The Laurentide Ice Sheet's (LIS) interior had a dynamic polythermal base, but the spatiotemporal variations of subglacial processes related to ice divide migration and other transient changes remain largely unknown, limiting our understanding of regional glacial dynamics. Previous studies focused on the regional glacial landform record, while ice sheet models lacked detailed parameterization within these regions, leading to an overestimation of cold-based subglacial conditions' extent and duration. In this study, glacial sediment dispersal patterns as identified by heavy minerals, clasts, and multivariate statistics of till matrix geochemistry were used to assess ice sheet dynamics within the Quebec–Labrador sector of the LIS. The earliest ice-flow phase produced and transported till across the study area (>175 km). However, major oxide data from till matrix geochemistry show a correlation with underlying bedrock, and this relationship is relatively common in areas of thin till cover and resistant bedrock lithologies. These results suggest a switch from an early phase of widespread erosion and long, sustained sediment transport to one of more limited erosion, perhaps abrasion dominant and shorter transport. Till compositional data and related dispersal patterns add supporting evidence to earlier ice sheet reconstructions based on ice-flow indicators and 10Be data together suggesting a transition from widespread uniform warm-based conditions during the earliest ice flow, followed by the development of an ice divide, its migration, and more sporadic warm-based conditions. Consequently, a thorough understanding of ice-flow history is essential for ice sheet modelling and future mineral exploration programs in inner ice sheet regions of the LIS.