Large-scale Movements Research Articles

Common Murre (Uria aalge) die-off in the Kodiak Archipelago, Alaska, April 2015–April 2016

A mass die-off of Common Murres (Uria aalge) occurred from spring 2015 to spring 2016 in the northern Gulf of Alaska. Seabird die-offs have been recorded previously in the region, but this event was unique in its long duration and wide spatial extent. In response to the die-off, Kodiak National Wildlife Refuge (NWR) biologists conducted systematic beach surveys along the road system adjacent to the city of Kodiak and compiled reports from local citizens in remote locations throughout the Kodiak Archipelago to document the number of dead birds observed on beaches. Analysis of beached bird records indicated that at least 1,994 dead Common Murres were observed in the Kodiak Archipelago from 4 April 2015 to 26 April 2016. Extrapolating the density estimate, based on carcasses counted on systematic surveys on the Kodiak road system (55 murres/km, SE = 12), to all beaches in the Kodiak road system study region in the same biophysical habitat class based on Alaska ShoreZone coastal mapping, yielded an estimate of 6,305 dead Common Murres (95% CI = 3,522–9,088). In addition to Common Murres, carcasses of another 65 birds representing 15 species were found on beaches on the Kodiak road system during the die-off. The die-off event was preceded by a large-scale inshore movement by marine bird species typically seen offshore (Common Murres and shearwater species), as documented by Kodiak NWR survey data and by local observers throughout the archipelago. Survey data indicate the population estimate for Common Murres in the northeastern region of the archipelago increased from 711 in June 2012 to 31,543 in June 2015 (4,335% increase), and from 5,063 in August 2012 to 64,039 in August 2015 (1,165% increase).

The accuracy of several pose estimation methods for 3D joint centre localisation

Human movement researchers are often restricted to laboratory environments and data capture techniques that are time and/or resource intensive. Markerless pose estimation algorithms show great potential to facilitate large scale movement studies ‘in the wild’, i.e., outside of the constraints imposed by marker-based motion capture. However, the accuracy of such algorithms has not yet been fully evaluated. We computed 3D joint centre locations using several pre-trained deep-learning based pose estimation methods (OpenPose, AlphaPose, DeepLabCut) and compared to marker-based motion capture. Participants performed walking, running and jumping activities while marker-based motion capture data and multi-camera high speed images (200 Hz) were captured. The pose estimation algorithms were applied to 2D image data and 3D joint centre locations were reconstructed. Pose estimation derived joint centres demonstrated systematic differences at the hip and knee (~ 30–50 mm), most likely due to mislabeling of ground truth data in the training datasets. Where systematic differences were lower, e.g., the ankle, differences of 1–15 mm were observed depending on the activity. Markerless motion capture represents a highly promising emerging technology that could free movement scientists from laboratory environments but 3D joint centre locations are not yet consistently comparable to marker-based motion capture.

Six pelagic seabird species of the North Atlantic engage in a fly-and-forage strategy during their migratory movements

Bird migration is commonly defined as a seasonal movement between breeding and non-breeding grounds. It generally involves relatively straight and directed large-scale movements, with a latitudinal change, and specific daily activity patterns comprising less or no foraging and more traveling time. Our main objective was to describe how this general definition applies to seabirds. We investigated migration characteristics of 6 pelagic seabird species (little auk Alle alle, Atlantic puffin Fratercula arctica, common guillemot Uria aalge, Brünnich’s guillemot U. lomvia, black-legged kittiwake Rissa tridactyla and northern fulmars Fulmarus glacialis). We analysed an extensive geolocator positional and saltwater immersion dataset from 29 colonies in the North-East Atlantic and across several years (2008-2019). We used a novel method to identify active migration periods based on segmentation of time series of track characteristics (latitude, longitude, net-squared displacement). Additionally, we used the saltwater immersion data of geolocators to infer bird activity. We found that the 6 species had, on average, 3 to 4 migration periods and 2 to 3 distinct stationary areas during the non-breeding season. On average, seabirds spent the winter at lower latitudes than their breeding colonies and followed specific migration routes rather than non-directionally dispersing from their colonies. Differences in daily activity patterns were small between migratory and stationary periods, suggesting that all species continued to forage and rest while migrating, engaging in a ‘fly-and-forage’ migratory strategy. We thereby demonstrate the importance of habitats visited during seabird migrations as those that are not just flown over, but which may be important for re-fuelling.

Large-scale movement of eIF3 domains during translation initiation modulate start codon selection.

The eukaryotic initiation factor 3 (eIF3) complex is involved in every step of translation initiation, but there is limited understanding of its molecular functions. Here, we present a single particle electron cryomicroscopy (cryo-EM) reconstruction of yeast 48S ribosomal preinitiation complex (PIC) in an open conformation conducive to scanning, with core subunit eIF3b bound on the 40S interface near the decoding center in contact with the ternary complex eIF2·GTP·initiator tRNA. eIF3b is relocated together with eIF3i from their solvent interface locations observed in other PIC structures, with eIF3i lacking 40S contacts. Re-processing of micrographs of our previous 48S PIC in a closed state also suggests relocation of the entire eIF3b-3i-3g-3a-Cter module during the course of initiation. Genetic analysis indicates that high fidelity initiation depends on eIF3b interactions at the 40S subunit interface that promote the closed PIC conformation, or facilitate the relocation of eIF3b/eIF3i to the solvent interface, on start codon selection.

NONLINEAR DYNAMIC CHARACTERISTICS OF LUMBAR DISC SUBJECTED TO STOCHASTIC EXCITATION

The lumbar disc has complex structure and material properties, and if it develops disease, it cannot heal itself. Therefore, prevention of lumbar disc herniation is very important. In this paper, the model of lumbar disc is built, and the nonlinear dynamic response of the system is researched. A modified Van der Pol model is imported to describe the stress–strain curves of the lumbar disc. The system’s dynamic model is set up, and harmonic balance method is applied to revise the natural frequency of the system. The product of numerical simulation reveals that the lumbar disc has complex dynamic characteristics, including balance point, limit cycle bifurcation and stochastic Hopf bifurcation. By changing the parameters, we can avoid large-scale periodic movement of the lumbar disc which causes lumbar disc herniation. These results contribute to the prevention of lumbar disc herniation.

A New Rockfall Simulation Tool based on Unity 3D

Objectives: Rockfall occur frequently in the mountainous areas of Southwest China, causing huge casualties and property losses every year. A rapid simulation method of the collapse process is urgently needed. The commonly used collapse simulation software still has obvious shortcomings, such as low terrain accuracy, no consideration of the structural characteristics of rock mass, as well as block collision and fragmentation. The logic operation based on CPU still limits the calculation speed. In this study, a new method for rapid simulation of the three-dimensional motion process of collapse is proposed. Methods: The Unmanned aerial vehicle (UAV) aerial photography modelling combined with field investigation is used to obtain the slope surface model and determine the characteristic parameters of rockfall. The simulation software of a large-scale collapse movement process is developed by Unity 3D platform which integrates PhysX physics engine and CPU-GPU parallel computing capability. Results: The software can simulate the whole process of collapse, impact, fragmentation, and deposition. It can output the three-dimensional trajectory, velocity, energy and jumping height, which can be used for the engineering design. Finally, Xiejiayan rockfall in Nayong, Guizhou Province has been selected as an application case, to verify the feasibility and suitability in practice.

Strain maps characterize the symmetry of convergence and extension patterns during zebrafish gastrulation

During gastrulation of the zebrafish embryo, the cap of blastoderm cells organizes into the axial body plan of the embryo with left–right symmetry and head–tail, dorsal–ventral polarities. Our labs have been interested in the mechanics of early development and have investigated whether these large-scale cell movements can be described as tissue-level mechanical strain by a tectonics-based approach. The first step is to image the positions of all nuclei from mid-epiboly to early segmentation by digital sheet light microscopy, organize the surface of the embryo into multi-cell spherical domains, construct velocity fields from the movements of these domains and extract strain rate maps from the change in density of the domains. During gastrulation, tensile/expansive and compressive strains in the axial and equatorial directions are detected as anterior and posterior expansion along the anterior–posterior axis and medial–lateral compression across the dorsal–ventral axis and corresponds to the well characterized morphological movements of convergence and extension. Following gastrulation strain is represented by localized medial expansion at the onset of segmentation and anterior expansion at the onset of neurulation. In addition to linear strain, symmetric patterns of rotation/curl are first detected in the animal hemispheres at mid-epiboly and then the vegetal hemispheres by the end of gastrulation. In embryos treated with C59, a Wnt inhibitor that inhibits head and tail extension, the axial extension and vegetal curl are absent. By analysing the temporal sequence of large-scale movements, deformations across the embryo can be attributed to a combination of epiboly and dorsal convergence-extension.

Real-time monitoring of deformed wing virus-infected bee foraging behavior following histone deacetylase inhibitor treatment

SummaryImpairment in the learning/memory behavior of bees is responsible for the massive disappearance of bee populations and its consequent agricultural economic losses. Such impairment might be because of o both pesticide exposure and pathogen infection, with a key contributor deformed wing virus (DWV). The present study found that sodium butyrate (NaB) significantly increased survival and reversed the learning/memory impairment of DWV-infected bees. A next-generation sequencing analysis showed that NaB affected the expression of genes involved in glycolytic processes and memory formation, which were suppressed by DWV infection. In addition, we performed a large-scale movement tracking experiment by using a wireless sensor network-based automatic real-time monitoring system and confirmed that NaB could improve the homing ability of DWV-infected bees. In short, we demonstrated the mechanism of how epigenetic regulation can resume the memory function of honeybees and suggest strategies for applying NaB to reduce the incidence of colony losses.

Application research of urban subway traffic mode based on behavior entropy in the background of big data

With the development of society and the Internet and the advent of the cloud era, people began to pay attention to big data. The background of big data brings opportunities and challenges to the research of urban intelligent transportation networks. Urban transportation system is one of the important foundations for maintaining urban operation. The rapid development of the city has brought tremendous pressure on the traffic, and the congestion of urban traffic has restricted the healthy development of the city. Therefore, how to improve the urban transportation network model and improve transportation and transportation has become an urgent problem to be solved in urban development. Specific patterns hidden in large-scale crowd movements can be studied through transportation networks such as subway networks to explore urban subway transportation modes to support corresponding decisions in urban planning, transportation planning, public health, social networks, and so on. Research on urban subway traffic patterns is crucial. At the same time, a correct understanding of the behavior patterns and laws of residents’ travel is a key factor in solving urban traffic problems. Therefore, this paper takes the metro operation big data as the background, takes the passenger travel behavior in the urban subway transportation system as the research object, uses the behavior entropy to measure the human behavior, and actively explores the urban subway traffic mode based on the metro passenger behavior entropy in the context of big data. At the same time, the congestion degree of the subway station is analyzed, and the redundancy time optimization model of the subway train stop is established to improve the efficiency of the subway operation, so as to provide important and objective data and theoretical support for the traveler, planner and decision maker. Compared to the operation graph without redundant time, the total travel time optimization effect of passengers is 7.74%, and the waiting time optimization effect of passengers is 6.583%.

Large- and small-scale movement and distribution of acoustically tagged lake sturgeon (Acipenser fulvescens) in eastern Lake Erie

BackgroundDefining the spatial distribution, home range, and movement patterns of lake sturgeon (Acipenser fulvescens) is important to managers and decision-makers given the large migration potential and potamodromous behavior exhibited by the species. A remnant population of lake sturgeon remains in the far eastern basin of Lake Erie and although recent efforts have estimated the population size, described the age distribution, and identified a primary spawning site no study to date has examined the spatial distribution or movements of individuals within this population. Between 2014 and 2018, we acoustically tagged 59 adult lake sturgeon, captured in the Buffalo Harbor area, and monitored their large-scale movements throughout Lake Erie with the Great Lakes Acoustic Telemetry System and small-scale movements with a Vemco Positioning System in the Buffalo Harbor area. After dividing Lake Erie into seven sections, we ran a multi-state mark–recapture model to examine the movement rates into and out of the eastern most section of the lake. Within a heavily utilized lake section, in the Buffalo Harbor area, we identified home ranges with our Vemco Positioning System for each season and year using averaged Brownian bridge movement models.ResultsAlthough some sturgeon demonstrated large-scale movements, traversing the entirety of Lake Erie, the majority of individuals spent their time in the eastern basin of the lake. Home ranges appeared to vary among seasons, but were consistent across years with lake sturgeon selecting the northeastern, rocky, and shallow area of our array during pre-spawning and spawning seasons and leaving our array, or selecting a trough running along the northwestern portion of our array comprising sand and bedrock, in the summer and fall seasons.ConclusionsDocumenting these large-scale movements aligns with previous findings that lake sturgeon on either end of the lake are genetically similar and demonstrates lake sturgeon in the eastern basin exhibit strong philopatry. Our small-scale movement models provide managers with spatial reference points, in the form of utilization distributions, indicating heavily used areas by lake sturgeon within seasons. Future studies should examine what parameters are driving site selection in these areas.

Post-traumatic Growth in the First COVID Outbreak in Hong Kong

Post-traumatic growth (PTG) emerges from highly stressful situations. The coronavirus (COVID) pandemic may qualify as one. This study investigated the PTG among Hong Kong citizens during the first outbreak in spring 2020, shortly after a large-scale social movement subsided. A longitudinal online survey was launched during the peak (Time 1) and the palliation (Time 2) of the outbreak. Among the 327 participants who completed both waves, 28.4% exhibited probable post-traumatic stress disorder (PTSD) in Time 1, while 18.0% reported significant PTG in at least one domain in Time 2. The interaction between the sense of coherence (SOC) and post-traumatic stress mediated the relationship between Time 1 perceived outbreak severity and Time 2 PTG, such that PTG was more likely among participants with higher post-traumatic stress and SOC. PTG was also associated with a weaker contingency between Time 1 and Time 2 perceived outbreak severity. Echoing the transformational model, our findings show that both experienced stress and coping resources are essential for PTG to emerge. We also demonstrated how PTG might lead to more flexible risk perceptions according to the development of the outbreak.

Tick infestation of birds across a gradient of urbanization intensity in the United States Great Plains

Migratory birds play an important role in large-scale movements of ticks and tick-borne pathogens, yet little is known about tick infestation of resident birds (e.g., non-migratory species and migratory species during the breeding season), especially in urban ecosystems. We captured birds during the breeding season in parks and greenspaces in Oklahoma City, Oklahoma, USA, to evaluate overall tick infestation patterns and to determine if urbanization influences infestation prevalence (the proportion of birds parasitized) and intensity (the number of ticks on infested birds). Of 459 birds, 111 (24.2%) had ≥ 1 tick, a high proportion of infestation compared with past North American studies. The most frequently infested species were Carolina Wren (Thryothorus ludovicianus; 56%), Brown Thrasher (Toxostoma rufum; 37%), and Northern Cardinal (Cardinalis cardinalis; 27%). The Lone Star Tick (Amblyomma americanum) comprised half (51%; n = 322) of all ticks on birds; other species sampled included Gulf Coast Tick (A. maculatum) (36%) and Rabbit Tick (Haemaphysalis leporispalustris) (13%). Urbanization intensity (i.e., the percentage of developed land around sites) was inversely related to infestation prevalence for all birds combined and for Carolina Wren, but intensity of infestation was unrelated to urbanization. Our results suggest that non-migratory and migratory birds during sedentary periods are important carriers of ticks in urban areas, and that tick infestation patterns can be influenced by the level of urbanization in the surrounding landscape. Clarifying how urban birds influence tick populations, and how urbanization shapes bird-tick interactions, will increase understanding of tick-borne disease ecology in urban ecosystems.

Insights into the mutations leading to capreomycin resistance in S-adenosyl-L-methionine binding motif in TlyA from Mycobacterium tuberculosis

Capreomycin is a second line antibiotic used for the treatment of drug resistant Tuberculosis (TB), primary reason of death from a solo infectious organism, Mycobacterium tuberculosis (M.tb). Capreomycin targets the ribosome of bacteria and is known to bind at the interface where the large and small ribosomal subunits interact in M.tb using an S-Adenosyl Methionine (SAM) dependent methyltransferase, TlyA (Rv1794). Besides the methyltransferase activity, TlyA has also been found to show substantial haemolytic activity. The dual activity of TlyA highlights its crucial role in pathogenesis and virulence of M.tb. In the present study, docking and molecular dynamics (MD) simulations were carried out to explore the impact of mutations in a conserved SAM binding motif, 90GASTG94, on the affinity of TlyA enzyme for SAM. Two already reported mutations, A91E and S92L, and the remaining wild type residues, Gly90, Thr93, Gly94 mutated to alanine were taken into consideration resulting in a total of six systems, wild type + SAM, G90A + SAM, A91E + SAM, S92L + SAM, T93A + SAM and G94A + SAM that were subjected to 100 ns MD simulations. Docking scores and MD simulations analyses revealed that in contrast to wild type, mutants reduced the affinity of SAM for TlyA with most prominent effect observed in case of alanine mutants. Mutations also led to the loss of hydrogen bond and hydrophobic interactions and large-scale movement of atoms evident from the principal component analyses indicating their destabilizing impact on TlyA. The present study gives insights into influence of mutations on binding of SAM to TlyA in M.tb and promoting capreomycin resistance. Communicated by Ramaswamy H. Sarma

Features of the geological structure, tectonic development and oil and gas potential of the Chezhen depression (Bohai bay basin)

Background. In terms of oil and gas, the territory of the Chezhen depression has been studied insufficiently compared to the neighbouring same-range depressions. These depressions complicate the first-order Jiyang depression, geographically coinciding with the largest Shengli hydrocarbon field. In recent years, much geological and geophysical information about the oil geologyof the Chezhen depression has been accumulated, which allows its prospecting oil and gas potential to be assessed.Aim. To reveal regular features of the geological structure and location of oil deposits in the Chezhen depression in order to support the prospecting and exploration work within the Chezhen block of the Shengli field.Materials and methods. A comprehensive analysis of literature data and collected materials was conducted. A historical and geodynamic study of the evolution of the studied area according to literature data was carried out, along with an analysis of the most recent geological and geophysical information and exploration data based on the materials of the “Shengli AKOO Sinopek” oil company. The analysis was based on the data from 52 drilling wells and the results of seismic surveys performed in the central part of the Chezhen depression.Results. Specific features of the block geological structure of the area under study were established, which formed under the repeated influence of large-scale horizontal tectonic movements occurring at different periods of geological history. The role of the most recent fault system in the modern spatial distribution of oil deposits was determined.Conclusions. Our studies demonstrate a great prospecting potential of the Chezhen depression territory, where the discovery of new industrial oil deposits can be expected.

Research on Strong Ground Pressure of Multiple-Seam Caused by Remnant Room Pillars Undermining in Shallow Seams

Numerous room-and-pillar mining goaf are apparent in western China due to increasing small coal mining activities, which causes the collapse of the overlying coal pillars and the occurrence of strong ground pressure on the longwall face and surface subsidence. In this study, Yuanbao Bay Coal Mine, Shuozhou, Shanxi, was selected to study the collapse of the overlying coal pillars on the longwall face and reveal the mechanism of the pillar collapse and the disaster-causing mechanism caused by strong ground pressure. Results show that the dynamic collapse process of coal pillars is relatively complicated. First, the coal pillars on both sides of the goaf are destroyed and destabilized, followed by the adjacent coal pillars, which eventually cause a large-scale collapse of the coal pillars. This results in a large-scale cut-off movement of the overlying strata, and the large impact load that acts on the longwall face causes an unmovable longwall face support. Moreover, the roof weighting is severe when strong ground pressure occurs on the longwall face, causing local support jammed accidents. Furthermore, the data of each measurement point of the strata movement inside the ground borehole significantly increases, and the position of the borescope peeping error holes in the ground drill hole rise steeply. The range of movement of the overlying strata increases instantaneously, and the entire strata begin to move. Research on the mechanism of strong ground pressure can effectively prevent mine safety accidents and avoid huge economic losses.

Refugee Solidarity Along the Balkan Route

Abstract In 2015, the mass mobilities of refugees, many from Syria, towards Western Europe, were presented as a crisis threatening the integrity of nation-states. Whilst governments along the so-called ‘Balkan route’ increasingly responded with exclusionary measures, large-scale solidarity movements emerged and played a key role in assisting refugees in their journeys and settlement. All along the route, activists and volunteers (sometimes in loose collaboration with official relief organizations) established solidarity communities that tasked themselves with assisting people on the move. Their activities have been underpinned by discourses of solidarity and hospitality reflecting deep-seated popular beliefs about displacement, sanctuary and refuge—alternative narratives of what is today called asylum. Based on ethnographic fieldwork with solidarity and refugee groups in Greece, Serbia and Hungary, I examine the practices and discourses of refugees and those mobilized to support them along the ‘Balkan route’.

The Syrian Emergency: A Catalyst for Change in the International Refugee Regime

Abstract Beginning in 2012, the Syrian refugee exodus has been one of the largest, speediest, and geopolitically significant seen in recent years. It has placed enormous pressures on host states in the Middle East, stretched the international humanitarian system to breaking point, and, of course, entailed enormous suffering for the millions of Syrian citizens who have been forced to flee from their own country. At the same time, the Syrian crisis has had a much broader impact on the global refugee regime and the way in which the international community addresses large-scale movements of displaced people. This article explores that impact, focusing on issues such as encampment and settlement strategies, the use of cash transfers, refugee employment and livelihoods, the refugee impact on host communities, the engagement of development actors in humanitarian crises and the challenge of providing safe and legal routes to people in need of protection. In these respects, the article suggests, the Syrian refugee emergency has acted as a more important catalyst for change than the high-level diplomatic activity associated with the Global Compact on Refugees.

Pivoting to the QUAD AIM-Lessons Learned From the Central Texas Market.

ABSTRACTIntroductionSince 2009, the Military Health System (MHS) has represented its mission as that of attaining the Quadruple Aim (QUAD AIM): increased readiness, better health, better care, and low per capita costs. The journey to reach the four goals is challenging and ongoing. Leaders in the MHS’s Central Texas Market (CTM) sought to understand and overcome the root-cause obstacles that interfered with achieving the QUAD AIM. This process required a self-critical and thoroughly objective review of the behavioral economics of the system. We hypothesized that two corporate behaviors fed upon each other to create a vicious downward spiral. First, as a socialized (salary-based) system, the enterprise has a built-in incentive that covertly competes with the attainment of the QUAD AIM. Because additional work does not result in any material gain for its workers, the system regulates to a comfortable flow. Second, centralized leaders defer important management controls to tactical teammates due to their special medical expertise. This corporate behavior makes overcoming the first one challenging—keeping realization of the QUAD AIM elusive.MethodsBeginning in July of 2019, CTM leaders strove to replace the two identified corporate behaviors with more productive ones. First, in place of regulating to comfort, we directed teammates to focus wholly on achieving the QUAD AIM. Second, we exerted leadership from the top down to attain the QUAD AIM’s four goals. Because the vicious cycle manifested itself differently in the realms of primary, inpatient, and specialty care, we adapted the application of our virtuous behaviors to match the problem set in each realm. In primary care, we replaced fee-for-service incentives with value-based ones. In inpatient care, we eliminated hidden incentives that resulted in inappropriate and unnecessary transfers. In specialty care, we consolidated the management of referrals, templating, and scheduling—taking central control of system productivity. The interventions in each realm required the introduction of new workflows, policies, and dashboards to ensure change.ResultsOver a 2-year period, the CTM made a quantum to leap toward attaining the QUAD AIM. In our community based primary care homes, we significantly improved our operations as quantified by the value-based metrics of patient satisfaction, Healthcare Effectiveness Data and Information Set (HEDIS) quality metrics, access to care, and leakage. In the inpatient realm, we decreased monthly transfers by 73% (110 s to 30 s) resulting in higher bed censuses and multiple downstream positive impacts. In specialty care, we demonstrated our ability to return our specialty service lines quickly to high levels of production in the coronavirus disease-2019 crisis. Each of these interventions demonstrated large-scale movement toward the QUAD AIM.ConclusionsThe CTM’s actions demonstrate that the QUAD AIM can be attained in military medicine. Doing so requires the recognition of two destructive corporate behaviors. Through decades of hardening, these corporate behaviors have been imprinted upon the MHS, making them practically invisible as guiding currents in economic behavior. Counteracting them with persistent regulation to the QUAD AIM facilitated by proactive top-down leadership offers a solution.

Reducing the Cognitive Footprint of Brain Tumor Surgery.

The surgical management of brain tumors is based on the principle that the extent of resection improves patient outcomes. Traditionally, neurosurgeons have considered that lesions in “non-eloquent” cerebrum can be more aggressively surgically managed compared to lesions in “eloquent” regions with more known functional relevance. Furthermore, advancements in multimodal imaging technologies have improved our ability to extend the rate of resection while minimizing the risk of inducing new neurologic deficits, together referred to as the “onco-functional balance.” However, despite the common utilization of invasive techniques such as cortical mapping to identify eloquent tissue responsible for language and motor functions, glioma patients continue to present post-operatively with poor cognitive morbidity in higher-order functions. Such observations are likely related to the difficulty in interpreting the highly-dimensional information these technologies present to us regarding cognition in addition to our classically poor understanding of the functional and structural neuroanatomy underlying complex higher-order cognitive functions. Furthermore, reduction of the brain into isolated cortical regions without consideration of the complex, interacting brain networks which these regions function within to subserve higher-order cognition inherently prevents our successful navigation of true eloquent and non-eloquent cerebrum. Fortunately, recent large-scale movements in the neuroscience community, such as the Human Connectome Project (HCP), have provided updated neural data detailing the many intricate macroscopic connections between cortical regions which integrate and process the information underlying complex human behavior within a brain “connectome.” Connectomic data can provide us better maps on how to understand convoluted cortical and subcortical relationships between tumor and human cerebrum such that neurosurgeons can begin to make more informed decisions during surgery to maximize the onco-functional balance. However, connectome-based neurosurgery and related applications for neurorehabilitation are relatively nascent and require further work moving forward to optimize our ability to add highly valuable connectomic data to our surgical armamentarium. In this manuscript, we review four concepts with detailed examples which will help us better understand post-operative cognitive outcomes and provide a guide for how to utilize connectomics to reduce cognitive morbidity following cerebral surgery.

What's in a Name? Why it is of vital importance to get the pronunciation right?

Health services across the world are on the one hand the most regulated of all professions, the workforce planning is the most advanced and the restrictions on licence to practice most stringent, especially across borders- yet the workforce is dependent on the ability of large scale movement of professionals across nation-states. The UK NHS has over 41% of its doctors and a quarter of all nurses who were born / trained overseas. This is not much different to many other advanced health systems.
 It is also recognised that patient outcomes, recruitment and retention of healthcare professionals who are in great demand depends on autonomy, job satisfaction and a sense of value, equality and a just environment.
 A fundamental tenet of equality, celebrating diversity and inclusion is how organisation or society deals with the immigrant professionals or ‘foreigners’. The ability to correctly pronounce ‘foreign’ names is one of the fundamental and most obvious demonstration of respect one accords to a fellow human.
 There is a long standing practice of transfiguring foreign sounding names to anglicised or westernized versions for ease of use. The westernization of foreign names is predominantly imposed by the dominant segments of populations on those considered inferior. There is clear evidence of social inequalities linked to one’s race, ethnicity, immigration and gender. Transfiguring one’s name is a clear example of such discrimination, microaggression and a form of bias.
 It is time that we understood the impact of such microaggressions of colleagues and our patients. It should be vital for all professionals to take the time and attention needed to get the pronunciation right and in the process understand the cultural diversity, identity and demonstrate due respect and equality. It is also imperative on those of us with foreign sounding names that we help colleagues navigate the rich heritage of our culture and identity and do so with humility. It can only then be a win-win for all.