Left Hand Grip Strength Research Articles

Do the physical elements improving archery performance?

Archery is a sport that uses a series of lower body coordination to maintain static balance in the upper body, which is then designed to shoot arrows at the target. This study aimed to determine differences in the physical condition of archery athletes in the provinces of East Java, West Java, and DKI Jakarta in the XX National Sports Week (PON) XX multi-event event in Papua. A total of 27 archery athletes as research subjects were divided into 3 groups: East Java, West Java, and Jakarta. Data collection used physical tests, including the Superman Back Hold (SBH) test, right (HGR), and left (HGL) hand grip strength and static balance tests. The results of the one-way ANOVA test showed significant results for all variables (p ≤ 0.05), and the Tukey’s HSD post hoc test showed that the East Java group had the best SBH, HGR, HGL, and statistical balance values compared to West Java and Jakarta. In conclusion, East Java Province has archery athletes with better physical conditions, superman back holds, hand grip strength, and static balance than the provinces of West Java and DKI Jakarta. Keywords: Archery, Hand Grip, Strenght, Superman Back Hold.

The Relationship Between FTP And VO2max Ability and Strength and Flexibility in Cyclists

The study aimed to investigate the relationship between VO2max and FTP in female road cyclists with strength (right/left-hand grip, back, leg), flexibility, and anthropometric variables. Descriptive statistics are presented as median and interquartile range. The median values of the participants were as follows: height 158.5 cm, body weight 54.9 kg, body fat percentage 19.6%, and body muscle mass 41.5 kg. The participants’ leg strength was measured at 70 kg, while their back strength was found to be 50 kg. Their right-hand grip strength was 29.1 kg, and their left-hand grip strength was 29.6 kg. The participant's flexibility was measured at 32 cm. Their VO2max was found to be 58.2 ml/kg/min, with a VO2max pulse of 189 beats/min and a VO2max workload of 262 watts. During the FTP test, the participant's mean pulse rate was 181 beats/min, mean cadence was 83 rpm, mean workload was 184 watts, normalized power was 185 watts, and relative power was 3.1 watts/kg. The study found a moderate positive correlation between VO2max and back strength and a strong negative correlation with flexibility. Additionally, a strong positive relationship was observed between VO2max workload value and body muscle mass, as well as right- and left-hand grip strength. No relationship was found between VO2max HR, AnT VO2, AnT HR, and AnT workload. Furthermore, the study found a moderate positive correlation between FTP value and body muscle mass and a very strong positive correlation with calendar age. The study also found significant correlations between mean FTP cadence and body muscle mass, as well as between mean FTP workload and body muscle mass. Additionally, a very strong positive correlation was observed between mean FTP workload and calendar age. Finally, a strong negative correlation was found between FTP relative strength and flexibility. The study concluded that as the strength of the back muscles in the group increased, so did their VO2max and FTP values, along with an increase in body muscle mass. The results suggest that back strength and body muscle mass are important variables for the participants in the study.

Gender Difference in the Relationship between Extrapulmonary Factors and Reduced Lung Function in Early Adulthood.

(1) Background: Reduced lung function in early adulthood is associated with future risks to health outcomes that have not been fully explored by gender. We investigated gender-specific relationships between lung function and extrapulmonary variables, assessing their potential as screening markers for respiratory dysfunction in young adults. (2) Methods: The participants were 151 medical students. Clinical data, handgrip strength (HS); body composition parameters such as skeletal muscle mass index (SMI), whole-body phase angle (WBPhA), and bone mineral content (BMC); and pulmonary function variables, vital capacity (VC), forced VC (FVC), and forced expiratory volume in one second (FEV1), were measured. (3) Results: FEV1 was significantly correlated with BMI, SMI, WBPhA, BMC, and both left and right HS (p < 0.0001, respectively) across all participants. According to gender, FEV1 had the strongest positive association with left HS in males (p < 0.0001) and BMC in females (p < 0.0001). The area under the curve for detecting the bottom quartile of FEV1 was 0.705 (cut-off 41.0 kg, sensitivity 91%) for left HS in males and 0.742 (cut-off 2.11 kg, sensitivity 81%) for BMC in females. (4) Conclusions: Gender-specific relationships between intrapulmonary and extrapulmonary factors such as left HS and BMC could be useful for screening suspected respiratory dysfunction in early adulthood.

Effectiveness of dance movement therapy and dance movement interventions on cancer patients' health-related outcomes: a systematic review and meta-analysis.

This review examined the effectiveness of using dance movement therapy (DMT) and dance movement interventions (DMIs) with cancer and palliative care patients. A systematic review and meta-analysis were conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Six databases were searched from inception to July 9, 2022, without limits on year or age. Searching was updated on July 10, 2023. The risk of bias was assessed by the Cochrane (RoB 2) and ROBINS-I tools. Meta-analyses were conducted to pool estimates of the effects of DMT and DMI on patients' health-related outcomes. A narrative synthesis of outcomes was performed where meta-analysis was not appropriate. Among a total of 16 studies included in this review, nine were randomized controlled trials and seven were non-randomized trials, with a total of 893 participants. Only six of these studies were fully or partially described as true DMTs (some with less clarity than others), whereas the majority (n = 10) were DMIs with unclear therapeutic alignment. Most studies focused on female patients with breast cancer. Cancer patients undergoing palliative care received little attention. The overall risk of bias from the evaluated studies was high. Meta-analysis of two trials revealed that DMTs had no effect on QOL in cancer patients (SMD - 0.09, 95% CI - 0.21-0.40, P = 0.54), while narrative analysis and non-randomized trials showed no overall effect of DMTs on anxiety, depression, body image, self-esteem, or sleep disturbance but significant positive effects on perceived stress, pain severity, and pain interference. DMIs had significant positive effects on cancer patients' depression (SMD - 0.53, 95% CI - 0.93 to - 0.14, P = 0.008) and fatigue (SMD - 0.42, 95% CI - 0.70 to - 0.14, P = 0.003). DMI trials synthesized narratively showed an effect on patients' body image, self-esteem, physical function, right and left handgrip strength, life satisfaction, and the mental component of QOL. Both DMT and DMIs had promisingeffects on severalhealth outcomes, but results were inconsistent, and the evidence was weak. The reviewed studies' low evidence quality and small sample sizes affected the findings' robustness and reliability. Large-scale, high-quality randomized controlled trials with sufficient sample sizes, and clear and veracious DMT and DMI protocols and data are required to provide more credible research evidence and influence practice.

Muscle strength and body composition in obese adults following nine months of yoga or nutrition advice: A comparative controlled trial

IntroductionMuscle strength is impaired in obese persons due to low physical activity, obesity-related modifications in muscle morphology and as a consequence of calorie regulation (where applicable). Previously decreased BMI and increased hand grip strength was reported following a short duration yoga intervention in obese adults. MethodsThe present comparative controlled study was conducted on two hundred and ninety seven obese adults (BMI ≥25 Kg/M2) aged between 20 and 59 years, to determine the effects of nine months of yoga or nutrition advice on muscle strength and body composition. Participants were assessed for bilateral hand grip strength, leg and back strength, and body composition at baseline, after 3 months, 6 months and 9 months of yoga or nutrition advice. BMI-adjusted bilateral hand grip strength and leg and back strength were calculated. ResultsIn the linear mixed model analyses, there was a significant interaction effect of Time X Groups for (i) right hand grip strength (F3,668.465 = 9.297, p < 0.001), (ii) left hand grip strength (F3,673.408 = 14.469, p < 0.001), (iii) BMI-adjusted right hand grip strength (F3,650.542 = 9.954, p < 0.001) and (iv) BMI-adjusted left hand grip strength (F3,655.518 = 13.853, p < 0.001). Bonferroni corrected post-hoc analyses (padj < 0.05; in all cases) showed a significant increase in (i) bilateral hand grip strength and (ii) BMI-adjusted right and left hand grip strength in the yoga group while a decrease in (i) bilateral hand grip strength and (ii) BMI-adjusted right and left hand grip strength in the nutrition advice group. ConclusionYoga practice appears to protect and increase upper limb muscle strength in obese adults.

The effects of inspiratory muscle training on biomarkers of muscle damage in recovered COVID-19 patients after weaning from mechanical ventilation.

Background: COVID-19 patients experience respiratory muscle damage, leading to reduced respiratory function and functional capacity often requiring mechanical ventilation which further increases susceptibility to muscle weakness. Inspiratory muscle training (IMT) may help mitigate this damage and improve respiratory function and functional capacity. Methods: We studied the effects of IMT on muscle damage biomarkers, respiratory function, and functional capacity in COVID-19 recovered young adults, successfully weaned from mechanical ventilation. Participants were randomly allocated to either an IMT (n = 11) or control (CON; n = 11) intervention for 4weeks. The IMT group performed 30 dynamic inspiratory efforts twice daily, at 50% of their maximal inspiratory mouth pressure (PMmax) while the CON group performed 60 inspiratory efforts at 10% of pMmax daily. Serum was collected at baseline, week two, and week four to measure creatine kinase muscle-type (CKM), fast skeletal troponin-I (sTnI) and slow sTnI. Results: Time × group interaction effects were observed for CKM and slow sTnI, but not for fast sTnI. Both were lower at two and 4weeks for the IMT compared to the CON group, respectively. Time × group interaction effects were observed for forced expiratory volume in 1s, forced vital capacity, PMmax and right- and left-hand grip strength. These were higher for the IMT compared to the CON group. Conclusion: Four weeks of IMT decreased muscle damage biomarkers and increased respiratory function and grip strength in recovered COVID-19 patients after weaning from mechanical ventilation.

Analysis of the Dominant Aspects of Libero’s Basic Skills

The physical fitness parameters of players in the libero position need to be measured to maintain performance with training that is appropriate to the needs of supporting movement performance as a libero. The aim of this research is to analyze the basic skills of Libero players. This is quantitative research that uses skill tests as a research instrument. The test instruments used include grip strength tests, sit-and-reach, running, push-up, sit-up, back-up, and vertical jumps. The research population is volleyball players in the position of libero in the Volleyball Student Activity Unit at Surabaya State University. The sampling technique used was a total sampling of 12 students. The data was analyzed descriptively and quantitatively to determine the average skill characteristics of Libero players. The research results show that the average sit and reach test measurement result for male players is 37.93 and for female players is 40.70. The average left-hand grip strength test result for men is 39.43 and for women is 26.8. The average right-hand grip strength test result for men is 41.29 and for women is 28.40. The average result of the push-up test for men is 34.29, and for women, it is 38.80. The average result of the sit-up test for male players is 44.14, and for females, it is 54.00. The average back-up test result for male players is 76.00, and for women, it is 76.00. The average running test result for men is 9.81 and for women is 9.64. The average result of the vertical jump test for men is 55.14 cm, and for women, it is 48.80 cm. The results of this research are useful for trainers as a consideration in preparing special physical training programs that suit the characteristics of liberos.

Genetic causality and site-specific relationship between sarcopenia and osteoarthritis: a bidirectional Mendelian randomization study.

Background: Previous studies demonstrated a controversial relationship between sarcopenia (SP) and osteoarthritis (OA) and their genetic causality is unclear. Thus, we conducted a Mendelian randomization (MR) analysis to evaluate the possible causal association between sarcopenia-related traits (appendicular lean mass (ALM), grip strength, usual walking pace) and OA. Method: We used pooled genetic data from the UK Biobank for ALM(n = 450,243), left-hand grip strength (n = 461,026), right-hand grip strength (n = 461,089) and usual walking pace (n = 459,915). Moreover, summary statistics for OA were obtained from the latest study conducted by the Genetics of Osteoarthritis Consortium, including all OA (n = 826,690), hand OA (n = 303,7782), hip OA (n = 353,388) and knee OA (n = 396,054). The primary method for estimating causal effects was the inverse-variance weighted (IVW) method, with the utilizing of false discovery rate adjusted p values (P FDR). Additional MR methods such as MR-Egger regression, MR pleiotropy residual sum and outlier (MR-PRESSO), weighted median were employed as supplementary analyses. Results: We discovered ALM (odds ratio (OR) = 1.103, 95% confidence interval (CI) = 1.052-1.156, P FDR = 2.87E-04), hand grip strength (left, IVW OR = 0.823, 95% CI = 0.712 to 0.952, P FDR = 0.020; right, OR = 0.826, 95% CI = 0.718 to 0.950, P FDR = 0.020), and usual walking pace (OR = 0.339, 95% CI = 0.204 to 0.564, P FDR = 2.38E-04) were causally associated with OA risk. In the reverse MR analysis, we identified a causal effect of OA on ALM (β = -0.258, 95% CI = -0.369 to 0.146, P FDR = 0.6.07E-06), grip strength (left, β = -0.064, 95% CI = -0.104 to 0.024, P FDR = 0.002; right, β = -0.055, 95% CI = -0.095 to 0.014, P FDR = 0.008), and usual walking pace (β = -0.104, 95% CI = -0.147 to 0.061, P FDR = 1.61E-05). Conclusion: This present study suggests an obvious causality of SP on OA, with condition exhibiting site-specific effects, while evidence was also provided for the causal effect of OA on SP.

Impacts of the Surya Namaskar on Body Composition and Physiological Parameters among Yoga and Non Yoga Professionals: A Quasi-experimental Study

Introduction: Surya Namaskar (SN) (also known as Sun Salutation) in the Bihar School of Yoga tradition comprises eight different postures completed in twelve steps sequentially. There are different views and schools of SN according to various traditions. Several studies have been conducted to demonstrate the effects of SN on the physiological, physical, and mental aspects of practitioners; however, its comparative effect on Yoga professionals and Non Yoga professionals has not been extensively explored. Aim: To determine the impacts of SN on body composition and physical and physiological variables among Yoga and Non Yoga professionals. Materials and Methods: This was a quasi-experimental study conducted at Morarji Desai National Institute of Yoga, New Delhi, India from March 2021 to May 2021. The study involved three groups with 10 subjects each: the Non Yoga Professional Control group (NYPC), the Non Yoga Professional Surya Namaskar group (NYPS), and the Yoga Professional Surya Namaskar group (YPS). The NYPS and YPS groups practiced 12 rounds of SN, totaling 24 minutes daily for 5 days a week over 6 weeks. Height, weight, Body Mass Index (BMI), Heart Rate (HR), Systolic Blood Pressure (SBP), Diastolic Blood Pressure (DBP), Breathe Holding Time (BHT), Right Hand Grip Strength (RHGS), Left Hand Grip Strength (LHGS), Flexibility, Muscle mass, Percentage Body Fat (PBF%), total Body Fat (BF), Bone Mass (BM), Waist to Hip Ratio (WHR), and Basal Metabolic Rate (BMR) were recorded on the first day and after six weeks. GraphPad Instat Windows-based software, version 3.0, was used to complete the statistical analysis. Intergroup comparison was performed using Repeated Measure Analysis of Variance (ANOVA). Pre- and post-comparisons were made using t-tests. The level of significance was set at p≤0.05. Results: A significant reduction was observed in HR (p≤0.05), SBP (p≤0.01), Pulse Pressure (PP) (p≤0.05), Double Product (DoP) (p≤0.05), and Rate Pressure Product (RPP) (p≤0.05) following SN in the NYPS group. A significant reduction was observed in SBP (p≤0.01), DBP (p≤0.05), and MBP (p≤0.01) following Surya Namaskar practice in the YPS group. BHT (p≤0.05), RHGS (p≤0.05), LHGS (p≤0.05), and flexibility (p≤0.01) significantly increased following SN in the NYPS group. Flexibility was significantly increased (p≤0.05) following SN in the YPS group. PBF and BF decreased significantly (p≤0.001) following SN in the NYPS group. Conclusion: The SN has demonstrated effects on the physical, physiological, and therapeutic aspects of practitioners. The present study established that the practice of SN improves body composition and cardiovascular function with increased efficiency, potentially aiding in the prevention of lifestyle-related cardiovascular diseases.

THE ASSOCIATIONS OF HANDGRIP STRENGTH AND ANTHROPOMETRIC MEASUREMENTS WITH UPPER LIMB BODY FAT MASS IN OLDER ADULTS

Abstract Body Fat Mass (BFM) is a crucial body composition measurement serving as a predictor for various health conditions and mortality in older adults. However, limited research has been conducted to investigate how upper limb BFM associates with anthropometric measurements and handgrip strength (HGS) in older adults. In this cross-sectional study, 119 older adults, ranging from 60 to 96 years of age (93 women, 26 men; mean age 74.71 ± 7.35 years), were assessed. Body composition was evaluated using the portable Bioelectrical Impedance Analysis (BIA) device, InBody S10, and average HGS was measured on each side using a hand grip dynamometer (JAMAR 5030J1). Multiple linear regression analysis was performed and found a significant, positive association for age (β = 0.048 , p = 0.024), height (β = 0.649, p = 0.024), and BMI (β = 1.371, p &amp;lt; 0.001) with left arm BFM, while weight and left HGS showed a negative association (β = -0.152, p = 0.007; β = -0.070 , p = 0.004, respectively). Similar trends were seen for the right arm. However, height and right HGS became statistically insignificant (β = 0.536, p = 0.069; β = -0.046 , p = 0.054, respectively) for right arm BFM only. These results show that the independent variables may have the ability to predict upper limb BFM in older adults without the need for body composition measurement methods (e.g., BIA). Further research is warranted to examine the true predictive capacity of the independent variables in relation to upper limb BFM.

Increased muscle mass increases risks of intervertebral disc degeneration: a two-sample Mendelian randomization study

To investigate the causal relationship between sarcopenia (SP) and intervertebral disc degeneration (IVDD) using two-sample Mendelian randomization analysis. Genome-wide association study (GWAS) databases of SP (lean body mass, right and left hand grip strength) and IVDD were obtained. The single nucleotide polymorphisms (SNPs) strongly associated with exposure were obtained as an instrumental variable. After conservatively removing two confounders (smoking and sedentary life style), the causal relationship between SP and IVDD was assessed using Mendelian randomization analyses through the inverse variance weighting (IVW), weighted median (WM) and MR-Egger methods. The consistency and accuracy of the results were verified by MR-PRESSO, double validation, negative control, heterogeneity and diversity tests. A total of 570 SNPs associated with lean muscle mass, 97 with strong right hand grip strength, and 79 with strong left hand grip strength were included in the analysis. The results showed that lean muscle mass had a significant positive correlation with IVDD (IVW: OR=1.139, 95% CI: 1.076-1.204, P=6.619e-6) and right hand grip strength had a possible positive correlation with IVDD. After reanalysis in MR-PRESSO and selection of a new IVDD database, the results remained largely consistent with the previous results. Increased muscle mass may increase the risk of intervertebral disc degeneration.

Biological ageing and the risk of decreased handgrip strength among community-dwelling older adult Indians: a cross-sectional study

BackgroundEvidence from the literature demonstrates that the risk of decreased handgrip strength is associated with various health issues, particularly in older persons. To make judgments regarding their general health condition that are well-informed for longevity, it is crucial to assess the risk level of decreased handgrip strength among community-dwelling older adult Indians. However, no study has examined the relationship between biological aging and the risk of decreased handgrip strength in Indian men and women aged 60 and older. The goal of the current study was to fill this gap in the literature.MethodsIn this cross-sectional study, we included 31,464 (15,098 men and 16,366 women) community-dwelling older adult Indians aged 60 years and older using data from the Longitudinal Aging Study in India (LASI). The LASI is the world’s most extensive and India’s first multidisciplinary, internationally harmonized, longitudinal aging study. It has enrolled 72,250 individuals aged 45 and above across all 28 states and 8 union territories of India. Secondary analysis of biological ageing was performed by stratifying for age groups (60–64, 65–69, 70–74, 75–79, 80–84, and 85 + years) for both genders. The dominant right and nondominant left handgrip strength was assessed using the portable Smedley’s Hand Dynamometer. All individuals had a dominant right hand. The adjusted logistic regression analysis assessed the association between biological ageing and the risk of decreased handgrip strength for both genders.ResultsCompared to those between the ages of 60–64, those at age 65 and those aged 85 and above had 1-fold and 12-fold odds of decreasing handgrip strength, respectively. Men 85 years or older had a 12-fold higher chance than women in the same age group of having decreased handgrip strength.ConclusionsThe results indicate that community-dwelling older adult Indians aged 65 years and older are significantly associated with a higher risk of decreased handgrip strength, especially among older men. The results of this study can help assess and implement handgrip strength measurement in medicine for older Indians as part of regular admission assessment, particularly for older men.

Causal associations between hand grip strength and pulmonary function: a two-sample Mendelian randomization study

BackgroundSeveral observational studies have reported an association between hand grip strength (HGS) and pulmonary function (PF). However, causality is unclear. To investigate whether HGS and PF are causally associated, we performed Mendelian randomization (MR) analyses.MethodsWe identified 110 independent single nucleotide polymorphisms (SNPs) for right-hand grip strength (RHGS) and 103 independent SNPs for left-hand grip strength (LHGS) at the genome-wide significant threshold (P < 5 × 10−8) from MRC-IEU Consortium and evaluated these related to PF. MR estimates were calculated using the inverse-variance weighted (IVW) method and multiple sensitivity analyses were further performed.ResultsGenetical liability to HGS was positively causally associated with forced vital capacity (FVC) and forced expiratory volume in one second (FEV1), but not with FEV1/FVC. In addition, there was positive causal association between RHGS and FVC (OR=1.519; 95% CI, 1.418-1.627; P=8.96E-33), and FEV1 (OR=1.486; 95% CI, 1.390-1.589; P=3.19E-31); and positive causal association between LHGS and FVC (OR=1.464; 95% CI, 1.385-1.548; P=2.83E-41) and FEV1 (OR=1.419; 95% CI, 1.340-1.502; P=3.19E-33). Nevertheless, no associations were observed between RHGS and FEV1/FVC (OR=0.998; 95% CI, 0.902-1.103; P=9.62E-01) and between LHGS and FEV1/FVC (OR=0.966; 95% CI, 0.861-1.083; P=5.52E-01). Similar results were shown in several sensitivity analyses.ConclusionOur study provides support at the genetic level that HGS is positively causally associated with FVC and FEV1, but not with FEV1/FVC. Interventions for HGS in PF impairment deserve further exploration as potential indicators of PF assessment.

Causality between urate levels with sarcopenia-related traits: a bi-directional Mendelian randomization study.

Observational studies have suggested associations between serum urate levels and sarcopenia, but the causality underlying this correlation remains uncertain. The principal objective of this study is to investigate a causal relationship of serum urate levels with sarcopenia-related traits (hand grip strength, lean mass, walking pace) using bidirectional two-sample Mendelian randomization (MR) approach. The utilization of MR methodology serves to minimize bias caused by reverse causality and confounding factors from observational studies. The summary statistics of serum urate levels were derived from a cohort consisting of 288,659 individuals participating in CKDGen study. The parameters of right-hand grip strength (N=461,089), left-hand grip strength (N=461,026), appendicular lean mass (ALM) (N=450,243), whole-body lean mass(N=454,850),right-leg fat-free mass(FFM;N=454,835),left-leg FFM(N=454,805), right-arm FFM(N=454,753),left-arm FFM(N=454,672) and walking pace (N=459,915)were sourced from the UK Biobank. MR analysis was conducted utilizing inverse variance weighted (IVW), weighted median, and MR-Egger to evaluate causality. Sensitivity analysis was performed using Cochran's Q test, MR-Egger intercept test, leave-one-out analysis and the funnel plot. IVW estimates demonstrated that serum urate levels exhibited no causal association with sarcopenia-related traits. In the inverse MR investigation, we had exclusively discerned an inverse correlation between walking pace and serum urate levels. No compelling evidence had surfaced to substantiate any association of other sarcopenia-related traits with serum urate. Supplemental MR methods consistently validated the findings obtained from the primary analysis. Sensitivity analysis demonstrated the robustness of findings. Our MR study revealed the absence of the bidirectional causal relationship between serum urate levels and sarcopenia. It is imperative to acknowledge that advanced age and an individual's health status are pivotal determinants influencing urate level and the initiation and advancement of sarcopenia. However, it is worth underscoring that these aspects remain unexamined within the purview of this study. Thus, future investigations should delve deeper into these intricate facets.

Analysis of Physical Performance Parameters According to Playing Positions of Amputee Football Players

This study examines the physical performance parameters of amputee football players during a season according to their playing positions. A total of 16 amputee football players participated in this study. Hand grip strength, back, leg, arm strength, visual reaction, 10-20-30m sprint, flexibility tests, resting heart rate, and maximal heart rate measurements performed at the beginning, mid-season, and the end of the season. Seasonally significant differences were determined in defenders' left-hand grip, back, leg, and arm strength tests, and 10-20-30m sprint test scores. Moreover, seasonal significant differences were found in the test scores of the back, leg, arm strength, right-hand visual reaction, 10-20-30m sprint, and flexibility of midfield players. Significant differences were found in strikers' right- and left-hand grip, back, leg, and arm strength, and 20-30m sprints test mean scores. It was determined that the annual training plan had different positive contributions to the players' physical performance according to their playing positions. During the competition season, performance changes were determined by the midfielders' reaction, strength, flexibility, and sprint and the strength and sprint performance of the forwards and defenders.

Association between sarcopenia-related traits and cardiovascular diseases: a bi-directional Mendelian randomization study.

The two geriatric diseases, sarcopenia and cardiovascular disease (CVD), often coexist, yet the causal relationship is unclear. However, few studies focus on the effect of muscle mass on CVD. This comprehensive study is dedicated to unearthing the potential connection between sarcopenia-related traits and CVD at the genetic level. A two-sample bi-directional Mendelian randomization (MR) study was conducted. In the first stage, we performed MR analysis regarding coronary heart disease (CHD), stroke, and myocardial infarction (MI) as exposure factors to reveal their effect on appendicular lean mass (ALM) and hand grip strength. In the second stage, we reverse the position of exposures and outcomes. The inverse variance weighted (IVW) method was used as the primary approach to reveal the potential causation between the exposure and outcome. The results of the IVW method revealed a negative causal effect of ALM on CHD (OR = 0.848, 95% CI = 0.804 to 0.894, p = 8.200E-10), stroke (OR = 0.931, 95% CI = 0.890 to 0.975, p = 2.220E-03), and MI (OR = 0.810, 95% CI = 0.694 to 0.901, p = 1.266E-13). Additionally, the left-hand grip strength is a significant protective factor for CHD (OR = 0.737, 95% CI = 0.601 to 0.904, p = 3.353E-03) and MI (OR = 0.631, 95% CI = 0.515 to 0.765, p = 2.575E-06), but is not causally linked to the stroke (OR = 0.971, 95% CI =0.829 to 1.139, p = 0.720). Meanwhile, the same conclusion about the effect of right-hand grip strength on CHD (OR = 0.681, 95% CI = 0.558 to 0.832, p = 1.702E-05), MI (OR = 0.634, 95% CI = 0.518 to 0.776, p = 9.069E-06), and stroke (OR = 1.041, 95% CI = 0.896 to 1.209, p = 0.604) was obtained. However, no significant causal effect of CVD (CHD, stroke, MI) on sarcopenia-related traits (ALM, handgrip strength) was found. There is a unidirectional causal relationship between sarcopenia and CVD. The loss of muscle mass and strength has a significant causal role in promoting the occurrence and development of CVD, providing a reference for the prevention and treatment of comorbidities in older people.

Influence of body and hand anthropometric characteristics on handgrip strength in young Nigerian women

Background and aimWomen are well known for having lower handgrip strength (HGS) compared to men. However, factors contributing to lower HGS in women remain unclear. This study investigated the influence of body and hand anthropometric characteristics (HAC) on HGS among young Nigerian undergraduate women.MethodsApparently healthy 500 young female adults from a Nigerian University were recruited conveniently. Age and physical characteristics were recorded. Right and left (R&L) HGS were measured using an electronic dynamometer. HAC including R&L arm girth (ArG), forearm girth (FaG), wrist girth (WrG), finger span (FSp), finger breath (FBr), finger length (FLg) and palm length (PLg) were measured. Data were analysed using descriptive and inferential statistics. Alpha level was set at p < 0.05.ResultsThe mean age of the participants was 22.46 ± 3.72 years. Age and body mass index (BMI) contributed about 20.0 and 12.0% to the prediction of HGS, respectively. Similarly, R&L HAC: ArG, FaG, WrG, FSp, FBr, FLg and PLg contributed about 22.8 and 14.8% to the prediction of HGS, respectively. Significant correlations occurred between HGS and each of BMI, R&L HAC (p < .05). Furthermore, significant correlations were also found between age and each of R&L HAC (p < .001).ConclusionsAge, BMI and HAC have significant influence on the HGS of young Nigerian undergraduate women. Hence, physical factors such as weight, height, BMI, and hand anthropometric measurements are recommended as part of routine assessment for effective rehabilitation plans in the care of women with hand disability or poor hand function.

Causality between sarcopenia-related traits and major depressive disorder: A bi-directional, two-sample Mendelian randomized study.

Observational studies have demonstrated an association between sarcopenia and depression. However, these studies may be influenced by confounding factors, and the causal relationship between sarcopenia and major depressive disorder (MDD) remains unclear. This study aimed to apply the Mendelian randomization (MR) method to address confounding factors and assess the causal effect of sarcopenia on MDD. A two-way, two-sample MR method was employed in this study. Instrumental variables of genome-wide significance level were obtained from the open large-scale genome-wide association study summary data. MR analysis was conducted using inverse variance weighted, MR-Egger, and weighted median methods. The reliability of the results was verified using the heterogeneity test, pleiotropy test, and leave-one-out method for sensitivity analysis. Grip strength (right-hand grip strength: odds ratio [OR] = 0.880, 95% confidence interval [CI] 0.786-0.987, P = .027; left-hand grip strength: OR = 0.814, 95% CI 0.725-0.913, P < .001) and usual walking pace (OR = 0.673, 95% CI 0.506-0.896, P = .007) exhibited a direct causal effect on MDD. MDD had a significant causal effect on appendicular lean mass (β = -0.065, 95% CI -0.110, -0.019, P = .005). There was a causal relationship between sarcopenia-related traits and MDD. Loss of muscle strength, rather than skeletal muscle mass, is correlated with an increased risk of MDD. Furthermore, individuals with MDD are more likely to experience loss of skeletal muscle mass.

Causal effects of specific gut microbiota on musculoskeletal diseases: a bidirectional two-sample Mendelian randomization study.

Recent observational studies and clinical trials demonstrated an association between gut microbiota and musculoskeletal (MSK) diseases. Nonetheless, whether the gut microbiota composition has a causal effect on the risk of MSK diseases remains unclear. Based on large-scale genome-wide association studies (GWAS), we performed a two-sample Mendelian randomization (MR) analysis to investigate the causal relationship between gut microbiota and six MSK diseases, namely osteoporosis (OP), fracture, sarcopenia, low back pain (LBP), rheumatoid arthritis (RA), and ankylosing spondylitis (AS). Instrumental variables for 211 gut microbiota taxa were obtained from the largest available GWAS meta-analysis (n = 18,340) conducted by the MiBioGen consortium. And the summary-level data for six MSK diseases were derived from published GWAS. The inverse-variance weighted (IVW) method was conducted as a primary analysis to estimate the causal effect, and the robustness of the results was tested via sensitivity analyses using multiple methods. The Bonferroni-corrected test was used to determine the strength of the causal relationship between gut microbiota and various MSK diseases. Finally, a reverse MR analysis was applied to evaluate reverse causality. According to the IVW method, we found 57 suggestive causal relationships and 3 significant causal relationships between gut microbiota and MSK diseases. Among them, Genus Bifidobacterium (β: 0.035, 95% CI: 0.013-0.058, p = 0.0002) was associated with increased left handgrip strength, Genus Oxalobacter (OR: 1.151, 95% CI: 1.065-1.245, p = 0.0003) was correlated with an increased risk of LBP, and Family Oxalobacteraceae (OR: 0.792, 95% CI: 0.698-0.899, p = 0.0003) was linked with a decreased risk of RA. Subsequently, sensitivity analyses revealed no heterogeneity, directional pleiotropy, or outliers for the causal effect of specific gut microbiota on MSK diseases (p > 0.05). Reverse MR analysis showed fracture may result in a higher abundance of Family Bacteroidales (p = 0.030) and sarcopenia may lead to a higher abundance of Genus Sellimonas (p = 0.032). Genetic evidence suggested a causal relationship between specific bacteria taxa and six MSK diseases, which highlights the association of the "gut-bone/muscle" axis. Further exploration of the potential microbiota-related mechanisms of bone and muscle metabolism might provide novel insights into the prevention and treatment of MSK diseases.

Tracking handgrip strength asymmetry from childhood to mid-life.

Determine if asymmetric handgrip strength exists in childhood and adulthood and quantify the degree of tracking of handgrip strength asymmetry over time. Participants from the Childhood Determinants of Adult Health Study had their right and left handgrip strength measured using handgrip dynamometry in childhood (1985: 9-15 y), young adulthood (2004-06: 26-36 y) and/or mid-adulthood (2014-19: 36-49 y). Handgrip strength asymmetry was calculated as: strongest handgrip strength/strongest handgrip strength on the other hand. Participants were categorised based on the degree of their asymmetry (0.0%-10.0%, 10.1%-20.0%, 20.1%-30.0%, >30.0%). Tracking was quantified using Spearman's correlations and log binomial regression. Handgrip strength asymmetry was present in childhood and adulthood (>30.0% asymmetry: childhood = 6%, young adulthood = 3%, mid-adulthood = 4%). Handgrip strength asymmetry did not track between childhood and young- (r = 0.06, 95% CI = -0.02, 0.12) and mid-adulthood (r = 0.01, 95% CI = -0.09, 0.10). Tracking was more apparent between young- and mid-adulthood (r = 0.16, 95% CI = 0.09, 0.22). Participants with >30.0% asymmetry were at greater risk to maintain this status between childhood and young- (RR = 3.53, 95% CI = 1.15, 10.87) and mid-adulthood (RR = 2.14, 95% CI = 0.45, 10.20). Although handgrip strength asymmetry tracked relatively poorly, asymmetric handgrip strength was apparent in children and adults. Handgrip strength asymmetry does not exclusively affect older adults and should be considered in protocols to better understand its role across the life course.