Direct-drive generators are recognised for their low maintenance compared with conventional drivetrains, largely due to their fewer working parts. However, consequent to low-speed operation, these machines necessitate large diameters and are subject to rigorous stiffness requirements. Significant internal and external forces influence structural integrity, so to design them efficiently, consideration of all operating parameters is imperative. Therefore, through Finite Element Analysis, this paper sets out to quantify the influence of each operating parameter on the integrity of a parametrically optimised rotor structure under established operating conditions and introduces operating temperature to the current models. An environmental impact analysis of the optimised rotor structure and cost analyses of both the optimised and unaltered structures are carried out simultaneous to the design process. We find the use of parameter optimisation alone to be insufficient for rotor structures of this scale due to high increased mass and costs of manufacture. A significant finding from this study is that the thermal effects on large-scale direct-drive generator structures may be vastly underestimated and have a much greater influence on structural integrity than first thought.