We present a detailed numerical calculation of the upper critical field H c2 ( T) for a bulk extreme type-II superconductor. Particular emphasis is placed on the high-field, low-temperature regime of the HT-phase diagram. In this regime, it is necessary to go beyond the standard semi-classical theory and include the effects of Landau quantization of the electronic motion on the superconducting state. The presence of Landau level quantization induces an upward curvature in H c2 ( T) at ∼10% of T c0 for those superconducting systems in which the slope of H c2 ( T) at T c0 is ≥0.2 T/K. We construct a simple analytical model that can account for this behavior based on the renormalization of the BCS coupling constant by the off-diagonal pairing of electrons on Landau levels.