Late Starters Research Articles

24-Hour Assessment of Performance on a Palmtop Computer: Validating a Self-Constructed Test Battery

A test battery was constructed on a palmtop computer for ambulatory purposes. This study explored whether the test battery could assess circadian rhythmicity under constant routine conditions. Performance, body temperature, and subjective sleepiness of 12 healthy subjects were measured. The test battery consisted of a sleepiness questionnaire and three performance tests: a vigilance detection test, a working memory test, and a choice-reaction time test. The subjects were divided into early-start and late-start groups and were subjected to the constant-routine protocol. All tests showed a trough in performance in the early morning around 07:00h and a peak in the evening between 21:00 and 23:00h. In addition, an afternoon decrement in performance was observed between 15:00 and 17:00h. On average, the circadian (peak-to-trough) variation of the performance variables amounted to 16.9%±1.7 SEM of the maximum across subjects. The late starters showed a larger impairment in performance during the morning than the early starters. This could be attributed to prior wakefulness. The characteristics of the performance rhythms found in this study replicate findings in several other studies carried out under constant routine conditions. In conclusion, the present test battery appeared to be a good tool for future assessment of performance under natural conditions.

Patterns of substance use in early through late adolescence.

This study examined patterns of substance use throughout adolescence. A cluster analytic approach was used to identify subgroups of adolescents on the basis of their levels of substance use from early through late adolescence (Grades 6 through 11). Six distinct clusters of substance users emerged-2 groups representing relatively stable patterns of substance use from early through late adolescence (ie., nonusers and alcohol experimenters), and 4 groups of users showing escalating patterns of substance use (i.e., low escalators, early starters, late starters, and high escalators). The study provides a comprehensive view of adolescent substance use by examining the progression of use from early to late adolescence, demonstrates the usefulness of studying patterns of use across multiple substances, and underscores the importance of building classification schemes based on repeated measurements of substance use to reflect changes over time. Implications of the findings for future research and for identifying high-risk subgroups of adolescents for purposes of intervention based on timing and pattern of escalation are discussed.

Globalisation, social values and human rights NGOs in Nigeria

Globalisation as a social phenomenon has assumed a compelling dimension in the last decade. In this sense, it has been seen as the variable underlying most efforts towards development. especially in the developing nations. The massive spread of globalisation and globalising influences has removed the boundaries between nations and aided the spread of values from one end of the globe to the other. In spite of the ubiquity of this phenomenon, African countries have as usual been seen as late starters. Therefore, the idea of the unevenness of globalisation is often used in descriptionbing the experience of African countries in this regard. Globalisation as a process involves a grand or widespread social change across national boundaries. In other words, it is a socio-political and economic process of change, interchange and interaction between various nations.1 The phenomenon of globalisation in this context should be seen as narrowing the socio-geographic boundaries between nations.

Factors associated with low uptake of measles and pertussis vaccines — an ecologic study based on the Australian Childhood Immunisation Register

To evaluate the relationships between socio-economic and demographic variables and low immunisation coverage at the national level. The Australian Childhood Immunisation Register (ACIR) contains data at the postcode level on the immunisation status of all children registered with Medicare under the age of seven years. The Australian Bureau of Statistics (ABS) produces a number of indicators of socio-economic status at the postcode level from Census data. These and other ABS demographic data were used to examine the relationship between immunisation coverage and various socio-demographic indicators. Factors associated with lower immunisation uptake differed in rural and metropolitan areas. High levels of education and occupation and a high proportion of Aboriginal residents were significantly associated with lower coverage only in metropolitan postcodes. High unemployment was associated with lower immunisation coverage only in rural postcodes. A high proportion of late starters to immunisation was the strongest single predictor of coverage and was important in rural and metropolitan postcodes. A high proportion of overseas-born persons and of GP-delivered immunisations was also associated with lower coverage in all areas. These data suggest that in metropolitan areas, reasons for low uptake in more advantaged areas require further evaluation. In non-metropolitan areas, low coverage was associated with areas of disadvantage, for which access to services may be more important. Children who are late in starting the schedule should be targeted.

When to initiate dialysis: effect of proposed US guidelines on survival

Recent guidelines from the US National Kidney Foundation Dialysis Outcomes Quality Initiative recommend an earlier start of dialysis treatment than has been common practice. Their implementation would have a substantial effect on patients' daily lives and would increase costs. The guidelines are largely opinion-based, because evidence is still lacking. As part of a prospective multicentre study in the Netherlands, we included, between January, 1997, and May, 1999, all new patients with end-stage renal disease, for whom data were available on residual renal function 0-4 weeks before the start of dialysis. We recorded date of death or censoring until August, 2000. 94 (37%) of 253 patients started dialysis treatment later than recommended by the US guideline. There was an increased mortality risk for these patients compared with those who started dialysis on time, although it was not significant (adjusted hazard ratio 1.66 [95% CI 0.95-2.89]). The adjusted difference in estimated survival time after 3 years on dialysis treatment was 2.5 months (1.1-4.0) in favour of timely starters. Conversely, the average delay in dialysis initiation for late starters, the extra time free of dialysis, was at least 4.1 months. Although we observed a gain in survival time with a timely start of dialysis, it is probably a reflection of initiating dialysis earlier in the disease. We question the benefit of putting this guideline into daily practice, given the current clinical evidence and the effects it would have on patients and dialysis resources.

Male criminals with organic brain syndrome: two distinct types based on age at first arrest.

This study examined whether criminals with organic brain syndrome could be divided into two distinct types. The authors proposed that early starters (onset of criminal activity by age 18) would display a persistent, long-lasting pattern of deviance that was largely independent of their brain disorder, whereas late starters (onset at age 19 or after) would exhibit deviant behaviors that began late in life and were more directly related to their brain disorder. Subjects were 1,130 male criminal offenders drawn from a birth cohort of all individuals born between January 1, 1944, and December 31, 1947, in Denmark. The main study group included all men with both a history of criminal arrest and a hospitalization for organic brain syndrome (N=565). In addition, for a subset of analyses, the authors examined a randomly selected, same-size comparison group of men with a history of criminal arrest who were not hospitalized for organic brain syndrome. Data were available on all arrests and all psychiatric hospitalizations for individuals in this cohort through the age of 44. Among those with organic brain syndrome, early starters were significantly more likely than late starters to 1) be arrested before the onset of organic brain syndrome, 2) show a higher rate of offending before but not after the onset of organic brain syndrome, 3) be both recidivists and violent recidivists, and 4) have a diagnosis of antisocial personality disorder. Male criminals with organic brain syndrome can be meaningfully divided into two distinct types on the basis of age at first arrest. Early starters show a more global, persistent, and stable pattern of offending than late starters. These results have implications for treatment and risk assessment.

Men with Schizophrenia Who Behave Violently: The Usefulness of an Early- Versus Late-Start Offender Typology

Persons who develop schizophrenia are more likely than nondisordered persons to commit crimes. It is important to investigate those who offend, in order to develop treatment programs that effectively prevent recidivism, and eventually, early childhood violence prevention programs. Recent studies have shown that among offenders with major mental disorders, there are two groups: early starters, who begin their criminal careers in adolescence; and late starters, who first offend as adults. The present study examined 272 violent male offenders with schizophrenia in Sweden who underwent a pretrial psychiatric assessment between 1988 and 1995. Early- and late-start offenders were found to present differences in behavior, comorbid disorders, personality traits, and referrals for treatment in childhood, adolescence, and adulthood. Their parents also differed. The findings have implications for treatment and management of offenders with schizophrenia, for risk assessment, and for prevention.

Policy Directions for the New Economic Model in Latin America

The new economic model (NEM) has been extremely successful in reducing inflation and in increasing exports, but quite disappointing in terms of the growth of output and productivity. It is argued that this calls for a “second generation” of reforms, especially centered at the plant level and its surrounding factor markets, to close the huge productivity gap separating firms from best practice and so enable the accelerated growth rates typical of successful “late starters.” Policies should emphasize the systematic identification of those technologies and practices best suited to local conditions and their rapid transfer, adaptation and diffusion throughout the economy.

Evidence for a genetic etiology of early-onset delinquency.

Age at onset of antisocial behavior discriminates persistent and transitory offenders. The authors proposed that early-onset delinquency has an underlying genetic influence that manifests in problems related to inhibition, whereas late-onset delinquency is more environmentally mediated. To test these notions, they selected 36 early starters, 86 late starters, and 25 nondelinquent controls from a large sample of 11-year-old twins and compared them on several measures related to inhibition and a peer group measure. As expected, early starters had more psychological, behavioral, and emotional problems related to inhibition than late starters and controls. A longitudinal analysis indicated an increase an antisocial behavior among peers of late starters shortly before their delinquency onset. Family history data and a twin analysis provided evidence of greater genetic influence on early-onset than late-onset delinquency.

Tackling the problem

Catalogues, that, since 1995‐96 Y2K projects methodology has been developed and widely adopted and covers the following stages: awareness; assessment; inventory and analysis; planning and scheduling; renovation or remediation; validation through internal testing; implementation; and final validation through external testing. States that may IT managers avoid admitting there is a problem until it is too late and that the Y2K problem does not allow for late starters in the area.

Comparison of Early and Late Start Models of Delinquency in Adult Offenders

This study examines the validity of the early and late start models of delinquency in adult offenders. Subjects were 180 adult maximum-security inmates who provided information regarding adult and juvenile criminal history, familial and childhood factors, and medical history. Significant differences were found between early starters, late starters, and nondelinquents for substance abuse, diagnoses of antisocial personality, childhood conduct disorder, attention deficit hyperactivity disorder, and childhood violence. Differences were also found in family history of criminality and substance abuse as well as childhood physical and sexual abuse. The utility of the early and late start models in identifying clinical issues in adult offenders is discussed.

Exploring the Time Preferences by Procrastinators: Night or Day, Which is the One?

In study 1, trait procrastinators compared to nonprocrastinators claimed they were ‘night persons’, individuals who are most alert and active in the late afternoon and evening hours. However, there were no significant individual differences in time preference for a set of social and individual activities considered pleasurable. In study 2, participants kept daily records for six straight days of when they had engaged in activities. Proneness toward behavioral (but not decisional) procrastination was significantly related to number of activities performed in the evening. Together, these studies suggest that procrastinators may be ‘late starters’ who prefer to engage in daily activities later in the day than early in the morning. © 1997 John Wiley & Sons, Ltd.

Escalated substance use: A longitudinal grouping analysis from early to middle adolescence.

The authors surveyed a cohort of 1,184 adolescents in the 7th, 8th, and 9th grades. Measures of tobacco, alcohol, and marijuana use and of constructs from 3 theoretical models of substance use were obtained at each point. Clustering analysis for 3-wave substance use data indicated subgroups of nonusers, minimal experimenters, late starters, and escalators. Discriminant function analyses tested whether study variables differentiated the subgroups. One discriminant function accounted for the majority of between-group association; it had loadings for (high) life stress, nonadaptive coping, deviance-prone attitudes, and parental and peer substance use, and (low) parental support, academic competence, and behavioral control. Escalators were high on this function; late starters and experimenters had intermediate values; and nonusers were low on the function. Implications for theories of vulnerability to substance abuse are discussed.

Smoking, alcohol consumption and the risk of cancer of the biliary tract; a population-based case-control study in The Netherlands.

Although cancer of the biliary tract is a highly fatal disease, the relationship with modifiable, life style-related factors is hardly studied. Between 1984 and 1987 we conducted a case-control study of 114 patients and 487 controls from the general population. An interviewer-administered questionnaire was used to collect information on life-time smoking habits and life-time alcohol consumption. The information was obtained either from the subjects themselves (direct response) of from relatives (indirect response). Results show that neither smoking at the time of interview (odds ratio (OR) 1.5; 95% confidence interval (CI) 0.9-2.4) nor smoking 2, 5 or 10 years before were associated significantly with the cancer. Alcohol consumption at the time of interview (OR 1.0; 95% CI 0.6-1.5) or drinking 2, 5 or 10 years before were not significantly associated either. Among current alcohol drinkers, long-term consumers had a reduced risk (duration of use > 38 years vs < 25 years: OR 0.4; 95% CI 0.1-0.9) and late starters an elevated risk (starting age > 38 years vs < 21 years: OR 2.7, 95% CI 1.0-7.5). A modifying effect of alcohol consumption on the smoking-cancer relationship was observed: the risk for current smokers was increased only when they did not drink alcohol at that point in time (OR 3.4, 95% CI 1.3-8.5). Our results indicate that long-term moderate alcohol use might be protective against cancer of the biliary tract, whereas smoking might be a risk factor for this cancer.

TWO ROUTES TO DELINQUENCY: DIFFERENCES BETWEEN EARLY AND LATE STARTERS IN THE IMPACT OF PARENTING AND DEVIANT PEERS*

This paper tests hypotheses concerning differences in the determinants of involvement with the criminal justice system for adolescents who show early versus late onset of delinquency. Four waves of data collected on 177 adolescent boys living in small towns in the midwest were used to test the hypotheses. For late starters, quality of parenting predicted affiliation with deviant peers, which was associated in turn with criminal justice system involvement. Oppositional/defiant behavior was unrelated both to affiliation with deviant peers and to involvement with the criminal justice system. For early starters, on the other hand, quality of parenting predicted oppositional/defiant behavior. This behavior pattern predicted affiliation with deviant peers, which in turn predicted criminal justice system involvement. Further, we found evidence of an interaction effect for early starters: criminal justice system involvement was highest for those youths who both were oppositional/defiant and had deviant friends. Overall the findings support the idea of different routes to criminal behavior and arrest for early versus late starters.

Childhood immunisation: factors associated with failure to complete the recommended schedule by two years of age

This study aimed to determine the immunisation status of preschool-aged children attending formal child-care facilities in north Queensland, and to examine factors associated with failure to be completely immunised by two years of age. Child-care centres and kindergartens within the Cairns City and Mulgrave Shire local government boundaries were selected randomly with probability proportional to size, and 613 children (median age of 47.0 months) were selected randomly from the facilities. Only 60.3 per cent (95 per cent confidence interval (CI) 56.3 to 64.3) of the children were fully immunised by two years of age. Children who had not received any vaccines by three months of age (that is, 'late starters') were less likely to be fully up-to-date at two years of age than children who started on time (odds ratio (OR) 10.3; CI 5.2 to 20.9). Children without a parent-held immunisation record were less likely to be up-to-date at two years of age than those children with a parent-held immunisation record (OR 2.8; CI 1.9 to 4.0). With follow-up of late-starters, and with the simultaneous administration of overdue vaccines with vaccines given in the second year of life, the percentage of children up-to-date at 24 months of age could have increased from 60.3 per cent to 82.3 per cent (CI 79.1 to 85.5). The immunisation coverage rates were inadequate to prevent outbreaks of vaccine-preventable diseases. Innovative strategies will be required if the vaccine coverage rates are to be improved. The parent-held immunisation record is of fundamental importance to all these strategies.

Institutions for Sustainable Development

A critical discussion is presented of the dimensions of the concept 'sustainable development'. The concept is shown often to confuse constituents of well being with its determinants, and to be unclear with respect to the level and rate of growth of sustainability. The roles of population growth, technical progress and changes in preferences are often ignored. Principal threats to countries are then enumerated. The poor are identified as both the main cause and the victims of environmental degradation. Options in the alleged choice between economic growth and environmental protection are presented, and it is argued that higher growth may be needed for environmental protection. The technical question of the relation between growth and pollution, the physical question of the relation between pollution and the environment and the biological question of the relation between the environment and human beings are raised. As a consequence of these factual questions, the relation between income and degradation has to be evaluated. Several policies are then presented, including the problems of late starters, the international location of 'dirty' processes and the role of prices and of transnational corporations. Finally, the need for global institutions (such as the Global Environmental Facility) is elaborated within the context of prisoners' dilemma outcomes and free rider problems.

Age at first birth and lifetime fertility.

SummaryAmong a national sample of Canadian women in the Canadian National Fertility Survey of 1984, the excess cumulative fertility of those who started their families early over others has steadily decreased. A difference of approximately two births between early and late starters among older women is reduced to approximately half a child among the younger women. Except for those who start childbearing after age 25, there is little evidence of attempts to catch up after age 30, irrespective of starting age.

36] Location of gene expression in CNS using hybridization histochemistry

In this chapter we have placed heavy emphasis on our own recent work to lay out a workable recipe for hybridization histochemistry. Only a trickle of papers followed the initial benchmark excursions into in situ labeling of tissue sections. Our own entry into this field was as late starters in 1978, but since then a confluence of important questions and technical advances has served to make hybridization histochemistry much more attractive and universally applicable as a research tool. Hybridization histochemistry allows the location of anatomical sites of gene expression and viral replication with unique specificity and is able to solve some problems for which there is no other suitable technique available in the central nervous system. For example, allowing that peptides may enter neurons by a variety of mechanisms and then be christened neuroendocrine peptides, it has become a compelling issue to know which cells are manufacturing the peptide. Thus, much can be learned by the approach elegantly demonstrated by Gee et al., of locating mRNA and its peptide product within the same neuron. The intracellular location of specific mRNA for a neuropeptide in a cell body indicates a very high probability that the peptide is secreted as a neurotransmitter or a neuromodulator from sites associated with the cell body. Our introduction of the use of whole mouse sections and large sections of brain of large animals in hybridization histochemistry has great potential in locating hormonal, enzymatic, and growth factor gene expression. The technique has been applied most elegantly by others to developmental studies and for the examination of viral infection. Resolution down to a single cell in heterogeneous tissue was beyond the original expectation of the capability of 32P-labeled probes and single cells in sections shown in Fig. 2 is probably the limit of resolution with this isotope. There is no reason why other isotopes, fluorescent labels, or labels suitable for EM should not take the resolution of the technique to intracellular. The horizon of application is widened enormously by the successful application of synthetic oligonucleotide probes, and at the same time unshackles the procedure from dependence upon a fully functional molecular biology laboratory. Although hybridization is a valuable research tool which we have applied to location of neuropeptides in the brain, it should soon find a niche in many fields and in a short time should become a key diagnostic tool.(ABSTRACT TRUNCATED AT 400 WORDS)

Performance models for antisocial boys.

VioLit summary: OBJECTIVE: This article by Patterson tested and analyzed three structural equation models designed to examine antisocial behavior in children. METHODOLOGY: A quasi-experimental design was used for this study. The author conducted a literature review of material on antisocial behavior. In addition, the research utilized secondary data to test and analyze the study's models. FINDINGS/DISCUSSION: The research rested on three assumptions of antisocial children: aggression scores for children are stable; antisocial behavior covaries with peer rejection, academic problems, and low self-esteem; and parents of antisocial children lack effective family management skills. The author hypothesized that poor family management skills lead to antisocial behavior in children. He argued that this behavior leads to peer rejection, school failure, and rejection by the parents. It was stated that these factors produce low self-esteem. The study further hypothesized that low self-esteem, peer rejection, and school failure put the child at risk for greater problems. To test these hypotheses the study developed performance models and built component constructs. The study presented the findings from the three structural equation models. The first model was the basic training model. It was shown that this model assumes that antisocial behavior is learned and the initial basic training ground is the home. It focused on parents' discipline techniques and parenting skills and their relation to children's antisocial behavior. It was argued that parents who fail to punish coercive behavior start a coercion process. The study presumed that more effective discipline would decrease antisocial behavior. The findings supported this model. The author felt confident that the model was reliable and robust. It was shown that the data provided a fit to the theory-driven model. The second model focused on the relationship between antisocial behavior and disruptions with peers, school, and self-esteem. The study posited that antisocial behavior's coercive and noncompliant core creates these disruptions. It was shown that normal peer relations, academic progress, and self-esteem levels suffer because of noncompliance and coercive exchanges. The author stated that this is a simplistic model as it is simply testing if indeed antisocial behavior is related to low self-esteem, lack of peer acceptance, and academic incompetence. The research reported that the findings supported this model. The third model discussed variables related to disruptions in parenting skills. The study placed these variables into and categories. The early onset variables included difficult child temperament, families with social disadvantages, and inept training in parenting. For the late starters category the variables included two problems in parents' family management skills. These two disruptors were stressors and parent substance abuse. Stressors included factors such as divorce, unemployment, medical problems, and daily hassles. It showed that parents' ineffective family management skills initiate the process of peer, school, and self-esteem problems for children. The author stated that the findings also supported this model. AUTHOR'S RECOMMENDATIONS: The author noted that the third model was effective for analysis of single-parent families but not for intact families. He recommended that a new, more complex model be developed to fit intact families. The study suggested that the new model include multiple indicators of support or buffering and family problem-solving skills. The researcher noted that these variables are being considered in current studies. (CSPV Abstract - Copyright © 1992-2007 by the Center for the Study and Prevention of Violence, Institute of Behavioral Science, Regents of the University of Colorado) Male Behavior Male Aggression Male Antisocial Behavior Model Child Antisocial Behavior Child Aggression Child Behavior Child Male Child Problem Behavior Behavior Causes Family Relations Parent Child Relations Parental Rejection Peer Relations Peer Rejection Child Self-Esteem School Achievement School Performance Parenting Skills Aggression Causes 03-05