Abstract Purpose “Cuban Motion” (CM) is a term often used to label a basic movement of many Latin-American dances, such as salsa and bachata. It is characterized by a cyclical and rhythmic flexion and rotation of the pelvis, accompanied by ample movements of the spine and lower limbs. Since Latin dances are considered both a recreational activity and a kind of healthy gymnastics for young and older subjects, a biomechanical analysis of the CM was performed to quantitatively assess the main features of this movement, from joint kinematics to muscle activations. Method The study combined experimental acquisitions with a Vicon Motion Capture system and musculoskeletal analyses in OpenSim. Only one subject was considered, an instructor of Latin dances, who was equipped with 55 retro-reflective markers, according to the Full Body CGM2.5 marker set. Data were processed in OpenSim, using the ThoracoLumbar model (111 DoFs and 620 musculo-tendon actuators). Results The cycle of the CM and its main events were defined. Results showed a wide RoM of many joints, with correlations between hip and knee flexion angles and among list, between hip adduction and shoulder flexion. The main role of the iliopsoas and the ileus costalis muscles was observed. Conclusions The current study quantified the CM as a physical exercise using a biomechanical approach similar to a gait analysis. The main kinematic and kinetic features were described, also providing an estimation of the muscle activations and joint reactions, derived from simulation activity in OpenSim. The main limitation of this study is the focus on a single subject, but this step was necessary to define a context and guidelines for future investigations, where we are going to compare èlite vs. novices and male vs. female dancers.