Mullets form a major component of pelagic fish landings in tropical areas. M. cephalus Linnaeus, 1758 were collected from Kilifi creek between October 2002 and September 2004 using gillnets and a cast net. The sampling sites were Nkoma, Mazioni, Kidundu and Kombeni sites in the southern arm while the northern arm had Sea Horse, Fumbini, Konjora and Rare sites chosen based on observed physical characteristics. The total length (mm), total weight (g) was recorded and the abdomen dissected for gonad identification. From 765 specimens obtained, length-weight relationship (Regression and test of isometry), relative condition factor (Kn), age and growth (Von Bertalanffy Growth Equation VBGE) were performed. In 537 males, length ranged between 57mm and 480mm, the weight between 3g and 1169g. The regression line fitted for length on weight was Log10 W = 1.7457 + 2.8658 Log10 L and the test of isometry (b=2.8658) was significantly different from 3 (t^ = 21.2138; P < 0.05). The length ranged between 61mm and 507mm, weight between 3.8g and 1385g in 228 females. The regression line fitted for length on weight being Log10 W = 1.7973 + 2.8955 Log10 L and the test of isometry (b=2.8955) was significantly different from 3 (t^ = 13.5536; P < 0.05). Low monthly variations in the relative condition factors between the sexes as well as during the different seasons was observed, however, the males had higher relative condition factors than females. Asymptotic length (VBGE) was calculated for M. cephalus at each site with largest fishes caught at Sea Horse, Nkoma, Fumbini and Mazioni while the smallest fishes were from Kombeni and Kidundu. In females, the asymptotic length L∞ (51.48 cm) was higher than in males (48.3 cm) and no notable difference was observed in K (growth coefficient) between females (0.83) and males (0.79) respectively. Kilifi creek needs conservation as source of juveniles for stocking in ponds for future culture