AbstractThe Mediterranean region (MR) is one of the climate change hot spots, posing serious threats to society. The insufficient resolution of the global climate models limits their capability to resolve the complex topography over MR, resulting in a large bias in climate variables. This study examines the performance of four Coupled Model Intercomparison Project phase six models from the High‐Resolution Model Intercomparison Project (HighResMIP) in reproducing the Mediterranean climate. A special focus is put on the role of oceanic and atmospheric model horizontal resolution and spread among the models. Various aspects, relevant to air‐sea interactions and precipitation are examined, including the mean, extremes, and associated mechanisms. All HighResMIP models reasonably well capture the large‐scale oceanic and atmospheric characteristics, but there is a sizable model‐to‐model difference. The Hadley Centre Global Environment Model and European Centre for Medium‐Range Weather Forecasts generally perform better than the other models at comparable atmospheric and oceanic horizontal resolutions. A finer oceanic resolution improves the representation not only of oceanic characteristics (i.e., sea surface temperature, SST) but also of the atmospheric processes (wind and precipitation). Likewise, increasing atmospheric model resolution benefits various atmospheric and ocean characteristics. Over some sub‐basins of the Mediterranean Sea, the intensification of surface wind speed results in the deepening of the ocean's mixed layer leading to cooling, indicating negative feedback in Wind‐SST. In contrast, in other regions, the warmer SST results in the intensification of wind (positive feedback in Wind‐SST).