Maxcy (1926) first noted that rats and mice might be the reservoir of endemic typhus, and that fleas, mites, or ticks, were probable transmitters of the disease in the United States. Since that time, many investigators have recovered the rickettsiae of typhus fever from rats and their fleas. Dyar, Rumreich, and Badger (1931) first demonstrated the natural infection of the rat fleas, Xenopsylla cheopis (Rothschild) and Leptopsylla segnis (Schonheer) with endemic typhus. The fleas were taken from rats trapped in Baltimore, Md., and Savannah, Ga. Brigham (1941) reported the recovery of endemic typhus fever rickettsiae from naturally infected chicken fleas. Alicata (1942) obtained experimental transmission of the typhus rickettsiae from rat to rat with the sticktight flea, Echidnophaga gallinacean (Westwood). Dove and Shelmire (1932) reported the laboratory transmission of endemic typhus from guinea pig to guinea pig through the bites of tropical rat mites, Liponyssus bacoti (Hirst). Mooser, Zinsner, and Castaneda, working in Mexico City in 1930, obtained transmission from rat to rat by the rat louse, Polyplax spinulosa (Burmeister).