Anterior knee pain (AKP) after total knee arthroplasty (TKA) results in dissatisfaction with the surgical outcomes. This study aimed to investigate risk factors for AKP after TKA using radiographic assessments. This retrospective matched-pair, case-control study included 284 patients who underwent primary fixed-bearing, posterior-stabilized TKA from 2016 to 2020, with a minimum follow-up of two years. The inclusion criterion was varus osteoarthritis in the knees without patellar resurfacing. The exclusion criteria were the use of bone graft or metal block, valgus knees, and patellar resurfacing. The patellar tilt angle, lateral patello-femoral angle, length of the tibial tuberosity to the trochlear groove (TT-TG), hip-knee-ankle (HKA) angle, patellar height, and trochlear dysplasia index were measured. Patients were divided into two groups according to the presence of AKP based on the Feller score (≤ 20 points) at a 2-year follow-up, then a 1:2 propensity matching was performed. Risk factors for AKP were identified through a logistic regression analysis. A total of 135 patients were enrolled in this study after matching. The preoperative patellar tilt angle, lateral patello-femoral angle, TT-TG, and trochlear dysplasia index significantly differed between the groups (P < 0.05), but not the postoperative parameters (P > 0.05). The Western Ontario and McMaster Universities total score and Feller score were significantly different postoperatively. (P < 0.05) Logistic regression analysis revealed that the preoperative patellar tilt angle, preoperative trochlear dysplasia index, and preoperative lateral patello-femoral angle were significant risk factors. Care should be exercised when performing TKA in patients who have a large patellar tilt angle, a small lateral patello-femoral angle, and a small trochlear dysplasia index preoperatively, as there can be an increased risk of postoperative anterior knee pain in TKA with unresurfaced patellae. Surgeons may consider counseling patients about their increased risk of AKP if these factors are present preoperatively.
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