The Effect of Phacoemulsification on the Intraocular Pressure of Patients With Open Angle Glaucoma: A Systematic Review and Meta-Analysis.

There is evidence that cataract surgery can reduce intraocular pressure in patients with primary open angle, normal tension, or exfoliative glaucoma. The complete effect of phacoemulsification is masked by topical intraocular pressure-lowering medications. To assess the impact of phacoemulsification and intraocular lens implantation on intraocular pressure (IOP) level in individuals with primary open angle glaucoma (POAG), exfoliative glaucoma (XFG), exfoliation syndrome (XFS), normal tension glaucoma (NTG), ocular hypertension (OH), or healthy controls 12 months after the surgery. In July 2023, a comprehensive literature review was conducted across six databases. The analysis focused on the phacoemulsification arms of randomized controlled trials (RCTs). The primary outcome of interest was the mean IOP change observed 12 months after phacoemulsification. This meta-analysis included 9 arms from 9 RCTs, comprising a total of 502 participants. Overall, the average IOP was reduced by 3.77mm Hg (95% CI: -5.55 to -1.99, I2 =67.9%) 12 months after surgery. The subgroup analysis, focused on whether a washout period was used before measuring IOP, revealed that studies with a washout period exhibited a more pronounced IOP reduction of 5.25mm Hg (95% CI: -7.35 to -3.15, I2 =0%), while studies without a washout period exhibited a reduction of 3.13mm Hg (95% CI: -5.46 to -0.81, I2 =75.8%). The sensitivity analysis for the latter group, excluding an outlier study, showed a reduction of 1.81mm Hg (95% CI: -2.95 to -0.67, I2 =0%). The findings of this systematic review and meta-analysis indicate that cataract surgery meaningfully lowers IOP in POAG, XFG/XFS, or OH 12 months after surgery. However, the use of topical medications masks the precise impact of phacoemulsification upon postoperative IOP. Further research using appropriate washout periods is warranted.

Visual Outcomes According to Age After Bilateral Implantation of Trifocal Intraocular Lenses.

To investigate the effect of age on visual outcomes after the bilateral implantation of trifocal intraocular lenses (IOLs). A total of 290 patients (580 eyes) who underwent bilateral implantation of a trifocal IOL were enrolled in this retrospective case-control study. Patients were divided into five age groups: 45 to 49, 50 to 54, 55 to 59, 60 to 64, and 65 years and older. Postoperative monocular uncorrected and corrected distance visual acuity (UDVA and CDVA, respectively), uncorrected near visual acuity (UNVA), binocular distance-corrected defocus curve, spectacle dependence for near and distance vision, and patient satisfaction scores were compared among the five groups. The 45 to 49 years group had significantly better mean UDVA (0.02 ± 0.05 logMAR) and UNVA (0.02 ± 0.04 logMAR) than the 65 years and older group (0.06 ± 0.09 and 0.09 ± 0.09 logMAR; P = .029 and P < .001; respectively). However, no significant differences were observed in the mean CDVA among the groups. Binocular visual performance of the 45 to 49 years group was better than that of the 65 years and older age group at defocuses of +1.00, +0.50, -1.00, and -3.00 D. No significant differences were observed in spectacle dependence for near and distance vision or in patient satisfaction scores among the five groups. Bilateral implantation of trifocal IOLs can provide excellent near and distance vision in both young and older patients. However, UDVA and UNVA revealed considerably worse results in the older group, although no significant difference was observed in CDVA and postoperative refractive errors by age. [J Refract Surg. 2024;40(4):e270-e277.].

Phacoemulsification with implantation of a trifocal intraocular lens in eyes with asteroid hyalosis and synchysis scintillans

To compare the visual outcomes in both eyes of patients who undergo phacoemulsification and trifocal intraocular lens (IOL) implantation and have asteroid hyalosis (AH) or synchysis scintillans (SS) in only one eye. A retrospective comparative case series was performed. We evaluated uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA), uncorrected intermediate visual acuity (UIVA), uncorrected near visual acuity (UNVA), predictability, safety, efficacy, and satisfaction after implantation of the same model of trifocal IOL in both eyes (PhysIOL FineVision Pod-F and Micro-F and Rayner RayOne Trifocal). A total of 164 eyes of 82 patients (41 females, 50%) met the inclusion criteria. There were no statistically significant differences in sphere, cylinder, spherical equivalent, UDVA, UIVA, or UNVA between the groups. Postoperative CDVA was slightly better in the control group (logMAR 0.03) than in the AH/SS group (logMAR 0.04) (P: 0.014). There were no statistically significant differences in predictability, safety index, or efficacy index between the groups. Overall subjective satisfaction was good (98.2%). Visual outcomes and satisfaction are good after implantation of trifocal IOLs in eyes with AH or SS. Therefore, trifocal IOLs should not be ruled out in these patients when no other vitreoretinal disorder is present.

A comparative study on intraoperative complication with posterior vitrectorhexis versus forcepsorhexis before implantation of intraocular lens in children.

Objective: To compare intraoperative complications in manual posterior capsulorhexis (forcepsorhexis) and posterior vitrectorhexis, before implantation of the IOL in patients of paediatric cataract surgery. Study Design: Observational study. Setting: Department of Ophthalmology, Shaheed Mohtarma Banazir Bhutto Medical University Larkana. Period: July 2021 to June 2022. Methods: Our study included patients within the age range of 1-12 years who were diagnosed with congenital cataract and did not exhibit any other abnormalities in the anterior or posterior segments. A comprehensive ophthalmic and systemic examination was conducted, and the patients were categorized into two groups: Group A for Forceps Capsulorhexis and Group B for Posterior Vitrectorhexis. Results: There were a total of 154 cases of paediatric cataracts that underwent surgical procedures known as Posterior capsulorhexis (forcepsorhexis) and posterior vitrectorhexis. Both groups had participants with ages ranging from 1 year to 12 years, with a minimum age of 1 year. The mean age for the Forceps Capsulorhexis group was 6.1+1.8 years, while the mean age for the Posterior Vitrectorhexis group was 6.9+1.3 years. The outcomes during surgery showed that in the Forceps Capsulorhexis group, 60 patients (77.92%) had organization of the capsular bag, while in the Posterior Vitrectorhexis group, 49 patients (63.63%) had organization of the capsular bag. Additionally, 55 patients (71.42%) in the Forceps Capsulorhexis group experienced vitreous thrust into the anterior chamber, compared to 66 patients (85.71%) in the Posterior Vitrectorhexis group. Conclusion: The safety and effectiveness of Forceps capsulorhexis as a treatment for paediatric cataract surpasses that of the posterior vitrectorhexis procedure, as concluded by our study.

Impact of posterior vitreous detachment on visual acuity after the implantation of a diffractive multifocal intraocular lens

Purpose: To investigate the effect of posterior vitreous detachment (PVD) on visual acuity (VA) after implantation of a diffractive multifocal intraocular lens (mIOL). Setting: Eye Clinic, Okayama, Japan. Design: Retrospective case series. Methods: This study evaluated 475 eyes of 475 patients who underwent cataract surgery with a TECNIS Multifocal ZLB00 lens implant between November 2017 and October 2019. Patient eyes were classified into the complete PVD group (PVD group) or the control group with no PVD/partial PVD (non-PVD group) and divided into 3 age categories: 65 to 69, 70 to 74, and 75 to 79 years. The postoperative VA of the PVD and non-PVD groups was compared between and within groups by age. Results: Distance-corrected near VA (DCNVA) was significantly worse in the PVD group than in the non-PVD group in all age categories (P ≤ .029). In the PVD group, both corrected distance VA (CDVA) and DCNVA were significantly worse in the 75 to 79 years age group than in the 65 to 69 and 70 to 74 years age groups (P ≤ .034). CDVA and DCNVA in the non-PVD group did not differ significantly between age categories. Conclusions: The results of this study suggest that complete PVD worsens near VA in eyes with a diffractive mIOL. Furthermore, eyes with complete PVD may show an age-related decline in both CDVA and DCNVA. In particular, eyes ≥75 years of age with complete PVD have a poor visual prognosis and should be given careful consideration when deciding whether to implant a diffractive mIOL.

Implantation of Hydrophobic Acrylic Toric Intraocular Lens with High-Water Contents Using Swept-Source Optical Coherence Tomography Biometer Integrated with a Surgical Guiding System.

To evaluate postoperative outcomes after implantation of toric intraocular lenses (IOLs) made of high-water-content hydrophobic acrylic material in Japanese patients using a swept-source optical coherence tomography (SS-OCT) biometer integrated with a surgical guiding system. In this prospective observational study, toric IOL models CNW0T3 to CNW0T9 (Alcon) were implanted in 33 eyes of 33 patients and followed-up for one month. Powers and toric models were determined using an SS-OCT biometer ARGOS® Ver 1.5 (Alcon), and the IOLs were aligned using surgical guidance. Differences between planned and actual axis positions at the end of the surgery (misalignment) and rotations from the end of surgery to one month postoperatively were measured. Additionally, postoperative uncorrected visual acuity, refraction, and residual astigmatism were evaluated. Mean and median misalignments were 2.3° (standard deviation [SD]: 1.6, 95% confidence interval [CI]: 1.7-2.9) and 2°, and those of postoperative rotation were 2.4° (SD: 2.6, 95% CI: 1.5-3.4) and 2°, respectively. Mean postoperative refraction was 0.06 D (SD: 0.62). Prediction errors within ±0.5 and ±1.0 D were 69.7% and 93.9%, respectively. Mean residual astigmatisms were 0.19 D (SD: 0.41), and mean uncorrected visual acuity was 0.00 logMAR (SD: 0.11), and 64% of the eyes scored 20/20 or better. Implantation of high-water-content hydrophobic acrylic toric IOLs using SS-OCT biometry integrated with a surgical guiding system effectively corrected corneal astigmatism with accurate IOL alignment in Japanese patients.

Management of traumatic dislocated polymethyl methacrylate intraocular lens following globe rupture in a monocular patient: A case report

A 72-year-old monocular male with no light perception in the left eye and a history of cataract extraction with polymethyl methacrylate (PMMA) intraocular lens (IOL) implantation and retinal detachment repair with scleral buckling in the right eye presented after a forward fall and hitting his face with a large iris defect, irregular pupil, superior zone 2 globe rupture, dense vitreous hemorrhage, and a 1-piece PMMA IOL dislocated in the posterior chamber in the right eye. His visual acuity on presentation was hand motion with directionality, with no improvement on pinhole. PMMA IOLs are difficult to cut and require larger incisions for removal, which was difficult in our patient with open-globe rupture. His large iris defect and minimal capsular support ruled out other options such as the implantation of a new IOL. IOL repositioning with scleral suturing resulted in the successful salvation of his IOL and visual acuity.

Patient-Reported Outcome Measures in Cataract Surgery

Abstract Purpose: To assess the patient-reported outcome measures and health-related quality of life in cataract patients after their cataract surgery. Method: A prospective observational pilot study was conducted on 197 patients with cataract who underwent phacoemulsification cataract surgery in an urban-based eye care hospital. Result: Out of 197 patients, 110 patients fulfilled the inclusion criteria of the study. In our study, we chose Catquest-9SF as our parent questionnaire and made a few modifications in it based on the livelihood of our patients. The patient satisfaction percentage with reference to improvement in vision after cataract surgery with intraocular lens (IOL) implantation in our study was 87%. A total of 96% of the patients who had multifocal/trifocal IOL implantation were completely satisfied with the cataract surgery. Conclusion: Due to improvement in life expectancy of elderly patients and increased usage of gadgets by them, spectacle independence and functional improvement have become their requirements. With standardised techniques, expertise and experience with the right use of advanced equipment and appropriate IOLs, we were able to get excellent results and complete patient satisfaction by knowing their lifestyle and requirement. Patient-reported outcome measures helped us in improving the vision and health-related quality of life after cataract surgery.

Functional Approach to IOL Selection in Eyes With Combined Cataract and Keratoconus With an Option for Refractive Lens Exchange.

To evaluate spherical intraocular lens (IOL) implantation for cataracts in keratoconic eyes followed by optional refractive toric lens exchange to improve uncorrected visual acuity. This retrospective study evaluated cataract surgery outcomes in keratoconic eyes. Eyes treated with a spherical IOL targeted for -2.00 diopters (D) either achieved acceptable manifest refraction and desired exchange with a toric IOL (Group 1); achieved satisfactory manifest refraction and chose to use spectacles or contact lenses (Group 2); or did not achieve acceptable refraction and used contact lenses (Group 3). Group 4 had single-stage toric IOL implantation with plano target. Corrected and uncorrected distance visual acuity (CDVA and UDVA) and keratometry were analyzed. Groups 1 to 4 had 18, 23, 18, and 26 eyes, respectively. A staged toric exchange resulted in significantly better (P = .02) UDVA (mean: 0.15 logMAR; 20/25 Snellen) than initial toric IOL implantation (0.24 logMAR; 20/30 Snellen). All toric IOL exchange eyes achieved 20/30 or better CDVA and 94% had 20/40 or better UDVA. Mean manifest cylinder significantly decreased from 3.39 D before lens exchange to 1.10 D postoperatively. Initial implantation of a spherical IOL in keratoconic eyes allows basing toric calculations on the manifest refraction, which may be more reliable than keratometry measurements in keratoconic eyes. UDVA after staged toric IOL exchange was significantly better than after initial toric IOL implantation. Importantly, by staging use of toric lenses, the authors avoided cases where patients required a rigid contact lens after a toric IOL was implanted. [J Refract Surg. 2024;40(4):e207-e217.].

Erratum to: Clinical and laboratory studies on the effects of capsular tension ring on surgical outcomes of trifocal intraocular lens implantation.

Erratum to: Clinical and laboratory studies on the effects of capsular tension ring on surgical outcomes of trifocal intraocular lens implantation.

Implantable Collamer Lens Procedure Planning: A Review of Global Approaches.

More than 2 million implantable collamer lenses (ICLs) have been implanted worldwide. With a central port to improve aqueous flow through the ICL, the latest iteration of this phakic intraocular lens (pIOL) has been shown to have stable outcomes with very low rates of adverse events. However, correct planning and ICL size selection continue to be important to achieve an optimal vault. Shallow or excessive vaults are not complications in and of themselves but may increase the risk of complications. Historically, surgeons have relied on measurements of anterior chamber depth (ACD) and manual, caliper-measured white-to-white (WTW) distance to select the ICL size. New diagnostic and imaging technologies such as optical coherence tomography (OCT) and ultrasound biomicroscopy (UBM) provide additional opportunities for visualization and measurement of the intraocular dimensions involved in phakic intraocular lens implantation, including sulcus-to-sulcus (STS) and angle-to-angle (ATA) diameters. This paper reviews various approaches to ICL planning and sizing that have been published in the peer-reviewed literature, all of which produce acceptable results for predicting vault and size selection. Surgeons may also want to identify a methodology for patient evaluation and ICL size selection that best aligns with their personal preferences, diagnostic technology, and familiarity with analytical optimization tools.

Endothelial cell loss post-implantable collamer lens V4c: meta-analysis.

Endothelial cell density (ECD) loss is a noted effect of implantable collamer lens (ICL) V4c surgery. Current literature provides a wide range of values for ECD loss postsurgery, which may not be helpful in advising patients and clinicians. A meta-analysis exploring ECD loss in ICL V4c for myopia correction was undertaken. 18 studies were included in this meta-analysis with 2 subgroup analyses to account for the variability in follow-up lengths. The average ECD loss 3 months, 12 months, and 21.25 (mean) months postsurgery were 1.32% ± 1.28% ( P < .001, 95% CI, -75.158 to -1.19), 1.75% ± 2.17% ( P < .001, 95% CI, -134.09 to 14.52), and 3.84% ± 1.78% ( P < .001, 95% CI, -156.04 to -54.26), respectively. ECD loss is most pronounced 3 months postsurgery, suggesting that acute surgical trauma was the primary contributor rather than long-term lens implantation. Overall, ICL V4c is for myopia correction exhibits similar ECD loss as seen in other ICL models, thereby affirming its safety.

Endogenous Serratia marcescens endophthalmitis in an 11-year-old immunocompetent boy – A case report and review of literature

The authors report a rare case of successfully treated endogenous endophthalmitis in an 11-year-old healthy child who presented with a sudden decrease in vision associated with redness and pain in his left eye. There was no history of ocular trauma or recent hospitalization. The patient had acute severe panuveal inflammation with white hypopyon. Emergency pars plana vitrectomy with lensectomy was done and intravitreal antibiotics were administered. Vitreous biopsy grew Serratia marcescens on blood agar. The patient was treated with multiple intravenous, oral, and topical antibiotics based on VITEK 2 antibiotic susceptibility testing. Secondary intraocular lens implantation resulted in a best corrected visual acuity of 20/60.

A case of Phialemoniopsis curvata keratitis and literature review

We reported the case of a keratomycosis caused by an extremely rare filamentous fungus. A patient with a history of phacoemulsification and intraocular lens implantation surgery followed by bullous keratopathy and was wearing a bandage contact lens presented with signs of keratitis. Microbiological examinations revealed a filamentous fungus identified as Phialemoniopsis curvata. Penetrating keratoplasty was performed due to spontaneous corneal perforation during the treatment. P. curvata is an extremely rare agent of fungal keratitis. Although the course of infection is serious, recovery without sequela may be possible with early diagnosis and appropriate treatment.