In the fields of geographic information systems and cartography, accurate topographic maps are crucial. Although traditional topographic mapping methods have certain accuracy, they have limitations in capturing features and building details. Therefore, this article proposes a large-scale 3D digital terrain mapping method based on oblique photography technology. Firstly, the UAV route is planned and image control points are arranged, to collect large-scale geographical object data by using UAV oblique photography technology. Then Smart 3D software is used to complete the 3D modeling of real large-scale topographic map through data preprocessing, air-to-air survey, control point import, 3D modeling, texture mapping and other steps based on the obtained geographical object data. The 2D and 3D linkage integrated mapping mode is adopted to obtain geomorphic information and elevation information, complete the data collection of indoor features, confirm the features that cannot be read on both sides of the indoor industry, complete the field supplementary mapping and adjustment, and realize the mapping of large-scale 3D digital topographic map. The experimental results show that this method can use oblique photography technology to collect data and establish a three-dimensional model of large-scale 3D digital terrain maps. The mean square error of accuracy detection is 0.202m, the mean square error of elevation is 0.257m, the mean square error of plane is 0.201m, and the mean square error of elevation is 0.197m. It has high drawing accuracy and excellent aerial triangulation performance.