CERN operated over the more than 50 years of its existence particle accelerators and storage rings ranging from a few tens of metre to 27 km, the size of its latest project, the Large Hadron Collider (LHC) which is under construction and will be started in 2008. The challenges began with the Intersection Storage Rings (ISR) in the seventies. With a beam pipe length of 2 × 1 km, this accelerator required innovative solutions like bake-out and glow discharge to achieve the required static vacuum level, fight against beam-induced pressure increases and cancel beam neutralisation by trapped electrons. The vacuum system of the Large Electron Positron (LEP) storage ring (in operation between 1989 and 2001) of a total length of 27 km had to cope with very high levels of synchrotron power. The beam vacuum system of LHC (2 × 27 km) integrates some parts at 1.9 K and others at room temperature and will also have to cope with dynamic effects. In addition to the beam vacuum system, LHC requires insulation vacuum for the superconducting magnets and the helium distribution line. Whereas the required pressure is not very low, the leak detection and localisation is significantly more demanding for the insulation vacuum than for the beam vacuum because of the large volumes and the thermal insulation.When the size of an accelerator grows, the difficulties are not only to get a clean and leak tight vacuum system, but also to be able to measure reliably pressure or gas composition over long distances. Furthermore, in the case of LHC the integration of the beam vacuum system was particularly difficult because of the complexity induced by a superconducting magnet scheme and the reduced space available for the beam pipes. Planning and logistics aspects during installation, including the usage of mobile pumping and diagnostic means, were much more difficult to manage in LHC than in previous projects.