Biological characteristics of Yellowstrip Scad - Selaroides leptolepis (Cuvier, 1833) were analyzed by using the fisheries biology data collected in landing sites from 2014 to 2015 in the Southwest Sea of Vietnam. Results indicated that the main lengh of Yellowstrip scad in the Southwest sea was 11.3 cm, in the range of 4.5cm to 15.4 cm. The length-weight relationship equations was W=0,000008L3,154 (male), W= 0,000009L3,114 (female), W=0,00002L2,965 (juvenile). Growth parameters (L∞ and K) of the von Bertalanffy equation were 16.3 cm and 1.2/year, respectively. The length at first maturity of fish (Lm50) was 9.8 cm. Male/Female rate of fish was 1.1. The Yellowstrip scad breeds throughout the year but the spawning peaks are observed from Febuary to April. The total mortality Z=4.24/year, the instantaneous natural mortality due to predation, aging and other environmental causes with M= 2.39/year, the instantaneous fishing mortality caused by fishing F=1.85/year and exploitation rate E= 0.44/year.