Objective: This study aims to analyze the diagnostic value of echocardiography in patients with chronic heartfailure. Methods: 30 patients with chronic heart failure admitted to our hospital during January 2021 to January 2023 were selected as the observation group, and 30 healthy people who received physical examination in our hospital during the same period were selected as the reference group. Both groups received echocardiography, and the results of the ultrasound examination were compared, and the subjects in the observation group were grouped according to the New York Heart Association (NYHA) cardiac function grading standard. The results of echocardiography in patients with chronic heart failure of different cardiac function grades were compared. Results: The left ventricular ejection fraction (LVEF) and ratio of maximum blood flow in the early diastole (E) to movement speed (A) (E/A) in the observation group were lower than those in the reference group, while the left ventricular posterior wall thickness (LVPWd), left ventricular end-diastolic diameter (LVEDD), left ventricular end-systolic diameter (LVESD), left atrial diameter (LAD), and interventricular septal thickness (IVS) were higher than those of the reference group (P < 0.05). With the continuous increase of cardiac function grades, the levels of LVEF and E/A in patients with chronic heart failure continued to decrease, while the levels of LVPWd, LVEDD, LVESD, LAD, and IVS continued to increase, and there were significant differences among the groups (P < 0.05).Conclusion: The application of echocardiography in the clinical diagnosis of chronic heart failure can accurately evaluate the changes of cardiac shape and cardiac function, and provide a reliable basis for clinical diagnosis with a high application value.