This study is concerned with numerical simulation of the strain due to glaciation and glacial melting, when a magma zone (a layer containing inclusions of magma and magma cumulates) is present at the crust–mantle boundary. According to analytical solutions of this problem that involves viscous relaxation of an uncompensated depression at the place of the molten glacier, the depth to the zone of increased shear stresses beneath the depression is proportional to its width, while the relaxation duration is proportional to viscosity of the lithosphere and is a few thousand years. These fundamental estimates are corroborated by our numerical simulation. According to it, the magma zone at the Moho boundary shields the zone of increased shear stresses, limiting it from below. The maximum values (12–25 MPa) with glacial thickness 500–1000 m are reached at the top of this layer of low viscosity. The directions of maximum compression (s1) as calculated for the time after the melting indicate that the magma that rises along dikes is displaced from the center of the magma lens toward its periphery. It is found that glacial unloading makes the dipping faults in the crust above the low-viscosity layer attractors for the rising magma. Glacial unloading accelerates, by factors of a few times, the magma generation in the mantle that occurs following the mechanism of adiabatic decompression, as well as facilitating the accumulation of mantle fluids in the zone of increased shear stresses at the boundary of the low viscosity layer. The magma traverses this deep fluid collector and increases the intensity and explosivity of eruptions at the beginning of an interglacial period. Our numerical simulation results are in general agreement with published data on Early Holocene volcanic eruptions that occurred after the second phase of the Late Pleistocene glaciation in Kamchatka.