Lavender Essential Oil Research Articles

Aromatic Serenity: How Lavender Eases Stress and Anxiety - A Literature Review

In today's fast-paced society, rising stress levels necessitate effective management strategies. While pharmacological treatments are common, their side effects have spurred interest in alternative therapies, particularly those rooted in natural remedies. Lavender (Lavandula angustifolia), long esteemed for its calming properties, has emerged as a promising non-pharmacological option. Historical use in herbal medicine for anxiety and stress-related disorders has inspired modern scientific research to explore its potential. This review synthesizes recent studies on lavender essential oil, examining its mechanisms—such as neurotransmitter modulation—and its effectiveness in diverse settings, from reducing stress among healthcare professionals to improving sleep quality. Despite promising results, limitations like small sample sizes and variability in application methods highlight the need for more rigorous research to establish lavender's efficacy and optimize its therapeutic use in stress management and mental health care.

Development of Alginate Hydrogels Incorporating Essential Oils Loaded in Chitosan Nanoparticles for Biomedical Applications

A hybrid alginate hydrogel–chitosan nanoparticle system suitable for biomedical applications was prepared. Chitosan (CS) was used as a matrix for the encapsulation of lavender (Lavandula angustifolia) essential oil (LEO) and Mentha (Mentha arvensis) essential oil (MEO). An aqueous solution of an acidic Natural Deep Eutectic Solvent (NADES), namely choline chloride/ascorbic acid in a 2:1 molar ratio, was used to achieve the acidic environment for the dissolution of chitosan and also played the role of the ionic gelator for the preparation of the chitosan nanoparticles (CS-NPs). The hydrodynamic diameter of the CS-MEO NPs was 130.7 nm, and the size of the CS-LEO NPs was 143.4 nm (as determined using Nanoparticle Tracking Analysis). The CS-NPs were incorporated into alginate hydrogels crosslinked with CaCl2. The hydrogels showed significant water retention capacity (>80%) even after the swollen sample was kept in the aqueous HCl solution (pH 1.2) for 4 h, indicating a good stability of the network. The hydrogels were tested (a) for their ability to absorb dietary lipids and (b) for their antimicrobial activity against Gram-positive and Gram-negative foodborne pathogens. The antimicrobial activity of the hybrid hydrogels was comparable to that of the widely used food preservative sodium benzoate 5% w/v.

Improving Egg Production, Quality and Eggshell Hygiene by Supplementation of Sage (Salvia officinalis) and Lavender (Lavandula angustifolia) Essential Oils

ABSTRACT Objective: This study was performed to evaluate the effects of sage (Salvia officinalis) and lavender (Lavandula angustifolia) essential oils (EO) supplementation into drinking water on egg production, quality and eggshell hygiene in laying hens. Material and Methods: A total of 300 Nick Brown laying hens between 30 and 38 of age were used in a completely randomized design in three treatments and ten replicates. The treatments consisted of: control group, sage EO, lavender EO supplementation group. EOs were supplemented into drinking water (0.3 mL/L). Results: A lower value of egg production, egg weight, egg mass and deteriorations in feed efficiency, eggshell breaking strength and thickness were observed in lavender EO group (P

Scented solutions: Harnessing lavender essential oil liposomes for enhanced plywood performance

A wood-based panel that is both healthy and environmentally friendly has been developed utilizing the aromatic odor emitted by lavender essential oil. Liposomes were employed to encapsulate the lavender essential oil, resulting in a favorable loading effect and facilitating the control of odor release. Chitosan was used to encapsulate the lavender essential oil liposomes and then cross-linked with phosphate ions to form hydrogel balls, which improved the antioxidant performance and thermal stability of the lavender essential oil liposomes, achieving a 100 % encapsulation rate at optimal dosages. In order to investigate the effect of composite liposomes on the emission of volatile organic compounds (VOCs) that cause odors, plywood was used as the subtract for their application. Panels treated with essential oil liposome hydrogel spheres exhibited improved mechanical properties, with a 4.3 % increase in average MOR and a 15.7 % increase in average bonding strength compared to control panels. The release of aromatic VOCs was prolonged after plywood had been treated with essential oil liposome hydrogel balls, but the release of phenolic odor VOCs was significantly suppressed. This study provides a new solution for reducing plywood odor emissions.

Aromatherapy Using Lavender Oil Effectiveness on Pain and Anxiety After C-Section: A Randomized Controlled Trial.

Managing postoperative setting, regarding pain and anxiety after cesarean delivery is crucial for the mother's recovery, her emotional well-being, mother-infant bonding and initiating breastfeeding. Although some research have suggested that aromatherapy with lavender essential oil can be effective in reducing pain and anxiety in various medical settings, the efficacy of lavender aromatherapy in the postoperative setting after cesarean delivery is less well-studied. We aimed to assess the effectiveness of lavender essential oil therapy in the management of pain and anxiety after cesarean delivery. This was a monocentric randomized controlled double-blind trial conducted over a period of five months during 2023. A hundred women undergoing c-sections under spinal anesthesia were enrolled and randomly assigned; using block randomization of 4 items per block with allocation ratio 1:1, into two groups: The aromatherapy group (receiving inhaled Lavender essential oil) versus the placebo group (receiving distilled water instead). The primary outcomes were pain (at rest and after mobilization) and anxiety levels and after the intervention. This trial was registered on clinical-trials.org (NCT06387849). A total of 100 women were included (50 women in each group aromatherapy and the placebo group). The two groups were comparable regarding baseline characteristics and pre-intervention parameters with no statistically significant difference. After the intervention, the pain at rest (38,76 ± 22,9 vs. 23,84 ± 18,01; p < 0.001), the pain after mobilization (60,28 ± 23,72 vs. 40,12 ± 22,18; p < 0.001), and degree of anxiety (46,76 ± 6,59 vs. 44,3 ± 5,17; p = 0.03) were all significantly lower in the aromatherapy group. No adverse effects were reported by participants in both groups. Aromatherapy using Lavender essential oil is effective in reducing pain and anxiety after cesarean delivery without adverse effects.

Lavender essential oil market integrity: A comprehensive study of commercial Lavandula angustifolia essential oils adulteration and assessment of industrial standards

Adulteration of essential oils (EOs) is a common and unethical practice that affects both consumers and honest suppliers and harms market integrity. Despite the awareness of this problem, scarce scientific studies are described in the scientific literature. Therefore, 55 samples of lavender EOs were purchased and extensively analyzed to the trace levels, including chromatographic profile, quantitative analysis, and chiral profile. Of the 51 samples labeled as Lavandula angustifolia, 51 % were genuine, 6 % were cheaper lavandin EO, 14 % were fortified with synthetic additives and over 29 % of the samples were adulterated with both lavandin EO and synthetics. Usually, adulterated EOs were cheaper than genuine products, still some expensive products were also falsified. The most common synthetic adulterants were synthetic linalool and linalyl acetate, 3,5,5-trimethylhexyl acetate, α-terpinyl acetate, and dipropylene glycol. Only four of the studied samples were diluted with a medium not fully visible in the recorded GC profile. Industry standards were assessed to eliminate adulterated EOs and ISO 3515 was found to be impractical and too strict, but Ph. Eur. demonstrated its efficiency in eliminating adulterated samples without rejecting many genuine ones.PCA enabled the differentiation of lavender EOs containing synthetics from those of purely natural origin, and in the latter group, to distinguish L. angustifolia from lavandin. Some samples had an unusual composition suggesting that they were artificial blends of synthetics and some terpene fractions of non-lavender origin.This is the first such extensive study of adulteration of lavender EOs, regarding both the number of commercial samples as well as implications on their biological activity. The adulteration via dilution influenced the antimicrobial activity of the essential oils. In conclusion, adulteration is a significant problem in the market, and a large share of products on the market is somehow counterfeited, not only the cheapest products.

Application of Multivariate Data Analysis Methods for Rapid Detection and Quantification of Adulterants in Lavender Essential Oil Using Infrared Spectroscopy

Application of Multivariate Data Analysis Methods for Rapid Detection and Quantification of Adulterants in Lavender Essential Oil Using Infrared Spectroscopy

In vitro and Silico Exploration of the Insecticidal Properties of Lavandula multifida L. Essential Oil and its Binary Combinations with Cyantraniliprole and Emamectin benzoate on Spodoptera frugiperda (Lepidoptera: Noctuidae)

Control methods have faced challenges in effectively managing the spread and damage caused by the fall armyworm (FAW), Spodoptera frugiperda, across various crops worldwide, highlighting the need for more sustainable and integrated approaches. This study explored the insecticidal effect of the essential oil (EO) of lavender (LV) (Lavandula multifida L.), cyantraniliprole (CY), and emamectin benzoate (EM) insecticides on FAW larvae. Toxicity, biological, and biochemical assays were employed to elucidate the impact of the two insecticides individually or combined with LV EO. Additionally, in silico molecular docking investigations were performed for eucalyptol (the major component of LV EO) and for CY against the acetylcholine esterase (AChE) enzyme (PDB ID: 6xyu) and cytochrome P450 (PDB ID: 2q6n). EM was the most toxic compound to FAW larvae with an LC50 of 0.0073 mg L−1, followed by CY and LV EO. The chi-square (χ2) test confirmed the synergistic effect of the LV EO/CY combination and the antagonistic effect LV EO/EM combination on FAW larvae. Biological development studies revealed that both LV EO/CY and LV EO/EM combinations impacted the larval and pupal durations. The biochemical assays indicated that the P450-specific activity was activated by LV EO (at LC25), CY (at LC25 & LC50), and their binary combination (at LC25:LC25). In addition, the LV EO/CY combination significantly activated the AChE and GST-specific activity, and the LV EO/CY combination and CY (at LC50) significantly activated α-esterase- specific activity. Molecular docking investigations revealed energy scores (S) of −6.7729 and −7.7644 kcal/mol for eucalyptol and CY, compared to −7.0993 kcal/mol for PDB ID: 6xyu ligand. The current results can serve as baseline data for utilizing the LV EO/CY combination in the integrated pest management (IPM) of FAW.

Lavender improves sleep through olfactory perception and GABAergic neurons of the central amygdala

Ethnopharmacological relevanceThe use of lavender as sleep aid or hypnotic agent can be traced back as early as ancient Romans and Greeks. Yet, objective experimental data on whether and how lavender enhances sleep duration or/and sleep quality remain lacking. Aim of the studyWe aimed to characterize the sleep-wake regulating effects of lavender in the mouse and to demonstrate the brain targets and neural circuits involved. Materials and methodsA self-made precise odor delivery system combined with chronic polysomnographic recordings was employed to assess the sleep-wake effects of inhalation with lavender essential oil (LEO, extracted from lavender) and its different constituents during the light and dark phases in free-moving C57BL/6J mice. Neuroviral labeling, in situ hybridization and pharmacogenetics were combined to identify the neural circuits and targets involved. Finally, an insomniac model of DL-4-Chlorophenylalanine (PCPA)-treated mice was established to examine the sleep-inducing potential of LEO. ResultsWe found that inhalation of LEO with a concentration at 25.0% during the light (inactive) phase significantly shortened the latency to non-rapid eye movement (NREM) sleep, increased the total amount of NREM sleep at the expense of wakefulness (W), and enhanced cortical EEG slow wave activities, notably delta power spectra density. We further identified linalool, d-limonene, 1,8-cineole, linalyl acetate and terpinene-4-ol as the major effective sleep-promoting monomer components. Importantly, we found that LEO no longer produced any of the above sleep-promoting effect following either nasal injection of zinc sulfate which interrupts the olfactory pathway, or pharmacogenetics silencing of central amygdala GABAergic neurons. Finally, LEO reestablished NREM sleep with short latency in PCPA-treated insomniac mice, effects comparable with those induced by a potent sedative diazepam. ConclusionsWe have characterized the quantitative and qualitative sleep-promoting effects of LEO and its effective components via the olfactory pathway and central amygdala GABA neuronal targets. The hypnotic property of LEO is reinforced by its ability to restore sleep in insomnia. Our study thus establishes a neurobiological basis for aromatherapy of sleep disorders using lavender.

Effects of eggshell powder emulsion gel on the oxidative stability and sustained-release effect of lavender essential oil

This study aimed to develop a new type of eggshell powder (EP) emulsion gels for improving the antioxidant ability and sustained release effect of lavender essential oil (LEO). The effects of EP addition on the physicochemical, structural properties, oxidative stability, and sustained-release performance of the emulsion gels were investigated. The results showed that with the increase of EP addition (0–1 %), the gel strength initially increased and then decreased. The emulsion gel with 1 % EP had better freeze-thaw stability (36.77 %), thermal stability (78.63 °C), and water holding capacity (96.57 %). Moreover, the micromorphology results indicated that the EP-ovalbumin (OVA)-konjac glucomannan (KGM) complex showed a connected filamentous network structure, and the emulsion gel with 1 % EP addition had the most uniform and densest network structure. Furthermore, the EP emulsion gel had the highest free sulfhydryl content and hydrophobic interaction, and LEO exhibited the best antioxidant and sustained-release properties at this time. In conclusion, the findings demonstrated the potential of eggshell powder to enhance emulsion gel stability, which could improve the high-value utilization of egg by-products.

Meta-analysis of the Effect Size of Lavender Essential Oil and Lavender Blended Essential Oils on Psychological Factors in Adults

Purpose: This study analyzed the effect size of lavender essential oil and lavender blended essential oils on adult psychological factors. A meta-analysis was conducted to recommend an effective application strategy for improving psychological factors in adults.Methods: To analyze the effect size of lavender essential oil and lavender blended essential oils on psychological factors in adults, studies published over the last 10 years (January 2013 to December 2023) were collected. Studies were selected based on the population, intervention, comparison, outcomes, and study-format focusing on those that compared the pre and post psychological health of experimental group and control group and presented the mean and standard deviation. Data were analyzed using the version 4 software by Biostat (Englewood, USA).Results: Treatment with lavender essential oil alone showed highly positive effect on anxiety (0.731) and stress (0.730), followed by positive effects on sleep quality (0.673) and fatigue (0.601). Furthermore, treatment with lavender blended essential oils showed the most positive effects on sleep quality (1.383), followed by fatigue (1.159), stress (0.789), and anxiety (0.638).Conclusion: This study, discovered that lavender essential is effective in relieving anxiety and stress when used to improve adult psychological factors (anxiety, sleep quality, stress, and fatigue), and lavender blended essential oils are particularly effective in improving sleep quality and reducing fatigue. These results are expected to be valuable in prescribing treatments for individuals of various ages and lifestyles suffering from various psychological factors.

Fabrication and characterization of bioactive curdlan and sodium alginate films for enhancing the shelf life of Volvariella volvacea

This study aimed to develop bioactive films based on curdlan (CD) and sodium alginate (SA) to enhance the shelf life of the Volvariella volvacea mushroom. A stable nanoemulsion of droplet size of 150.1 ± 5 nm was first formulated using 5% soy protein (Sp) and 10% lavender essential oil (LEO), achieved by ultrasound treatment for 10 min, resulting in small droplet sizes. In parallel, a CD-SA film was prepared by mixing them in a 1:1 ratio. The SpLEO nanoemulsion was then ex situ added to the CD-SA film at varying concentrations (4%, 6%, 8%, and 10%). The resulting bioactive film exhibited desirable properties, including water vapor permeability (1.15 ± 0.05 × 10−10 g m−1 Pa−1 s−1), swelling rate (547%), and tensile strength (10.1 ± 1.3 MPa). Docking and structural analyses suggested that ultrasound treatment enhanced the intermolecular hydrogen bonding, creating a uniform and regular surface and reduced crystallinity. The CD-SA film with ultrasound-treated 8% SpLEO nanoemulsion [i.e., (CD-SA/SpLEO-8)US] showed antibacterial activity against Escherichia coli and Staphylococcus aureus and extended the freshness of straw mushrooms prevention of spoilage during storage. Additionally, the film reduced respiration rate (975 mg CO₂/kg/h at 96 h) and ethylene production (160 ng/kg/s by 96 h) while effectively inhibiting straw mushroom autolysis. This led to a reduction in browning (2.91), total soluble solids (7.5%), weight loss (13.9%), and polyphenol oxidase activity (0.08 ΔOD420/min⋅g), thereby extending the shelf life of the mushrooms to 96 h. These findings highlight the potential of incorporating different molecules using ultrasound treatment to develop innovative edible films for food preservation.

Sustainable antimicrobial functionalization of cotton with lavender oil and jackfruit latex

In recent years, functional antimicrobial fabric materials have been in high demand in the health sector due to the impact of COVID-19. Considering the increasing demand, the availability of natural, environmentally friendly, and non-toxic products is limited. In this study, a facile, eco-friendly method for the preparation of antimicrobial functional cotton fabric is proposed. At first, scoured and bleached cotton fabric is treated with chitosan, followed by encapsulation of lavender essential oil (LEO) with the addition of Artocarpus heterophyllus Lam. (jackfruit) latex gum as a binder. For the encapsulation and optimization of LEO and jackfruit latex gum (JLG) performance, four variations of these material’s quantity were utilized. Among all the studied samples, we found that the most efficient inhibition of bacterial growth was induced in both gram-negative (Escherichia coli) and gram-positive (Staphylococcus aureus) cultures. Among the samples, the chitosan-treated fabric with LEO and JLG added, named TG-5 (refers to LEO of 3 mL and JLG of 5 mL), showed the most impactful bacteria reduction. It demonstrates the most effective antibacterial reduction of 92.5% and 56.8% for E. coli and S. aureus bacterium cultures, respectively. The field emission scanning electron microscope illustrates and validates the morphology and addition of the prepared samples, while Fourier transform infrared is employed to identify the chemical bonding and chemical compounds of the functionalized materials. Therefore, the new combination of lavender oil and latex gum of jackfruit as an antimicrobial finishing agent can be the replacement of synthetic chemicals for cotton fabric functionalization in medical textiles.

Development and Evaluation of Oromucosal Spray Formulation Containing Plant-Derived Compounds for the Treatment of Infectious and Inflammatory Diseases of the Oral Cavity.

According to data in the literature, natural products and essential oils are often used in dental practice. To develop a new oromucosal spray for the treatment of infectious and inflammatory diseases of the oral cavity, clove CO2 extract and essential oils of lavender and grapefruit were used as active pharmaceutical ingredients. Clove extract was obtained by the method of subcritical extraction from various raw materials, the choice of which was based on the yield of the CO2 extract and the study of its phytochemical and microbiological properties. Based on the results of microscopic and diffraction analyses, the rational time of ultrasonic exposure for the emulsion of active pharmaceutical ingredients was established. Mucoadhesive polymers were used as stabilizers of the two-phase system and prolongators. This article discusses the impact of the type and concentration of mucoadhesive polymers on the stability of the emulsion system; the viscous, textural, adhesive, and film characteristics of oromucosal spray; and the parameters determining sprayability.

Sustained-release effect of eggshell powder microcapsules on lavender essential oil

Eggshells are rich in Ca2+ and organic compounds, which can be taken as coupling agents for sustained-release materials. Essential oils are widely applied due to their excellent volatility, but poor sustained-release stability has limited their development. The study aimed to develop a novel eggshell powder (EP) sustained-release microcapsule, providing a new approach to protect the active ingredients of Lavender essential oil (LEO), and investigated the reasons for EP to regulate protein-polysaccharide microcapsule structure. Experimental results showed when the addition ratio of EP and Whey protein (WPI) was 1: 3, the dosage of LEO was 25%, the microcapsule displayed smooth and porous spherical structure. XRD and FT-IR indicated that a dense and orderly network structure was formed via the cross-linking reaction between eggshell powder and wall materials, which induced protein and polysaccharide to form special spherical hollow sustained-release shell structure through the calcium bridge (-COO-Ca-COO-), then achieved the sustained-release effect on LEO.

Evaluation of lavender essential oils and by-products using microwave hydrodistillation and conventional hydrodistillation

This study investigated the impact of two extraction methods, traditional hydrodistillation (TDH) and microwave-assisted hydrodistillation (MAH), on the essential oil yield and chemical profile of Lavandula angustifolia L., as well as the bioactive potential of the resulting wastewater. Essential oil composition was analyzed via GC–MS, revealing similar qualitative and quantitative profiles for both methods, with α-terpinolene and (–)borneol as major constituents. Wastewater analysis via LC–MS/MS and spectrophotometric assays demonstrated the presence of significant total phenolic content (3.29–1.78 mg GAE/g) and 32 individual phenolics (463.1 µg/kg for TDH; 479.33 µg/kg for MAH). These findings suggest that both essential oil and wastewater obtained by either method possess considerable bioactive potential, with the MAH method potentially offering advantages over TDH for essential oil extraction. Further exploration of wastewater applications in various industrial sectors is warranted.

The Role of Essential Oils on Sleep Quality and Other Sleep-related Issues: Evidence from Clinical Trials.

Essential oils (EOs) are a volatile mixture of bioactive compounds extracted from aromatic plants. The composition of EOs varies, which majorly depends on the extraction methods and plant parts. Aromatherapy using EOs has been reported for its several beneficial effects in humans. Aromatherapy is considered a complementary and/ or adjuvant therapeutic approach for treating several illnesses, especially to improve mental health and well-being. The incidence of sleep disorders, specifically insomnia, is nowadays increased, possibly due to urbanization and lifestyle. The studies showed that EOs-based treatments using lavender EO, bergamot EO, cinnamon EO, and rosemary EO (alone or in combinations) could improve sleep quality, duration, and deprivation in healthy subjects and patients, those who suffer from sleep-related issues. The current manuscript details the outcomes of EO-based treatments on the sleep quality of humans and the possible mechanisms associated with the health-promoting properties of EOs. Also, the toxicity and adverse effects of EOs have been discussed. The study indicated that EOs are potent adjuvant therapeutic candidates to manage mood-associated complications in humans. Moreover, the aromatherapeutic field requires detailed studies on toxicity and dose determination, which could provide safe and effective therapeutic results.

Beta-Myrcene as a Sedative-Hypnotic Component from Lavender Essential Oil in DL-4-Chlorophenylalanine-Induced-Insomnia Mice.

With the increasing prevalence of insomnia-related diseases, the effective treatment of insomnia has become an important health research topic. Lavender (Lavandula angustifolia Mill.) essential oil (LEO) is a commonly used medicine for the treatment of insomnia and neurological disorders. However, neither the active components nor its sedative-hypnotic mechanism have been fully discovered. This study aimed to screen the main active terpenes and discover the possible mechanism of LEO through network pharmacology in the treatment of insomnia-related diseases, as well as to verify our hypothesis in insomnia mice. The results showed that, in LEO's 15 potential active ingredients, beta-myrcene had strong sedative-hypnotic effects through the serotonergic synaptic pathway according to the network pharmacological prediction. Further, PCPA(DL-4-chlorophenylalanine)-induced insomnia mice were treated with beta-myrcene for one day or seven days. The quiet state of insomnia mice was increased effectively, and the hypnotic effect was enhanced by anaobarbital sodium by prolonging sleep duration, decreasing sleep latency, and increasing the rate of falling asleep. Beta-myrcene reduced the damage to hypothalamic neuron cells induced by PCPA and increased neurotransmitter levels of GABA, 5-HT, and Glu in the serum and hypothalamus of insomnia mice. Meanwhile, beta-myrcene exerted an improvement in insomnia by upregulating relevant genes and protein expression in the serotonergic synaptic pathway. These results support the merit of the sedative-hypnotic activity of LEO. Beta-myrcene, a terpene in LEO, may be the main source of its sedative-hypnotic properties. It may serve as a good potential compound in future clinical studies on coping with insomnia.

Tiny pills, big impacts: A systematic review on the endocrine disrupting effects of paediatric pharmaceuticals

Endocrine disrupting chemicals (EDCs) may impact children's health, with medicines as a possible exposure source. Objective: to assess the potential impact of substances in paediatric medications and essential oils on children as EDC. It is a systematic review of five databases including Medline following the PECOT approach. The review focused on publications about children exposed to medication (active ingredients or excipients of interest) and having developed clinical signs of endocrine dysfunction. Out of 946 studies identified, 28 studies were included. They revealed that parabens, lavender essential oils and anti-epileptics are the most identified pharmaceutical products. The reported outcomes relate to puberty, thyroid disorders, obesity and growth. The evidence indicates potential risks, but the overall quality of available data is limited. This systematic review exposes a lack of robust evidence linking paediatric medication exposure to EDC, predominantly relying on case reports. It cautions about potential conflicts of interest.

AROMA THERAPY INTERVENTION TO IMPROVING SLEEP QUALITY IN PATIENTS WITH CARDIOVASCULAR PROBLEMS

Background: Poor sleep quality will lead to stressful conditions which can cause the release of epinephrine and norepinephrine has the effect of increasing the oxygen demand for the myocardium. Aromatherapy is recommended as a no-side-effect, non-invasive, inexpensive and painless method to reduce anxiety and pain. improve sleep quality of cardiovascular patients. Purpose: The aim of this study is to analyze the potential of aromatherapy interventions in patients with cardiovascular disorders. Methods: The research method in this article uses a literature study approach. The articles will be selected based on the following criteria. The search sources in this article use scientific-based databases (ScienceDirect, PubMed, EBSCOhost, and Wiley Library Online). The search starts from December 2022 using the keywords Cardiac Patients – Aromatherapy – Sleep quality. Result: Inhalation aromatherapy with peppermint or lavender essential oil can improve the sleep quality of cardiovascular patients. Inhaling aromatic oil stimulates the sense of smell affecting the central nervous system. Lavender oil can reduce fatigue, anxiety, heart rate, respiratory rate, and blood pressure, improve lung and brain oxygenation, and improve sleep quality. The use of essential oils can be a safe and cost-effective therapy for sleep disorders and can reduce the overuse of prescription medications. Implication: Lavender and peppermint essential oils have a therapeutic effect that relaxes the body. These effects can make the body feel relaxed and release hormones that can help patients sleep. However, this intervention still needs further research specifically from the aspect of dose and medium of aromatherapy.