PurposeThe purpose of the study is to examine gun violence prevention practices among urban police in the USA, assessing their scope, effectiveness, limitations, and impacts.Design/methodology/approachA national survey was conducted with police agencies serving cities of 100,000 or more people.FindingsStrategies used most frequently and rated as most effective include targeted efforts focussed on high‐risk places and groups, as well as multi‐agency problem‐solving efforts, particularly those involving federal authorities. However, most agencies make limited use of proactive strategies to reduce gun crime, and there are substantial gaps in the enforcement of many gun laws. Results also suggest that gun crime is lower in places where police engage in more intensive gun‐related enforcement and prevention efforts.Research limitations/implicationsThe survey focussed only on large US cities. Implementation of the strategies could not be examined in detail, and assessments of the effectiveness of strategies reflect the views of practitioners. There is a need for more in‐depth research on gun‐related enforcement and prevention practices, their effectiveness, and the organizational and environmental factors that facilitate or hinder them.Practical implicationsThe study highlights strategies that should be given priority consideration in policy decisions. The findings also suggest that police efforts to address gun crime can be enhanced considerably – and that doing so may produce demonstrable reductions in gun crime. Further examination of policy changes necessary to facilitate these efforts is warranted.Originality/valueThis study represents the first national survey of gun violence reduction efforts by police in the USA.