The European Commission has developed a Real-Driving Emissions (RDE) test for road vehicles that complies with the urban, rural and motorway criteria to ensure the exhaust emission produced could be accurately evaluated. Therefore, careful measures are taken in selecting the best routes to ensure the testing fulfils the targeted criteria. As there is no common method exist to select the testing route, analysis on the testing route selection was implemented using Geographic Information System (GIS) platform that is capable to deal with large vector data. Thus, the proposed framework facilitates the testing route selection process which is difficult to determine without a proper spatial analysis of network data. Specific route information comprises of road categories, route speed range and route classes were collected from the Open StreetMap (OSM) database. The generated route density and the topological route network structure were used to further analyse the suitability route as the requirement of Real-Driving Emissions test. As a result, five candidates of Real-Driving Emissions test route have been selected in Malaysia as a case study using GIS platform.