Abstract

Objective: To investigate the efficacy of repetitive transcranial magnetic stimulation therapy combined with speech training on the speech function of patients with post-stroke aphasia, understanding the mechanisms of cognitive neuropsychological recovery in patients with dyslexia. METHODS: One case of aphasia patients was collected and treated with repetitive transcranial magnetic stimulation and speech therapy, and the patients' Chinese language aphasia examination assessment and hydrogen protons nuclear magnetic resonance spectroscopy results were collected before and after treatment. Based on the combination of neurocognitive psychological model, the relationship between the change of speech function and the dual-channel model before and after patients' repetitive transcranial magnetic stimulation combined with speech therapy was investigated. RESULTS: After 2 months of treatment, the patient's reading function, conversation, comprehension, repetition, and naming function improved when compared with before, and hydrogen protons nuclear magnetic resonance spectroscopy suggested that the patient's bilateral cerebral hemispheres Cr/Ch, and NAA/Cr all increased after treatment compared with before. Conclusion: Transcranial magnetic stimulation therapy combined with speech training can promote the increase of brain metabolites and improve patients' reading function, providing a new therapeutic idea for the treatment of post-stroke dyslexia, Meanwhile, the combination of repetitive transcranial magnetic stimulation technique and hydrogen proton MRI spectroscopy can be used as a non-invasive treatment-examination combination to explore the mechanisms of recovery from dyslexia.

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