INTRODUCTION: The Brooklyn Hospital Center (TBHC) serves an ethnically diverse community with a large Polish immigrant population. There was a perceived increased quantity of polyps in our Polish patients. Multiple adenomas, larger sized adenomas, and adenomas with advanced histology on index colonoscopy are associated with increased risk for colorectal cancer (CRC). Studies in African Americans demonstrated higher incidence of CRC and mortality compared to whites suggesting different ethnic groups may be at increased risk for CRC. The goal of our study is to see if the Polish population is at increased risk for adenomatous polyps, large polyps(≥1 cm), multiple adenomas(≥3), or advanced adenomas(tubulovillous, villous, or high grade dysplasia) when compared to the non-Polish white population. METHODS: A retrospective chart review was performed from 1/2012 to 10/2018. Inclusion criteria were patients ≥50 years of age undergoing screening colonoscopy. Exclusion criteria consisted of an incomplete exam, personal or family history of CRC, or indication other than screening. Polish and non-Polish whites were identified by demographic data. 121 Polish patients were matched to 121 non-Polish white patients by gender and age. High-risk patients were those having large, multiple or advanced adenomas. Statistical analysis utilized student’s 2 sample t-test for P-values, with an alpha level of 0.05, and odds ratios (OR) with 95% confidence intervals (CI). RESULTS: Each arm consisted of 56 men (46%) and 65 women (54%) with an average age of 64.3 years in both. There was a statistically significant difference between the number of high-risk Polish vs. non-Polish white patients (OR 1.95, 95% CI: 1.07-3.53; P = 0.026). Although not statistically significant, Polish patients had an increased prevalence of total polyps (OR 1.22, 95% CI: 0.73-2.0; P = 0.23), large polyps (OR 1.69, 95% CI:0.88-3.22; P = 0.10), adenomas (OR 1.38, 95% CI: 0.81-2.32; P = 0.23), multiple adenomas (OR 1.63, 95% CI: 0.60-4.35; P = 0.33), and advanced adenomas (OR 1.85, 95% CI: 0.74-4.58; P = 0.18). We also found 2 cases of CRC in the Polish group and no cases in the non-Polish group (P = 0.15). CONCLUSION: These results show a statistically significant difference in the number of high-risk Polish vs. non-Polish white patients with an increase rate of CRC in the Polish group although not statistically significant. These findings warrant larger population based studies to further investigate the benefit of earlier screening for these patients similar to African Americans.
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