Lateral hinge fracture is a significant complication of medial opening wedge high tibial osteotomy. While fracture risk is closely associated with the osteotomy apex position, the optimum position remains variable within the literature. Our hypothesis is that stresses at the osteotomy apex predicted by finite element analysis can be used to identify an apex position which minimises intra and postoperative fracture risks. A finite element model was studied to investigate the effect of varying the hinge position on fracture risk and severity for a given bone geometry; variables analysed included stress, strain and micromotion levels. Nine further knee models were studied to assess the variability between patients' bone properties and examine the effect of apex location on strains. Lateral hinge width and height significantly influence intra-operative stress, strain, and fracture risk, while hinge width predominately determines postoperative stability. Wider hinges improve postoperative stability, but increase the likelihood of intra-articular fractures. Aiming the apex at the fibular head height minimises strain. The osteotomy apex should be located such that the hinge width is equal to 13% of the medial-lateral width to minimise apex stress and fracture risk while preserving sufficient bone at the hinge for stability. The height of the apex from the tibial plateau should maintain a minimum value of 16% of the medial-lateral width to avoid intra-articular fracture, with the apex below the fibula head if necessary. The size of the tibia does not alter the optimal location, making our findings applicable across all tibia sizes. Our study has investigated and verified a proposed optimal apex position, based upon fracture risk prediction and micromotion at the osteotomy apex. This is clinically useful due to the potential use of the apex point on preoperative 2D radiographs when planning surgery. Not applicable.