For approximately 100 years, the Houston region has been adversely impacted by land subsidence associated with excessive groundwater withdrawals. The rapidly growing population in the Houston region means the ongoing subsidence must be vigilantly monitored. Interferometric synthetic aperture radar (InSAR) has become a powerful tool for remotely mapping land-surface deformation over time and space. However, the humid weather and the heavy vegetation have significantly degraded the performance of InSAR techniques in the Houston region. This study introduced an approach integrating GPS and Sentinel-1 InSAR datasets for mapping long-term (2015–2019) and short-term (inter-annual, seasonal) subsidence within the greater Houston region. The root-mean-square (RMS) of the detrended InSAR-displacement time series is able to achieve a subcentimeter level, and the uncertainty (95% confidence interval) of the InSAR-derived subsidence rates is able to achieve a couple of millimeters per year for 5-year or longer datasets. The InSAR mapping results suggest the occurrence of moderate ongoing subsidence (~1 cm/year) in nothwestern Austin County, northern Waller County, western Liberty County, and the city of Mont Belvieu in Champers County. Subsidence in these areas was not recognized in previous GPS-based investigations. The InSAR mapping results also suggest that previous GPS-based investigations overestimated the ongoing subsidence in southwestern Montgomery County, but underestimated the ongoing subsidence in the northeastern portion of the county. We also compared the InSAR- and GPS-derived seasonal ground movements (subsidence and heave). The amplitudes of the seasonal signals from both datasets are comparable, below 4 mm within non-subsiding areas and over 6 mm in subsiding (>1 cm/year) areas. This study indicates that groundwater-level changes in the Evangeline aquifer are the primary reason for ongoing long-term and seasonal subsidence in the Houston region. The former is dominated by inelastic deformation, and the latter is dominated by elastic deformation. Both could cause infrastructure damage. This study demonstrated the potential of employing the GPS- and InSAR-integrated method (GInSAR) for near-real-time subsidence monitoring in the greater Houston region. The near-real-time monitoring would also provide timely information for understanding the dynamic of groundwater storage and improving both long-term and short-term groundwater resource management.