Sodium Dodecyl Sulfate Research Articles

Sequential separation of anti-diabetic drugs in the presence of melamine as impurity using chromatographic methods

The study of green analytical chemistry has garnered significant attention in the context of mitigating global environmental contamination. In this study, we present two methodologies for environmentally friendly chromatography that enable simultaneous and specific determination of Saxagliptin (SAX), metformin (MET), and a pharmacopoeial impurity of MET known as melamine (MEL). The initial method employed in this study is High-Performance Thin Layer Chromatography (HPTLC), which utilized 60 F 254 silica gel-coated Mark HPTLC plates on aluminum sheets as the stationary phase. The developing system was made up of a mix of ethyl acetate: methanol: ammonia: glacial acetic acid in a ratio of 6:4:1:0.3 (v/v/v/v). The analysis was performed at a wavelength of 215 nm. The second method employed in this study is ultra-performance liquid chromatography (UPLC). In this method, a C18 column was utilized for the separation process. The mobile phase was made up of a mix of methanol and 0.01 M sodium dodecyl sulfate, with a pH of 3.3 achieved by adding orthophosphoric acid. The ratio of methanol to sodium dodecyl sulfate in the mobile phase was 70:30 (v/v). The flow rate of the mobile phase was established at a rate of 1.5 mL/min. The peaks found and recorded are resolved at a wavelength of 215 nm. The three analytes under investigation were successfully separated and assessed using the recommended protocols. Both methods were validated following the International Council for Harmonization (ICH) recommendations for assessing linearity, range, accuracy, precision, specificity, and robustness. Moreover, the environmental sustainability of the advanced methodologies The assessment has been performed using various instruments, such as the Analytical Eco-Scale, NEMI, GAPI, and AGREE. The utilization of these tools was implemented in order to perform a comprehensive assessment of the environmental sustainability of the methods, as well as to establish a comparison with previously documented approaches. This study was carried out to evaluate the potential environmental implications of the suggested methods and to determine their suitability for concurrent analysis of the examined pharmaceuticals in formula and quality control units.

The impact of different cooking temperatures on the quality and moisture distribution of beef.

The objective of this study was to investigate the water-holding capacity (WHC) and quality changes of beef during heating at specific temperatures (including 40 °C, 60 °C, 80 °C, and 100 °C), as well as the degradation of proteins and the distribution of water within the muscle at different heating temperatures. The experiment utilized the sirloin section from eight crossbred cattle of Luxi Yellow Cattle and Simmental breeds, with four sampling sessions, two cattle per session. Each cattle were divided into 30 beef sirloin samples, each weighing 150 ± 10 g, and each session was completed within 3 days with the following tests. Measurements included cooking loss and dimensional shrinkage, as well as quality indicators such as pH value, meat color (L*, a*, b*, and ΔE values representing lightness, red-green chroma, yellow-blue chroma, and color difference, respectively), and texture. Sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) and low-field nuclear resonance (LF-NMR) techniques were employed to assess protein degradation and water distribution in the beef. The results indicated that the increase in cooking loss and dimensional changes during heating may be associated with a reduction in nonflowing water. Moreover, the temperature range of 60°C to 80 °C is critical for these changes; within this range, myoglobin begins to degrade, and the values of L*, a*, b* as well as ΔE reach their peaks, thereby enhancing the chewiness and elasticity of the beef. Therefore, the changes in beef quality and water distribution at different temperatures are influenced by three states: the degree of muscle fiber contraction, the state of protein degradation, and the capacity for water migration. This finding provides a theoretical basis for improving beef processing quality and refining meat production processes.

Comparing Genomic DNA Extraction Methods/ Protocols to obtain High Quality DNA from Ulva lactuca

DNA extraction is the process of isolating the nucleic acid (e.g. DNA) from the cells isolated from organism or samples. DNA extraction protocol is crucial for the quality of DNA to be isolated from a sample, it also entails the success of other downstream application like PCR amplification and sequencing. In this study, three (3) extraction protocols were used to extract DNA from the blade of a seaweed, the Ulva lactuca. The protocols that were used in this study were optimized to extract genomic DNA for other organisms, for instance, the sodium dodecyl sulfate (SDS) method was used for insects, the tri-phosphate extraction (TPE) method is used for rice, while cetyltrimethylammonium bromide (CTAB) method is commonly used for plants. Some of the components of the protocols were modified like for instance changing the pH of Tris-HCl. The experiment consists of two trials with two replicates in each trial, the trials ensure the reliability of result, specifically the experiment. For the first trial, the TPE method got the highest DNA concentration of 304.1 ng/ul but it did not pass the purity ratio of A260/280 (1.8-2.0) by only having 1.46, however, two replicates pass the A260/280 ratio and both are the replicates 1 of SDS and CTAB protocol having 1.81 and 1.80 A260/280 ratio and the concentrations of 127 ng/ul and 77.0 ng/ul, respectively. For the second trial, both the replicates using CTAB protocol pass the A260/280 ratio with 1.82 and 1.81, and DNA concentration of 24.2 ng/ul and 1,993.6 ng/ul, respectively. This concludes that, still the conventional genomic DNA extraction protocol for plants, which is the CTAB method can also be used to isolate high quality DNA from a green seaweed, the Ulva lactuca. However, some of the components of CTAB method poses health risks and possible environment hazard, the TPE and SDS method can offer a less harmful way to extract DNA, though further optimization on the components of the two protocol is highly encouraged. This study also shows that CTAB can also be used to isolate DNA from other marine plants.

Photocatalysis by Mixed Oxides Containing Niobium, Vanadium, Silica, or Tin

Nb-Sn, V-Sn mixed-metal oxides and Nb-Si, V-Si metal oxide–silicas were successfully synthesized through a “soft” templating method, in which appropriate amounts of metal salts (either niobium(V) chloride, or vanadium(IV) oxide sulfate hydrate or tin(II) chloride dihydrate) or tetraethyl orthosilicate (TEOS) were mixed with hexadecyltrimethylammonium chloride (HDTA) or sodium dodecyl sulfate (SDS) solutions to obtain a new series of mesoporous oxides, followed by calcination at different temperatures. As-obtained samples were characterized by SEM, TEM, XRD, and UV-Vis spectra techniques. The photocatalytic activities of the samples were evaluated by degradation of methyl orange II (MO) under simulated sunlight irradiation. The effects of metal species and calcination temperature on the physicochemical characteristic and photocatalytic activity of the samples were investigated in detail. The results indicated that, compared to pure oxides, mixed-metal oxide showed superior photocatalytic performance for the degradation of MO. A maximum photocatalytic discoloration rate of 97.3% (with MO initial concentration of 0.6·10−4 mol/dm3) was achieved in 300 min with the NbSiOx material, which was much higher than that of Degussa P25 under the same conditions. Additionally, the samples were tested in the photochemical oxidation process, i.e., advanced oxidation processes (AOPs) to treat the commercial non-ionic surfactant: propylene oxide ethylene oxide polymer mono(nonylphenyl) ether (N8P7, PCC Rokita). A maximum of 99.9% photochemical degradation was achieved in 30 min with the NbSiOx material.

Hierarchical Porous PbO2 Electrode for Electro‐Degradation of Various Contaminants

Persistent organic contaminants in water pose imminent threats to aquatic ecosystems and human health, yet conventional water treatment systems are not able to remove them effectively. Electrochemical oxidation is a promising treatment alternative for the mineralization of persistent organic compounds. Herein, a novel hierarchical porous PbO2 electrode is fabricated via direct electrodeposition on a templated fluorine‐doped tin oxide surface. Physical and electrochemical characterization confirm the superior properties (e.g., enhanced electrochemical active surface areas) of the produced electrode. In addition, compared with macroporous PbO2 and PbO2 electrode films, the hierarchical porous PbO2 electrode shows significantly improved degradation performance against a variety of pollutants, including sodium dodecyl sulfate, rhodamine B, and sodium diclofenac. Overall, it is demonstrated that the hierarchical porous PbO2 electrode can be utilized for efficient electrochemical oxidation of organic contaminants.

Catanionic synergetic effect of sodium dodecyl sulphate and cetyl trimethyl ammonium bromide surfactants on the electrochemical performance of porous carbon anodes in lithium-ion batteries

Catanionic synergetic effect of sodium dodecyl sulphate and cetyl trimethyl ammonium bromide surfactants on the electrochemical performance of porous carbon anodes in lithium-ion batteries

The Effect of Sodium Dodecyl Sulphate Additives on the Electrochemical Performance of Aqueous Zinc Ion Batteries

Aqueous zinc ion batteries are considered one of the most promising energy storage devices due to their high safety, low cost, and ease of fabrication. However, the growth of anode dendrites and continuous side reactions during cycling limit the practical application of zinc ion batteries. In this paper, sodium dodecyl sulfate (SDS) was used as an aqueous electrolyte additive to improve the surface deposition of Zn2+. The experimental results show that the SDS electrolyte additive forms a protective layer on the anode surface through electrostatic action and inhibits the growth of dendritic protruding dendrites by increasing the zinc deposition overpotential, as well as by limiting the two-dimensional diffusion of Zn2+ on the negative electrode surface of the aqueous zinc ion battery. As a result, adding SDS improves the discharge specific capacity of NVP/Zn batteries at high voltages and results in improved capacity retention. The cycling stability of NVP/Zn batteries was greatly enhanced by using a battery containing 1% SDS that still had a discharge specific capacity of 71 mAh/g after 100 cycles at a charging current density of 1 C, with a capacity retention rate of 89%. This work provides a simple and feasible solution to the anode problem of aqueous zinc ion batteries.

Pyridinium surfactants can modulate the UV response of methyl green dye‐doped polymeric films for sensor development

AbstractConcerns about ultraviolet radiation (UV‐R) are increasing due to climate change. The effects of UV‐R on living organisms depend on exposure duration and intensity, making it crucial to monitor UV‐R levels. In this study, we investigated the role of surfactants as photosensitizing or stabilizing agents in a colorimetric sensor based on a polymeric film doped with methyl green dye. The films were synthesized using the casting technique from a filmogenic solution containing either carboxylated polyvinyl alcohol (P1) or hydroxylated polyvinyl alcohol (P2). We evaluated the impact of surfactant structure (dodecylpyridinium chloride, C12; hexadecylpyridinium chloride, C16; or sodium dodecyl sulfate, SDS) and concentration on the colorimetric response of the films to UV‐R. Color changes were monitored using the CIELab system. The results showed that, under UV‐R exposure for up to 5 h, films without surfactants did not lose their blue hue (negative b* parameter in CIELab). While SDS stabilized the dye in the polymeric matrix, films containing pyridinium surfactants (C12 or C16) changed color from blue to pale yellow (positive b* parameter in CIELab). The color change, which was modulated by surfactant concentration, was attributed to radical reactions involving the pyridinium surfactants, influenced by their hydrophobicity and the polymer structure. These results represent a significant advancement in colorimetric sensors for UV‐R, as they allow for the modulation of the sensor's response time through surfactant concentration in the polymeric film.

Effects of a New Enzymatic Debrider (SN514-066b) on Eschar Protein Digestion, Burn Wound Debridement, and Healthy Skin Irritation.

Objective: SN514 is a thermolysin-like enzyme under development as a debrider. Preclinical and non-clinical studies supported a first in human healthy volunteer study to predict the need for protection of periwound skin. Approach: Pharmacologic activity testing compared in vitro digestion of collagen, fibrin, and elastin with relevant enzymes. A Yorkshire pig model of burn injury was used to evaluate debridement over 10 days and effects on intact skin. A human 21-day cumulative irritation study using Webril patches taped to the backs of 38 healthy adult volunteers compared four enzyme concentrations (0.10%, 0.20%, 0.40%, and 0.80% w/w) with the hydrogel vehicle, saline (low irritant control), and 0.2% sodium lauryl sulfate (positive irritant control) using randomized placements and blinded evaluation. Results: SN514 showed excellent digestion of fibrin, elastin, and collagen in vitro. Burn wound studies in Yorkshire pigs showed efficient eschar debridement with minimal periwound erythema. Direct treatment on intact porcine skin for 5 days produced no to limited erythema. The preclinical findings of minimal irritation with SN514 were verified by a Phase 1 first-in-human 21-day cumulative skin irritation test. Irritation was observed to increase stepwise by concentration, confirming formulation accuracy. Each enzyme concentration was found to be "possibly mild in use" (Berger and Bowman method). No treatment emergent adverse events were observed during the study. Innovation: A fast-acting enzyme with a favorable irritation profile, prepared as a stable, ready to use hydrogel formulation, overcomes many recognized shortcomings of enzyme debriders. Conclusion: The overall findings support clinical dose range testing for tolerance and preliminary efficacy.

Primary Recovery of Carboxymethyl Cellulase from Thermophilic Bacillus licheniformis 2D55 Using an Aqueous Two-phase System

This study uses an aqueous two-phase system developed from a polymer and salt to purify a thermostable carboxymethyl cellulase (CMCase) produced by thermophilic Bacillus licheniformis 2D55. The effects of system parameters, such as polyethene glycol (PEG) molar mass, salt concentration, crude load, NaCl concentration and pH on partitioning and recovery efficiency, are evaluated. Sodium dodecyl sulphate polyacrylamide gel electrophoresis (SDS-PAGE) is used to determine the purity of the CMCase. The enzyme is successfully purified, achieving a 10.9-fold purification and 86.62% yield. The maximum purification condition is achieved in ATPS comprising 20.5% PEG 8000/15% sodium citrate, with a crude load of 17% (w/w), NaCl of 1.0% (w/w) and pH at 7.0. Under these conditions, a partition co-efficient of 0.21 is observed, indicating that CMCase preferentially partitions to the bottom phase. These results demonstrate the potential of ATPS for the purification of thermostable CMCase from the fermentation broth of thermophilic Bacillus licheniformis 2D55.

Changes in fetal hemoglobin levels in patients with liver cirrhosis with type 2 hepatorenal syndrome and chronic kidney disease

Liver cirrhosis (LC) is highly prevalent in the modern population and is the leading cause of death among all gastrointestinal tract diseases. The course of cirrhosis can be aggravated by a number of conditions that makes the management of patients with this pathology even more challenging. One of these conditions is hepatorenal syndrome (HRS) type 2. This condition is a special form of chronic kidney disease (CKD), in which it is believed that changes in the kidneys are largely functional and reversible. Diagnosis and treatment of HRS type 2 in LC require special approaches.The purpose of the study. To establish possible differences in fetal hemoglobin (HbF) indicators in patients with structural damage to kidney tissue in CKD and renal dysfunction associated with the development of type 2 HRS in patients with LC.Materials and methods. Participants were recruited among patients of the therapeutic and gastroenterological departments of the State Healthcare Institution of the Astrakhan Regional Clinical Hospital in Astrakhan. The study included 40 patients with Child-Pugh B, C LC without signs of HRS, 21 with LC and HRS type 2, 92 with CKD of stages 3, 4, 5, and 43 healthy donors in the control group (CG). HbF analysis was performed by rocket electrophoresis in agar gel with sodium dodecyl sulfate using pure HbF preparations and the author's monospecific antisera to Hb F. Results. To identify additional criteria for the differential diagnosis of HRS type 2 and CKD, a study of the HbF level was conducted in these groups of patients, as well as their comparison by this indicator LC without HRS and CG. The study revealed a statistically significant decrease in HbF in the CKD group compared to patients with LC with type 2 HRS, LC without HRS, and GC.Conclusion. The identified changes allow using quantitative determination of the HbF level for differential diagnostics of organic kidney damage, characteristic of CKD, from renal dysfunction in type 2 HRS in patients with cirrhosis. The presence of CKD in a patient is indicated by a reliable decrease in HbF parameters, compared with the norm, while in cirrhosis with type 2 HRS they exceed normal values.

Porous Hydrogels from Nanoemulsion Templates With Different Structures

AbstractPorous hydrogels, including physical pores and spaces within the polymer network, exhibit rapid water uptake rates. Synthesizing porous hydrogels through nanoemulsion templating represents a promising avenue for the development of advanced materials with tailored properties. Certain attributes, including but not limited to the ability to tune droplet size, volume fraction, and interdroplet interactions, provide tools to precisely manipulate the structure of nanoemulsions. The main research question is how the colloidal structure of the template changes the characteristics of a polymer network. Therefore, this study investigates the preparation of porous hydrogels using concentrated nanoemulsions as templates where modulating interdroplet interactions results in different pore structures and properties of the polymer network. Nanoemulsions are prepared by dispersing oil droplets in a continuous phase containing poly (ethylene glycol)‐diacrylate (PEGDA) and sodium dodecyl sulfate (SDS). Subsequent photo‐polymerization of PEGDA and removal of the oil phase leaves behind a porous polymer structure. Then, Hydrogels are analyzed to study the relationship between netwrok structures and water uptake capacities. The discussion focuses on how droplet arrangement under the influence of altered concentrations of SDS, provides confinement for changing the crosslink density of the polymer network.

Optimised Synthesis of Rhombic dodecahedral Cu2O Nanoparticles: A Pathway to Superior Morphological Control

AbstractCuprous oxide (Cu2O) nanoparticles hold significant promise for photocatalytic applications due to their narrow bandgap and high surface reactivity. This study focuses on the synthesis of rhombic dodecahedral Cu2O (RD‐Cu2O) nanoparticles, totally enclosed by {110} facets, known to exhibit superior photocatalytic performance over the other low‐index crystallographic facets. The precise control over the synthesis conditions can significantly enhance the exposure of this highly active face and therefore improve the catalytic performance of Cu2O nanoparticles, making them superior for applications in pollutant degradation, organic reactions, and artificial photosynthesis. We systematically optimised the synthesis parameters, including reactants concentration, pH and other reaction conditions, to achieve a significant scale up of well‐defined RD‐ Cu2O nanoparticles production, strictly necessary for the use of this photocatalyst on a larger scale. The optimised and scaled up synthesis require 2.0 mmol of CuCl2, 6.0 mmol of Sodium dodecyl sulphate (SDS), 9.6 mmol of NH2OH ⋅ HCl and 7.0 mmol of NaOH added in this order to 400 ml of water at 25 °C. The optimised nanoparticles demonstrated a narrow size distribution and a high degree of crystallographic control. Characterisation techniques such as FESEM, XRD, EPR, UV‐Vis spectroscopy, and XPS confirmed the improved morphological and structural properties of the synthesised RD‐Cu2O nanoparticles.

A comparative analysis of alpha olefin sulfonate and dodecyl sulfate in aphronic fluid containing xanthan gum in a wide range of temperatures

Geothermal energy, oil industry, and underground gas storage technology require deep drilling. Although oil-based drilling fluids have been widely used, they cause environmental issues. Environmentally friendly Aphronic fluid has emerged as an alternative to oil-based drilling fluid. Despite various investigations on Aphron’s performance, the effect of temperature has not yet been comprehensively studied. In this study, Aphronic fluid was developed with xanthan gum (XG) as a polymer and alpha-olefin sulfonate (AOS) as a surfactant. Furthermore, another Aphronic fluid was developed with xanthan gum (XG) as a polymer and sodium dodecyl sulfate (SDS) as a surfactant. This study evaluates their rheological properties, including shear rate (ranging from 0.1 to 10 s− 1), across a range of temperatures (25 ℃, 49 ℃, 71 ℃, and 93 ℃). Stability testing was conducted at ambient temperature, and rheology tests were performed at various temperatures. It was found that the rheological properties decrease as the temperature increases. An increase in the temperature and shear rate decreases the viscosity of the drilling fluid. AOS demonstrated higher stability and less reduction in rheological properties at elevated temperatures than SDS. This difference can be attributed to SDS’s tendency to denature the XG polymer, leading to a notable decrease in viscosity. Maintaining viscosity is crucial for fluid stability and enhancement of rheological properties. Moreover, the best stability was achieved at 1.5 times the critical micelle concentration (CMC). This behavior is consistent with the Gibbs elasticity theory, indicating that the optimal concentration for both AOS and SDS surfactants is 1.5 times the CMC. Deviation from this optimal concentration resulted in decreased system stability. The determination of the CMC value showed a broader region rather than a singular point, potentially confirming the Gibbs-Marangoni theory. The implications of this research underscore the importance of selecting the appropriate Aphronic fluid formula for drilling operations to ensure stability and rheological properties conducive to overcoming reservoir pressure and accurately facilitating the cutting transfer process. This research highlights the need to choose the right Aphronic fluid formula for drilling. Using the right formula helps in drilling to ensure stability and rheological properties conducive to overcoming reservoir pressure and accurately facilitating the cutting transfer process.

Optical Insight: Spectrophotometry as a Tool to Quantify Cell Density of Green Microalgae in Suspension, with Emphasis on Growing Conditions and Toxicological Evaluations.

Microalgae are often used in different industrial sectors and can be used as indicators of aquatic environmental health. An essential step for cultivating microalgae is assessing the cell density, which is traditionally performed through cell counting by optical microscopy (OM). However, this method has limitations, mainly in terms of runtime and low reproducibility. Assessing the optical density (OD) by spectrophotometry was investigated as an affordable alternative. The OD of the green microalgae Desmodesmus subspicatus and Tetraselmis sp. was detected at 680nm. The correlation between the cell density and OD was suitable for both microalgae and the accuracy was comparable to traditional OM counting. In toxicological tests, the OD technique allowed the monitoring of microalgal growth in the presence of the chemicals K2Cr2O7, KCl and sodium dodecyl sulfate. This study sheds some light on this well-known technique, which is an important contribution since few articles have explored its potentialities and fragilities.

Influence of goethite on the fate of antibiotic (tetracycline) in the aqueous environment: Effect of cationic and anionic surfactants.

Over the last decades, the release and occurrence of organic pollutants in aquatic systems have become a major global concern due to their bioaccumulation, toxicity, and adverse effects on the ecosystem. Tetracycline (TC), a widely used antibiotic, is often found at high concentrations in the aqueous environment and tends to bind with the natural colloids. Post-COVID-19 pandemic, the release of surfactants in the environment has increased due to the excessive use of washing and cleaning products. This study systematically investigated the interaction of goethite with TC in the absence and presence of anionic (sodium dodecyl sulfate, SDS) and cationic (cetyltrimethylammonium bromide, CTAB) surfactants. The impact of various environmental parameters like pH, ionic strength, temperature, and organic matter was also studied. It was observed that SDS has drastically increased TC sorption onto goethite from 11mg/g to 19mg/g, while CTAB had the opposite effect. To delineate the goethite-TC interaction mechanisms, FTIR with two-dimensional correlation analysis (2D-COS) was performed. The pH of the solution was crucial in the presence of SDS, while ionic strength did not affect the interaction process. The sorption process was endothermic, as evidenced by the increase in sorption capacity with the rise in the temperature. The presence of organic matter hinders the sorption of TC onto goethite, which is also observed in river water where the organic content is very high. Overall, our study helps to predict the fate of organic pollutants like antibiotics in aqueous environments in the coexistence of surfactants and iron oxyhydroxides.

Trivalent chromium ion removal from synthetic wastewater using graphene oxide nanocollector by various flotation mechanisms

ABSTRACT The scarcity of freshwater resources for industrial applications poses a significant global concern. Therefore, wastewater treatment is vital for industrial reuse and decreases environmental damage. Chromium, commonly encountered in industrial wastewater, is regarded as a highly toxic metal and a significant environmental pollutant. In this study, the ion removal of trivalent chromium was investigated by graphene oxide (GO) and sodium dodecyl sulfate (SDS) as collectors using various flotation methods including foam fractionation, ion flotation, and precipitation flotation. The effective parameters of the collector type and pH were studied to assess the chromium ion removal, water recovery during the process, and flotation mechanisms. Experimental results indicated that the highest ion removals, achieved with SDS and GO collectors, were 88.86% and 86.07%, respectively, at a pH of 6.3 using the ion flotation method. Notably, GO reduced water recovery by approximately 15% compared to optimal conditions using SDS. The results indicated the remarkably high efficacy of GO as a nanocollector in the ion flotation process for efficiently removing chromium ions with significantly lower collector consumption.

Preparation and characterization study of composite dust suppressant based on xanthan gum

To address the critical issue of particulate matter emitted from mining operations, which poses a significant risk to human health, production safety, and the environment, a novel dust suppressant based on xanthan gum (XTG) as a coalescing agent was introduced in this study. The formulation innovatively combines anionic surfactants SDS (Sodium dodecyl sulfate) and SDBS (Sodium dodecyl benzene sulfonate) as well as nonionic surfactants OP-10, Tween-20 (Polyoxyethylene anhydrous sorbitan monolaurate) and Tween-80 (Polyoxyethylene anhydrous sorbitan monooleate) with 0.05% XTG to enhance the wettability of the solution. Considering the economy and practicality, 0.05% OP-10 + 0.05% XTG (M-OX) was finally selected as the optimal dust suppressant formulation. Through a series of experiments, including surface tension, contact angle, sedimentation, pH value, water retention, and wind erosion resistance tests, we proved that M-OX, with a pH value of 8.03, has the least impact on the environment, has better water retention, and has a significant dust suppression effect. The curing layer formed by M-OX can adapt to complex weather, maintains its integrity after rain and wind erosion, and exhibits excellent rain and wind erosion resistance. This study provides an environmentally friendly and effective dust suppression solution for surface coal mines with significant social and economic benefits.

Sustainability assessment of the micellar optimized HPLC method for concomitant quantification of a common triple regimen for cardiovascular disorders: application to marketed formulations and in vitro dissolution testing.

Hypertension and dyslipidemia are two of the most frequently co-occurring cardiovascular risk factors. The combined regimen of hydrochlorothiazide (HCTZ), rosuvastatin (ROS), and losartan (LOS) helped in the successful management of both conditions. This work's objective is to develop an eco-friendly, sensitive, simple, and reliable chromatographic method for the simultaneous estimation of HCTZ, ROS, and the LOS ternary mixture in their pure form, and pharmaceutical formulations. Utilizing sodium dodecyl sulphate (SDS) in combination with polyoxyethylene-23-lauryl ether (Brij-35) could be a greener option with minimal environmental impact in liquid chromatographic separation techniques. Therefore, a micellar HPLC protocol was optimized and validated employing a mobile phase comprising a mixture of micelles of SDS (0.15 mol L-1) and Brij-35 (0.03 mol L-1) with 0.01 M monobasic potassium phosphate buffer, pH 3.5. The cited drugs were detected at 230 nm within five minutes, using a symmetry RP-C18 column, an isocratic elution mode, and a flow speed of 1 mL min-1. Method validation was successfully performed as stated by ICH. The suggested HPLC approach was effectively applied to determine the mentioned drugs in three pharmaceutical preparations. It was also employed for monitoring their in vitro release pattern using two innovator tablet formulations, applying the USFDA guidelines. The applied procedure was evaluated and compared with previously published HPLC approaches using various metrics, including the Eco-Scale Scoring method (AES), the Green Analytical Procedure Index (GAPI), and the Analytical Greenness Calculator (AGREE) for greenness, the most current Blue Applicability Grade Index (BAGI) for blueness, and the more inclusive RGB 12 algorism for whiteness assessment.

Enhancing Droplet Spreading on a Hydrophobic Plant Surface by Surfactant/Cellulose Nanocrystal Complexes.

A surfactant is an efficient and common additive used to enhance the spreading of droplets on hydrophobic surfaces. However, a high surfactant concentration is required to achieve the desired performance, resulting in environmental pollution and increased costs. Additionally, the pesticide loading capacity of surfactants at low concentrations (below their critical micelle concentrations) is a concern. Thus, in this study, we developed a strategy to enhance pesticide loading and droplet deposition by mixing small amounts of sodium dodecyl sulfate (SDS) (0.1 wt %) and cationically modified cellulose nanocrystals (PCNC). The reduced surface tension, increased viscosity and adhesion, and electrostatic and hydrogen interactions resulted in a low retraction velocity, excellent spreading, and resistance to air turbulence. The improved loading content was facilitated by the hydrophobic domains of PCNC and SDS micelles.