SummaryRetinal Angiomatous Proliferations (RAP) have been described initially on ophthalmoscopy as a chorioretinal anastomosis in a late stage of AMD and of MACTEL. Fluorescein angiography evidences a dilated perimacular retinal capillary with late profuse leakage of dye. ICG angiography is instrumental to detect Retinal Angiomatous Proliferation at an early stage of development, especially in AMD. A localized effraction of the RPE on OCT evidences the communication between retinal and choroidal circulation with massive fluid infiltration of the retina. The basic idea of OCT angiography was to separate moving objects from static tissue. This new technic is suitable for 3D segmentation and reconstruction of the retinal capillary layers. There are a number of questions that OCTA may help to solve. What is the participation of the deep retinal capillary plexus to the clinically visible RAP? Is the portion perpendicular to the retinal plane a capillary of the intermediate layer? Does RAP involving only the deep retinal plexus exist? Is the PED part of the process? OCTA may be of great value to the understanding of the pathophysiology of the early stage of the disorder and may offer noninvasive monitoring of the disease progression and activity, aiding for each treatment assessment.