Laser-driven Proton Research Articles

Improving laser-accelerated proton beam divergence by electric and magnetic fields induced in flat channel-like targets

Improving parameters of laser-driven proton and ion beams becomes one of the most important goals in the field of laser acceleration in order to fulfill requirements of foreseen applications. This work presents parametric 2D and 3D particle-in-cell simulations of various target designs in order to reduce proton beam divergence without significant drop in maximum energies or in proton number. The optimal target design proved to be a channel-like target which produces not only a long-lasting focusing transverse electric field in contrast to a flat foil, but also a magnetic quadrupole with strong octupole component inside the guiding channel. A combination of both electric and magnetic features results in a strong proton beam divergence reduction, accompanied by a higher uniformity of the beam, which is studied as a function of proton energy.

Energetic α-particle sources produced through proton-boron reactions by high-energy high-intensity laser beams.

In an experiment performed with a high-intensity and high-energy laser system, α-particle production in proton-boron reaction by using a laser-driven proton beam was measured. α particles were observed from the front and also from the rear side, even after a 2-mm-thick boron target. The data obtained in this experiment have been analyzed using a sequence of numerical simulations. The simulations clarify the mechanisms of α-particle production and transport through the boron targets. α-particle energies observed in the experiment and in the simulation reach 10-20 MeV through energy transfer from 20-30 MeV energy incident protons. Despite the lower cross sections for protons with energy above the sub-MeV resonances in the proton-boron reactions, 10^{8}-10^{9}α particles per steradian have been detected.

High-quality GeV proton beam generation from multiple-laser interaction with double-layer target

A scheme for significantly enhancing the beam quality of laser-driven proton acceleration is proposed and investigated with particle-in-cell simulation: two linearly polarized Gaussian laser pulses obliquely irradiate a double-layer target that acquires a periodic surface structure that reduces the reflection, improves the focusing, and enhances the energy coupling of the third, or main, laser pulse that follows. The oblique pulses also provide some initial kinetic energy to the initially static target electrons and thus protons, which is very crucial for efficient acceleration. As a result, a proton beam of 1.15 GeV peak energy, very low energy spread ∼4%, and small divergence angle ∼5° can be obtained with laser intensities of 1021 W cm−2, which is significantly lower than that of the other recently proposed schemes.

Radiobiology Experiments With Ultra-high Dose Rate Laser-Driven Protons: Methodology and State-of-the-Art

The use of particle accelerators in radiotherapy has significantly changed the therapeutic outcomes for many types of solid tumours. In particular, protons are well known for sparing normal tissues and increasing the overall therapeutic index. Recent studies show that normal tissue sparing can be further enhanced through proton delivery at 100 Gy/s and above, in the so-called FLASH regime. This has generated very significant interest in assessing the biological effects of proton pulses delivered at very high dose rates. Laser-accelerated proton beams have unique temporal emission properties, which can be exploited to deliver Gy level doses in single or multiple pulses at dose rates exceeding by many orders of magnitude those currently used in FLASH approaches. An extensive investigation of the radiobiology of laser-driven protons is therefore not only necessary for future clinical application, but also offers the opportunity of accessing yet untested regimes of radiobiology. This paper provides an updated review of the recent progress achieved in ultra-high dose rate radiobiology experiments employing laser-driven protons, including a brief discussion of the relevant methodology and dosimetry approaches.

Laser-driven proton acceleration from ultrathin foils with nanoholes

Structured solid targets are widely investigated to increase the energy absorption of high-power laser pulses so as to achieve efficient ion acceleration. Here we report the first experimental study of the maximum energy of proton beams accelerated from sub-micrometric foils perforated with holes of nanometric size. By showing the lack of energy enhancement in comparison to standard flat foils, our results suggest that the high contrast routinely achieved with a double plasma mirror does not prevent damaging of the nanostructures prior to the main interaction. Particle-in-cell simulations support that even a short scale length plasma, formed in the last hundreds of femtoseconds before the peak of an ultrashort laser pulse, fills the holes and hinders enhanced electron heating. Our findings reinforce the need for improved laser contrast, as well as for accurate control and diagnostics of on-target plasma formation.

Enhanced laser-driven proton acceleration using nanowire targets

Laser-driven proton acceleration is a growing field of interest in the high-power laser community. One of the big challenges related to the most routinely used laser-driven ion acceleration mechanism, Target-Normal Sheath Acceleration (TNSA), is to enhance the laser-to-proton energy transfer such as to maximize the proton kinetic energy and number. A way to achieve this is using nanostructured target surfaces in the laser-matter interaction. In this paper, we show that nanowire structures can increase the maximum proton energy by a factor of two, triple the proton temperature and boost the proton numbers, in a campaign performed on the ultra-high contrast 10 TW laser at the Lund Laser Center (LLC). The optimal nanowire length, generating maximum proton energies around 6 MeV, is around 1–2 upmum. This nanowire length is sufficient to form well-defined highly-absorptive NW forests and short enough to minimize the energy loss of hot electrons going through the target bulk. Results are further supported by Particle-In-Cell simulations. Systematically analyzing nanowire length, diameter and gap size, we examine the underlying physical mechanisms that are provoking the enhancement of the longitudinal accelerating electric field. The parameter scan analysis shows that optimizing the spatial gap between the nanowires leads to larger enhancement than by the nanowire diameter and length, through increased electron heating.

High energy implementation of coil-target scheme for guided re-acceleration of laser-driven protons

Developing compact ion accelerators using intense lasers is a very active area of research, motivated by a strong applicative potential in science, industry and healthcare. However, proposed applications in medical therapy, as well as in nuclear and particle physics demand a strict control of ion energy, as well as of the angular and spectral distribution of ion beam, beyond the intrinsic limitations of the several acceleration mechanisms explored so far. Here we report on the production of highly collimated (sim 0.2^{circ } half angle divergence), high-charge (10s of pC) and quasi-monoenergetic proton beams up to sim 50 MeV, using a recently developed method based on helical coil targetry. In this concept, ions accelerated from a laser-irradiated foil are post-accelerated and conditioned in a helical structure positioned at the rear of the foil. The pencil beam of protons was produced by guided post-acceleration at a rate of sim 2 GeV/m, without sacrificing the excellent beam emittance of the laser-driven proton beams. 3D particle tracing simulations indicate the possibility of sustaining high acceleration gradients over extended helical coil lengths, thus maximising the gain from such miniature accelerating modules.

Experimental progress of laser-driven high-energy proton acceleration and new acceleration schemes

The acceleration of high-energy ions by the interaction of plasma with ultra-intense laser pulses is a frontier in the fields of laser plasma physics and accelerator physics. Laser-driven ion acceleration has achieved great success and triggered plenty of new applications after nearly twenty years’ development. This paper reviews the important experimental progress of laser-driven high-energy proton acceleration, discusses some critical issues that influence the acceleration. It also gives an introduction to new acceleration schemes developed in recent years, which promise to generate over 200 MeV protons.

Scaling of laser-driven electron and proton acceleration as a function of laser pulse duration, energy, and intensity in the multi-picosecond regime

A scaling study of short-pulse laser-driven proton and electron acceleration was conducted as a function of pulse duration, laser energy, and laser intensity in the multi-picosecond (ps) regime (∼0.8 ps–20 ps). Maximum proton energies significantly greater than established scaling laws were observed, consistent with observations at other multi-ps laser facilities. In addition, maximum proton energies and electron temperatures in this regime were found to be strongly dependent on the laser pulse duration and preplasma conditions. A modified proton scaling model is presented that is able to better represent the accelerated proton characteristics in this multi-ps regime.

Laser-driven x-ray and proton micro-source and application to simultaneous single-shot bi-modal radiographic imaging

Radiographic imaging with x-rays and protons is an omnipresent tool in basic research and applications in industry, material science and medical diagnostics. The information contained in both modalities can often be valuable in principle, but difficult to access simultaneously. Laser-driven solid-density plasma-sources deliver both kinds of radiation, but mostly single modalities have been explored for applications. Their potential for bi-modal radiographic imaging has never been fully realized, due to problems in generating appropriate sources and separating image modalities. Here, we report on the generation of proton and x-ray micro-sources in laser-plasma interactions of the focused Texas Petawatt laser with solid-density, micrometer-sized tungsten needles. We apply them for bi-modal radiographic imaging of biological and technological objects in a single laser shot. Thereby, advantages of laser-driven sources could be enriched beyond their small footprint by embracing their additional unique properties, including the spectral bandwidth, small source size and multi-mode emission.

Scintillator detector characterization for laser-driven proton beam imaging

The spatial resolution and imaging characteristics of plastic scintillators are characterized using laser-driven proton beams. Laser-driven proton beams typically have broad energy spectra and are accompanied by relativistic electrons and high-energy photons, both potentially contributing to background noise. Different types and thicknesses of Eljen Technology scintillators are compared to determine their intrinsic point spread function. Point-projection imaging of a mesh is used to compare the imaging resolution of the scintillator to the usual imaging detector, radiochromic film, and is found to be reasonably comparable and sufficient for many experimental applications.

Enhanced laser-driven proton acceleration with gas–foil targets

We study numerically the mechanisms of proton acceleration in gas–foil targets driven by an ultraintense femtosecond laser pulse. The target consists of a near-critical-density hydrogen gas layer of a few tens of microns attached to a $2\ \mathrm {\mu }$ m-thick solid carbon foil with a contaminant thin proton layer at its back side. Two-dimensional particle-in-cell simulations show that, at optimal gas density, the maximum energy of the contaminant protons is increased by a factor of $\sim$ 4 compared with a single foil target. This improvement originates from the near-complete laser absorption into relativistic electrons in the gas. Several energetic electron populations are identified, and their respective effect on the proton acceleration is quantified by computing the electrostatic fields that they generate at the protons’ positions. While each of those electron groups is found to contribute substantially to the overall accelerating field, the dominant one is the relativistic thermal bulk that results from the nonlinear wakefield excited in the gas, as analysed recently by Debayle et al. (New J. Phys., vol. 19, 2017, 123013). Our analysis also reveals the important role of the neighbouring ions in the acceleration of the fastest protons, and the onset of multidimensional effects caused by the time-increasing curvature of the proton layer.

Achromatic beamline design for a laser-driven proton therapy accelerator

A new laser-driven proton therapy facility is being designed by Peking University. The protons will be produced by laser--plasma interaction, using a 2-PW laser to reach proton energies up to 100 MeV. We hope that the construction of this facility will promote the real-world applications of laser accelerators. Based on the experimental results and design experience of existing devices in Peking University, we propose a beam transmission system which is suitable for the beam produced by laser acceleration, and demonstrate its feasibility through theoretical simulation. It is designed with two transport lines to provide both horizontal and vertical irradiation modes. We have used a locally-achromatic design method with new canted-cosine-theta (CCT) magnets. These two measures allow us to mitigate the negative effects of large energy spread produced by laser-acceleration, and to reduce the overall weight of the vertical beamline. The beamline contains a complete energy selection system, which can reduce the energy spread of the laser-accelerated beam enough to meet the application requirements. The users can select the proton beam energy within the range 40--100 MeV, which is then transmitted through the rest of the beamline. A beam spot with diameter of less than 15 mm and energy spread of less than 5% can be provided at the horizontal and vertical irradiation targets.

Physics of chromatic focusing, post-acceleration and bunching of laser-driven proton beams in helical coil targets

To increase the fluence and maximum energy of laser-driven proton beams in view of potential applications such as isochoric heating of dense material or isotope production, it has been proposed to attach a helical coil normally to the rear side of the irradiated target. By driving the target discharge current pulse through the coil, this scheme allows a fraction of the proton beam to be selected in energy and to be focused and further accelerated. The previously published results are extended to higher laser pulse energies and longer coils. This leads to an increased number of guided protons and the generation of several proton bunches. Large scale particle-in-cell simulations with realistic boundary conditions reproduce well the experimental results. A detailed analysis of the numerical simulations and an analytical model demonstrate that the current propagation along a helical wire differs from the one of a linear or folded wire. In a helical wire, the current pulse is subject to velocity dispersion, which results in progressive modification of its spatial profile, and so in proton bunch trapping and focusing.

Enhanced laser intensity and ion acceleration due to self-focusing in relativistically transparent ultrathin targets

Laser-driven proton acceleration from ultrathin foils is investigated experimentally using F/3 and F/1 focusing. Higher energies achieved with F/3 are shown via simulations to result from self-focusing of the laser light in expanding foils that become relativistically transparent, enhancing the intensity. The increase in proton energy is maximised for an optimum initial target thickness, and thus expansion profile, with no enhancement occurring for targets that remain opaque, or with F/1 focusing to close to the laser wavelength. The effect is shown to depend on the drive laser pulse duration.

Proton beams from intense laser-solid interaction: Effects of the target materials

We report systematic studies of laser-driven proton beams produced with micrometer-thick solid targets made of aluminum and plastic, respectively. Distinct effects of the target materials are found on the total charge, cutoff energy, and beam spot of protons in the experiments, and these are described well by two-dimensional particle-in-cell simulations incorporating intrinsic material properties. It is found that with a laser intensity of 8 × 1019 W/cm2, target normal sheath acceleration is the dominant mechanism for both types of target. For a plastic target, the higher charge and cutoff energy of the protons are due to the greater energy coupling efficiencies from the intense laser beams, and the larger divergence angle of the protons is due to the deflection of hot electrons during transport in the targets. We also find that the energy loss of hot electrons in targets of different thickness has a significant effect on the proton cutoff energy. The consistent results obtained here further narrow the gap between simulations and experiments.

Laser-driven proton acceleration via excitation of surface plasmon polaritons into TiO2 nanotube array targets

In this paper we report the measurement of laser-driven proton acceleration obtained by irradiating nanotube array targets with ultrashort laser pulses at an intensity in excess of 1020 W cm−2. The energetic spectra of forward accelerated protons show a larger flux and a higher proton cutoff energy if compared to flat foils of comparable thickness. Particle-In-Cell 2D simulations reveal that packed nanotube targets favour a better laser-plasma coupling and produce an efficient generation of fast electrons moving through the target. Due to their sub-wavelength size, the propagation of e.m. field into the tubes is made possible by the excitation of Surface Plasmon Polaritons, travelling down to the end of the target and assuring a continuous electron acceleration. The higher amount and energy of these electrons result in turn in a stronger electric sheath field on the rear surface of the target and in a more efficient acceleration of the protons via the target normal sheath acceleration mechanism.

Ultrafast dynamics and evolution of ion-induced opacity in transparent dielectrics

Recently, measurements of few-picosecond (ps, 10−12 s) pulses of laser-driven protons were realised by the observation of transient opacity in SiO2. This ultrafast response could be understood by the formation of self-trapped excitonic states in the material, creating a rapid de-excitation channel for conduction band electrons. Here we extend this work to examine the onset and evolution of an ion-induced opacity in transparent dielectrics, namely multicomponent variants of SiO2. The fast recovery observed in SiO2 is in sharp contrast to borosilicate (BK7) and soda-lime glasses. We find that the opacity decay timescales for BK7 and soda-lime glass are orders of magnitude greater than the 3.5 ps proton pump pulse duration and discuss the underlying processes which may be affecting the extended recovery of the material. Simultaneous probing with 2nd harmonic radiation allows estimates of ultrafast electron dynamics due to proton interactions in matter to be investigated, this indicates that a rapid evolution of an initially unstructured ion-induced dose distribution seeds the longer term recovery pathways in the irradiated dielectrics. When combined, these results demonstrate the efficacy of utilising ultrafast laser-driven ionising radiation along with highly synchronised probe pulses to enable the study of ion-induced damage in matter on ultrafast timescales in real time.

Challenges in dosimetry of particle beams with ultra-high pulse dose rates

Recent results from pre-clinical studies investigating the so-called FLASH effect suggest that the ultrahigh pulse dose rates (UHPDR) of this modality reduces normal tissue damage whilst preserving tumour response, when compared with conventional radiotherapy (RT). FLASH-RT is characterized by average dose rates of dozens of Gy/s instead of only a few Gy/min. For some studies, dose rates exceeding hundreds of Gy/s have been used for investigating the tissue response. Moreover, depending on the source of radiation, pulsed beams can be used with low repetition rate and large doses per pulse. Accurate dosimetry of high dose-rate particle beams is challenging and requires the development of novel dosimetric approaches, complementary to the ones used for conventional radiotherapy. The European Joint Research Project “UHDpulse” will develop a measurement framework, encompassing reference standards traceable to SI units and validated reference methods for dose measurements with UHPDR beams. In this paper, the UHDpulse project will be presented, discussing the dosimetric challenges and showing some first results obtained in experimental campaigns with pulsed electron beams and laser-driven proton beams.

Effects of oblique incidence and colliding pulses on laser-driven proton acceleration from relativistically transparent ultrathin targets

The use of ultrathin solid foils offers optimal conditions for accelerating protons to high energies from laser–matter interactions. When the target is thin enough that relativistic self-induced transparency sets in, all of the target electrons get heated to high energies by the laser, which maximizes the accelerating electric field and therefore the final ion energy. In this work, we first investigate how ion acceleration by ultraintense femtosecond laser pulses in transparent CH $_2$ solid foils is modified when turning from normal to oblique ( $45^\circ$ ) incidence. Due to stronger electron heating, we find that higher proton energies can be obtained at oblique incidence but in thinner optimum targets. We then show that proton acceleration can be further improved by splitting the laser pulse into two half-pulses focused at opposite incidence angles. An increase by ${\sim }30\,\%$ in the maximum proton energy and by a factor of ${\sim }4$ in the high-energy proton charge is reported compared to the reference case of a single normally incident pulse.