Large Diameter Research Articles

Study on low temperature and narrow heating bands of post weld heat treatment for girth welds stress reduction of long-distance pipelines

Residual stress affects the service safety of pipelines, but there are few efficient methods to reduce the residual stress, especially for long-distance pipelines with large diameters. In this paper, a Secondary Post Weld Heat Treatment (S-PWHT) stress reduction method with low temperature and two narrow heating bands is proposed, and this method fully considers the failure of the corrosion resistance layer caused by high temperature. The temperature distribution and stress distribution under different S-PWHT parameters are compared to obtain the optimal S-PWHT parameters using finite element numerical simulation. The thermocouples are conducted to verify the temperature, and the coercivity experiment is used to verify the stress distribution. Results show that two heating bands width of 80 mm and a peak temperature of 120°C are the optimal S-PWHT parameters with the stress reduced by 61%. Besides, the levels of stress reduction on the inner surface and the HAZ are higher than those on the outer surface and the base metal, respectively. The high-stress zone is transferred from the inner surface to the outer surface, and from the HAZ to the base metal. Furthermore, the stress reduction mechanism of S-PWHT has been revealed through constraint theory. Temperature change is the initial force, and the constraint is the driving force for stress reduction.

Monitoring of GFRP pipelines in Power Plants using acoustic emission testing

In coal-fired power plants, the flue gas is transported through fibreglassreinforced pipelines to cooling towers during the combustion of the respective raw material, which often serve as a marker for a power plant in the landscape. These glass-fibre reinforced pipelines are located at great heights and can have very large diameters. Up to now, testing has been carried out as part of inspections during planned shutdowns and is associated with corresponding costs. The article discusses the use of acoustic measurement methods based on a 4-month installation at the Niederaußem power plant. Measurement results based on the acoustic emission analysis were shown. For the acoustic emission measurements, a repaired site was instrumented and different parameters like hit/event rates, acoustic energies as well as weighted peak frequencies of the acoustic signals were recorded over the monitoring period of 4 months at power plant Niederaußem. In a second power plant Neurath a 5-month AE monitoring were carried out. This measurement results were discussed as well.

Growth of copper single crystal using cone die Czochralski method

Copper (Cu) and other metal single crystals are useful as substrates for the deposition of atomic layer materials for many electronic applications, but the growth of large-sized single crystals is difficult to achieve. Characteristics of the metal material, namely seed elongation and intense cooling radiation at high temperatures during crystal growth, are the main challenges encountered when growing ingots with large diameters. These problems can be resolved by optimizing the crystal growth parameters. By adjusting the shoulder formation angle of the ingot shape to approximately 20° to 40°, we are able to grow a large (1-inch diameter, 30 mm length) single crystal of metal Cu using the Czochralski (CZ) method. However, the generation of suspended solids and film impurities such as reactants and precipitates and their nucleation, growth, and solidification, limited the further increase in size of the Cu crystal. Using the cone-shape die CZ (CD-CZ) method solves this problem and a 2-inch diameter Cu single crystal is successfully grown. This is the world’s largest single crystal metal grown using this method and it paves the way for the growth of other metal crystals.

Reconsidering assumptions in the analysis of muscle fibre cross-sectional area.

Cross-sectional area (CSA) is a fundamental variable in characterizing muscle mechanical properties. Typically, the CSA of a single muscle fibre is assessed by measuring either one or two diameters, and assuming the cross-section is either circular or elliptical in shape. However, fibre cross-sections have irregular shapes. The accuracy and precision of CSAs determined using circular and elliptical shape assumptions are unclear for mammalian skinned muscle fibres. Second harmonic generation imaging of skinned rabbit soleus fibres revealed that the circular assumption overstated real CSA by 5.3±25.9% whereas the elliptical assumption overstated real CSA by 2.8±6.9%. A preferred rotational alignment can bias the circular assumption, as real CSA was overstated by 22.1±24.8% when using the larger fibre diameter and understated by 11.4±13% when using the smaller fibre diameter. With 73% lower variable error and reduced bias, the elliptical assumption is superior to the circular assumption when assessing the CSA of skinned mammalian fibres.

A novel BCC-L21-BCC hierarchical heterostructure high entropy alloy with excellent corrosion resistance and mechanical properties in as-cast state

In this paper, a novel as-cast CrFeNiAl0.35Si0.1Ti0.1 high entropy alloy (HEA) with micron-to-nano hierarchical heterostructure was designed, and its microstructure, mechanical properties and corrosion resistance have been systematically investigated. It is found that, this novel HEA exhibits well-dispersed L21 phases with various sizes from micron-scale to nano-scale in the BCC matrix, while nano-sized BCC lamellas could also emerge in the L21 phase with large diameter. Moreover, this HEA exhibits not only excellent corrosion resistance in 3.5 wt.% NaCl solution that close to super-stainless steels, but also high mechanical properties combining yield strength of 1712±56 MPa, compressive plasticity of 21.2%±0.5% and hardness of ∼560 Hv. Such outstanding comprehensive properties for this HEA are possibly resulted from the complex hierarchical BCC-L21-BCC heterostructure with stable passive film and low diversity in work function between different phases. This work provides a novel route in the development of high-performance corrosion-resistant HEAs for structural and coating applications.

Shape-sensing Robotic-assisted Bronchoscopy (SS-RAB) in Sampling Peripheral Pulmonary Nodules: A Prospective, Multicenter Clinical Feasibility Study in China.

The ION system is a shape-sensing robotic-assisted bronchoscopy (SS-RAB) platform developed to biopsy peripheral pulmonary nodules (PPNs). There is a lack of data describing the use of this system in the Chinese population. The study aimed to assess the feasibility and safety of using SS-RAB to diagnose PPNs across multiple centers within China. This prospective, multicenter study used SS-RAB in consecutive patients with solid or sub-solid PPNs 8 to 30mm in largest diameter. Primary endpoints were diagnostic yield and the rates of procedure- or device-related complications. Radial endobronchial ultrasound (rEBUS) was to confirm lesion localization, followed by sampling, using the Flexision biopsy needle, biopsy forceps, and cytology brush. Subjects with nonmalignant index biopsy results were followed up to 6 months. A total of 90 PPNs were biopsied from 90 subjects across 3 centers using SS-RAB. The median nodule size was 19.4mm (IQR: 19.3, 24.6) in the largest dimension. In all (100%) cases, the catheter successfully reached the target nodule with tissue samples obtained. The diagnostic yield was 87.8% with a sensitivity for malignancy of 87.7% (71/81). In a univariate analysis, nodule lobar location, presence of bronchus sign, and rEBUS view were associated with a diagnostic sample, but only rEBUS view showed an association in a multivariate analysis. The overall pneumothorax rate was 1.1% without pneumothorax requiring intervention, and there was no periprocedural bleeding. As an emerging technology in the Chinese population, SS-RAB can safely biopsy PPNs with strong diagnostic performance.

Experimental study of oil-water two-phase flow patterns in a vertical large diameter pipe

The flow structure and the phase inversion have great influence on the flow measurement in vertical upward oil-water two-phase flow. This paper attempts to investigate the flow patterns in oil-water flows through a vertical upward large pipe with the designed mini-conductance array probes measurement system and the vertical multi-electrode array (VMEA) measurement system. According to the output waveform of the mini-conductance array probes, the oil-in-water flow, transition flow and water-in-oil flow can be identified effectively. The fluctuating signals of the VMEA is processed by the recurrence plot and the time-frequency representation, the results show that the VMEA conductance signal with average measurement characteristics can realize an effective identification of the above three flow patterns, which has a good agreement with the results of the mini-conductance array probes. Finally, via comparing with previous published flow pattern transition boundary models in different pipe diameters, it is founded that the boundary line of the transition to oil-in-water based on the kinematic wave-based model and the observation-based model in the same diameter pipe are consistent with our experimental data. And the pipe diameter affects the flow pattern transition, compared with the boundary in small diameter pipe, the phase inversion requires a larger oil velocity, and the transition zone becomes narrower in large diameter pipe.

Can lung anatomy predict the development of COVID-19 pneumonia in RT-PCR positive cases?

Purpose: The objective of this study was to investigate the relationship between Coronavirus disease 2019 (COVID-19) pneumonia and anatomical characteristics, including tracheobronchial and fissure variations, right/left main bronchus angle, carina angle, and large airway diameter, in patients who tested positive for the virus via reverse transcription-polymerase chain reaction (RT-PCR) at the outset of the pandemic. Materials and Methods: This cross-sectional study included 165 cases with positive RT-PCR tests who were admitted between March and June 2020 and subsequently scanned with thin-section unenhanced chest computed tomography (CT). They were divided into two groups according to the presence of pneumonia based on the chest CT images. Results: In our study, a total of 165 cases were analyzed, pneumonia was found in 35 of 76 (46.05%) female patients and 51 of 89 (57.30%) male patients. COVID-19 pneumonia was observed in older age groups. Anatomical variations and the presence of incomplete fissures were statistically higher in the pneumonia-positive group, while the difference was not statistically significant for accessory fissures. Mean tracheal area and right main bronchus angle were statistically higher in the pneumonia-positive group compared to the negative patients. The right lung was more involved than the left in terms of both zonal and total lung involvement. When the presence of comorbidity was assessed, 59 patients (35.75%) were found to have comorbidity. Hypertension, diabetes mellitus and cardiovascular disease were significantly higher among comorbidities in the pneumonia-positive group. The regression model showed that hypertension was associated with a 3.75-fold increase in COVID-19 pneumonia in test positive cases. Conclusion: Anatomical lung variations and incomplete fissures were observed more frequently in the COVID-19 pneumonia cases, independent of other comorbidities. We believe that there are anatomical variables that can be used to identify those predisposed to pneumonia in RT-PCR test positive cases.

Image processing and neural network technique for size characterization of gravel particles

Particle size is considered one of the significant characteristics used in geotechnical practices. Traditionally, sieve analysis is utilized for coarse-grained soil. However, this method could be time consuming and take much effort, especially for large scale infrastructure projects. This paper presents an efficient method for estimating gravel particle characterization utilizing image processing and artificial neural network technique (IPNN). The proposed algorithm is performed by utilizing particle boundary delineation and shape feature extraction to train a neural network model for estimating gravel size distribution curve. It is found that excellent agreement exists between the results obtained from conventional sieve analysis and neural analysis for gravel soil particles with maximum difference in passing percentages up to only 3.70%. The proposed technique shows satisfactory results for crushed stone samples with maximum difference in passing percentages about 10.90% mainly in large diameter particles. The presented technique (IPNN) could offer a promising alternative technique for material quality control process especially in large scale projects.

Distant metastasis patterns among lung cancer subtypes and impact of primary tumor resection on survival in metastatic lung cancer using SEER database.

This research aimed to systematically uncover the metastatic characteristics and survival rates of lung cancer subtypes and to evaluate the impact of surgery at the primary tumor site on cancer-specific survival in DM lung cancer. We used the Surveillance, Epidemiology, and End Results (SEER) database (2010-2019) to identify primary lung cancers with DM at presentation (M1). Kaplan-Meier (KM) survival curves were generated and compared utilizing log-rank tests. Cox regression methods were employed to determine hazard ratios (HR) and 95% confidence intervals related to CSS factors. Inverse probability of treatment weighting (IPTW) was applied to reduce bias. We analyzed 77,827 M1 lung cancer cases, with 41.22% having DM at presentation. Bone metastasis was most common in ADC, ASC, SCC, LCC; brain in LCNEC; liver in SCLC. Lung was common in TC + AC and SCC. Long-term survival was best in TC + AC and worst in SCLC (p < 0.001). Male gender, age < 50, primary tumor site (main bronchus, lower lobe), large tumor diameter, ADC/SCLC/SCC pathology, and regional lymph node involvement were significant risk factors for multiorgan metastasis. Age ≥ 50, male, large tumor diameter, positive lymph nodes, and multiorgan metastases were associated with lower CSS. In contrast, radiotherapy, chemotherapy, systemic therapy, and surgery were associated with higher CSS rates. Primary tumor resection improved survival in lung cancer patients (excluding small cell lung cancer, SCLC) with single organ metastases (KM log rank p < 0.001, HR = 0.6165; 95% CI (0.5468-0.6951)), especially in brain (p < 0.001, HR = 0.6467; 95% CI (0.5505-0.7596)) and bone (p = 0.182, HR = 0.6289; p < 0.01), but not in liver or intrapulmonary metastases after IPTW. Significant differences in DM patterns and corresponding survival rates exist among lung cancer subtypes. Primary tumor resection improves survival in lung cancer patients (excluding small cell lung cancer, SCLC) with single organ metastases, with better outcomes in patients with brain and bone metastases, while no significant benefit was seen in patients with liver and intrapulmonary metastases.

Numerical and experimental investigations on influence of spherical hinge mandrel on deformation characteristics of large diameter tube in small-radius NC rotary bending

Numerical and experimental investigations on influence of spherical hinge mandrel on deformation characteristics of large diameter tube in small-radius NC rotary bending

Self-Assembled Synthesis of Graphene Tubes from Melamine Catalyzed by Calcium Carbonate

This study investigates the carbon products generated by melamine under various heat-treatment temperatures with the catalysis of calcium carbonate. We discovered that the cost-effective precursor melamine readily self-assembles and curls into graphene tubes when catalyzed by the alkaline earth salt CaCO3 at elevated temperatures. Under heat-treatment conditions of 1100 °C and 1200 °C, the growth morphology of graphene tubes with open structures and exceptionally large diameters was observed, and the diameters reached the micron level. These products exhibit a high degree of carbonization and an extremely low nitrogen content, as low as 1.7%. Further, the intensity ratio (ID/IG) of the D band and the G band is as low as 0.79 in Raman characterization. The results show that the products have a certain graphite structure, which proves the catalytic activity of CaCO3. This is attributed to the incorporation of CaCO3 into the raw material system, which impedes the complete thermal decomposition of melamine. On the other hand, the resulting CaO particles are evenly distributed along the tubular products, providing certain support for their self-assembly and growth, thereby achieving the efficient growth of graphene tubes.

Critical diameter for a single-tank molten salt storage – Parametric study on structural tank design

Molten salt thermal energy storage (TES) is a cost-effective option for grid-connected storage in both concentrating solar power (CSP) plants and retrofitted thermal power plants in a multimegawatt scale. Current systems use two tanks (hot and cold), but future systems may use a single tank with a transient temperature profile (hot in the top and cold in the bottom) to reduce costs and space. However, the structural and mechanical design of large-scale molten salt single-tank storages at 560 °C has not been fully explored, and the impact of increasing the operating temperature to 620 °C is still uncertain. The challenge presented by a single tank is the existence of a temperature profile that results in a varying thermal expansion of the tank shell along its height. In the case of larger tanks, this discrepancy can reach a magnitude of centimeters, which in turn gives rise to bending moments. To the best of our knowledge, this study addresses the issue of bending stresses in large-sized high-temperature tanks with thermal stratification for the first time. The modelling approach is applied to single-tank CSP TES systems as a case study to evaluate the constraints imposed by tank size and wall thickness.With the help of experimentally validated numerical methods, it is revealed that a low thermocline thickness can be a limiting factor for large tank diameters. It is shown that the temperature has a major influence on maximum possible tank size: if the operating temperature is raised from 560 °C to 620 °C, the permitted tank diameter is significantly reduced when using the same tank wall material. A possible approach is to use a more heat resistant steel for 620 °C. Results of the parametric study show that designing a single tank below a critical diameter only requires a moderate increase of the wall thickness compared to the two-tank system with constant temperature profiles. Based on this parametric study a formula for the critical tank diameter is developed and presented in this work. The paper concludes with recommendations on how increased wall stresses can be addressed by an appropriate design.

Experimental study of two-phase pressure-drop in horizontal return bends with ammonia

In evaporators and condensers of refrigeration and air conditioning systems, various straight tubes are joined via U-bends. These U-bends result in higher pressure drops due to flow disturbances and centrifugal effects. Accurate prediction of pressure drops in these bends is essential for reliable design and operation. This study investigates the two-phase flow pressure-drop in horizontal U-bends with ammonia under wide range of experimental conditions. Three pipes with nominal outer diameter between 22.2, 15.9, and 9.5 mm were used, each with three bend radii (R/do ratio) between 1.2 and 2.5 in horizontal configuration. Tests were conducted at saturation temperature of +10 and -15 °C, with mass flux varying between 10 and 50 kg m−2 s−1, and vapor quality between 0.1 and 0.9. The pressure-drop increased with mass flux and vapor quality while decreased with saturation temperature, pipe diameter and R/do ratio of the bend.Large tubes exhibited a greater increase in pressure drop with rising mass flux and decreasing bend ratio compared to small tubes, which showed higher absolute values and more consistent performance across the vapor quality range at both saturation temperatures. The tube diameter had a less significant effect at high saturation temperature and high mass flux, while the bend curvature ratio predominantly influenced the pressure drop performance for large diameter tubes. One correlation from the literature predicted the data well only if the vapor quality was below 0.5. For wider range of quality, the existing models in the literature were not well-suited for predicting pressure drops in ammonia U-bends.

Strangler fig–host tree associations: Insights into the ecology and management of tropical urban green spaces

Societal Impact StatementThe strangler fig is known for its hemiepiphytic growth form and conspicuous strangling behavior in the tropics worldwide. It also plays an important role in providing ecological functions in tropical urban ecosystems. This study reveals strangler figs tend to colonize large trees with suitable microsites in a large tropical botanical garden and cause some negative effects on their hosts. We advocate balanced management strategies considering ecological functions, potential risks, and overall values of stranglers and their hosts. These results provide a scientific basis for us to develop better practices for plant management in urban green spaces (especially botanical gardens with high plant biodiversity) in tropical urban ecosystems.Summary Strangler figs colonize trees in tropical cities, which contribute to a unique urban ecology and enrich local ecological functions. Understanding ecological associations between strangler figs and their host trees can improve green space management in tropical urban ecosystems. We investigated 9282 trees growing in the Xishuangbanna Tropical Botanical Garden and then analyzed the diversity, characteristics, and network of strangler figs and their host trees. We found 13 strangler fig species (319 individuals) widely colonized 67 host species, with palm hosts bearing 52% of all strangler individuals. Strangler figs had a high colonization rate in large trees with appropriate microsites (e.g., persistent palm petioles and the fork of mature trees with rough trunks). Leaf nitrogen and phosphorus content of hosts decreased significantly after strangler figs' aerial roots had entered the ground. The strangler–host network was characterized by relatively high specialization and low nestedness, and simulated management of strangler figs on large hosts and palm hosts could simplify the strangler–host network. Strangler fig colonization can be managed. Planting trees with large diameters at breast height and rough bark can increase the colonization of stranglers, while cutting off aerial roots can inhibit their establishment. The epiphytic stage is the best time to manage strangler figs. We recommend taking into consideration the trade‐offs among ecological functioning, human safety, and the multifaceted value of strangler figs and their host trees and thereby implementing comprehensive management strategies tailored to different contexts for improving green space management in the tropics.

A multi-objective method for large multi-lane roundabout design through microscopic traffic simulation and SSAM analysis

Urban traffic congestion poses a significant challenge, impacting both economic efficiency and environmental sustainability. Roundabouts, recognized for their ability to improve traffic flow and reduce collisions, have become a focal point in traffic management strategies in urban areas. Different types and sizes of single and multi-lane roundabouts can be used, including conventional and innovative roundabouts with small, medium or large size diameters. Many optimization models are available for designing conventional roundabouts but not large roundabouts. To partially cover this gap, the present paper introduces a novel approach integrating simulation-based analysis with a goal programming method to optimize large roundabout design. By leveraging advanced traffic simulation tools like AIMSUN Next and Surrogate Safety Assessment Models (SSAMs), this methodology evaluates multiple design scenarios to enhance traffic flow, safety, and environmental performance. A case study of a complex large roundabout in the Italian greenest and sustainable city demonstrates the efficacy of this methodological approach. The findings provide valuable insights for traffic and highway engineers, emphasizing a data-driven, holistic approach to sustainable traffic management and roundabout optimization.

Case Report: Emergency endovascular management of a ruptured giant abdominal aortic aneurysm with severely angulated and conical shaped neck using novel multiple stiff wire technique

Background Ruptured abdominal aortic aneurysm (rAAA) is commonly fatal, with an overall mortality rate of nearly 90%, and the risk of subsequent rupture remains high, especially in large aneurysm diameters or progressive disease. Unfavorable neck anatomy in EVAR is linked to early graft failure and long-term complications. Recently, a novel multiple stiff wire (MSW) technique has been developed to overcome the challenges of hostile neck anatomy without introducing additional devices and procedural complexity. It has also been feasible in a series of elective cases. In this case, we report the first-ever utilization of the MSW technique in an emergency case of an acute contained rAAA with a conical-shaped, severely angulated neck who underwent Endovascular Aortic Repair (EVAR). Case presentation A 61-year-old man came with intermittent sharp stomach pain radiating to his back since three weeks ago. Physical examination showed elevated blood pressure and anemic conjunctiva. Laboratory examinations showed anemia, leukocytosis, elevated D-dimer level, high creatinine level, and low eGFR. CT-Scan Angiography (CTA) revealed severely hostile anatomy, a conical-shaped abdominal aorta aneurysm with a length of 13.2 cm and a maximum diameter of 9.3 cm with angulation of 90.1°. The patient was diagnosed with Ruptured AAA with a conical-shaped, severely angulated neck. Endovascular Aortic Repair (EVAR) management with MSW technique was planned for him. After four days, The patient was discharged in a clinically stable condition with optimal medical treatment and education. Conclusion The endovascular approach could be performed in emergency settings and has been proven to reduce length of stay, mortality, and morbidity rates. In this case, the endovascular approach with the MSW technique showed promising results for the patient.

Thin-walled FRP-concrete-steel tubular tower with a top mass block subjected to lateral impact loading: Experimental study and FE analysis

Thin-walled hollow steel tube towers (HSTs), frequently utilized as a wind turbine tower, are facing challenges such as corrosion and local buckling in their service life. To enhance the anti-corrosion capacity and local buckling resistance, an FRP tube and an annular concrete layer can be employed to protect the HST, thus forming a novel member: thin-walled FRP-concrete-steel tubular towers (TW-FCSTs). Using a horizontal vehicle impact system, this study investigated the impact behavior of five large-scale TW-FCSTs, each with a top mass block to mimic the rotor and nacelle of wind turbine. All specimens were designed with a large diameter (300 mm) and a large void ratio (0.73 or 0.82). The experimental results revealed that: (1) Under lateral impact loading, TW-FCSTs displayed a global flexural failure mode, accompanied by localized concavity damage; (2) The inertial effect was enlarged by the top mass block, affecting the dynamic response of TW-FCSTs; (3) the increase of steel thickness led to higher energy dissipation but lower local deformation; (4) the increase of void ratio resulted in larger local deformation but smaller lateral global displacement. Finally, based on LS-DYNA, FE models were utilized to simulate the dynamic responses of TW-FCSTs with a top mass block.

Cellulase gene expression in the thermophilic Thermomyces lanuginosus isolated from compost

Thermophilic fungi are superlative microorganisms for enzyme production, especially cellulase, and their using in biotechnological applications is due to their stability at utmost temperatures. In the current investigation, we isolated six genera encompassing six fungal species and one species variety from 30 samples of compost at 45 °C and 55 °C. Thermomyces lanuginosus was the most rampant species. The colony diameter of T. lanuginosus ranged from 2.8 to 4.3 cm at 45 °C on yeast-starch agar (YpSs) medium with white or greyish-brown mycelia. Fifteen isolates of T. lanuginosus were cellulase producers with variable competencies with a C/Z range of 1.09–1.38 cm. Fascinatingly, the clear zone diameter was much bigger when using Iodine than those obtained using Congo red. T. lanuginosus isolate no. 33 produced substantial amounts of cellulase on the four used media: Corncob (CC), Corncob treated with NaOH (C-NA), Yeast Peptone Dextrose (YPD), and CarboxyMethyl Cellulose (CMC) with the highest activity on CC; 143.9 μg/min, also cellulase gene expression levels of cel6Aq, cel7Aq, and bgl3Aq genes exhibited higher fold changes in the CC condition (7.26-fold, 11.51-fold, and 3.39-fold, respectively). X-ray fluorescence (XRF) analysis revealed the presence of 11 minerals with higher concentrations in CC than in C-NA. Supplementation of corncob medium with rosemary essential oil (CR) completely inhibited cellulase production. It adversely affected the growth, and changes in conidia, which were depicted using a scanning electron microscope (SEM). Interestingly, the conidia appeared much bigger than other media, and the large conidia diameter was 10.2–12.1 μm.

Rapid assessment of seismic performance of large monopile-supported offshore wind turbines under scour

This study focuses on investigating the seismic performance of a reference 15 MW offshore wind turbine (OWT) supported by a large-diameter monopile, under various scour conditions. Fully coupled nonlinear finite element models considering 3D soil continuum for seismic response analysis of monopile-supported OWTs are very complicated and computationally expensive. Therefore, it is important to have good insight on the dynamic behaviour of monopile-supported OWTs subjected to earthquake excitations before performing high-fidelity fully nonlinear 3D simulations, which will not generally be practical in cases considering various seismic loading and scouring scenarios. The purpose of this study is to provide a fast and efficient tool to understand the interaction between the seismic behaviour of emerging large-capacity OWTs when scour erosion affects the dynamic properties of the structure. The dynamic stiffness method (DSM) is applied for the free vibration analysis of the structure. Modal superposition is used to calculate the seismic responses of the OWT by using the exact mode shapes obtained from the dynamic stiffness formulations. The rotor-nacelle-assembly (RNA) is idealized as a lumped mass at the tower top. The tower and monopile are modelled as Timoshenko beam-columns under axial compressive loading. The soil-structure interaction (SSI) is modelled using the Winkler framework, whereby the soil contribution is assumed as elastic to take advantage of the modal superposition method. Two different approaches are considered for the soil stiffness; a constant profile, and a linearly-varying subgrade modulus along the embedded depth of the pile, and both are appraised in this paper. Firstly, natural frequencies obtained from dynamic stiffness formulations are validated using experimental data from literature for the case of controlled dynamic SSI experiments, and for operating OWTs. Additionally, the natural frequency provided by a technical document for the reference 15 MW OWT is compared to the result from the DSM, where a very good agreement is observed. The seismic response time-histories of the OWT model are obtained under different input earthquake conditions, and subsequently verified by comparison with the results of finite element simulations. The effects of different scour scenarios and foundation modelling approaches on the free vibration and seismic responses are subsequently investigated. A parametric analysis is also performed using different soil properties to observe the interaction between the soil stiffness, scour condition, and seismic response. Finally, the influence of the frequency content of seismic records on the dynamic response of the OWT, specifically the tower top acceleration, the mudline rotation, and the mudline stress, is investigated considering various scour scenarios. The specific numerical case study undertaken for a reference 15 MW OWT, which is supported by a large monopile in very dense sand, shows that the seismic responses are very limited and that the elastic soil behaviour assumption is reasonable. Additionally, considering the computational efficiency, the proposed combination of DSM and modal superposition can be used for rapid seismic performance assessment of large diameter monopile-supported OWTs at the preliminary design stage to gain insight to the global dynamic response of the whole vibrating system.