INTRODUCTION: Ascites is a major complication of cirrhosis with 50% mortality in 2 years. Large-volume paracentesis (LVP) is safe and effective treatment for refractory ascites. Complications include bowel perforation, infection, bleeding, and ascitic fluid leakage. Abdominal abscess in cirrhotic patients with ascites has not been reported as a complication of LVP. We present a patient admitted with septic shock and a large abdominal abscess that may have represented a complication of paracentesis. CASE DESCRIPTION/METHODS: A 54-yo woman with ascites due alcoholic cirrhosis and untreated chronic hepatitis C had been managed with LVP every 2 wks for last 4 yrs. 2 d after her last tap, she presented locally with abdominal pain, hypotensive and in shock. She received fluids, pressors and IV antibiotics. CT showed 22 × 14 × 5 cm abscess in the right side of abdomen extending into prerectal area with foci of gas without definite communication with the bowel (Figure 1 A-B). She was transferred to our facility where, on arrival, she was afebrile, hypotensive, tachycardiac with a distended, diffusely tender abdomen with rebound tenderness. Labs showed WBC of 25.3 × 103/mm3 (90% neutrophils), hemoglobin 6.9 g/dL, platelets 555 × 103/mm3, total bilirubin 7.7 mg/dL, albumin 2.2 g/dL. Patient was admitted to ICU for pressors and IV antibiotics. A drain was placed in the abscess; the fluid grew pan-sensitive Enterococcus faecium, E. coli, Lactobacillus, and Candida dubliniensis. Fungal coverage added and she was discharged on 3 wks of IV piperacillin-tazobactam and fluconazole. Repeat CT 2 wks later showed improvement of the abscess and ascites (Figure 2 A-B). Antibiotics were stopped after repeat CT 3 wks later showed continued improvement (Figure 3). Several wks later, patient was admitted to local hospital with abdominal discomfort. Paracentesis excluded SBP but she died few days later of multi-organ failure. DISCUSSION: Intra-abdominal abscess resulting from or associated with paracentesis has not been reported in the literature. Our patient presented in shock with a large abscess 2 d after her last tap. No definite evidence of bowel perforation was seen on imaging, but the possibility that the abscess was caused by bowel injury secondary to paracentesis cannot be excluded. Whether the abscess was caused by the last tap before her acute illness or was already present is unclear, as ascitic fluid labs were not obtained.Figure 1.: A-B. CT abdomen pelvis cross sectional and coronal view showing a 22 × 14 × 5 cm abscess in the right side of the abdomen extending into prerectal region with foci of gas without definite communication with the bowel (solid white arrows).Figure 2.: A-B: CT abdomen pelvis cross sectional and coronal view showing improvement in size of the abscess (solid white arrows) and ascites.Figure 3.: CT abdomen pelvis cross sectional 6 weeks later showing interval improvement of abscess (solid white arrow) and ascites.
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