Aphasic Language Research Articles

Increasing frequency of therapy by software-based treatment of naming ability in people with aphasia: a preliminary study

This study aimed to explore the effect of new software targeting naming deficits in Turkish-speaking people with aphasia. The study included seven Turkish people with aphasia. These participants took the Aphasia Language Assessment Test (ADD), Turkish Picture-Naming Test (T-RAT), and Technology Familiarity Assessment, and the words for therapy were determined. The selection of categories and words for inclusion in the application was based on the frequency and typicality features. The 12-week speech-language treatment sessions were divided into two sections. During the first six weeks, a speech-language pathologist (SLP) used the software to train people. After the first part, the SLP applied the T-RAT. Participants utilized the software at home in the second part. All participants took the ADD, T-RAT, and Software Evaluation Questionnaire following the second part. Participants’ naming abilities improved in all tests. Both therapy sessions with the SLP and those in which participants used the program independently demonstrated this improvement. Participants also reported high levels of treatment satisfaction. Cueing hierarchy approaches used in the software helped to improve naming skills in people with aphasia (PWA), independent of type, stage, or severity of aphasia. The findings of this study indicate that both sessions directed by an SLP and independent use of the software by participants can positively impact the therapy process with the developed software.

Micro- and Macrostructural Language Features in Vertebrobasilar or Carotid System Stroke Without Diagnosis of Aphasia.

This study aimed to investigate the macro- and microstructural features of language in patients with ischemic stroke without aphasia. Participants were grouped according to arterial system damage and given the Aphasia Language Assessment Test (ADD) to detect aphasia. A narrative sample was obtained and analyzed for macrostructural and microstructural features of the language. The study sample consisted of 31 participants with ischemic stroke (15 vertebrobasilar system [VBS] involvement and 16 carotid system [CS] involvement) and 31 healthy participants, totaling 62 individuals. The healthy control group scored higher than the stroke group on the microstructural feature type-token ratio and mean length of utterance in the narrative analysis and on the auditory comprehension, repetition, naming, grammar, speech act, and writing subtests in ADD. Effort behavior, errors, edits, repetitions, and pauses among microstructural features and uncertainty, filler expression, and anomia among macrostructural features were significantly higher in the vertebrobasilar and CS groups than in the healthy control group. The total ADD score and speech fluency and reading subtest scores were significantly higher in individuals with VBS damage than in individuals with CS lesions (p < .05). Language components may be impaired differently in patients with carotid and vertebrobasilar lesions. Speech and language disorders in individuals who have experienced cerebrovascular accidents should be evaluated in the subacute and chronic phases, and the therapeutic needs of patients with ischemic stroke should be determined, regardless of the presence of a clinical aphasia diagnosis.

Speech pauses in speakers with and without aphasia: A usage-based approach

Pauses in speech are indicators of cognitive effort during language production and have been examined to inform theories of lexical, grammatical and discourse processing in healthy speakers and individuals with aphasia (IWA). Studies of pauses have commonly focused on their location and duration in relation to grammatical properties such as word class or phrase complexity. However, recent studies of speech output in aphasia have revealed that utterances of IWA are characterised by stronger collocations, i.e., combinations of words that are often used together. We investigated the effects of collocation strength and lexical frequency on pause duration in comic strip narrations of IWA and non-brain-damaged (NBD) individuals with part of speech (PoS; content and function words) as covariate. Both groups showed a decrease in pause duration within more strongly collocated bigrams and before more frequent content words, with stronger effects in IWA. These results are consistent with frameworks which propose that strong collocations are more likely to be processed as holistic, perhaps even word-like, units. Usage-based approaches prove valuable in explaining patterns of preservation and impairment in aphasic language production.

Effects of Time Interval and Interference Manipulations on Word-Level Repetition and Naming Performance in Persons with Aphasia

Objectives: The purpose of this paper is to investigate the impact on the repetition and naming ability of Korean aphasia patients by controlling their working memory load through time intervals and interference effects using the Temple Assessment of Language and verbal Short-term memory in Aphasia (TALSA) protocol. In addition, we examined the phonological and lexical-meaning processing abilities of persons with aphasia through word repetition tasks, nonword repetition tasks, and picture naming tasks to examine phonological and lexical-meaning production abilities. Methods: Thirteen native Korean speakers with aphasia participated in the study, along with twelve control group participants. The word and nonword repetition tasks were conducted under three conditions to examine the time delay and interference effects. Each condition entailed listening to each ten words of two and three syllables. Similarly, the picture naming tasks were carried out under three conditions involving viewing ten pictures of two and three syllables each. Results: This study examined how the repetition and naming ability of persons with aphasia, i.e., the ability to producing phonemes and lexical-meaning of persons with aphasia, varies when adjusting the working memory load under time interval and interference effect conditions. This study found that the difference in performance between groups was significant for both tasks. In particular, the larger the time interval, the greater the interference effect; that is, the greater the load of working memory, the lower the performance of aphasia subjects compared to the control group. Conclusion: Since the aphasia subjects have poor working memory ability, the results of this study indicate that as the cognitive load increases, they are more affected by the ability to process phonological and semantic activations.

Assessment of communication-related quality of life in individuals with Alzheimer’s disease

ABSTRACT Purpose Alzheimer’s Disease is a neurodegenerative condition that affects individuals’ cognition, attention, behavior and language skills. With disease progression, problems are also observed in individuals’ participation in social life. Our aim was to investigate communition-related quality of life in individuals with Alzheimer's Disease and their language abilities. Method In this study, data were collected from a total of 47 Alzheimer’s Disease patients between the ages of 55–85. The Montreal Cognitive Assessment (MoCA), Aphasia Language Assessment (ADD), Aphasia Impact Questionnaire (AIQ-21) and Beck Depression tests were administered. The Alzheimer’s Disease Related Quality of Life (ADRQL) scale was administered to caregivers. Results and Conclusion As a result of the study, we found that there is a relationship between language and quality of life of individuals with Alzheimer’s Disease. The quality of life of individuals with Alzheimer’s Disease is affected in line with their language skills. In order to more thoroughly investigate this relationship, additional research should be conducted.

Revealing linguistic and verbal short-term and working memory abilities in people with severe aphasia

ABSTRACT Background The assessment of aphasia in people with severe deficits is hampered by a paucity of tests that are appropriate for this population and that are sensitive to their underlying linguistic and short-term and working memory (STM/WM) strengths and weaknesses. The Temple Assessment of Language and Short-Term Memory in Aphasia (TALSA) provides a means of assessing people with severe aphasia (PWSA). Aims The aim of this paper is to demonstrate the sensitivity of the TALSA to the underlying linguistic and STM/WM strengths and weaknesses in PWSA. We assessed eight PWSA on selected subtests of the TALSA and found that 1) the TALSA is sensitive to the underlying linguistic and verbal STM/WM abilities of PWSA, 2) the TALSA reveals a wide variety of linguistic and verbal STM/WM profiles in PWSA and, 3) the TALSA can potentially demonstrate common patterns of performance in PWSA. Main contributions The TALSA allows researchers to include more PWSA in the study of aphasia and enables clinicians to establish more accurate prognoses, create precisely targeted treatment plans and document incremental progress in therapy. Conclusions The TALSA is an important addition to the assessment of severe aphasia. It provides an in-depth evaluation of underlying linguistic and verbal STM/WM strengths and weaknesses of PWSA.

Abstract TP78: Characteristics of Verbal and Non-Verbal Cognitive Function in Post-Stroke Aphasia Based on Language-Cognition Neuropsychological Processing Model

Introduction: Post-stroke aphasia (PSA) patients have different levels of phonetic, lexical, semantic, syntactic, and other linguistic domain impairment, and accompanied by non-verbal cognitive impairment. However, the association between verbal and non-verbal cognitive functions is not fully understood.In this study, we used the Chinese Aphasia Language Battery (CALB) and Loewenstein Occupational Therapy Cognitive Assessment (LOTCA) to fully evaluate the characteristics of verbal and non-verbal cognitive function impairment in PSA patients. Methods: A total of 105 stroke patients were recruited in this study. Language and non-linguistic cognitive impairments were evaluated by CALB and LOTCA, respectively. Patients in the PSA group were subdivided into the fluent aphasia group (FAG) and the non-FAG group. Potential confounders were adjusted in the analysis of covariance. Partial correlation analysis between the subscores of CALB and LOTCA was also performed. Results: This study showed that PSA patients had worse speech analysis ability, vocabulary processing ability, semantic processing ability, syntactic structure conversion ability, and non-verbal cognitive performance(P&lt;0.001). Moreover, the scores of phonetic decoding, phonetic vocabulary production, noun category classification, total LOTCA, orientation, visual perception, motor use, and thinking operation were lower in the non-FAG compared with the FAG (p&lt;0.05). The total score of LOTCA was positively correlated with the aphasia quotient (r=0.637, P&lt;0.001) and scores of speech analysis ability, vocabulary processing ability, semantic processing ability, and syntactic structure conversion ability (r&gt;0; P&lt;0.0005). Conclusions: Based on the language-cognition neuropsychological processing model, this study adopted a comprehensive verbal and non-verbal cognitive assessment set of tests, and found that PSA patients have extensive phonological, lexical, semantic, syntactic, and grammatical processing disorders. Moreover, PSA patients often have more extensive and serious non-verbal cognitive impairments, and the severity of aphasia is significantly positively correlated with the degree of nonverbal cognitive impairment.

A Review of Causes and Countermeasures of Language Aphasia

At present, the Internet language is booming, new forms of expression emerge in an endless stream, and a series of Internet words spread quickly with simple and crude expressions. Many young people are unable to put their strong opinions or feelings into words when they want to express them so they fall into the situation of "word aphasia". There are three main manifestations of verbal aphasia, which can cause the degradation of personal expression and create language barriers. The paper explores the expression of verbal aphasia, the causes of verbal aphasia, the harm of verbal aphasia, and the solution to verbal aphasia. The research methods of study include the investigation analysis method, observation method, and so on. People can solve the problem of aphasia by insisting on reading, improving media literacy, and purifying the network environment. The study of verbal aphasia is mainly about the causes of this social imagination, the harm it can bring, and what strategies are available to solve it.

Analyzing Bei Dao's late poetry based on the expressions of exile

Bei Dao and the Misty Poetry group are defining events in world literary history, not only because of their early politically opposing compositions but also because of their progress in poetry abroad. Bei Dao experienced a harsh wander, and his poetry guidelines turned to personal and depoliticalized. However, the research proportion of Bei Dao’s later compositions is decreasing today, and many researchers and readers only summarize the invariable aspects of Bei Dao’s whole poetry span or interpret his later compositions with political ideas. This research mainly focuses on one aspect of Bei Dao’s later compositions, the unique expression of foreignness, homesickness, and loneliness, by collecting and analyzing a few poems Bei Dao wrote during his exile period. Consequently, this research excavates Bei Dao’s special recognition in his poems during his exile. He records his pointless, painful, and homesick feelings amid his unstable exile life. Besides, Bei Dao expresses many realizations, for example the unstoppable journey, identity separation, and the distance from the world. Moreover, the author raises a new concept, “native language aphasia”, to describe his identity separation through the deprivation of the native language.

Insights gained over 60 years on factors shaping post-stroke aphasia recovery: A commentary on Vignolo (1964)

Aphasia is an acquired language disorder resulting from brain injury, including strokes which is the most common etiology, neurodegenerative diseases, tumors, traumatic brain injury, and resective surgery. Aphasia affects a significant portion of stroke survivors, with approximately one third experiencing its debilitating effects in the long term. Despite its challenges, there is growing evidence that recovery from aphasia is possible, even in the chronic phase of stroke. Sixty years ago, Vignolo (1964) outlined the primary challenges confronted by researchers in this field. These challenges encompassed the absence of an objective evaluation of language difficulties, the scarcity of evidence regarding spontaneous aphasia recovery, and the presence of numerous variables that could potentially influence the process of aphasia recovery. In this paper, we discuss the remarkable progress that has been made in the assessment of language and communication in aphasia as well as in understanding the factors influencing post-stroke aphasia recovery.

A - 66 Non-Fluent/Agrammatic Variant of Primary Progressive Aphasia (Nappa) in a Bilingual Chinese Speaker: a Single-Case Study.

The non-fluent/agrammatic variant of primary progressive aphasia (naPPA) is a neurodegenerative syndrome associated with agrammatism in language production and effortful speech (Gorno-Tempini et al., 2011). There is limited literature on PPA in non-English speakers and few clinical cases of bilingual naPPA have been described (Tee et al., 2022; Zanini et al., 2011). Characteristics of symptoms in orthographic languages, such as Chinese, are not well understood (Ting et al., 2017). This case describes the assessment of naPPA in a bilingual Mandarin Chinese speaker. A 66-year-old Asian male with 16years of education complained of worsening aphasia in both languages over two years with initial preferential sparing of Chinese. A comprehensive neuropsychological battery was administered mostly in Chinese with select subtests in English. Language functioning was assessed with the Bilingual Aphasia Screening Test (Paradis & Libben, 1987). Agrammatism and apraxia of speech was present in both languages. Single-word comprehension and object knowledge was preserved, while comprehension of complex commands was impaired. Lexical discrimination of real and nonsense words was preserved. Delayed memory was impaired with relative improvement upon recognition. Attention, processing speed, visuospatial skills, and motor functioning were preserved. Mood was euthymic. This case revealed deficits in both languages with slower decline of the dominant language, suggesting that the less proficient language in bilinguals is more vulnerable to degeneration in naPPA.

Telepractice in speech-language pathology: Assessing remote speech discrimination

PurposeTo evaluate adult remote performance in speech discrimination on the Temple Assessment of Language and Short-term Memory in Aphasia (TALSA), and to compare to remote performance in NU-6 word repetition and participant ratings of self-perceived hearing ability obtained via remote session. MethodSixty older adults completed TALSA speech discrimination of concrete, low frequency words and of non-words via telephone. Remote repetition of words controlled for sound frequency was assessed using the Northwestern University (NU-6) word lists administered in live voice and recorded voice conditions. Forty-six of the participants completed questionnaires about their hearing via Zoom videoconference. ResultsMean performance in TALSA speech discrimination for words was similar to performance in NU-6 word repetition. Word repetition of NU-6 lists did not differ significantly for live voice versus recorded voice conditions. TALSA non-word speech discrimination was significantly worse than TALSA speech discrimination for words and was associated with age and self-reported hearing ability. ConclusionsTALSA speech discrimination can be administered remotely to evaluate potential perceptual influences on auditory comprehension. In remote assessment, participants demonstrated the expected pattern of more accurate speech discrimination for word stimuli than for non-words. The non-word TALSA condition may be particularly useful for detecting speech perception impairment, both in face-to-face and telepractice sessions. Similar performance of participants in both live voice and recorded conditions of the NU-6 word lists suggests that recordings used in SLP receptive language or memory assessment, including the TALSA, need not be abandoned in favor of live voice to support audition during telepractice.

Quantifying three types of abnormal language in semantic variant primary progressive aphasia

AbstractBackgroundPatients with the semantic variant of Primary Progressive Aphasia (svPPA) experience a gradual loss of semantic memory, impairing word retrieval and word comprehension. As such, svPPA patients often use superordinate, vague, and empty words. These patients often use language that refers to one’s own experience (“self‐referential”), one’s language impairments (“inability”), and/or contains tangents (“tangential”). These forms of aberrant language were identified previously as distinguishing svPPA from the other canonical variants of PPA (Gallee et al., 2021).MethodSpeech samples of the WAB picnic scene from 15 svPPA patients were analyzed by counting words and categorizing three forms of aberrant language at two timepoints (30 samples total), baseline and follow‐up (at least 12 months post baseline). Words were identified as self‐referential, inability, or tangential. Quantitative analyses were conducted to look for relationships between total word count and each of the three forms of aberrant language.ResultPreliminary results showed a strong correlation (r = .97) between the total number of aberrant words and the total number of words in the picture description transcriptions. At T1, 40% (6/15) used self‐referential words, 87% (13/15) used inability words, and 53% (8/15) used tangential words. At T2, 67% (10/15) used self‐referential words, 100% (15/15) used inability words, and 67% (10/15) used tangential words. Inability is the most prominent type of aberrant language. Longitudinal analyses are ongoing to investigate consistency or inconsistency within patients and relationship to aphasia severity.ConclusionPreliminary findings suggest patients with svPPA produce distinct types of aberrant language in a picture description task. The prominent use of inability words may be due to its scripted nature in that svPPA patients use these phrases repeatedly and may be related to disinhibition. Further, it is notable that several components of language not analyzed in this study, including grammar, syntax, and content units, are potentially informative. Using this method provides an efficient way to characterize speech of svPPA patients, which may lead to early subtyping, prognostication, and targeted treatment goals.Reference: Gallée,J.;Cordella,C.; Fedorenko, E.; Hochberg, D.; Touroutoglou, A.; Quimby, M.; Dickerson, B.C. Breakdowns in Informativeness of Naturalistic Speech Production in Primary Progressive Aphasia. Brain Sci. 2021,11, 130.

Transcranial Magnetic Stimulation for Post-Stroke Dyslexia 1 Case and Clinical Analysis

Objective: To investigate the efficacy of repetitive transcranial magnetic stimulation therapy combined with speech training on the speech function of patients with post-stroke aphasia, understanding the mechanisms of cognitive neuropsychological recovery in patients with dyslexia. METHODS: One case of aphasia patients was collected and treated with repetitive transcranial magnetic stimulation and speech therapy, and the patients' Chinese language aphasia examination assessment and hydrogen protons nuclear magnetic resonance spectroscopy results were collected before and after treatment. Based on the combination of neurocognitive psychological model, the relationship between the change of speech function and the dual-channel model before and after patients' repetitive transcranial magnetic stimulation combined with speech therapy was investigated. RESULTS: After 2 months of treatment, the patient's reading function, conversation, comprehension, repetition, and naming function improved when compared with before, and hydrogen protons nuclear magnetic resonance spectroscopy suggested that the patient's bilateral cerebral hemispheres Cr/Ch, and NAA/Cr all increased after treatment compared with before. Conclusion: Transcranial magnetic stimulation therapy combined with speech training can promote the increase of brain metabolites and improve patients' reading function, providing a new therapeutic idea for the treatment of post-stroke dyslexia, Meanwhile, the combination of repetitive transcranial magnetic stimulation technique and hydrogen proton MRI spectroscopy can be used as a non-invasive treatment-examination combination to explore the mechanisms of recovery from dyslexia.

Early within therapy naming probes as a clinically-feasible predictor of anomia treatment response

ABSTRACT This study investigated the relationship between early within-therapy probe naming performance and anomia therapy outcomes in individuals with aphasia. Thirty-four adults with chronic, post-stroke aphasia participated in the Aphasia Language Impairment and Functioning Therapy (Aphasia LIFT) programme, comprised of 48 h of comprehensive aphasia therapy. Sets of 30 treated and 30 untreated items identified at baseline were probed during impairment therapy which targeted word retrieval using a combined semantic feature analysis and phonological component analysis approach. Multiple regression models were computed to determine the relationship between baseline language and demographic variables, early within-therapy probe naming performance (measured after 3 h of impairment therapy) and anomia treatment outcomes. Early within-therapy probe naming performance emerged as the strongest predictor of anomia therapy gains at post-therapy and at 1-month follow-up. These findings have important clinical implications, as they suggest that an individual’s performance after a brief period of anomia therapy may predict response to intervention. As such, early within-therapy probe naming may provide a quick and accessible tool for clinicians to identify potential response to anomia treatment.

Motor rehabilitation of aphasic stroke patient: the possibility of Rood's approach.

Motor rehabilitation of aphasic stroke patient: the possibility of Rood's approach.

ASL MRI informs blood flow to chronic stroke lesions in patients with aphasia.

Introduction: Response to post-stroke aphasia language rehabilitation is difficult to anticipate, mainly because few predictors can help identify optimal, individualized treatment options. Imaging techniques, such as Voxel-based Lesion Symptom Mapping have been useful in linking specific brain areas to language behavior; however, further development is required to optimize the use of structural and physiological information in guiding individualized treatment for persons with aphasia (PWA). In this study, we will determine if cerebral blood flow (CBF) mapped in patients with chronic strokes can be further used to understand stroke-related factors and behavior. Methods: We collected perfusion MRI data using pseudo-Continuous Arterial Spin Labeling (pCASL) using a single post-labeling delay of 2,200ms in 14 chronic PWA, along with high-resolution structural MRI to compute maps of tissue damage using Tissue Integrity Gradation via T2w T1w Ratio (TIGR). To quantify the CBF in chronic stroke lesions, we tested at what point spatial smoothing should be applied in the ASL analysis pipeline. We then related CBF to tissue damage, time since stroke, age, sex, and their respective cross-terms to further understand the variability in lesion CBF. Finally, we assessed the feasibility of computing multivariate brain-behavior maps using CBF and compared them to brain-behavior maps extracted with TIGR MRI. Results: We found that the CBF in chronic stroke lesions is significantly reduced compared to its homologue grey and white matter regions. However, a reliable CBF signal (although smaller than expected) was detected to reveal a negative relationship between CBF and increasing tissue damage. Further, the relationship between the lesion CBF and age, sex, time since stroke, and tissue damage and cross-terms suggested an aging-by-disease interaction. This relationship was strongest when smoothing was applied in the template space. Finally, we show that whole-brain CBF relates to domain-general visuospatial functioning in PWA. The CBF-based brain-behavior maps provide unique and complementary information to structural (lesion-based) brain-behavior maps. Discussion: Therefore, CBF can be detected in chronic stroke lesions using a standard pCASL MRI acquisition and is informative at the whole-brain level in identifying stroke rehabilitation targets in PWAs due to its relationship with demographic factors, stroke-related factors, and behavior.

Improving Functional Communication Outcomes in Post-Stroke Aphasia via Telepractice: An Alternative Service Delivery Model for Underserved Populations.

Many persons with aphasia (PWA) have limited access to speech-language treatment (SLT) due to limited funding, speech-language pathologist shortages, geographical barriers, physical disabilities, transportation barriers, and the COVID-19 pandemic. The purpose of this study was to determine if telepractice is an effective and feasible service delivery model for PWA. Ten PWA completed 8 hours of remote treatment over 4 weeks. Synchronous telepractice sessions employed Oral Reading for Language in Aphasia (ORLA) and Conversational Script Training (CST). Pre- and post-assessment outcome measures included the Communication Activities of Daily Living-3 (CADL-3) and the Communication Confidence Rating Scale for Aphasia (CCRSA). Participants completed a telepractice satisfaction survey following post-assessment. All participants demonstrated improvements in CCRSA scores, total words produced correctly on trained CST stimuli, and total words produced correctly on trained ORLA stimuli. No differences were noted in CADL-3 scores. All participants were highly satisfied with telepractice as a service delivery model.

Aphasia Assessment: Translation of a Research Test Battery To A Practical Clinical Tool

<h3>Research Objectives</h3> To translate a research-based test of aphasia to a clinical version that maintains the theoretical and psychometric aspects of the research version and addresses the practical constraints of a busy health care setting. <h3>Design</h3> Based on the principles of implementation science we used a survey to elicit clinician input throughout the creation of a clinical version of the Temple Assessment of Language and Short-term Memory in Aphasia (TALSA). The survey was active for 15 months and was one component of a larger researcher-clinician partnership that included focus groups, case discussions, and training sessions. <h3>Setting</h3> Five clinical settings including one rehabilitation hospital, two acute care hospitals and two university clinics. <h3>Participants</h3> Clinical speech language pathologists. <h3>Interventions</h3> Not applicable. <h3>Main Outcome Measures</h3> Survey responses including Likert scale question data and short answers to the prompt, "Tell us about your experience with the TALSA." <h3>Results</h3> Survey results – 122 responses Likert scale questions: High level of satisfaction with test instructions (M = 6.56 on a 7-point Likert scale) and test administration (M = 6.54). Lower satisfaction reported for the usefulness of the TALSA in understanding individual patients' aphasia (M = 5.85) and the perceived value of the TALSA in setting therapy goals (M = 5.67). Open ended prompt – percentage of responses by topic: 34% quality of audio stimuli; 21% value of the TALSA; 13% quality of visual stimuli; 12% instructions; 5% interpretation. <h3>Conclusions</h3> Clinicians report that administration of the TALSA is quick and easy. High quality of audio stimuli and visual stimuli are important to clinicians. Higher audio and visual standards will be used in the creation of the second iteration of the Clinical TALSA. Guidance on interpretation of results needs further development. In partnership with clinicians, a treatment guide was created. This issue will be further addressed in a future implementation study. <h3>Author(s) Disclosures</h3> No conflicts of interest.

Development of a tailored intervention to implement an Intensive and Comprehensive Aphasia Program (ICAP) into Australian health services

ABSTRACT Background The Aphasia Language Impairment and Functioning Therapy (LIFT) program is one example of an Intensive and Comprehensive Aphasia Program (ICAP) developed in a research setting. This ICAP has shown promising improvements in naming, communication participation and communication-related quality of life, and is ready for translation into health services. However, there are challenges to implementing ICAPs into clinical services, including delivering high treatment doses with existing staffing, and providing a cohort model where patients start and finish concurrently. No Australian studies have investigated local clinicians’ or clinical stakeholders’ perspectives on translating the Aphasia LIFT program into existing health services. It is vital to understand the clinical context in which implementation is intended so that a theory-informed implementation intervention can be tailored to address identified barriers. Aims This study aimed to identify potential barriers and facilitators to implementing Aphasia LIFT into existing healthcare services from the perspectives of clinical stakeholders and experienced LIFT clinicians, and develop a theory-informed implementation intervention for Aphasia LIFT, tailored to the intended implementation context. Methods and Procedure This study comprised two distinct phases. In phase 1, qualitative semi-structured interviews were conducted with clinical stakeholders (n = 13) and Aphasia LIFT clinicians (n = 5) to identify key barriers and facilitators to Aphasia LIFT implementation. Interviews were informed by the Theoretical Domain Framework and data analysed using content analysis. In phase 2, barriers were mapped to behaviour change techniques and implementation strategies using two mapping approaches, leading to the development of the implementation intervention. Outcome and Results Combined clinical stakeholder and Aphasia LIFT clinician perspectives revealed six main barriers: ‘patient-level factors’, ‘environmental context and resources’, ‘beliefs about capabilities’, ‘the Aphasia LIFT innovation’, ‘knowledge’, and ‘skills’. Key implementation barriers included a perceived lack of flexibility of the Aphasia LIFT program’s structure, and an overall lack of confidence that the program could be feasibly delivered within a constrained healthcare environment. An implementation intervention was subsequently designed that incorporated six components: (i) Executive, leadership and stakeholder support, (ii) Allocation of clinical staff, (iii) Interactive education and training program, (iv) Resource procurement and provision, (v) Ongoing implementation support, and (vi) Consumer engagement and promotion. Conclusion The context-specific barriers and facilitators identified in this study informed the development of a tailored implementation intervention to facilitate translation of the Aphasia LIFT ICAP into clinical services. This implementation intervention will be evaluated in a future study.