You have accessJournal of UrologyUrodynamics/Lower Urinary Tract Dysfunction/Female Pelvic Medicine: Female Incontinence: Therapy II (MP52)1 Sep 2021MP52-10 CLINICAL STUDY OF A NEUROMODULATIVE SLING SYSTEM WITH TVT-XO PROCEDURE IN THE TREATMENT OF MIXED URINARY INCONTINENCE Hai-Hong Jiang, Xiao-Liang Zhu, Yasmeen Bano, Qi-Xiang Song, Kang-Li Deng, Jiahui Liu, Hongbing Liao, and Meihao Wang Hai-Hong JiangHai-Hong Jiang More articles by this author , Xiao-Liang ZhuXiao-Liang Zhu More articles by this author , Yasmeen BanoYasmeen Bano More articles by this author , Qi-Xiang SongQi-Xiang Song More articles by this author , Kang-Li DengKang-Li Deng More articles by this author , Jiahui LiuJiahui Liu More articles by this author , Hongbing LiaoHongbing Liao More articles by this author , and Meihao WangMeihao Wang More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002082.10AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Mixed urinary incontinence (MUI) is a relatively complex medical condition. To evaluate the safety and effectiveness of the neuromodulative sling system with TVT-XO procedure in MUI, we performed surgical treatment and short-term observation on 11 women with severe MUI by using a new neuromodulative sling system combined with a new anti-incontinence TVT-XO suspension procedure. METHODS: A total of 11 adult female patients with severe MUI were included under the following screening criteria: leakage point pressure < 60 cm H2O, severe bladder urgent symptoms (overactive bladder symptom score(OABSS) >12), and no significant improvement after pelvic floor exercise and related medications. The principle of TVT-XO suspension is that two sling tapes crossover stereoscopic suspension of the urethra. The microelectric stimulating lead along the shell of the left suprapubic sling was inserted below the middle and proximal suburethral urethra. The stimulator was then attached to the lead. During neuromodulation after implantation, the urgency can be regulated through feedback. RESULTS: All 11 patients underwent TVT-XO procedure along with the neuomodulative sling system implantation successfully. With neuromodulation treatment one month after surgery, it indicated significant improvements in MUI symptoms, including the short version of questionnaire IIQ7 and the OABSS score (p < 0.05). CONCLUSIONS: Our preliminary study demonstrated the TVT-XO sling procedure along with a new neuromodulative sling can simultaneously improve patients' urinary incontinence and urgency with no serious complications. The limitations of the study include the small number of patients and the short time of the observation. We expected a large-scale trial and long-term observation of the safety and effectiveness. Source of Funding: Zhejiang Provincial Natural Science Foundation of China (No. WY20H050001), Zhejiang Provincial Medical and Health Technology Program projects of China (Nos. 2018PY031, 2018KY512, and 2019KY101), and National Natural Science Foundation of China (No. 81670695) © 2021 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 206Issue Supplement 3September 2021Page: e933-e933 Advertisement Copyright & Permissions© 2021 by American Urological Association Education and Research, Inc.MetricsAuthor Information Hai-Hong Jiang More articles by this author Xiao-Liang Zhu More articles by this author Yasmeen Bano More articles by this author Qi-Xiang Song More articles by this author Kang-Li Deng More articles by this author Jiahui Liu More articles by this author Hongbing Liao More articles by this author Meihao Wang More articles by this author Expand All Advertisement Loading ...