Ten normal subjects and 14 patients with comitant esotropia were examined by means of pattern visual evoked responses (VER) under monocular and binocular viewing conditions. When both eyes were stimulated together a VER summation was noted both in normals and in strabismics with small-angle deviation and anomalous retinal correspondence (ARC). This is considered as an objective proof of binocularity. Patients with large-angle strabismus and/or suppression of the image of the deviated eye did not show summation. The significance of summation and its relationship with binocular vision was analyzed by recording binocular VER in normals in which diplopia was artificially induced and in strabismics who spontaneously exhibited double vision. A simple way for differentiating normals from strabismics by means of VERs is presented, considering that the presence or absence of summation per se does not achieve this result. This method is based on the anteposition in front of the fixing eye of neutral filters of increasing density. Summation disappears in strabismics with much weaker filters than in normals (0.5 versus 1.6 log. unit).
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