Every nation is working to stop ozone depletion and global warming as climate changes have just become apparent on a global scale. According to the prevailing theory behind ozone depletion, free chlorine radicals first eliminate ozone from the atmosphere before chlorine atoms continue to turn more ozone into oxygen. The migration of substances containing chlorine is what causes chlorine to be present in the stratosphere. This behaviour is common across a wide class of compounds called hydro chloro fluoro carbons (HCFCs) and chlorofluorocarbons (CFCs). The world's consumers and industries employ these substances in a variety of applications, particularly as refrigerants in air conditioning and refrigeration systems. The optimal refrigerant was chosen in this study using the WASPAS approach. In this paper R152a, R1234yf, R1234ze (E), R1233zd (E), R290, R600a, R744 and R1270 are used as an alternative for refrigerants. Vapour density, Latent heat of vaporization, Thermal conductivity of liquid, Critical Pressure and Saturated pressure are used to evaluate the performance of refrigerants. Rank of refrigerants R152a is third-ranked, R1234yf is ranked fifth, R1234ze (E) is ranked first, R1233zd (E) is fourth ranked, R290 is fourth-ranked, R600a is ranked eighth, R744 is second and R1270 is seventh-ranked. The result of the analysis shows that the best refrigerant is R1234ze (E) with a coefficient value of 0.634741 followed by R744 with a coefficient value of 0.517734.