Large-scale Centrifuge Research Articles

Failure Mechanism of Anti-Dip Layered Soft Rock Slope under Rainfall and Excavation Conditions

The phenomenon of toppling deformation and failure is common in slopes with anti-dip structures, especially in soft metamorphic rock slopes. This paper aims to explore the instability mechanism of anti-dip layered soft metamorphic rock landslides. Taking the slope of a mining area in the southern Qinling Mountains of China as a geological prototype, a large-scale centrifuge model test and a numerical simulation based on the combined finite and discrete element method (FDEM) were performed. The deformation and failure process, failure mode, and failure path of the slope under rainfall and excavation conditions were simulated. The results show that both the physical centrifuge model test and the new numerical model test can simulate the instability process of anti-dip layered soft metamorphic rock slopes, and the phenomena simulated by the two methods are also very close. Rainfall mainly weakens the mechanical properties of rock, while the excavation at the slope toe mainly changes the stress field distribution and provides space for slope deformation, both of which accelerate the instability of the anti-dip soft metamorphic rock slope. The failure process of an anti-dip layered soft rock slope can be described as follows: bending of the rock layer–tensile fracture along the layer–flexural toppling and cracking perpendicular to the rock layer–extension and penetration of the tensile fracture surface–sliding and instability of the slope.

Investigation of the block toppling evolution of a layered model slope by centrifuge test and discrete element modeling

Primary toppling usually occurs in layered rock slopes with large anti-dip angles. In this paper, the block toppling evolution was explored using a large-scale centrifuge system. Each block column in the layered model slope was made of cement mortar. Some artificial cracks perpendicular to the block column were prefabricated. Strain gages, displacement gages, and high-speed camera measurements were employed to monitor the deformation and failure processes of the model slope. The centrifuge test results show that the block toppling evolution can be divided into seven stages, i.e. layer compression, formation of major tensile crack, reverse bending of the block column, closure of major tensile crack, strong bending of the block column, formation of failure zone, and complete failure. Block toppling is characterized by sudden large deformation and occurs in stages. The wedge-shaped cracks in the model incline towards the slope. Experimental observations show that block toppling is mainly caused by bending failure rather than by shear failure. The tensile strength also plays a key factor in the evolution of block toppling. The simulation results from discrete element method (DEM) is in line with the testing results. Tensile stress exists at the backside of rock column during toppling deformation. Stress concentration results in the fragmented rock column and its degree is the most significant at the slope toe.

Numerical modeling of a pile-supported wharf subjected to liquefaction-induced lateral ground deformations

Fully-coupled nonlinear dynamic analysis is increasingly used for assessing the seismic performance of pile-supported wharf structures subjected to liquefaction-induced lateral ground deformations. Several numerical challenges exist for analysis of this highly nonlinear soil-structure interaction, which require robust, yet practical, solutions that are validated with experimental data. This study presents a numerical model of a pile-supported wharf and evaluates the applicability of a soil constitutive model, and modeling assumptions and methods by using recorded data from a well-instrumented, large-scale centrifuge test. The objectives of this study include: (a) evaluating the performance of a recently developed pressure-dependent multi-yield surface constitutive soil model (PDMY03) to simulate the behavior of a liquefiable sand (b) assessing the effectiveness of a soil–pile interaction modeling approach in capturing the kinematic displacement demands on piles from a laterally spreading ground, and (c) evaluating the effectiveness and limitations of the 2D numerical model in approximating the 3D behavior of a wharf structure supported by multiple rows of piles, including the dynamic response of the centrifuge container. The implications of these assumptions and lessons learned from this study provide guidance for researcher modelers and practitioners for numerical modeling of similar soil–structure systems.

NHERI Centrifuge Facility: Large-Scale Centrifuge Modeling in Geotechnical Research

Author(s): Boulanger, RW; Wilson, DW; Kutter, BL; DeJong, JT; Bronner, CE | Abstract: The 9-m and 1-m radius geotechnical centrifuges at the Natural Hazards Engineering Research Infrastructure (NHERI) facility at the University of California at Davis provide the national research community with open access to unique and versatile modeling capabilities for advancing methods to predict and improve the performance of soil and soil-structure systems affected by earthquake, wave, wind, and storm surge loadings. Large-scale centrifuge models are particularly effective for the building of basic science knowledge, the validation of advanced computational models from the component to the holistic system level, and the validation of innovative soil remediation strategies. The capabilities and unique role of large-scale centrifuge modeling are illustrated using three example research projects from the shared-use NHERI facility. Education impacts stemming from operations activities and coordination of activities by the center’s user base are discussed. Future directions and opportunities for research using the NHERI facilities are discussed.

Effect of Juice Turbidity and Yeast Lees Content on Brandy Base Wine and Unmatured Pot-still Brandy Quality

The aims of this project were to identify a suitable grape juice clarification technique for the attainment of the optimal brandy base wine turbidity, to determine the importance of chemical components (volatile components and long-chain fatty acids) in brandy base wine and unmatured pot-still brandy quality, and to study the effect of yeast lees content on quality. Although common industry practice is to use the grape cultivars Colombar(d) and Chenin blanc for the production of brandy base wine, the optimal conditions for Chenin blanc have been defined in this study. The juice clarification treatments applied included no settling, cold settling, whisk, large- and small-scale centrifugation and bentonite. Yeast strain 228 was compared with VIN13, large-scale (L) distillation was compared with small-scale (s) distillation, and the use of no enzyme was compared with the use of pectolytic enzyme. The data for four vintages were compiled and evaluated. Settling with or without pectolytic enzyme, bentonite, small-scale centrifugation and whisk treatments gave clearer Chenin blanc juice, higher concentrations of certain volatile components and long-chain fatty acids, and higher quality brandy base wine and unmatured pot-still brandy. No settling and large-scale centrifugation yielded the most turbid and lowest quality products. There is a definite relationship between treatments, turbidity, concentrations of esters, higher alcohols and acids, and overall brandy base wine and unmatured pot-still brandy quality. The use of yeast strain VIN13 (as opposed to strain 228), in conjunction with an increased yeast lees content of 1.5x that is normally found in brandy base wine, yielded the best quality unmatured pot-still brandy. Based on the results of this study, it is possible to recommend the best juice clarification method(s) for optimal turbidity as well as optimal levels of yeast lees addition, and to identify chemical compounds that positively relate to quality.

Large scale centrifuge test of a geomembrane-lined landfill subject to waste settlement and seismic loading

A large scale centrifuge test of a geomembrane-lined landfill subject to waste settlement and seismic loading was conducted to help validate a numerical model for performance based design of geomembrane liner systems. The test was conducted using the 240g-ton centrifuge at the University of California at Davis under the U.S. National Science Foundation Network for Earthquake Engineering Simulation Research (NEESR) program. A 0.05mm thin film membrane was used to model the liner. The waste was modeled using a peat-sand mixture. The side slope membrane was underlain by lubricated low density polyethylene to maximize the difference between the interface shear strength on the top and bottom of the geomembrane and the induced tension in it. Instrumentation included thin film strain gages to monitor geomembrane strains and accelerometers to monitor seismic excitation. The model was subjected to an input design motion intended to simulate strong ground motion from the 1994 Hyogo-ken Nanbu earthquake. Results indicate that downdrag waste settlement and seismic loading together, and possibly each phenomenon individually, can induce potentially damaging tensile strains in geomembrane liners. The data collected from this test is publically available and can be used to validate numerical models for the performance of geomembrane liner systems.

Centrifuge Testing of Model Levees atop Peat: Experimental Data

Four large-scale centrifuge tests were performed at the NEES@UCDavis equipment site to study the cyclic behavior of levee structures resting atop soft organic peat. The model configurations using a non-liquefiable levee focused on the seismic deformation potential of peat during primary consolidation and secondary compression. The tests performed with a sandy levee studied the liquefaction potential of saturated loose sand fill overlying soft peat as well as the levee-peat-interaction under different loading conditions. The models were subjected to scaled ground motions representative of the Sacramento/San Joaquin Delta. System instrumentation consisted of linear potentiometers, pore pressure sensors and accelerometers. Slow data recorded at 1 Hz document the settlements during spin up, application of ground motions, and spin down. Fast data sampled at 4,167 Hz measured the dynamic response of the system, the excess pore pressure increase and immediate settlements. The project is archived at the NEES data repository under nees.org/warehouse/project/1161 .

New Database for Foundation and Ground Performance in Liquefaction Experiments

Physical modeling of buildings founded on layers of liquefiable sand has produced insightful data describing ground and building performance. A new publicly available NEEShub database, “FLIQ,” summarizes data from 9 large-scale centrifuge tests with 4 different lead experimentalists, various soil profiles, 49 stations of site and structure response, and more than 60 shaking events, that is, 405 events in total. Example correlations between ground-motion intensity measures and performance measures are presented to illustrate the usefulness of the database. The relationship between PGA at the surface and base is highly variable when liquefaction is observed; however, the relationship between the cumulative absolute velocity ( CAV) at the surface and base is relatively linear, even when liquefaction occurs. Additionally, the CAV was found to correlate well with settlement and can account for settlement history. Contrary to intuition, foundation settlement in liquefied soil is not directly correlated to bearing pressure; larger bearing pressures can decrease liquefaction occurrence and related settlements. The database has potential to grow through future community input.

Experimental and Numerical Investigation of a Rayleigh-Bénard Convection Affected by Coriolis Force

In this paper the influence of an impressed Coriolis force field on the configuration of a turbulent Rayleigh-Benard convection problem is investigated in an experimental and numerical study. The main purpose of both studies lie on the analysis of a possible stabilising effect of a Coriolis acceleration on the turbulent unsteady structures inside the fluid. The relative Coriolis acceleration which is caused in the atmosphere by the earth rotation is realised in the experimental study by a uniform-rotational movement of the setup in a large-scale centrifuge under hyper-gravity. The same conditions as in the atmosphere in the beginning of a twister or hurricane should be realised in the experiment. The investigated Rayleigh numbers lie between 2.33 × 106 ≤ Ra ≤ 4.32 × 107.

An ultra scale‐down approach to assess the impact of the choice of recombinant P. pastoris strain on dewatering performance in centrifuges

Pichia pastoris is becoming a desirable host in the biopharmaceutical industry for therapeutics production. It grows on methanol to high cell densities ≥100 g DCW/L and secretes foreign proteins at high titers. However, the culture conditions to reach high cell densities pose a challenge to the processability by primary recovery operations, in particular centrifugation, used for cell removal. This work aims to assess the impact of recombinant P. pastoris strain selection on centrifugal dewatering. Normally, the choice of P. pastoris recombinant strain is based on best target protein expression levels; however, it is unknown whether the choice of strain will have an impact on performance of centrifugation operation. To achieve this aim, a previously developed laboratory ultra-scale down (USD) methodology that successfully predicted centrifugal dewatering of pilot-scale disk-type machines, was used in this work. Two recombinant P. pastoris strains, namely a X-33 and a glycoengineered Pichia strain, were used to perform fermentations secreting different products. The resulting harvested fermentation culture properties were analyzed and the dewatering performances of a pilot- and a large-scale disk-type centrifuge were evaluated using the USD methodology. The choice of P. pastoris strain was found to have a considerable impact on dewatering performance, with P. pastoris X-33 strain reaching better dewatering levels than the glycoengineered strain. The USD method proved to be a useful tool to determine optimal conditions under which the large scale centrifuge needed to be operated, reducing the need for repeated pilot-scale runs during early stages of process development for therapeutic products.

Ultra Scale‐Down To Define and Improve the Relationship between Flocculation and Disc‐Stack Centrifugation

The recovery of intracellular recombinant proteins produced in microbial systems typically requires physical, chemical or thermal treatment of the cells post-harvest to release the product into the broth, followed by removal of the cell debris using centrifugation or tangential flow filtration. Often a precipitation or flocculation step is introduced to facilitate the liquid-solid separation. Due to the complex nature of the cell materials and the unit operations, it is difficult to obtain data at laboratory scale that closely reflect the performance of these operations on larger scales (pilot or manufacturing). This study uses a predictive scale-down model that enables rapid optimization of the operating conditions for a flocculation followed with a centrifugation step using only small volumes (20 mL) of a high solids ( approximately 20% w/w) E. coli heat extract. Results obtained show that, with proper theoretical and experimental consideration to account for high cell density, conditions could be found that improve the beneficial interaction between flocculation and centrifugation. These experiments suggested that adding a higher level of a cationic polymer could substantially increase the strength of the flocculated particles produced, thereby enhancing overall clarification performance in a large scale centrifuge. This was subsequently validated at pilot scale.

Physical modelling of dynamic behavior of soil-foundation-superstructure systems

The goal of this paper is to promote the concept of testing centrifuge models that include soil-foundation-superstructure systems. Civil engineering research and practice is often compartmentalized, with structural engineers assuming very simplified foundation behavior, and geotechnical engineers assuming very simplified superstructure behavior. Only in rare cases does a bridge or building designer take account of energy dissipation through foundation yielding. Geotechnical engineers typically design foundations that meet minimum required capacity and stiffness specifications; they do not design foundations that optimize system performance. Large scale centrifuge models offer a unique capability to produce experimental data regarding seismic performance of soil-foundation-superstructure systems. In the centrifuge realistic models of buildings and bridge superstructures can be supported on realistic models of foundations with realistic soil behavior. Soil-foundation-superstructure systems have modes of behavior that are not present in experiments on individual foundation or superstructure components. Examples of two recent series of centrifuge tests demonstrate that system tests are possible and that unique data may be obtained. A spin-off benefit of soil-foundation-superstructure system model tests is the inevitable cross-disciplinary collaboration between structural and geotechnical engineers. It is suggested that this may eventually contribute to an evolution of design philosophy that is based more directly on system performance, with less focus on minimum component specifications.

Effects of Layer Thickness and Density on Settlement and Lateral Spreading

This paper presents the results of six large-scale centrifuge model tests that were performed to study the effect of relative density and thickness of sand layers on the amount of settlement and lateral spreading. The models included a “river” channel with clay flood banks underlain by layers of loose and dense sand of variable thickness, and a bridge abutment surcharge on one of the banks. The model container was tilted to provide an overall slope to the model. Each model was subjected to three or four significant ground motion events, which were obtained by scaling the amplitude of recordings of the Kobe (1995) and Loma Prieta (1989) earthquakes. Several measurements of acceleration, pore water pressure, settlement, and lateral movement are presented. The liquefaction potential index and a deformation index, which combine the influences of depth, density, and layer thickness, were found to correlate reasonably well with liquefaction induced settlements and lateral deformations for the range of models tested and indicate that centrifuge results are consistent with field observations.

Experimental Performance of a Seawall Model Under Seismic Conditions

Man-made islands have recently been considered as possible new construction sites for a variety of facilities. The performance of the seawalls bounding these islands when subjected to seismic loading is an important aspect of design. To obtain data on the performance of such structures when founded on a medium dense sand seabed and supported by an armored embankment, a series of large scale centrifuge models were tested at the University of California, Davis. The concrete caisson within the seawall was found to settle, displace laterally and rotate slightly away from the backfill. However, the deformations were limited, and global failure of the structure did not occur despite base accelerations of up to 0.6 g. The model accelerations were amplified up through the substratum and caisson during relatively small events, but were strongly attenuated during the larger events. Zones containing high excess pore pressures were generally located towards the top of the sand fill forming the island, and in the seabed below the toe of the armored embankment. These zones grew progressively larger as the event magnitude increased, and accordingly the times for pore pressure dissipation to occur lengthened with increasing event magnitude.

Settlement, Sliding, and Liquefaction Remediation of Layered Soil

A series of highly instrumented, large-scale centrifuge models have been tested to investigate the extent of remediation required to control settlement and lateral sliding of soil deposits at a hypothetical bridge site. The baseline model represents a prototype with a 9-m-thick layer of fine sand having a relative density (Dr) of 50%. The sand layer is overlain by clay floodplains with a free face at a river channel. One nearly level floodplain surface supports a bridge abutment. The other floodplain has a 9% slope toward the river. In different models, different amounts of the 50% relative density sand was densified to Dr = 80%. Full depth improvement reduced settlements and lateral sliding of the sand by about a factor of 3. Due to the effects at the clay-sand interface, lateral sliding of the surficial clay deposit was not controlled by densification of the sand. Tests in which the width of the densified zone was only about 75% of the thickness of the loose sand indicated that relatively narrow zones o...

High-resolution particle size analysis in biotechnology process control.

Many industrially important proteins can now be expressed intracellularly as insoluble protein inclusion bodies. In production, large-scale centrifugation is commonly used to separate and recover the inclusion bodies. Recovery efficiency depends critically on the centrifuge feed rate, which must be optimized to minimize production costs. We have used a disc centrifuge photosedimentometer to make high-resolution measurements of the particle size distribution (PSD) of the supernatant during the production of porcine somatotropin (pST) inclusion bodies. These measurements readily monitor the breakthrough of inclusion bodies into the supernatant and allow the centrifugation operation to be optimized.

Scale-up procedures for disc-stack centrifuges

Scale-up procedures have been obtained for geometrically similar disc-stack centrifuges using the recently computed liquid velocity profiles of Bohman. Grade-efficiency plots for a large-scale centrifuge can be obtained from experimental plots taken on a smaller unit by matching three dimensionless variables instead of only one as suggested by previous formulations.